scholarly journals Percutaneous Cryoablation for Renal Cell Carcinoma

2015 ◽  
Vol 2 (3) ◽  
pp. 105-113 ◽  
Author(s):  
Tsitskari Maria ◽  
Christos Georgiades
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Early Stage ◽  
Imaging Techniques ◽  
Percutaneous Ablation ◽  
Renal Masses ◽  
Cross Sectional ◽  
Percutaneous Cryoablation ◽  
Nephron Sparing

Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults. Nephron sparing resection (partial nephrectomy) has been the “gold standard” for the treatment of resectable disease. With the widespread use of cross sectional imaging techniques, more cases of renal cell cancers are detected at an early stage, i.e. stage 1A or 1B.  This has provided an impetus for expanding the nephron sparing options and especially, percutaneous ablative techniques.  Percutaneous ablation for RCC is now performed as a standard therapeutic nephron-sparing option in patients who are poor candidates for resection or when there is a need to preserve renal function due to comorbid conditions, multiple renal cell carcinomas, and/or heritable renal cancer syndromes. During the last few years, percutaneous cryoablation has been gaining acceptance as a curative treatment option for small renal cancers. Clinical studies to date indicate that cryoablation is a safe and effective therapeutic method with acceptable short and long term outcomes and with a low risk, in the appropriate setting.  In addition it seems to offer some advantages over radio frequency ablation (RFA) and other thermal ablation techniques for renal masses.

scholarly journals Minimal Invasive Treatments for Renal Cell Carcinoma

2020 ◽  
pp. 1-8
Author(s):  
Selahattin Çalışkan ◽  
Mustafa Sungur
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Fruits And Vegetables ◽  
Imaging Techniques ◽  
Locally Advanced ◽  
Minimal Invasive ◽  
Renal Tumors ◽  
Renal Masses ◽  
Magnetic Resonance Imaging Techniques

Renal cell carcinoma (RCC) is the most common malignancy of the kidney that accounts 85% of all renal tumors and 2-3% of all adult malignancies . The etiology of RCC associated with smoking , obesity, anti-hypertensive therapy, coffee and tea, Western diet (high fat and protein and low fruits and vegetables). However, the detection of small renal masses has been increased because of widespread use of sonography, computed tomography and magnetic resonance imaging techniques in recent years, but one-third of the patients with RCC still present with large, locally advanced or metastatic disease. Surgery is the main treatment for renal cell carcinoma and minimal invasive treatments such as laproscopy and robotic approaches is very popular in the world after the widespread use of technological instruments and technology.

scholarly journals Correlation between radiological and histopathological findings in patients undergoing nephrectomy for presumed renal cell carcinoma on computed tomography scan at Grey’s Hospital

2018 ◽  
Vol 22 (1) ◽  
Author(s):  
Nompumelelo E. Mlambo ◽  
Nondumiso N.M. Dlamini ◽  
Ronald J. Urry
Keyword(s):  
Computed Tomography ◽  
Renal Cell Carcinoma ◽  
Ct Scan ◽  
Cell Carcinoma ◽  
South African ◽  
Renal Cell ◽  
Vascular Invasion ◽  
Retrospective Chart Review ◽  
Renal Masses ◽  
Cross Sectional

Background: The incidence of renal cell carcinoma (RCC) is increasing globally owing to the increased use of cross-sectional imaging. Computed tomography (CT) scan is the modality of choice in the diagnosis and pre-operative assessment of RCC. Nephrectomy is the standard treatment for RCC and pre-surgery biopsy is not routinely practised. The accuracy of CT diagnosis and staging in a South African population has not been established.Objectives: To determine the accuracy of CT scan in the diagnosis and pre-operative staging of RCC at Grey’s Hospital.Methods: A retrospective chart review was performed; CT scan reports and histopathological results of adult patients who underwent nephrectomy for presumed RCC on CT scan between January 2010 and December 2016 were compared.Results: Fifty patients met the inclusion criteria for the study. CT significantly overestimated the size of renal masses by 0.7 cm (p = 0.045) on average. The positive predictive value of CT for RCC was 81%. Cystic tumours and those 4 cm and smaller were more likely to be benign. CT demonstrated good specificity for extra-renal extension, vascular invasion and lymph node involvement, but poor sensitivity.Conclusion: In our South African study population, CT is accurate at diagnosing RCC, but false-positives do occur. Non-enhancing or poorly enhancing, cystic, fat-containing and small lesions (4 cm or smaller) are more likely to be benign and ultrasound-guided biopsy should be considered to avoid unnecessary surgery. CT assessment of extra-renal extension and vascular invasion is challenging and additional imaging modalities such as magnetic resonance imaging (MRI) venogram, duplex Doppler ultrasound or Positron emission tomography–computed tomography (PET/CT) may be beneficial.

