scholarly journals Risk factors for hepatitis B virus infections among pregnant women in East Lombok District

2018 ◽  
Vol 6 (2) ◽  
pp. 108
Author(s):  
Eka Faizaturrahmi ◽  
Luh Seri Ani ◽  
Komang Ayu Kartika Sari
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Family Income ◽  
Significant Risk ◽  
World Health ◽  
Hepatitis B Infection ◽  
First Marriage ◽  
History Of

Background and objectives: The World Health Organization has set a target of 90% reduction in new Hepatitis B infections by 2030. The program includes prevention of new infections, and increases testing uptake and treatment. In order to effectively foster prevention, it is necessary to understand the risk factors for transmission. This study aims to determine the risk factors of Hepatitis B infection in pregnant women.Method: A case control study was carried out among 52 pregnant women with HBsAg (+) as cases and 104 pregnant women with HBsAg (-) as controls. The source of cases and controls was the register of pregnant women at the Pringgasela Public Health Center from January 2016 to October 2017. Cases were selected using systematic random sampling from 67 HBsAg (+) pregnant women and controls were selected in the same way from 1644 pregnant women with HBsAg (-). Cases and controls were matched by domicile. The data collected were age, age of first marriage, education, family income, parity, history of miscarriage, maternal or husband’s history of working abroad, frequency of marriage, history of injection, surgery, blood transfusion and dental care. Data collection was carried out with a pre-tested questionnaire in April-May 2018 through interviews at the home of each respondent. Multivariate analysis with logistic regression was carried out to determine the adjusted odds ratio of each risk factor.Results: Case and control characteristics were found to be similar in terms of age, domicile, education and income. Significant risk factors were the history of husband working abroad (AOR=4,115; 95%CI: 1,657-11,075), age of first marriage <20 years (AOR=2,420; 95%CI: 1,157-5,481) and frequency of husband's marriage more than one time (AOR=3,081; 95%CI: 1,345-7,080).Conclusion: Husbands with history of working abroad, age of first marriage <20 years and frequency of husband's marriage more than one time were found to be the risk factors for Hepatitis B infection in pregnant women. These factors require public health attention in order to reduce the transmission of Hepatitis B.

scholarly journals Hepatitis B and C viruses’ infection and associated factors among pregnant women in the Amhara region, Ethiopia: implications for prevention of vertical transmission.

2020 ◽  
Author(s):  
Mulat Dagnew ◽  
Yihenew Million ◽  
Mucheye Gizachew ◽  
Setegn Eshetie ◽  
Gashaw Yitayew ◽  
...  
Keyword(s):  
Public Health ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Associated Factors ◽  
Sub Saharan Africa ◽  
World Health ◽  
Amhara Region ◽  
History Of

Abstract Background Hepatitis virus infection is a major public health burden and silent killer disease in sub-Saharan Africa, including Ethiopia. Despite the recommendations of the World Health Organization, screening for hepatitis B virus (HBV) and hepatitis C virus (HCV) in pregnant women is not done routinely in public health institutions. Therefore, this study aimed to determine the burden of HBV and HCV and its associated factors among pregnant women in the Amhara region, Ethiopia. Methods A total of 1121 pregnant women were enrolled in the study. Data on sociodemographic and associated factors were collected using a structured questionnaire. Blood was collected from the pregnant women, and serum samples were tested for HBsAg and anti-hepatitis C virus antibody (anti-HCV) using ELISA. The status of HIV-infected pregnant women was collected from the records of their charts. SPSS version 20 was used for data analysis, and a binary logistic regression model was used to assess the relationship between factors associated with HBV and HCV infection. Results The seroprevalence of HBsAg and anti-HCV antibody were 4.6% and 1.6, respectively. The co-infection rate of HBV/HCV was 1.4% (1/69). Ten out of 52 HBV positive cases (19.2%) were co-infected with HIV. Only 20 (1.8%) pregnant women had the HBV vaccine. Interestingly, pregnant women with a history of multiple sexual partners (AOR = 3.2,95% CI,1.7–7.6), blood transfusion (AOR = 7.6,95% CI,2.9–16.9), family history of HBV (AOR = 3.5, 95% CI,1.7–7.6), being HIV-positive (AOR = 2.5, 95% CI,1-5.9), and tattooing (AOR = 2, 95% CI, 1-3.8) were significant predictors of HBV infection. Conclusions HBV and HCV infections were intermediate among pregnant women; risk factors were responsible for the majority of cases. Infants born from these infected mothers are at risk of infection. This calls for integration of HBV prevention into the PMTC of HIV. Thus, the provision of health education on HBV and HCV transmission, vaccination, and screening of all pregnant women routinely is essential for PMTCT.

