Current Evidence on Dental Implants Outcomes in Smokers and Nonsmokers: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 44 (5) ◽  
pp. 390-399 ◽  
Author(s):  
Sara A. Alfadda
Keyword(s):  
Systematic Review ◽  
Bone Loss ◽  
Dental Implants ◽  
Prospective Studies ◽  
Implant Failure ◽  
Current Evidence ◽  
First Year ◽  
Controlled Trials ◽  
Marginal Bone Loss ◽  
Randomized Controlled

This systematic review aims to answer the following PICO (Participants, Intervention, Comparison, and Outcome) question: “Does smoking increase the rates of implant failure and peri-implant marginal bone loss in patients with dental implants?” An extensive electronic search of the Cochrane Central Register of Controlled Trials, PubMed, Medline, Embase, and Web of Science databases and a subsequent hand search were performed. Only randomized controlled trial, controlled clinical trials, and prospective studies published up to January 2017 were included. For dichotomous outcomes, the effect estimates for smoking are expressed as odds ratios and 95% CIs. For continuous outcomes, weighted mean differences (WMDs) and 95% CIs are presented. Three randomized controlled trials and 7 prospective studies were included. The odds ratio for implant failure among smokers was 2.92 (95% CI, 1.76–4.83) (P < .001). First-year marginal bone loss in smokers ranged from 0.02 to 0.45 mm. In the nonsmokers, bone loss ranged from −0.08 to 0.42 mm. Nonsmokers lost significantly less bone during the first year (WMD = 0.11 mm, 95% CI. 0.03–0.19) and subsequent years (WMD = 0.11 mm, 95% CI, 0.03–0.19, P = .009). The available scientific evidence suggests that smoking is associated with significantly increased rates of implant failure and marginal bone loss.

scholarly journals Evaluation of Implant Collar Surfaces for Marginal Bone Loss: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Roodabeh Koodaryan ◽  
Ali Hafezeqoran
Keyword(s):  
Systematic Review ◽  
Bone Loss ◽  
Dental Implants ◽  
Retrospective Studies ◽  
Meta Analysis ◽  
Survival Rates ◽  
Marginal Bone Loss ◽  
Eligibility Criteria ◽  
Randomized Controlled ◽  
Present Systematic Review

Background. It is important to understand the influence of different collar designs on peri-implant marginal bone loss, especially in the critical area.Objectives. The purpose of the present systematic review and meta-analysis was to compare dental implants with different collar surfaces, evaluating marginal bone loss and survival rates of implants.Methods. Eligibility criteria included clinical human studies, randomized controlled trials, and prospective and retrospective studies, which evaluated dental implants with different collar surface in the same study.Results. Twelve articles were included, with a total of 492 machined, 319 rough-surfaced, and 352 rough-surfaced microthreaded neck implants. There was less marginal bone loss at implants with rough-surfaced and rough-surfaced microthreaded neck than at machined-neck implants (difference in means: 0.321, 95% CI: 0.149 to 0.493;p<0.01).Conclusion. Rough and rough-surfaced microthreaded implants are considered a predictable treatment for preserving early marginal bone loss.

scholarly journals Dental Implant Failure Rate and Marginal Bone Loss in Transplanted Patients: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Marcela Paraizo ◽  
João Botelho ◽  
Vanessa Machado ◽  
José João Mendes ◽  
Ricardo Alves ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Loss ◽  
Dental Implants ◽  
Dental Implant ◽  
Failure Rate ◽  
Case Control ◽  
Risk Of Bias ◽  
Implant Failure ◽  
Cochrane Library ◽  
Marginal Bone Loss

This systematic review investigates the failure rate and marginal bone loss (MBL) of dental implants placed in Solid-organ transplant (SOT) patients compared to healthy controls. Three databases (PubMed, Web of Sciences and the Cochrane Library) were searched up to June 2020 (PROSPERO CRD42019124896). Case-control and cohort studies reporting data failure rate and marginal bone loss (MBL) of dental implants placed in SOT patients were included. The risk of bias of observational studies was assessed through the Newcastle-Ottawa Scale (NOS). Four case-control studies fulfilled the inclusion criteria, all of low risk of bias. Meta-analyses revealed consistently lower implant failure rate than control populations at patient and implant levels. SOT patients had a significant difference of -18% (p-value &lt;0.001) of MLB towards healthy patients. SOT status poses no serious threat to implant survival. Overall, this group of patients presented lower levels of dental implant failure rate and marginal bone loss compared to otherwise healthy patients. Further intervention trials with wider sample size and longer follow-ups are necessary to confirm these summary results.

