scholarly journals Perspective: Inexorable beta cell deterioration via oxidative stress as a secondary complication of Type 2 Diabetes

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
R Paul Robertson
Keyword(s):  
Oxidative Stress ◽  
Type 2 Diabetes ◽  
Beta Cell ◽  
Secondary Complication

Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in Type 2 diabetes

2007 ◽  
Vol 48 (2-3) ◽  
pp. 139-146 ◽  
Author(s):  
R. Paul Robertson ◽  
Huarong Zhou ◽  
Tao Zhang ◽  
Jamie S. Harmon
Keyword(s):  
Oxidative Stress ◽  
Type 2 Diabetes ◽  
Beta Cell ◽  
Glucose Toxicity ◽  
Chronic Oxidative Stress

scholarly journals Oxidative stress in type 2 diabetes mellitus and methods for its correction

2011 ◽  
Vol 57 (6) ◽  
pp. 52-56 ◽  
Author(s):  
A S Ametov ◽  
O L Solov'eva
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Beta Cell ◽  
Vascular Complications ◽  
Low Density Lipoproteins ◽  
Hypoglycemic Agents ◽  
Low Density

Recent publications concerning mechanisms of late vascular complications of type 2 diabetes mellitus lay emphasis on oxidative stress as a major factor contributing to their development. Moreover, oxidative stress induced by hyperglycemia is considered to be the main cause underlying beta-cell lesion that accelerates progression of diabetes. Modern hypoglycemic agents must have additional properties preventing the development of vascular complications. Gliclazide MV is considered to be a medicine displaying anti-atherogenic and anti-oxidative properties that promote the survival of beta-cells exposed to oxidative stress and increase the resistance of low-density lipoproteins to oxidation.

66-OR: Remission of Type 2 Diabetes for Two Years Is Associated with Full Recovery of Beta-Cell Functional Mass in the Diabetes Remission Clinical Trial (DiRECT)

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 66-OR
Author(s):  
SVIATLANA V. ZHYZHNEUSKAYA ◽  
AHMAD AL-MRABEH ◽  
ALISON C. BARNES ◽  
BENJAMIN ARIBISALA ◽  
KIEREN G. HOLLINGSWORTH ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Clinical Trial ◽  
Beta Cell ◽  
Diabetes Remission ◽  
Full Recovery

78-OR: Glycaemia, Beta-Cell Function, and Incretin Hormones Post-OGTT One Year after Gastric Bypass and Sleeve Gastrectomy in Patients with Morbid Obesity and Type 2 Diabetes: An RCT (Oseberg Study)

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 78-OR
Author(s):  
FARHAT FATIMA ◽  
JØRAN HJELMESÆTH ◽  
KARE I. BIRKELAND ◽  
HANNE L. GULSETH ◽  
JENS K. HERTEL ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Morbid Obesity ◽  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Incretin Hormones ◽  
One Year
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