scholarly journals RISK FACTORS;

2009 ◽  
Vol 16 (04) ◽  
pp. 518-525
Author(s):  
SHAHNAZ ANWER ◽  
MUHAMMAD YOUNIS KHAN ◽  
SHEIKH ATIQ-UR- REHMAN
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Dental Treatment ◽  
Significant Risk ◽  
Carrier State ◽  
Carrier Status ◽  
Cross Sectional ◽  
History Of

O b j e c t i v e : To determine the risk factors associated with hepatitis B and C carriers versus healthy pregnant women. Materiala n d M e t h o d s : It was a single center based, cross sectional comparative study, conducted at Gynae ward II, B-V hospital Bahawalpur. Durationof study was from March to August 2008.100 patients were enrolled in the two groups, 50 HbsAg/Anti HCV positive women (cases) to comparewith 50 healthy women (controls) match for parity. The data were recorded on a proforma. R e s u l t s : 100 pregnant women were enrolled. Sixtyeight (68.0%) were aged 25 years or less with a mean age ± S.D of 24.62 ± 3.40. Ten (20%) women had HBV and 40(80%) were HCV positive.The risk factors were compared between the two groups by uni-variate and multivariate analysis which showed that history of dental treatment,blood transfusion, surgery, parenteral treatment and jaundice were significant risk factors for hepatitis B and C carrier status. C o n c l u s i o n :There appears to be a strong co-relation of history of blood transfusion and dental treatment with HbsAg/ Anti HCV carrier state in pregnantwomen. The anti HCV seropositivity was appreciably high (80%) as compared to HbsAg (20%) in carrier pregnant women.

scholarly journals Surveillance of Hepatitis B Biomarkers in Borno State, Nigeria

2019 ◽  
pp. 1-8
Author(s):  
S. O. Oyinloye ◽  
D. N. Bukbuk ◽  
F. A. Sanda
Keyword(s):  
Public Health ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Blood Donor ◽  
Civil Servant ◽  
Civil Servants ◽  
World Health ◽  
Hepatitis B Infection ◽  
B Virus

Background: Hepatitis B virus infection is a major global health problem of public health importance. The World Health Organization (WHO) African Region has reported an approximately 100 million people with chronic hepatitis B virus (HBV) infection and Nigeria has been classified as endemic. Objectives: The objectives of this study were to determine (i) the prevalence of hepatitis B infection (ii) the immune status to hepatitis B among patients (iii) the susceptibility rate. Methods: A total of four hundred and ten (410) sera were collected at random from patients attending various hospitals in Borno state. A self-structured questionnaire was used to obtained demographic data which included age and sex, social status (e.g. trader, farmer, civil servant or student), pregnancy status, blood donor type. Sera samples were obtained for qualitative detection of HBsAg using rapid chromatographic immunoassays with test kits from Qingdao Hightop Biotech Co., China having sensitivity, specificity and accuracy of 99%, 97% and 98.5% respectively. Results: This is a first-phase result of a surveillance of hepatitis B biomarkers in Borno state Nigeria. The proportion of male (248:60.5%) was higher than female (162:39.5%). Out of the 410 samples assayed, overall prevalence of 7.1%, 2%, 0%, 47.1% and 45.6% for HBsAg (Hepatitis B surface antigen), HBsAb (anti-HBs), HBeAg (Hepatitis B envelop antigen), HBeAb (Anti-HBe) and HBcAb (Anti-HBcore) respectively were obtained. A total of 24.1% (7/29) of the HBsAg positives were negative for all other biomarkers suggesting new cases in the acute phase. The later comprise of 2 pregnant women, 1 blood donor, 3 farmers and 1 civil servant. Sixteen (3.9%) of the 410 samples were negative for all the biomarkers. Of these, 11(68.8%) were pregnant women, 1 private blood donor and 2 students and 2 civil servants. Gender-based prevalence of HBsAg among male was 8.5% (21/248) and 4.9% (8/162) among female. Out of 29/410 (7.1%) HBsAg positives, 89.7% (26/29) were between 15–34 years old. Out of 150 blood donors, the prevalence of HBsAg was 8.7% (13/150) while among 50 pregnant women it was 8% (4/50). HBsAg positivity proportion was (10/29) among students; civil servants (7/29); traders (6/29) and farmers (6/29). Conclusion: Hepatitis B infection continues to be a public health hazard due to existence of susceptible individuals and emerging new cases as observed in this study. Therefore, routine vaccinations at all levels should be invigorated while continuous surveillance of the infection is maintained until population immunity can be achieved.