scholarly journals Dental Implant Failure Rate and Marginal Bone Loss in Transplanted Patients: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 1 (2) ◽  
pp. 85-96
Author(s):  
Marcela Paraizo ◽  
João Botelho ◽  
Vanessa Machado ◽  
José João Mendes ◽  
Ricardo Alves ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Loss ◽  
Dental Implants ◽  
Dental Implant ◽  
Failure Rate ◽  
Case Control ◽  
Risk Of Bias ◽  
Implant Failure ◽  
Cochrane Library ◽  
Marginal Bone Loss

This systematic review investigates the failure rate and marginal bone loss (MBL) of dental implants placed in patients undergoing solid-organ transplant (SOT) compared to healthy controls. Three databases (PubMed, Web of Sciences, and the Cochrane Library) were searched up to June 2020 (PROSPERO CRD42019124896). Case-control and cohort studies reporting data failure rate and marginal bone loss (MBL) of dental implants placed in SOT patients were included. The risk of bias of observational studies was assessed through the Newcastle-Ottawa Scale (NOS). Four case-control studies fulfilled the inclusion criteria; all had low risk of bias. Meta-analyses revealed consistently lower implant failure rate than control populations at patient and implant levels. SOT patients had a significant difference of −18% (p-value < 0.001) MBL compared to healthy patients. SOT status poses no serious threat to implant survival. Overall, this group of patients presented lower levels of dental implant failure rate and marginal bone loss compared to otherwise healthy patients. Further intervention trials with larger sample size and longer follow-ups are necessary to confirm these summarized results.

scholarly journals Marginal Bone Loss and Aesthetics Around Zirconia and Titanium Dental Implants-A Metanalysis

2020 ◽  
Author(s):  
Pulijala Sathwika ◽  
Rampalli Viswa Chandra
Keyword(s):  
Bone Loss ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Titanium Implants ◽  
Controlled Trials ◽  
Marginal Bone Loss ◽  
Randomized Controlled ◽  
Cie Lab ◽  
Titanium Dental Implants ◽  
Zirconia Implants

AIM: To evaluate and compare the marginal bone loss and aesthetic outcomes of zirconia implants with titanium implants in randomized controlled trials (RCTs). MATERIAL AND METHODS: Electronic [PubMed] and hand searches were performed to identify randomized controlled trials that were published between January 2008 to April 2020 which investigated and compared various outcomes between zirconia and titanium dental implants. Outcomes included assessment of marginal bone loss and aesthetics using spectrophotometric measurements. Meta-analysis was performed to estimate the above parameters among various studies. RESULTS: A total of 58 articles were screened for titles and abstracts. Subsequently 8 articles were selected for data extraction and evaluation. Zirconia implants were investigated and compared to titanium implants for marginal bone loss [MBL]. Customized zirconia and titanium abutments seated over implants were analyzed for aesthetic outcomes using spectrophotometric method using CIE-Lab measurements. Meta-analysis estimated that zirconia implants exhibited marginal bone loss reduction of 0.179mm (95% CI, 0.02 to 0.33) and -0.242mm (95% CI, -4.026 to 3.542) in aesthetic measurements than titanium implants. CONCLUSIONS: No heterogeneity was observed among studies analyzed for marginal bone loss and significant differences were noticed between two groups. Noticeable heterogeneity was observed among studies assessing aesthetics using spectrophotometry and CIE-Lab measurements and results revealed no many significant differences between the two groups.

scholarly journals Eye Acupuncture Treatment for Stroke: A Systematic Review and Meta-Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Zeng-Hua Bai ◽  
Zhi-Xing Zhang ◽  
Chun-Ri Li ◽  
Mei Wang ◽  
Meong-Ju Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Western Medicine ◽  
Current Evidence ◽  
Effect Estimate ◽  
Controlled Trials ◽  
Search Activity ◽  
Randomized Controlled ◽  
Significant Difference ◽  
Eye Acupuncture

