scholarly journals Year of the Mask; COVID-19 Challenges for Orthopaedic Surgery

2020 ◽  
Vol 10 ◽  
Author(s):  
Evert Smith
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Orthopaedic Surgery ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Virus Spread ◽  
Central Hospital ◽  
The World ◽  
Respiratory Physician ◽  
Novel Coronavirus

As a response to the viral pneumonias and severe illnesses that were emerging in patients, an ophthalmologist November 2019 a novel coronavirus emerged in Wuhan, Hubei, China Dr Li Wenliang, working at Wuhan Central Hospital, voiced his concerns only to be severely admonished by the authorities. The accelerated spread of the Severe Acute Respiratory Syndrome (SARS) in Wuhan, and then globally, as a result of the novel coronavirus was acute and pronounced. China alerted the World Health Organisation to several pneumonia cases at the end of December 2019 and the first death was recorded in early January 2020. The respiratory physician Dr Nanshan Zhong, announced human-to-human spread and a few days later on the 23 January 2020, Wuhan was placed under quarantine. The virus spread outside China and the WHO declared the outbreak a global health emergency on 30 January 2020. Tragically Dr Li Wenliang died on 7 February 2020 as a result of exposure to the virus, leaving a five-year-old son and a pregnant wife.

Comparative docking of SARS-CoV-2 receptors antagonists from repurposing drugs

2020 ◽  
Author(s):  
Micael Davi Lima de Oliveira ◽  
Kelson Mota Teixeira de Oliveira
Keyword(s):  
World Health Organisation ◽  
World Health ◽  
Lung Cells ◽  
The Novel ◽  
High Modulation ◽  
Main Protease ◽  
The World ◽  
Novel Coronavirus ◽  
Viral Receptors ◽  
Theoretical Results

According to the World Health Organisation, until 16 June, 2020, the number of confirmed and notified cases of COVID-19 has already exceeded 7.9 million with approximately 434 thousand deaths worldwide. This research aimed to find repurposing antagonists, that may inhibit the activity of the main protease (Mpro) of the SARS-CoV-2 virus, as well as partially modulate the ACE2 receptors largely found in lung cells, and reduce viral replication by inhibiting Nsp12 RNA polymerase. Docking molecular simulations were performed among a total of 60 structures, most of all, published in the literature against the novel coronavirus. The theoretical results indicated that, in comparative terms, paritaprevir, ivermectin, ledipasvir, and simeprevir, are among the most theoretical promising drugs in remission of symptoms from the disease. Furthermore, also corroborate indinavir to the high modulation in viral receptors. The second group of promising drugs includes remdesivir and azithromycin. The repurposing drugs HCQ and chloroquine were not effective in comparative terms to other drugs, as monotherapies, against SARS-CoV-2 infection.

scholarly journals Ghana and the COVID-19 pandemic

2020 ◽  
Vol 54 (4s) ◽  
pp. 1-2
Author(s):  
David Ofori-Adjei ◽  
Margaret Lartey ◽  
Kwadwo A. Koram
Keyword(s):  
Tract Infection ◽  
Severe Acute Respiratory Syndrome ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
World Health Organisation ◽  
World Health ◽  
Virus Spread ◽  
Global Pandemic ◽  
The World

A new virus causing predominantly respiratory tract infection was described in China late 2019. The virus was subsequently named the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes as COVID-19. Subsequently the virus spread to many parts of the world. This resulted in the World Health Organisation declaring COVID-19 a global pandemic on 11th March 2020.

