scholarly journals Frecuencia de dermatomicosis y factores asociados en población vulnerable de la ciudad de Manizales. Colombia. 2011

2016 ◽  
Vol 18 (6) ◽  
pp. 953
Author(s):  
Gloria Ines Estrada Salazar ◽  
José A. Chacón-Cardona
Keyword(s):  
Candida Albicans ◽  
Trichophyton Rubrum ◽  
Culture Media ◽  
Trichophyton Mentagrophytes ◽  
Direct Analysis ◽  
Microsporum Gypseum ◽  
Epidermophyton Floccosum ◽  
Palabras Clave ◽  
Fusarium Sp ◽  
Cutaneous Mycosis

Resumen:Objetivo: Determinar la frecuencia de las dermatomicosis en personas de diferentes instituciones de atención social en la ciudad de Manizales durante el año 2011. Método: Mediante la toma de muestras de los sitios que presentaban algún tipo de lesión sospechosa de ser una micosis cutánea, se hizo un análisis directo con KOH y cultivo en medios de Saboureaud y Mycosel. Se aplicó un instrumento de recolección de información para establecer  factores asociados con la presencia de estos microorganismos.Resultados: Los hongos levaduriformes encontrados con mayor frecuencia fueron: Candida albicans, Trichosporon sp, y los mohos saprofitos Penicillium sp, fusarium sp; seguido de hongos dermatofitos como: Trichophyton mentagrophites, Trichophyton rubrum, Epidermophyton floccosum y Microsporum gypseum. Las lesiones secas y descamativas se encontraron con mayor frecuencia. El compartir baños y vivir en hacinamiento y el uso de elementos comunes fueron los factores asociados más importantes en este estudio.Conclusiones. Las dermatomicosis son frecuentes en poblaciones vulnerables y se asocian a diferentes factores muy similares a los encontrados en otros estudios de igual naturaleza.    Palabras clave: dermatomicosis, onicomicosis, jóvenes, ancianos, factores asociados. Summary:Objective: To determine the frequency of ringworm in people of different social care institutions in the city of Manizales in 2011.Method: Using the sampling sites that had some kind of suspicious lesion from a cutaneous mycosis, direct analysis with KOH and culture media was Saboureaud and Mycosel. An instrument of data collection was used to establish factors associated with the presence of these microorganisms.Results: The yeast found most frequently were: Candida albicans, Trichosporon sp and Penicillium molds saprophytes sp, Fusarium sp, followed by dermatophyte fungi such as Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum. Dry scaly lesions were found more frequently. The shared bathrooms and living in overcrowded and the use of common elements were the most important in this study associated factors.Conclusions: Dermatomycoses are common in vulnerable populations and are associated with different very similar to those found in other studies of the same nature factors. Keywords: ringworm, onychomycosis, young, old, associated factors.

scholarly journals Antifungal Activity of Eugenia umbelliflora against Dermatophytes

2009 ◽  
Vol 4 (9) ◽  
pp. 1934578X0900400 ◽  
Author(s):  
Karina E. Machado ◽  
Valdir Cechinel Filho ◽  
Rosana C. B. Cruz ◽  
Christiane Meyre-Silva ◽  
Alexandre Bella Cruz
Keyword(s):  
Antifungal Activity ◽  
Betulinic Acid ◽  
Fungal Pathogens ◽  
Trichophyton Rubrum ◽  
Trichophyton Mentagrophytes ◽  
Microsporum Canis ◽  
Microsporum Gypseum ◽  
Epidermophyton Floccosum ◽  
Agar Dilution

Antifungal activities of Eugenia umbelliflora Berg. (Myrtaceae) were tested in vitro against a panel of standard and clinical isolates of human fungal pathogens (dermatophytes and opportunistic saprobes). Methanol extracts of leaves and fruits of E. umbelliflora were separately prepared and partitioned, to yield dichloromethane (DCM), ethyl acetate (EtOAc) and aqueous fractions (Aq). Three compounds (1-3) were obtained from the DCM extract using chromatographic procedures. Antifungal assays were performed using agar dilution techniques. Both extracts (fruits and leaves), their DCM and EtOAc fractions, and compound 2 (betulin and betulinic acid) presented selective antifungal activity against dermatophytes (Epidermophyton floccosum, Microsporum canis, Microsporum gypseum, Trichophyton rubrum, Trichophyton mentagrophytes), with MIC values between 200 and 1000 μg/mL, and interestingly, inhibited 4/5 species with MIC values of ≤500 ≤g/mL. The aqueous fractions of fruits and leaves, and compounds 1 (α, β amyrin) and 3 (taraxerol) were inactive up to the maximum concentrations tested (1000 μg/mL).