There were applications of eye acupuncture for stroke patients. Unfortunately, similar to many other Traditional Chinese Medicine (TCM) treatments, it lacks comprehensive evaluation and system review for its effect and safety.Objective. This study is a systematic review to appraise the safety and effectiveness of eye acupuncture for stroke.Methods. “Eye acupuncture therapy” in eleven databases was searched by randomized controlled trials and quasi-randomized controlled trials. The search activity was ended in April 2014. The data were extracted and assessed by three independent authors. Rev Man 5.0 software was used for data analysis with effect estimate presented as relative risk (RR) and mean difference (MD) with a 95% confidence interval.Results. Sixteen trials (1120 patients) were involved with generally poor methodological quality. The study indicated that when eye acupuncture was combined with western medicine compared to western medicine, there was a significant difference in the areas of mental state, swallow function, and NDS. When eye acupuncture was combined with western medicine and rehabilitation compared to western medicine and rehabilitation, there was significant difference in the changes of SSS, FMA, and constipation symptoms evaluation. No adverse events or side effects have been reported.Conclusions. The current evidence is insufficient and the rigorously designed trials are warranted.

scholarly journals Current Evidence on Traditional Chinese Exercise for Cancers: A Systematic Review of Randomized Controlled Trials

2020 ◽  
Vol 17 (14) ◽  
pp. 5011
Author(s):  
Yang Song ◽  
Dong Sun ◽  
Bíró István ◽  
Anand Thirupathi ◽  
Minjun Liang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Cancer Patients ◽  
Systematic Evaluation ◽  
Current Evidence ◽  
Controlled Trials ◽  
Eligibility Criteria ◽  
Randomized Controlled ◽  
Conventional Medical Treatment ◽  
Larger Sample

Traditional Chinese exercise (TCE) has gradually become one of the widespread complementary therapies for treatment and recovery of cancers. However, evidence based on the systematic evaluation of its efficacy is lacking, and there appears to be no conclusion regarding the setting of TCE interventions. The purpose of this systematic review is to summarize the current randomized controlled trials (RCTs) that outline the effects of TCE on cancer patients. Relevant studies were searched by GOOGLE SCHOLAR, SCIENCEDIRECT, and WEB OF SCIENCE using “traditional Chinese exercise” and “cancer.” Only RCTs published in peer-reviewed English journals were included. A total of 27 studies covering 1616 cancer patients satisfied the eligibility criteria for this review. Despite the methodological limitation and relatively high risk of bias possessed by some included studies, positive evidence was still detected on the effects of TCE on these cancer-related health outcomes in physical, psychological, and physiological parameters. The 60-min or 90-min course of TCE intervention for two to three times per week for 10 to 12 weeks was found to be the most common setting in these studies and has effectively benefited cancer patients. These findings add scientific support to encourage cancer patients to practice TCE during or after conventional medical treatment. Nevertheless, future well-designed RCTs with improved methodology and larger sample size on this field are much warranted for further verification.

scholarly journals Acupuncture Treatment for Chronic Pelvic Pain in Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Soo-Hyun Sung ◽  
Angela-Dong-Min Sung ◽  
Hyun-Kyung Sung ◽  
Tteul-E-Bom An ◽  
Kyeong Han Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Pelvic Pain ◽  
Chronic Pelvic Pain ◽  
Acupuncture Treatment ◽  
Meta Analysis ◽  
Modern Technology ◽  
Current Evidence ◽  
Controlled Trials ◽  
Randomized Controlled

Aim of the Study. This systematic review and meta-analysis aims to evaluate the current evidence from randomized controlled trials (RCTs) related to the effectiveness and safety of acupuncture treatment (AT), including electroacupuncture or thread-embedding therapy in combination with modern technology, for chronic pelvic pain (CPP) in women. Materials and Methods. We searched 12 electronic databases up to December 2017. All randomized controlled trials evaluating the effect of AT for CPP were considered. Results. Four RCTs with 474 participants were included. The methodological quality of included studies was generally low. The results of meta-analysis of two studies showed that AT combined with conventional treatment (CT) was associated with significantly reduced CPP, based on the total effectiveness rate (n=277, mean difference = 1.29, confidence interval = 1.13 to 1.47, P=0.0001, I2 = 0%). Conclusions. This review suggests the potential of AT combined with CT compared to CT alone for treating female CPP. However, there is insufficient evidence to conclude that AT can be recommended as a complementary and alternative (CAM) treatment for women with CPP. To draw a firm conclusion, future studies should require not only lager, more rigorously designed RCTs but also research on different AT types. Protocol Registration Number. This study is registered with PROSPERO 2018 (CRD42018088627).

