The Use of Superelasticity in Modern Medicine

MRS Bulletin ◽  
2002 ◽  
Vol 27 (2) ◽  
pp. 101-104 ◽  
Author(s):  
T. W. Duerig

AbstractThe value of Nitinol (Ni-Ti) in the field of medicine has proven to be far greater than just as the simple “springy metal” it was once considered to be. In particular, its use in vascular implants highlights many valuable yet subtle behaviors, including a “biased stiffness,” enhanced fatigue resistance, low magnetic susceptibility, and good biocompatibility. Nitinol today is nearly as well known to medical-device designers and physicians as are stainless steel and titanium, and it is the enabling ingredient in a growing number of successful and profitable life-saving devices.

2021 ◽  
Vol 87 ◽  
pp. 39-48
Author(s):  
T. Stanescu ◽  
S.H. Mousavi ◽  
M. Cole ◽  
E. Barberi ◽  
K. Wachowicz

2019 ◽  
Vol 13 (1) ◽  
pp. 57-60
Author(s):  
Damla Özsu Kırıcı ◽  
Ertuğrul Karataş ◽  
Ahmet Demirhan Uygun ◽  
Ezgi Doğanay Yıldız ◽  
Kezban Meltem Çolak ◽  
...  

Background. The aim of the present study was to compare the cyclic fatigue resistance of novel nickel titanium rotary pathfinding instruments. Methods. Twenty instruments were selected for each file system. A simulated stainless steel root canal, with a 90° angle of curvature and a curvature radius of 3 mm, was used for cyclic fatigue test of the ProGlider (#16, progressive taper: 0.02‒ 0.085), PathGlider (#15, taper: .03), and One G (#14, taper: .03) instruments. Statistical analyses were performed with oneway ANOVA (P=0.05). Post hoc Tukey tests were used to determine any statistically significant differences between the groups. Results. The ProGlider instruments exhibited significantly more cyclic fatigue resistance than both PathGlider and One G instruments (P<0.001). One G instruments had significantly more resistance to fracture than PathGlider instruments (P<0.05). Conclusion. ProGlider instruments had better cyclic fatigue resistance than PathGlider and One G instruments.


Antibiotics ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 305
Author(s):  
Ellen Twomey ◽  
Colin Hill ◽  
Des Field ◽  
Maire Begley

Staphylococcus epidermidis is frequently implicated in medical device-related infections. As a result of this, novel approaches for control of this opportunistic pathogen are required. We examined the ability of the natural peptide nisin A, produced by Lactococcus lactis, to inhibit S. epidermidis. In addition, a bank of 29 rationally selected bioengineered L. lactis strains were examined with the aim of identifying a nisin derivative with enhanced antimicrobial activity. Agar-based deferred antagonism assays revealed that wild type nisin A inhibited all 18 S. epidermidis strains tested. Larger zones of inhibition than those obtained from the nisin A producing L. lactis strain were observed for each derivative producer against at least one S. epidermidis strain tested. Six derivative producing strains, (VGA, VGT, SGK, M21A, M17Q, AAA), gave larger zones against all 18 strains compared to the wildtype producing strain. The enhanced bioactivity of M17Q was confirmed using well diffusion, minimum inhibitory concentration (MIC) and a broth-based survival assays. Biofilm assays were performed with plastic microtiter plates and medical device substrates (stainless-steel coupons and three catheter materials). The presence of nisin A significantly reduce the amount of biofilm formed on all surfaces. M17Q was significantly better at reducing biofilm production than nisin A on plastic and stainless-steel. Finally, M17Q was significantly better than nisin A at reducing bacterial numbers in a simulated wound fluid. The findings of this study suggest that nisin and bioengineered derivatives warrant further investigation as potential strategies for the control of S. epidermidis.


Author(s):  
A. Arunmani ◽  
T. Senthilkumar

In engineering industries and heavy manufacturing plants, fatigue life of joints plays a pivotal role in determining the overall life span of the welded joint. In this paper, an advanced fusion joining technique, namely activated tungsten inert gas welding, was used for joining UNS S32750 super duplex stainless steel, with ZnO as activation flux. For the enhancement of fatigue resistance of joints, important welding process parameters were fluctuated according to a developed central composite design model. Empirical relationships were developed between the process parameters and the fatigue strength of the joints, which was correlated with the number of cycles to failure (NCF). Using analysis of variance, the significance of the developed fatigue model was ascertained. Using response surface methodology, optimization of process parameters for enhancement of fatigue resistance was done. It was observed that at the optimized activated tungsten inert gas weld process parameters of travel speed of welding torch at 69.85 mm/min, weld current at 125.20 A, and shielding gas flow rate at 14.77 L/min, a high fatigue life of 7.66396 × 108 NCF was obtained and the model was validated to very high predictability. Microstructural variations in the fatigue-tested specimens were evaluated for identifying the grain modifications.


2004 ◽  
Vol 22 (2) ◽  
pp. 101-114 ◽  
Author(s):  
N. Acuna, ◽  
C. Rosado, ◽  
B. Valdez, ◽  
M. Schorr, ◽  
G. Hernandez-Duque,

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