scholarly journals Honey and Propolis have Antifungal Property against Select Dermatophytes and Candida albicans

2020 ◽  
Vol 54 (1) ◽  
Author(s):  
Maria Christina R. Batac ◽  
Mary Ann C. Sison ◽  
Cleofas R. Cervancia ◽  
Marie Eleanore O. Nicolas
Keyword(s):  
Candida Albicans ◽  
Trichophyton Rubrum ◽  
Diffusion Method ◽  
Microsporum Gypseum ◽  
Zone Of Inhibition ◽  
Disk Diffusion Method ◽  
Epidermophyton Floccosum ◽  
Propolis Extract ◽  
Antifungal Properties ◽  
Zones Of Inhibition

Objective. To determine the antifungal properties of honey from two different floral sources (sunflower and coconut) and Philippine propolis against selected dermatophytes and Candida albicans. Methods. The minimum inhibitory concentration (MIC) of honey and propolis against Trichophyton rubrum, T. mentagrophytes, Microsporum gypseum, Epidermophyton floccosum and Candida albicans was determined using the broth macrodilution method (NCCLS M38-P). Disk diffusion method was used to determine the zones of inhibition. Clotrimazole served as comparator drug. Results. Sunflower and coconut honey inhibited all test fungi, with coconut honey yielding lower MICs. However, propolis performed better than both sunflower and coconut honey. T. mentagrophytes was most sensitive to the test agents. Zones of inhibition were not produced by sunflower honey for Trichophyton mentagrophytes, Microsporum gypseum, and Epidermophyton floccosum; by coconut honey for Microsporum gypseum, and by propolis for Epidermophyton floccosum. No zone of inhibition was exhibited by honey and propolis for Candida albicans. Conclusion. Honey and aqueous propolis extract exhibit antifungal properties against Trichophyton rubrum, T. mentagrophytes, Microsporum gypseum, Epidermophyton floccosum and Candida albicans. Although honey and propolis have inhibitory activities against these organisms, clotrimazole is still relatively superior based on the zone of inhibition produced by the test drugs.

scholarly journals Antifungal activity and mechanism of heat-transformed ginsenosides from notoginseng against Epidermophyton floccosum, Trichophyton rubrum, and Trichophyton mentagrophytes

RSC Advances ◽  
2017 ◽  
Vol 7 (18) ◽  
pp. 10939-10946 ◽  
Author(s):  
Peng Xue ◽  
Xiushi Yang ◽  
Xiaoyan Sun ◽  
Guixing Ren
Keyword(s):  
Antifungal Activity ◽  
Trichophyton Rubrum ◽  
Trichophyton Mentagrophytes ◽  
Epidermophyton Floccosum ◽  
Heat Transformation

The improved antifungal activity of notoginseng can be attributed to the formation of less polar ginsenosides by heat transformation.

scholarly journals Dermatofitosis humana en una comunidad con desigualdad social, Ayacucho 2018

2019 ◽  
Vol 27 (1) ◽  
Author(s):  
Serapio Romero Gavilán
Keyword(s):  
Trichophyton Rubrum ◽  
Trichophyton Mentagrophytes ◽  
Microsporum Canis ◽  
Microsporum Gypseum

