scholarly journals Low dose Spinal Anaesthesia for Cesarean Section in Gravida with Rheumatic Heart Disease

2018 ◽  
Vol 2 (2) ◽  
pp. 25
Author(s):  
TjokordaGde Agung Senapathi ◽  
IGede Budiarta ◽  
MiraKusuma Astuti
Keyword(s):  
Heart Disease ◽  
Cesarean Section ◽  
Rheumatic Heart Disease ◽  
Spinal Anaesthesia ◽  
Low Dose ◽  
Rheumatic Heart

scholarly journals Anaesthetic Management of a Case of Pregnancy with Rheumatic Heart Disease

2021 ◽  
Vol 6 (3) ◽  
pp. 278-280
Author(s):  
Shallu Chaudhary ◽  
Neha Atwal
Keyword(s):  
Heart Disease ◽  
Case Report ◽  
Rheumatic Heart Disease ◽  
Mitral Stenosis ◽  
Intraoperative Monitoring ◽  
Low Dose ◽  
Anaesthetic Management ◽  
Emergency Caesarean Section ◽  
Intravenous Fluids ◽  
Rheumatic Heart

We present a case report of a 28 year old pregnant female with moderate mitral stenosis who was posted for emergency caesarean section. The patient was given low dose subarachnoid block with injection bupivacaine (H) 7.5 mg and injection fentanyl 20 micrograms. Adequate intraoperative monitoring, optimum sedation, analgesia, oxygenation was done. Judicious use of intravenous fluids was considered. The patient maintained smooth intraoperative vitals. Postoperatively also the patient was monitored in the ICU and adequate analgesia was provided. Keywords: Rheumatic Heart Disease, Anaesthetic Management, Pregnancy, Mitral stenosis of rheumatic origin

The polymorphism at the microRNA-155 binding site in AGTR1 gene is not significantly associated with rheumatic heart disease in Saudi Arabia population

MicroRNA ◽  
2020 ◽  
Vol 09 ◽  
Author(s):  
S. Justin Carlus ◽  
Fiona Hannah Carlus ◽  
Mazen Khalid Al-Harbi ◽  
Abdulhadi H Al-Mazroea ◽  
Khalid M Al- Harbi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
Clinical Features ◽  
Left Ventricular ◽  
Genotype Distribution ◽  
Allelic Discrimination ◽  
Children And Young Adults ◽  
And Control ◽  
Rheumatic Heart

Background: Rheumatic heart disease (RHD) remains a major cause of cardiovascular diseases and the most devastating effects are on children and young adults. RHD is caused due to the interaction between microbial, environmental, immunologic, and genetic factors. The renin-angiotensin aldosterone system (RAAS) has been strongly implicated as the susceptibility pathway in the pathogenesis of cardiovascular disease. Objective: The present study investigated the modulating effect of Angiotensin II type 1 receptor (AGTR1) 1166A>C polymorphism on the RHD and its clinical features in Saudi Arabia. Methods: AGTR1 1166A>C polymorphism was genotyped in 96 echocardiographically confirmed RHD patients and 142 ethnically matched controls by TaqMan allelic discrimination method. Results: Genotype distribution of the AGTR1 1166A>C polymorphism was not significantly different between RHD and control groups. Further, AGTR1 1166A>C genotypes are not associated with the clinical features of RHD. These data support that there was no evidence for an association between AGTR1 1166A>C polymorphism and RHD in Saudi Arabia. Conclusion: To our knowledge, this is the first study that has investigated the possible association between AGTR1 1166A>C polymorphism and susceptibility to RHD and its clinical features. Even though AGTR1 gene is 1166A>C (rs5186) was reported to be associated with hypertension, left ventricular hypertrophy and coronary heart disease. Present study did not find any association between AGTR1 1166A>C polymorphism and RHD in Saudi Arabia. Further studies are needed to confirm our findings.

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