scholarly journals Systematic Review of Contemporary Evidence for the Management of T1 Renal Cell Carcinoma: What IRs Need to Know for Kidney Cancer Tumor Boards

2019 ◽  
Vol 36 (03) ◽  
pp. 194-202 ◽  
Author(s):  
Julie Cronan ◽  
Sean Dariushnia ◽  
Zachary Bercu ◽  
Robert Mitchell Ermentrout ◽  
Bill Majdalany ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Early Stage ◽  
The United States ◽  
Cross Sectional ◽  
Increased Risk ◽  
Tumor Boards ◽  
Cancer Tumor ◽  
Cross Sectional Imaging

AbstractRenal cell carcinoma is a relatively common malignancy, with 60 to 70 thousand cases a year in the United States alone. Increased utilization of cross-sectional imaging has led to an increase in the number of early renal cell cancers seen by the medical establishment. In addition, certain patient populations have an increased risk of developing kidney cancers which may mandate aggressive screening protocols. This article discusses the epidemiology of renal cell cancers; discusses the current management guidelines from multiple specialty societies; discusses some of the surgical and interventional techniques used in the treatment of such lesions; and provides a review of the literature regarding treatments of early-stage renal cell cancers.

Incidence of benign versus malignant renal tumors in selected studies.

2012 ◽  
Vol 30 (5_suppl) ◽  
pp. 357-357 ◽  
Author(s):  
Paul Russo ◽  
Robert G. Uzzo ◽  
William Thomas Lowrance ◽  
Aviva Asnis-Alibozek ◽  
Norman David LaFrance ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Malignant Tumors ◽  
Early Stage ◽  
Renal Tumors ◽  
Benign Tumors ◽  
Stage Migration ◽  
Renal Masses ◽  
Definitive Method

357 Background: Use of cross-sectional imaging has increased the detection rate for small renal tumors; more patients now present with early-stage renal cell carcinoma (RCC) or benign or indolent renal masses. Histopathology after surgical resection is the definitive method for characterizing renal tumors. Stage migration of renal masses creates uncertainty about the percentage of resected masses that will be benign vs malignant. We sought to better define these proportions through a targeted review of the literature. Methods: PubMed/select congresses were searched to identify the histologic classification of renal masses in a representative sample from the contemporary literature: [search] incidence AND (renal cell carcinoma AND benign); incidence AND (renal tumor AND benign); percentage AND (renal cell carcinoma AND benign); limit: 2003–2011. Results: Most representative studies included procedures conducted in the mid-1990s to the mid-to-late 2000s. Studies origin was US (n=8), Korea (n=3), China, Japan, Germany, Austria, Australia, and multisite (Israel/France/US; all n=1). Only 8 studies had n≥500 (range, 70–10,404). The proportion of benign masses are shown (see Table); half of the studies reported values between 16% and 17%. The majority found that benign tumors were more likely to be smaller in size (<4 or <7 cm) than malignant tumors. 11 studies reported the RCC subtype (% clear cell range, 46%–83%). Conclusions: Benign renal tumors occur ~15% of the time and are more prevalent among small masses. Nearly 25% of resected lesions are benign or indolent and may not require surgery. Preoperative discrimination of more aggressive renal masses would be an important clinical advance that could improve clinicians’ diagnostic confidence and guide patient management. Funding: Wilex AG/IBA Molecular. [Table: see text]

The EORTC Intergroup Phase 3 Study Comparing the Oncological Outcome of Elective Nephron-Sparing Surgery and Radical Nephrectomy for Low-Stage Renal Cell Carcinoma

2021 ◽  
pp. 107-112
Author(s):  
Christopher Weight
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Radical Nephrectomy ◽  
Progression Free Survival ◽  
Oncological Outcome ◽  
Nephron Sparing Surgery ◽  
Renal Masses ◽  
Free Survival ◽  
Nephron Sparing

This chapter summarizes the findings of a notable non-inferiority trial comparing nephron-sparing surgery to radical nephrectomy for small renal masses suspected to be renal cell carcinoma. Overall survival results favored radical nephrectomy and progression-free survival was largely similar. Its findings remain controversial but suggest that the assumed benefits of nephron-sparing surgery over radical nephrectomy based on non-randomized studies may have been overstated and that in many cases both approaches may have similar outcomes.

