scholarly journals Treadmill walking differently affects body composition and metabolic parameters of female rats from normal or small litters

2016 ◽  
Vol 103 (2) ◽  
pp. 169-182
Author(s):  
GM Sakakima ◽  
ER dos Santos ◽  
GC Bueno ◽  
MS Rempel ◽  
JP Furlan ◽  
...  
2021 ◽  
pp. 097275312110057
Author(s):  
Archana Gaur ◽  
G.K. Pal ◽  
Pravati Pal

Background: Obesity is because of excessive fat accumulation that affects health adversely in the form of various diseases such as diabetes, hypertension, cardiovascular diseases, and many other disorders. Our Indian diet is rich in carbohydrates, and hence the sucrose-induced obesity is an apt model to mimic this. Ventromedial hypothalamus (VMH) is linked to the regulation of food intake in animals as well as humans. Purpose: To understand the role of VMHin sucrose-induced obesity on metabolic parameters. Methods: A total of 24 adult rats were made obese by feeding them on a 32% sucrose solution for 10 weeks. The VMH nucleus was ablated in the experimental group and sham lesions were made in the control group. Food intake, body weight, and biochemical parameters were compared before and after the lesion. Results: Male rats had a significant weight gain along with hyperphagia, whereas female rats did not have a significant weight gain inspite of hyperphagia. Insulin resistance and dyslipidemia were seen in both the experimental and control groups. Conclusion: A sucrose diet produces obesity which is similar to the metabolic syndrome with insulin resistance and dyslipidemia, and a VMH lesion further exaggerates it. Males are more prone to this exaggeration.


Author(s):  
Kalyani Sridharan ◽  
Shipra Rachna Singh ◽  
Kripa Elizabeth Cherian ◽  
Nitin Kapoor ◽  
Jane Elizabeth ◽  
...  

2016 ◽  
Vol 8 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Yasuyuki Iwahashi ◽  
Sachie Hirose ◽  
Shinsuke Nakajima ◽  
Akane Seo ◽  
Tetsuya Takahashi ◽  
...  

2010 ◽  
pp. P1-428-P1-428
Author(s):  
J Lo ◽  
S Abbara ◽  
JA Rocha-Filho ◽  
L Shturman ◽  
J Wei ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Xiaohui Guo ◽  
Yifan Xu ◽  
Hairong He ◽  
Hao Cai ◽  
Jianfen Zhang ◽  
...  

Meal replacement plans are effective tools for weight loss and improvement of various clinical characteristics but not sustainable due to the severe energy restriction. The aim of the study was to evaluate the impact of meal replacement, specifically 388 kcal in total energy, on body composition and metabolic parameters in individuals with overweight and obesity from a Chinese population. A parallel, randomized controlled trial was performed with 174 participants (ChiCTR-OOC-17012000). The intervention group (N=86) was provided with a dinner meal replacement, and the control group (N=88) continued their routine diet as before. Body composition and blood parameters were assessed at 0, 4, 8, and 12 weeks. A post hoc analysis (least significant difference (LSD) test), repeated measurements, and pairedT-test were used to compare each variable within and between groups. Significant (p<0.001) improvements in body composition components were observed among the intervention group, including body weight (−4.3 ± 3.3%), body mass index (−4.3 ± 3.3%), waist circumference (−4.3 ± 4.4%), fat-free mass (−1.8 ± 2.9%), and body fat mass (−5.3 ± 8.8%). Body composition improvements corresponded with significant metabolic improvements of blood glucose (−4.7 ± 9.8%). Further improvements in visceral fat area (−7.7 ± 10.1%), accompanying with improvements in systolic (−3.7 ± 6.9%) and diastolic (−5.3 ± 7.7%) blood pressure, were only found in male subjects. To conclude, meal replacement intake with 388 kcal in total energy at dinner time for 12 weeks contributed to improvement in body composition and clinically significant metabolic parameters in both male and female participants with overweight/obesity. Additionally, glucose and blood pressure reduction were gender-specific highlighting the importance of gender stratification for design of nutritional intervention studies for improvement of health.


2020 ◽  
pp. 1-32
Author(s):  
Fatemeh Hajizadeh-Sharafabad ◽  
Ali Tarighat-Esfanjani ◽  
Zohreh Ghoreishi ◽  
Mehrnoosh Sarreshtedari

Abstract Lutein is considered as a major biologically active carotenoid, with potential benefits for obesity and cardiometabolic health. This double-blind, randomized controlled trial aimed to assess whether the consumption of lutein along with a low calorie diet (LCD) can influence anthropometric indices, body composition, and metabolic parameters in obese middle-aged individuals. After a 2-week run-in period with an LCD, 48 participants aged 45–65 y were randomly assigned to consume 20 mg/d lutein or placebo along with LCD for 10 weeks. Dietary intake, anthropometric indices, body composition, lipid profile, glucose homeostasis parameters, non-esterified fatty acids (NEFAs), and appetite sensations were assessed at the beginning and end of the study. After 10 weeks, body weight, and waist circumference significantly decreased in both groups, although between-group differences were not significant. There was a more decrease in the percentage of body fat in the lutein group vs. the placebo group. Moreover, the placebo group experienced a significant reduction in fat free mass (FFM), whereas lutein group preserved FFM during calorie restriction, although between-group difference did not reach statistical significance. Visceral fat and serum levels of total cholesterol (TC) and low-density lipoprotein-cholesterol were significantly decreased only in the lutein group, with a statistically significant difference between two arms only for TC. No significant changes were observed in the triglyceride, high-density lipoprotein-cholesterol, glucose homeostasis parameters, NEFAs, and appetite sensations. Lutein supplementation in combination with an LCD could improve body composition and lipid profile in obese middle-aged individuals.


Bone ◽  
2004 ◽  
Vol 34 (1) ◽  
pp. 180-186 ◽  
Author(s):  
Mia J.T Engelbregt ◽  
Mirjam M van Weissenbruch ◽  
Paul Lips ◽  
Arthur van Lingen ◽  
Jan C Roos ◽  
...  

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