Trabajo de investigación desarrollado con el objetivo de conocer la frecuencia de la dermatofitosis humana en una comunidad con desigualdad social. Hipótesis: la dermatofitosis humana es una afección fúngica muy frecuente en comunidades con desigualdad social. Zona de estudio: comunidad con desigualdad social periurbana de la ciudad de Ayacucho. Tipo de estudio: no experimental. Diseño de estudio: descriptivo-transversal. Muestra: no probabilística, individuos con signos de afecciones compatibles a micosis superficial. Metodología: muestras de escamas de piel, pelos, fragmentos de uñas de pies y manos, escamas de planta, espacios interdigitales y otras partes de cuerpo, fueron tomadas con una hoja de bisturí de filo romo o con el borde de un portaobjetos previa desinfección con alcohol al 70% y colocadas en sobres de papel oscuro etiquetados, en el laboratorio de Epidemiología y Micología de la Universidad Nacional de San Cristóbal de Huamanga, se realizó la observación directa con KOH al 20% y la siembra en placas Petri conteniendo Agar Sabouraud y Agar selectivo para hongos patógenos, después de una incubación a 25ºC por hasta 14 días; las colonias coincidentes con dermatofitos fueron observados al microscopio para identificarlos. Resultados: se ha encontrado que 85/153 (55,5%) presentaron diversas formas de dermatofitosis, no se observó preferencia de la dermatofitosis humana con relación al género (p> 0,05), los factores asociados a la dermatofitosis determinados estadísticamente (p< 0,05) fueron la higiene, el piso de la vivienda y la crianza de animales, se han identificado las especies de Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis y Microsporum gypseum.

scholarly journals In vitro evaluation of the antifungal activity of Marco (Ambrosia arborescens Mill.) and Matico (Aristeguietia glutinosa Lam.) on the pathogenic fungi that cause dermatomycosis (ringworm)

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 559
Author(s):  
Tatiana de los Ángeles Mosquera Tayupanta ◽  
Sandra Elizabeth Ayala Valarezo ◽  
Tatiana Alexandra Vasquez Villareal ◽  
María Belén Montaluisa Álvarez
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Trichophyton Rubrum ◽  
Therapeutic Potential ◽  
Pathogenic Fungi ◽  
Trichophyton Mentagrophytes ◽  
Microsporum Canis ◽  
The One ◽  
One Way Anova

Background: Currently, there is a trend towards using natural and ethnopharmacological species with therapeutic potential. This investigation evaluated the antifungal activity of two species in the Ecuadorian Andes, which are used in treating dermatomycosis: Ambrosia arborescens Mill. (Marco) and Aristeguietia glutinosa Lam. (Matico). Methods: We worked with seven concentrations (100 to 700ppm) of Ambrosia arborescens Mill. extract and ten concentrations (0.5 to 5%) of essential oil (EO) of Aristeguietia glutinosa Lam. on Trichophyton mentagrophytes ATCC 9533, Trichophyton rubrum ATCC 28188, Microsporum canis ATCC 36299 and Candida albicans ATCC 10231. The methodology used was a modified version of the Kirby-Bauer method, using diffusion in agar wells. Results: The Tukey test, after the one-way Anova, determined effective concentrations of EO: 5% for Trichophyton mentagrophytes, 4.5% for Trichophyton rubrum, 5% for Microsporum canis and 2% for Candida albicans. In the extracts, the concentration of 700ppm was used for Trichophyton mentagrophytes, Trichophyton rubrum, and 600ppm for Microsporum canis and Candida albicans. Conclusions: The evaluation of the antifungal activity of the Ambrosia arborescens extract showed inhibition in the studied dermatophytes in each one of the planted concentrations (100 to 700ppm). The evaluation of the antifungal activity of Aristeguietia glutinosa EO showed inhibition in the studied dermatophytes in each of the planted concentrations (0.5 to 5%).

scholarly journals Tinha do couro cabeludo em crianças de Goiânia, Brasil

2003 ◽  
Vol 36 (6) ◽  
pp. 653-655 ◽  
Author(s):  
Tatiana Dias ◽  
Orionalda de Fátima Lisboa Fernandes ◽  
Ailton José Soares ◽  
Xisto Sena Passos ◽  
Milce Costa ◽  
...  
Keyword(s):  
Trichophyton Rubrum ◽  
Trichophyton Mentagrophytes ◽  
Microsporum Canis ◽  
Microsporum Gypseum ◽  
Trichophyton Tonsurans

Durante o período de janeiro de 1999 a julho de 2002 um total de 164 casos de tinha do couro cabeludo foram diagnosticados através de exames micológicos, realizados no Instituto de Patologia Tropical e Saúde Pública da Universidade Federal de Goiás. Destes pacientes, 94 (57,3%) pertenciam ao sexo masculino, com idades variando de 3 meses a 13 anos. O diagnóstico e identificação dos agentes de dermatofitoses do couro cabeludo foram feitos utilizando-se exame direto com KOH a 20% e cultivo em ágar Mycobiotic e em ágar Sabouraud dextrose acrescido de cloranfenicol. As seguintes espécies foram identificadas: Microsporum canis (71,3%), Trichophyton tonsurans (11%), Trichophyton mentagrophytes (7,9%), Trichophyton rubrum (6,7%) and Microsporum gypseum (3%). Nossos estudos mostraram que o fungo de habitat natural no animal (zoofílico), Microsporum canis foi o agente mais comum de lesões no couro cabeludo em humanos.