scholarly journals Short Dental Implants (≤7mm) Versus Longer Implants in Augmented Bone Area: A Meta-Analysis of Randomized Controlled Trials

2018 ◽  
Vol 12 (1) ◽  
pp. 354-365 ◽  
Author(s):  
Priscila N. Uehara ◽  
Victor Haruo Matsubara ◽  
Fernando Igai ◽  
Newton Sesma ◽  
Marcio K. Mukai ◽  
...  
Keyword(s):  
Survival Rate ◽  
Bone Loss ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Statistical Significance ◽  
Controlled Trials ◽  
Bone Area ◽  
Marginal Bone Loss ◽  
Randomized Controlled ◽  
Short Implants

Aim: The aim of this systematic review was to compare the survival rate and the marginal bone loss between short implants (≤7 mm) placed in the atrophic area and longer implants placed in the augmented bone area of posterior regions of maxillaries. Methods: Electronic search using three databases was performed up to May 2017 to identify Randomized Controlled Trials (RCT) assessing short implants survival with a minimal follow-up of 12 months post-loading. For the meta-analysis, a Risk Difference (RD) with the 95% Confidence Interval (CI) was used to pool the results of implant failure rate for each treatment group. For the marginal bone changes, Mean Differences (MD) with 95% CI were calculated. Results: Seven randomized controlled trials met the inclusion criteria, being included in qualitative and quantitative analyses. The RD between the short implant group and the control group was -0.02 (95% CI: -0.04 to 0.00), I2=0 and Chi2=3.14, indicating a favorable survival rate for short implant, but with no statistical significance (p=0.09). Discussion: For marginal bone loss, the mean difference was -0,13 (95%CI: -0.22 to -0.05), favoring the test group with statistical significance (p=0.002). The studies showed more heterogeneity for bone loss compared to survival rate. Short and longer implants showed similar survival rates after one year of loading, however the marginal bone loss around short implants was lower than in longer implants sites. Conclusion: Placement of implants ≤7 mm of length was found to be a predictable alternative for the rehabilitation of atrophic posterior regions, avoiding all the disadvantages intrinsic to bone augmentation procedures.

scholarly journals Chinese Herbal Medicine for Aspirin Resistance: A Systematic Review of Randomized Controlled Trials

2014 ◽  
Vol 2014 ◽  
pp. 1-16
Author(s):  
Ai-ju Liu ◽  
Hui-qin Li ◽  
Ji-huang Li ◽  
Yuan-yuan Wang ◽  
Dong Chen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Herbal Medicine ◽  
Randomized Controlled Trials ◽  
Chinese Herbal Medicine ◽  
Aspirin Resistance ◽  
Current Evidence ◽  
Controlled Trials ◽  
Efficacy And Safety ◽  
Randomized Controlled ◽  
Chinese Herbal

Aspirin resistance (AR) is a prevalent phenomenon and leads to significant clinical consequences, but the current evidence for effective interventional strategy is insufficient. The objective of this systematic review is thus to assess the efficacy and safety of Chinese herbal medicine (CHM) for AR. A systematical literature search was conducted in 6 databases until December 2012 to identify randomized controlled trials (RCTs) of CHM for AR. As a result, sixteen RCTs with a total of 1011 subjects were identified, suggesting that the interests of the medical profession and the public in the use of CHM for AR have grown considerably in the recent years. Tongxinluo capsule and Danshen-based prescriptions were the most frequently used herbal prescriptions, while danshen root, milkvetch root, Leech, and Rosewood were the most frequently used single herbs. Despite the apparent reported positive findings, it is premature to determine the efficacy and safety of CHM for the treatment of AR due to poor methodological quality and insufficient safety data. However, CHMs appeared to be well tolerated in all included studies. Thus, CHM as a promising candidate is worthy of improvement and development for further clinical AR trials. Large sample-size and well-designed rigorous RCTs are needed.

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