COVID-19: Socio-Economic Consequences on the Hospitality Industry in Malaysia

2021 ◽  
Vol 12 (1) ◽  
pp. 52-52
Author(s):  
Nur Hidayah Che Ahmat ◽  
Syafiqah Rahamat ◽  
Susan Wohlsdorf Arendt
Keyword(s):  
Public Health ◽  
Hospitality Industry ◽  
Economic Consequences ◽  
World Health ◽  
The Novel ◽  
Virus Spread ◽  
The World ◽  
Control And Prevention ◽  
Novel Coronavirus ◽  
Health Organization

The novel Coronavirus disease (COVID-19) first appeared in December 2019 in Wuhan, Hubei Province China before emerging in neighbouring countries in early 2020. The World Health Organization (WHO) declared COVID-19 a pandemic when the spreading of the virus started accelerating in many parts of the world and killing thousands of people. As of 22nd May 2021, there were more than 166 million confirmed cases with more than 147 million recovered and nearly 3.5 million deaths (Worldometers, n.d.). According to the WHO (2020) and Centers for Disease Control and Prevention (2020), the virus easily spreads through coughing and sneezing. Therefore, many countries implemented social distancing between individuals and various other restriction orders or recommendations (e.g., stay-at-home policies, closure of non-essential businesses) to help curb virus spread. How governments in each country reacted to control the spread of the virus appeared crucial to mitigate public health and economic impacts. Keywords: Foodservice, Hospitality, Hotel, Malaysia, Pandemic

scholarly journals The Socio-Economic Ramifications of the Covid-19 Pandemic: The Case of Ghana

2021 ◽  
Author(s):  
Richmond Sam Quarm ◽  
Rosemond Sam-Quarm ◽  
Richmond Sam-Quarm
Keyword(s):  
Rational Choice Theory ◽  
Choice Theory ◽  
Respiratory Illness ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Cross Sectional ◽  
The World ◽  
The Government ◽  
Novel Coronavirus

The novel, dreaded, disruptive, and disastrous Covid-19 pandemic took the world by storm in January, 2020. The Covid-19 pandemic in Ghana is part of the worldwide coronavirus disease caused by “severe acute respiratory syndrome (SARS-CoV-2)”. On 12th January, 2020 the World Health Organisation (WHO) confirmed that the novel coronavirus was the cause of a respiratory illness that affected a cluster of people in Wuhan City, Hubei Province, China. This was reported to the WHO on 31st December, 2019. On 11th March, 2020, WHO declared the novel Covid-19 a global pandemic (Graphic Online, 2020a). It is worthy to note how the Government of Ghana, political parties, citizens, scientists and academia, corporate entities, faith based organisations, traditional rulers, have offered varied forms of interventions to combat the scourge. The Theoretical Framework of this research was underpinned by the Theory of Epidemics, the Agency Theory, the Rational Choice Theory, and the Stakeholder Theory. We conducted a cross-sectional research through non-probability and purposive sampling with 250 respondents. We also employed face-to-face interviews, structured closed-ended and open-ended Questionnaires (Braun and Clarke, 2012; Denzin, 2017), which were administered online through email application via Google Forms. One of our major findings was that with the approval of Pfizer/BioNTech Covid-19 vaccine by the UK’s MHRA on 1st December, 2020 (Graphic Online, 2020b); and subsequently by the US FDA a week later on 8th December, 2020 (Graphic Online, 2020c), all governments around the globe in general, but Africa in particular, must make conscious efforts backed by adequate budgetary allocations to secure maximum quantities of the vaccines for their vulnerable teeming population.

scholarly journals The Socio-Economic Ramifications of the Covid-19 Pandemic: The Case of Ghana

2021 ◽  
Author(s):  
Richmond Sam Quarm ◽  
Rosemond Sam-Quarm ◽  
Richmond Sam-Quarm
Keyword(s):  
Rational Choice Theory ◽  
Choice Theory ◽  
Respiratory Illness ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Cross Sectional ◽  
The World ◽  
The Government ◽  
Novel Coronavirus