scholarly journals Fungal lesions of the nail plate in patients from the Warmian-Masurian Voivodeship - analysis and discussion of the results of studies carried out in 2014 - 2019

2020 ◽  
pp. 41-45
Keyword(s):  
Candida Albicans ◽  
Candida Parapsilosis ◽  
Trichophyton Rubrum ◽  
Nail Plate ◽  
Trichophyton Mentagrophytes ◽  
Etiologic Agent ◽  
Etiological Factors ◽  
Positive Results

Introduction: The aim of the study was to analyze the results of mycological cultures obtained in the years 2014-2019. The study included an analysis of the incidence of mycosis with regard to their location, as well as the proportion of individual etiological factors in the infection. Methods: The study included materials from 999 patients who gave a total of 1103 cultures. The material was taken directly from the material and mycological cultures were established. Results: Positive results accounted for 35,8%. Trichophyton rubrum (44.2%) was the most common etiologic agent of dermatophytes. Among the yeast-like fungi, Candida albicans (8.8%) and Candida parapsilosis (7,6%) were the most common. Conclusions: Infectious lesions were mainly caused by dermatophytes, where Trichophyton rubrum and Trichophyton mentagrophytes dominated.

scholarly journals Efficacy of Neem Kernel Bioactives Extracted using Supercritical Fluid Carbon Dioxide on Selected Dermatophytes and Foodborne Pathogens

2019 ◽  
Vol 9 (1) ◽  
pp. 4304-4309
Keyword(s):  
Carbon Dioxide ◽  
Candida Albicans ◽  
Supercritical Fluid ◽  
Foodborne Pathogens ◽  
Candida Parapsilosis ◽  
Trichophyton Rubrum ◽  
Trichophyton Mentagrophytes ◽  
Aspergillus Ochraceus ◽  
Seed Kernel ◽  
Supercritical Fluid Carbon Dioxide

Neem seed kernel was subjected to supercritical fluid carbon dioxide (SCF) process and evaluated for the inhibition of selected dermatophytes such as Candida albicans, Candida tropicalis, Candida parapsilosis, Trichophyton rubrum, Trichophyton mentagrophytes. The extraction was carried out by SCF-CO2 at 300 bar 50 °C with and without entrainer (30 % methanol and acidified methanol). Results showed that the inhibition of the growth of all the dermatophytes is maximum in the extract obtained at 300 bar 50 °C with methanol (SCF-Me) followed by 300 bar 50 °C without methanol (SCF). The acidified SCF (SCF-MeA) extract did not show any remarkable inhibition. Of the dermatophytes, SCF-Me showed the inhibition against Candida parapsilosis of 18.46±0.25 mm compared to Candida albicans 16±0.26 mm, whereas the methanol control exhibited 10±0.3 mm inhibition. Out of the two fungal organisms, SCFMe inhibited the growth of Trichophyton rubrum and Trichophyton mentagrophytes at 21.53±0.23 mm and 18.1±0.1 mm respectively. The extracts were also evaluated for its inhibition against the foodborne pathogens (bacteria, fungi, and yeast). The SCF-Me extract showed maximum inhibition against Pseudomonus aeroginosa (27.26±0.25) compared to Bacillus subtilis (24.36±0.35) at the concentration of 70mg. In fungus, Aspergillus ochraceus (16.7±0.60) was maximum when compared to Aspergillus niger (15.2±0.43) and yeast exhibited the inhibition of 15.93±0.20 at the concentration of 80mg. The dermatophytic and antimicrobial activity of the SCF-Me extract is due to the presence of higher amount of triterpenoinds such as Azadirachtin (50.7 %), 6-deacetyl nimbin (0.14 %), Nimbin (0.08 %), Salannin (1.83 %) and Epoxy azadiradione (1.58 %) which were confirmed by liquid chromatography and mass spectroscopy (LC-MS).

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