scholarly journals Seroprevalence of hepatitis B surface antigen and associated risk factors among pregnant women

2018 ◽  
Vol 12 (10) ◽  
pp. 904-909 ◽  
Author(s):  
Sirin Cetin ◽  
Meryem Cetin ◽  
Ebru Turhan ◽  
Kenan Dolapcioglu
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
Multivariate Logistic Regression Analysis ◽  
Hbv Infection ◽  
Factors Associated ◽  
History Of

Introduction: Hepatitis B infection is a serious global public health problem. The aim of the study was to assess the seroprevalance of hepatitis B surface antigen (HBsAg), as well as the risk factors associated with hepatitis B virus (HBV) infection among pregnant women attending antenatal care clinics of the University Hospital in Antioch, Turkey. Methodology: This descriptive cross-sectional study was carried out between May 2016 and December 2016. The Chi-squared was utilized to estimate the statistical significance of the association between socio-demographic variables and HBsAg status. The results were generated as proportions odds ratio (OR) with their 95% confidence intervals (Cl) and calculated by using both univariate and multivariate logistic regression analysis. Results: The seroprevalence of HBsAg was found to be 2.1%. A significant association was observed between age and HBsAg seropositivity (p = 0.027). History of blood transfusion (AOR = 9.51, 95% CI = 1.92-46.80, p = 0.006), history of hepatitis (AOR = 11.13, 95% CI = 2.02-61.28, p = 0.006), tattooing (AOR = 13.64, 95% CI = 2.52-73.76, p = 0.002) and a history of household/close contact (AOR = 11.10, 95% CI = 1.56-78.65, p = 0.016) were significantly associated with the risk of HBV infection. Conclusions: Data regarding the seroprevalence of HBsAg and risk factors associated with HBV infection in pregnant women plays a crucial role in evaluating the effectiveness of the public health protection policies and the strategies to control the disease.

Papillomaviral infection and cervical diseases in pregnant women. Risk factors of social status, reproductive and contraceptive behavior

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (6) ◽  
pp. 74-79
Author(s):  
Tamara N. Bebneva ◽  
Galina B. Dikke
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Social Status ◽  
Significant Risk ◽  
Hpv Infection ◽  
Low Risk ◽  
Contraceptive Behavior ◽  
Regular Screening ◽  
History Of ◽  
Cervical Diseases

Aim. To determine the risk factors for human papillomavirus of high carcinogenic risk (HPV HCR) and cervical diseases (CD) in pregnant women associated with the social status, reproductive and contraceptive behavior. Materials and methods. Design: open-label comparative non-interventional cohort study in parallel groups. The total number of patients 330 people, of whom 148 women were negative for HPV and 182 women were positive. They were divided into 4 groups depending on the presence or absence of CD. Methods: analysis of anamnesis data, general clinical, test Kvant-21 to determine HPV, cytological examination, extended colposcopy. Results. The most significant risk factors for HPV HRS infection were identified: history of mycoplasma infection (OR 5.9) and BV (OR 5.3), alcohol consumption (OR 4.0). A history of STIs (trichomoniasis and chlamydial infection), as well as more than 3 sexual partners (OR 2.7) were also significant. The most significant risk factors for CD in HPV-infected women were: age over 35 years (OR 3.8), a history of bacterial vaginosis (OR 3.0), and lack of regular screening (OR 2.4). The coitarche earlier than 16 years old (OR 2.2) also mattered. There were also found factors indicating a low risk of HPV infection the use of condoms (OR 0.3), and a low risk of CD was indicated by age under 25 years (OR 0.2) and regular screening (OR 0.3). Conclusion. HPV infection with HRS and the prevalence of CMC in pregnant women against the background of HPV infection is associated mainly with social risk factors, to a lesser extent with factors of reproductive and contraceptive behavior.

scholarly journals Prevalence and risk factors of hepatitis b infection in HIV infected children seen at national hospital Abuja

2021 ◽  
Vol 48 (2) ◽  
pp. 62-65
Author(s):  
O.A. Adeoye ◽  
O. Oniyangi ◽  
I.A. Ojuawo
Keyword(s):  
Risk Factors ◽  
Hepatitis B ◽  
Hepatitis B Surface Antigen ◽  
Significant Risk ◽  
Hepatitis B Vaccination ◽  
Rapid Progression ◽  
Hepatitis B Infection ◽  
National Hospital ◽  
Blood Samples ◽  
Paediatric Hiv