scholarly journals Pneumodissection during Percutaneous Renal Ablation Resulting in Air Embolism: Percutaneous Management and a Review of the Literature

2019 ◽  
Vol 36 (02) ◽  
pp. 120-125
Author(s):  
Kamil Arif ◽  
Andrew J. Gunn
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Air Embolism ◽  
Percutaneous Ablation ◽  
Review Of The Literature ◽  
Renal Ablation ◽  
Nephron Sparing ◽  
Collecting System ◽  
Urinary Collecting System

AbstractPercutaneous renal ablation is a nephron-sparing approach for selected patients with renal cell carcinoma. Common complications include hemorrhage, injury to the urinary collecting system, and abscess formation. The purpose of this article is to present a case of vascular air embolism as a complication of pneumodissection performed during percutaneous ablation of renal cell carcinoma, discuss its successful percutaneous management, review common complications of renal ablation, and outline steps physicians can take to lessen these complications.

Renal Cell Carcinoma: Alternative Nephron-Sparing Treatment Options for Small Renal Masses, a Systematic Review

2017 ◽  
Vol 31 (10) ◽  
pp. 963-975 ◽  
Author(s):  
Fieke M. Prins ◽  
Linda G.W. Kerkmeijer ◽  
Anne A. Pronk ◽  
Evert-Jan P.A. Vonken ◽  
Richard P. Meijer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Treatment Options ◽  
Small Renal Masses ◽  
Renal Masses ◽  
Nephron Sparing

scholarly journals Magnetic Resonance Imaging as a Biomarker for Renal Cell Carcinoma

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Yan Wu ◽  
Young Suk Kwon ◽  
Mina Labib ◽  
David J. Foran ◽  
Eric A. Singer
Keyword(s):  
Magnetic Resonance Imaging ◽  
Renal Cell Carcinoma ◽  
Magnetic Resonance ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Imaging Techniques ◽  
Computational Imaging ◽  
Resonance Imaging ◽  
Cross Sectional ◽  
Pubmed Search

As the most common neoplasm arising from the kidney, renal cell carcinoma (RCC) continues to have a significant impact on global health. Conventional cross-sectional imaging has always served an important role in the staging of RCC. However, with recent advances in imaging techniques and postprocessing analysis, magnetic resonance imaging (MRI) now has the capability to function as a diagnostic, therapeutic, and prognostic biomarker for RCC. For this narrative literature review, a PubMed search was conducted to collect the most relevant and impactful studies from our perspectives as urologic oncologists, radiologists, and computational imaging specialists. We seek to cover advanced MR imaging and image analysis techniques that may improve the management of patients with small renal mass or metastatic renal cell carcinoma.

scholarly journals Role of Computed Tomography in Evaluation of Renal Masses

2020 ◽  
Vol 11 (3) ◽  
pp. 4024-4031
Author(s):  
Shrishail Adke ◽  
Dinesh Potdar
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Renal Mass ◽  
Early Stage ◽  
Methodological Approach ◽  
Diagnostic Efficiency ◽  
Intravenous Pyelography ◽  
Renal Masses

At present there are various ways to recognize and evaluate kidney mass. A systematic methodological approach is needed to ensure a complete assessment of the suspected kidney mass, because each x-ray modality has relative strengths and weaknesses for an accurate diagnosis. Despite the lack of sensitivity and specificity, intravenous pyelography (IVP) remains the original diagnostic method in many cases because it plays a role in the assessment of hematuria. Intravenous pyelography with or without nephrotomography can detect a lot of kidney mass and provide information about kidney function. As the modality of imaging has expanded extensively, the measurement of adverse renal mass has improved significantly. The heterogeneous development, necrosis or calcification of such a by-of renal cell carcinoma is strongly suggestive. This research describes early-stage accidental renal cell carcinoma as correlated with symptoms of patients with renal cell carcinoma. It has significant implications on therapeutic strategies such as partial nephrectomy, etc. and increases the recovery of premature lesions. It suggests that the renal mass requires monitoring at age over 40 and high-risk classes such as the background of renal cell carcinoma, VHL, etc. The most common and successful modality for the measurement and characterisation of renal weight remains computational multidetector tomography (MDCT). The diagnostic efficiency of RCC in characterising and predicting the severity of disease is vastly enhanced by MDCT scans with an increase in spatial resolution and the potential to provide multiplanar and 3D recreations.

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