The novel, dreaded, disruptive, and disastrous Covid-19 pandemic took the world by storm in January, 2020. The Covid-19 pandemic in Ghana is part of the worldwide coronavirus disease caused by “severe acute respiratory syndrome (SARS-CoV-2)”. On 12th January, 2020 the World Health Organisation (WHO) confirmed that the novel coronavirus was the cause of a respiratory illness that affected a cluster of people in Wuhan City, Hubei Province, China. This was reported to the WHO on 31st December, 2019. On 11th March, 2020, WHO declared the novel Covid-19 a global pandemic (Graphic Online, 2020a). It is worthy to note how the Government of Ghana, political parties, citizens, scientists and academia, corporate entities, faith based organisations, traditional rulers, have offered varied forms of interventions to combat the scourge. The Theoretical Framework of this research was underpinned by the Theory of Epidemics, the Agency Theory, the Rational Choice Theory, and the Stakeholder Theory. We conducted a cross-sectional research through non-probability and purposive sampling with 250 respondents. We also employed face-to-face interviews, structured closed-ended and open-ended Questionnaires (Braun and Clarke, 2012; Denzin, 2017), which were administered online through email application via Google Forms. One of our major findings was that with the approval of Pfizer/BioNTech Covid-19 vaccine by the UK’s MHRA on 1st December, 2020 (Graphic Online, 2020b); and subsequently by the US FDA a week later on 8th December, 2020 (Graphic Online, 2020c), all governments around the globe in general, but Africa in particular, must make conscious efforts backed by adequate budgetary allocations to secure maximum quantities of the vaccines for their vulnerable teeming population.

COVID-19 Disease

2020 ◽  
pp. 957-957
Author(s):  
Christopher P. Conlon ◽  
John D. Firth
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
World Health Organisation ◽  
Central China ◽  
World Health ◽  
The World ◽  
Novel Coronavirus ◽  
Wet Market ◽  
The City

A novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2), first appeared in the city of Wuhan in Central China in December 2019. Initial cases appeared to be centred on a so-called wet market, but the outbreak spread rapidly. The World Health Organisation (WHO) declared a Pandemic Health Emergency of International Concern on 30 January, 2020. At the time of writing, there have been over 11 million cases globally and more than 500,000 deaths.

scholarly journals The Socio-Economic Ramifications of the Covid-19 Pandemic: The Case of Ghana

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Richmond Sam Quarm ◽  
◽  
Rosemond Sam-Quarm ◽  
Richmond Sam-Quarm ◽  
◽  
...  
Keyword(s):  
Rational Choice Theory ◽  
Choice Theory ◽  
Respiratory Illness ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Cross Sectional ◽  
The World ◽  
The Government ◽  
Novel Coronavirus

The novel, dreaded, disruptive, and disastrous Covid-19 pandemic took the world by storm in January, 2020. The Covid-19 pandemic in Ghana is part of the worldwide coronavirus disease caused by “severe acute respiratory syndrome (SARS-CoV-2)”. On 12th January, 2020 the World Health Organisation (WHO) confirmed that the novel coronavirus was the cause of a respiratory illness that affected a cluster of people in Wuhan City, Hubei Province, China. This was reported to the WHO on 31st December, 2019. On 11th March, 2020, WHO declared the novel Covid-19 a global pandemic (Graphic Online, 2020a). It is worthy to note how the Government of Ghana, political parties, citizens, scientists and academia, corporate entities, faith based organisations, traditional rulers, have offered varied forms of interventions to combat the scourge. The Theoretical Framework of this research was underpinned by the Theory of Epidemics, the Agency Theory, the Rational Choice Theory, and the Stakeholder Theory. We conducted a cross-sectional research through non-probability and purposive sampling with 250 respondents. We also employed face-to-face interviews, structured closed-ended and open-ended Questionnaires (Braun and Clarke, 2012; Denzin, 2017), which were administered online through email application via Google Forms. One of our major findings was that with the approval of Pfizer/BioNTech Covid-19 vaccine by the UK’s MHRA on 1st December, 2020 (Graphic Online, 2020b); and subsequently by the US FDA a week later on 8th December, 2020 (Graphic Online, 2020c), all governments around the globe in general, but Africa in particular, must make conscious efforts backed by adequate budgetary allocations to secure maximum quantities of the vaccines for their vulnerable teeming population.

scholarly journals Comparative docking of SARS-CoV-2 receptors antagonists from repurposing drugs