Background: Human immunodeficiency virus infection remains a global pandemic. Co infection with hepatitis B virus leads to rapid progression to AIDS if not diagnosed and promptly treated or better still prevented. The study aims at determining the prevalence and risk factors of hepatitis B infection in HIV infected children being followed up at the Paediatric HIV clinic. Patients and methods: A cross-sectional study of 261 HIV infected children aged eight months to fourteen years to determine the prevalence of Hepatitis B infection and pattern of hepatitis B vaccination was carried out between July and October 2012 at the Paediatric HIV clinic of National Hospital Abuja. Ethical approval was obtained from Ethical Committee of the hospital. Vaccination and transfusion history were obtained from the parents and guardians of the subjects using a proforma after signed informed consent. Blood samples were collected for Hepatitis B surface antigen screening and Hepatitis B screening in those with HBsAg positive blood samples. Results: Only 3 (1.15%) of the 261 HIV infected children had Hepatitis B infection. All the children less than 5 years old in this cohort received hepatitis B vaccination and none of them had Hepatitis B infection. The HIV/HBV co infected children were older than ten years (p = 0.047) and history of blood transfusion (p = 0.003) was also significant. However, scarification (p = 0.996), local circumcision (p = 0.928); uvulectomy (p = 0.898) were not significant risk factors in this cohort. Conclusion: There is need to intensify routine hepatitis B vaccination and routine screening of blood before necessary transfusion. This would further lead to a low prevalence of Hepatitis B in HIV infected children and the general populace at large.

scholarly journals Risk factor of severe preeclampsia in Dr. Soetomo Hospital Surabaya in 2015

2018 ◽  
Vol 25 (1) ◽  
pp. 6 ◽  
Author(s):  
Amelia Rahmah Kartika ◽  
Muhammad Ilham Aldika Akbar ◽  
Pirlina Umiastuti
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Pregnant Women ◽  
Medical Records ◽  
Maternal Obesity ◽  
Significant Risk ◽  
Severe Preeclampsia ◽  
History Of

Objectives: to determine which of the risk factors above associated with the occurrence of severe preeclampsia at dr. Soetomo Hospital, Surabaya during 2015.Materials and Methods: The type and design of the study were analytic and retrospective. This study was held in the dr. Soetomo Hospital from April until November 2016. The instrument of the study was the medical records then being coded and analysed. The samples were 134 pregnant women, consisting of 67 pregnant women with severe preeclampsia as cases and 67 pregnant women as controls.Results: Maternal obesity (OR= 5,786; 95% CI: 2,300–14,555), history of hypertension (OR= 6,693; 95% CI: 1,848–24,237) and secondary elderly primi (OR= 6,384; 95% CI: 1,357–30,031) are associated with the development of severe preeclampsia.Conclusion: In conclusion, the significant risk factors of severe preeclampsia in dr. Soetomo Hospital Surabaya during 2015 are obesity, history of hypertension and secondary elderly primi variables.

Prevalence of some hepatitis B virus markers among pregnant women attending antenatal clinic in Specialist Hospital Sokoto Nigeria

2020 ◽  
Vol 28 (3) ◽  
pp. 233-243
Author(s):  
O. Erhabor ◽  
S.Y. Mohammad ◽  
L. Bello ◽  
F.U. Onuigwe ◽  
Y. Abdulrahman ◽  
...  
Keyword(s):  
Public Health ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Previous History ◽  
Public Health Problem ◽  
Antenatal Clinic ◽  
B Virus ◽  
History Of ◽  
Hepatitis B Virus Markers

BACKGROUND: Hepatitis B virus infection is a global public health problem. The virus has infected more than one-third of the global population. It has been estimated that 360 million chronic carriers are living around the world with a high risk for developing cirrhosis, hepatic carcinoma and hepatic failure. OBJECTIVE: The aim of this study was to determine the prevalence of some hepatitis B markers among pregnant women attending antenatal clinic in Sokoto Specialist Hospital, Nigeria. METHODS: The hepatitis testing was carried out using the Skytec-Rapid Diagnostic HBV-5 rapid kit (Skytec-Rapid Diagnostic, USA). The kit is based on lateral flow chromatographic immunoassay for the qualitative detection of HBsAg, HBsAb, HBeAg, HBeAb, and HBcAb in human serum or plasma. Panel format can conveniently test for five targets at once and utilizes all markers to help distinguish between acute and chronic infections. RESULTS: Out of 117 pregnant women tested, 15 were positive for HBsAg (12.8%), 6 positive for HBsAb (5.1%), 1 for HBeAg (0.9%), 14 tested positive for HBeAb (12.0%), and 14 tested for HBcAb (12.0%). The prevalence of HBsAg, HBsAb, HBeAg, HBcAb and HBcAb was compared based on ethnicity. HBsAb was significantly higher among the Hausa ethnic group (p= 0.001). The prevalence of HBsAb, HBeAg, HBcAb and HBcAb was not affected by ethnicity (p> 0.05). The prevalence of HBsAg, HBsAb, HBeAg, HBcAb and HBcAb was compared based on age. Infection by the hepatitis B virus markers was higher among young adult and middle age groups. The difference was however not statistically significant (p> 0.05). The prevalence of HBsAg, HBsAb, HBeAg, HBcAb and HBcAb was compared based on the educational status, previous history of blood transfusion, jaundice, employment status and previous history of still births among the pregnant subjects. There were no statistically significant differences in the prevalence of Hepatitis B virus markers (p> 0.05). CONCLUSION: The study observed a high prevalence of various hepatitis B viral markers among pregnant women attending antenatal care in Specialist Hospital Sokoto. There is need for routine screening of all pregnant women and infants born to hepatitis B positive mothers. Government and non-governmental organizations should intensify efforts to enlighten the general population on the public health importance of the disease and the importance of hepatitis screening. There is also need for the development of a treatment protocol for the management of pregnant women positive for hepatitis B to prevent mother to child transmission. There is an urgent need for the implementation of evidenced-based best practice of providing universal vaccination against hepatitis B for all hepatitis B negative women of child bearing age in particular and all Nigerians in general.

scholarly journals Seroepidemiology and associated risk factors of hepatitis B and C virus infections among pregnant women attending maternity wards at two hospitals in Swabi, Khyber Pakhtunkhwa, Pakistan

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255189
Author(s):  
Muhammad Israr ◽  
Fawad Ali ◽  
Arif Nawaz ◽  
Muhammad Idrees ◽  
Aishma Khattak ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Vertical Transmission ◽  
Educational Level ◽  
Khyber Pakhtunkhwa ◽  
History Of ◽  
Associated Risk Factors ◽  
Pregnant Mothers

Background & aim Hepatitis B and C infections are global issues that are associated with a massive financial burden in developing countries where vertical transmission is the major mode and remains high. This cross-sectional study was designed to investigate the seroepidemiology and associated risk factors of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among 375 pregnant women attending antenatal care health facilities at Bacha Khan Medical Complex (BKMC) Shahmansoor and District Head Quarter (DHQ) Hospital Swabi, Khyber Pakhtunkhwa, Pakistan. Methodology From a total of 375 pregnant women selected using systematic random sampling from both hospitals, 10 ml of blood samples were collected and alienated serum was examined for indicators identification through the Immuno-Chromatographic Test (ICT) and 3rd Generation Enzyme-Linked Immunosorbent Assay (ELISA). A pre-structured questionnaire was used to collect the socio-demographic data and possible risk factors. The data was analyzed via SPSS 23.0 statistical software. A chi-square analysis was performed to determine the association between variables. P-value < 0.05 was set statistically significant. Results The overall frequency of HBV and HCV among 375 pregnant women involved in the study was 3.7% and 2.1% respectively. None of the pregnant women were co-infected with HBV and HCV. Dental extraction (P = 0.001) and blood transfusion (P = 0.0005) were significantly allied with HBV infection while surgical procedure (P = 0.0001) was significantly associated with HCV infection. Moreover the sociodemographic characteristics: residential status (P = 0.017) and educational level (P = 0.048) were found significant risk factors of HBsAg and maternal age (P = 0.033) of anti-HCV, respectively. Conclusion & recommendation HBV and HCV infections are intermediary endemic in the study area. A higher prevalence of HBV was detected among pregnant mothers with a history of dental extraction, history of blood transfusion, resident to the urban area and low educational level. The age and surgical procedures were the potential risk factors found significantly associated with HCV positivity among pregnant mothers in our setup. Future negotiations to control vertical transmission should include routine antenatal screening for these infections early in pregnancy and the requirement of efficient preventive tools including the birth dose of the hepatitis B vaccine in combination with hepatitis B immune globulins to the neonate.

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