2020 ◽  
Author(s):  
Micael Davi Lima de Oliveira ◽  
Kelson Mota Teixeira de Oliveira
Keyword(s):  
World Health Organisation ◽  
World Health ◽  
Lung Cells ◽  
The Novel ◽  
High Modulation ◽  
Main Protease ◽  
The World ◽  
Novel Coronavirus ◽  
Viral Receptors ◽  
Theoretical Results

According to the World Health Organisation, until 16 June, 2020, the number of confirmed and notified cases of COVID-19 has already exceeded 7.9 million with approximately 434 thousand deaths worldwide. This research aimed to find repurposing antagonists, that may inhibit the activity of the main protease (Mpro) of the SARS-CoV-2 virus, as well as partially modulate the ACE2 receptors largely found in lung cells, and reduce viral replication by inhibiting Nsp12 RNA polymerase. Docking molecular simulations were performed among a total of 60 structures, most of all, published in the literature against the novel coronavirus. The theoretical results indicated that, in comparative terms, paritaprevir, ivermectin, ledipasvir, and simeprevir, are among the most theoretical promising drugs in remission of symptoms from the disease. Furthermore, also corroborate indinavir to the high modulation in viral receptors. The second group of promising drugs includes remdesivir and azithromycin. The repurposing drugs HCQ and chloroquine were not effective in comparative terms to other drugs, as monotherapies, against SARS-CoV-2 infection.

scholarly journals Worldwide Trend Analysis and Potential Spread Prediction of SARS-CoV-2

2020 ◽  
Author(s):  
Arohi Jain ◽  
Aswin S ◽  
Jais Jose ◽  
Deepa Nathalia ◽  
Arjun Suresh
Keyword(s):  
Meteorological Factors ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Actual Number ◽  
Pollution Levels ◽  
Major Disaster ◽  
The World ◽  
Novel Coronavirus ◽  
Almost All

Abstract Covid-19 declared as a pandemic by the World Health Organisation on January 30, 2020, is a major disaster which shook the roots of almost all the economies around the globe. The outbreak began in a city of China, Wuhan majorly due to consumption of bats during December. The symptoms, the ways of spreading of infection are quite similar to that of influenza. The areas with higher pollution levels of particulate matter have reported a higher number of deaths as compared to the number of deaths in the cases from comparatively less polluted areas. The meteorological factors have also played a major role in the extent of spread of disease and the ability of humans living in the area to fight against the disease. Social distancing and lockdown all over the nation have proved to be major weapons to fight against the further spread of disease. The lockdown, on the other hand, has given relief from the high levels of pollution resulting in good air quality and clean rivers. This study focuses on the spread of the novel coronavirus all over the world with the trend in the number of confirmed cases, deaths and the cured from the onset and also highlighting the situations in five countries. The study further gives a prediction of the number of cases for ten days and correlates the values with the actual number of cases reported and throws light on the future aspects of the infection.

scholarly journals Does the novel coronavirus 2019 like heart more than the other family members of coronaviruses?

2020 ◽  
Vol 12 (2) ◽  
pp. 156-157
Author(s):  
Mohammad Mostafa Ansari Ramandi ◽  
Mohammadreza Baay ◽  
Nasim Naderi
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Family Members ◽  
Middle East Respiratory Syndrome ◽  
The Other ◽  
The Novel ◽  
The World ◽  
Future Challenges ◽  
Novel Coronavirus ◽  
Coronavirus Infections

The disaster due to the novel coronavirus disease 2019 (COVID-19) around the world has made investigators enthusiastic about working on different aspects of COVID-19. However, although the pandemic of COVID-19 has not yet ended, it seems that COVID-19 compared to the other coronavirus infections (the Middle East Respiratory Syndrome [MERS] and Severe Acute Respiratory Syndrome [SARS]) is more likely to target the heart. Comparing the previous presentations of the coronavirus family and the recent cardiovascular manifestations of COVID-19 can also help in predicting possible future challenges and taking measures to tackle these issues.

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