scholarly journals Therapeutic effectiveness of moderate energy restriction in obese Tunisian women

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Bouchoucha Mongia ◽  
Bouchoucha Rim ◽  
Bellali Hédia ◽  
Akrout Mouna ◽  
Kallel Amani ◽  
...  
Keyword(s):  
Energy Restriction ◽  
Therapeutic Effectiveness ◽  
Moderate Energy

scholarly journals Moderate energy restriction-induced weight loss affects circulating IGF levels independent of dietary composition

2010 ◽  
Vol 162 (6) ◽  
pp. 1075-1082 ◽  
Author(s):  
Damien P Belobrajdic ◽  
Jan Frystyk ◽  
Nilani Jeyaratnaganthan ◽  
Ulrick Espelund ◽  
Allan Flyvbjerg ◽  
...  
Keyword(s):  
Weight Loss ◽  
Red Meat ◽  
Energy Restriction ◽  
Model Assessment ◽  
Meat Content ◽  
Igf System ◽  
Igf Binding ◽  
Moderate Energy ◽  
Isocaloric Diets ◽  
Igfbp 3

BackgroundObesity is associated with major changes in the circulating IGF system. However, it is not clear to what extent the IGF system is normalized following diet, and the possible role of different types of diet is also unknown.ObjectiveTo compare changes in the circulating IGF system following 12 weeks of moderate energy restriction (7000 kJ/day) in overweight or obese males on a high protein high red meat diet (HP) or a high carbohydrate diet (HC).DesignSeventy-six men (mean age, 51±1.0 years; body mass index, 32.8±0.5 kg/m2) were allocated to matched groups treated with isocaloric diets of HP (n=34) or HC (n=42). Outcome measures were weight, body composition, IGF-related peptides, homoeostasis model assessment of insulin resistance (HOMA1-IR) and adipokines.ResultsWeight loss did not differ between diets (HP 8.5±0.6 kg; HC 8.2±0.6 kg,P>0.05). IGF-related peptides increased total IGF1 (HP 23%; HC 18%,P<0.0001), bioactive IGF1 (HP 18%; HC 15%,P<0.002), IGF1:IGF-binding protein-3 (IGFBP-3; HP 29%; HC 22%,P<0.0001) and IGFBP-1 (HP 24%; HC 25%,P<0.01). By contrast, decreases were observed in IGFBP-3 (HP −4%; HC −3%,P<0.01), pro-IGF2 (HP −3%; HC −6%,P=0.001), total IGF2 (HP −7%; HC −3%,P=0.001) and sIGF2R (HP −10%; HC −6%,P<0.005). Only IGFBP-2 increased differentially by diet (HP 34%; HC 50%,P<0.0001, dietP<0.05). Adiponectin increased in both diets, but leptin and HOMA-IR decreased (P<0.001).ConclusionsWeight loss induced by moderate energy restriction modulated the IGF system independent of dietary protein or red meat content. The effect of diet on IGFBP-2 appeared to have limited biological effect as total IGF2 and pro-IGF2 did not change.

scholarly journals Metabolic and Body Composition Responses to a Moderate Energy Restriction, Abundant Protein Diet in Type 2 Diabetic Adults

2013 ◽  
Vol 37 ◽  
pp. S66
Author(s):  
Ayla Coussa ◽  
Errol B. Marliss ◽  
Stephanie Chevalier ◽  
Jose A. Morais ◽  
Marie Lamarche ◽  
...  
Keyword(s):  
Body Composition ◽  
Energy Restriction ◽  
Protein Diet ◽  
Abundant Protein ◽  
Moderate Energy ◽  
Type 2 Diabetic

scholarly journals Energy cost of walking and body composition changes during a 9-month multidisciplinary weight reduction program and 4-month follow-up in adolescents with obesity

2021 ◽  
Author(s):  
Mattia D'Alleva ◽  
Federica Gonnelli ◽  
Filippo Vaccari ◽  
Yves Boirie ◽  
Christophe Montaurier ◽  
...  
Keyword(s):  
Body Composition ◽  
Weight Reduction ◽  
Energy Cost ◽  
Exercise Tolerance ◽  
Energy Restriction ◽  
Obese Adolescents ◽  
Weight Reduction Program ◽  
Reduction Program ◽  
Moderate Energy

The purpose of the present study was to investigate changes in the energy cost of locomotion during walking (Cw) related to the changes in body mass (BM, kg) and body composition in adolescents with obesity. Twenty-six (12 boys and 14 girls) obese adolescents (mean: BMI, 33.6±3.7 kg/m2; 42.7±4.5 % fat mass) followed a 9-month multidisciplinary inpatient weight-reduction program consisting of lifestyle education, moderate energy restriction, and regular physical activity in a specialized institution. At baseline (M0), by the end of the 9-month program (M9) and after 4-months follow-up (M13), V’O2 and V’CO2 of standardized activity program were assessed by whole-body indirect calorimetry over 24 hours, and body composition was assessed by DXA. At M9, adolescents showed a 18% reduction in BM (p<0.001), 40% in total FM; while FFM (kg) remained stable in boys but decreased by ~6% in girls (p=0.001). Similarly, the mean Cw decreased by 20% (p<0.001). At M13, BM, FM and Cw were slightly higher compared than at M9. In conclusion, moderate energy restriction and regular moderate physical activities improved walking economy, improved exercise tolerance and induced beneficial changes in body composition of adolescents with obesity. Novelty bullets • Reduction of FM in the trunk region, and consequently reducing the work carried out by respiratory muscles, contribute to reduce Cw in adolescents with obesity. • A lower cost of walking can be effective in improving exercise tolerance and quality of life in obese adolescents.

Exercise enhances dietary compliance during moderate energy restriction in obese women

1995 ◽  
Vol 62 (2) ◽  
pp. 345-349 ◽  
Author(s):  
S B Racette ◽  
D A Schoeller ◽  
R F Kushner ◽  
K M Neil
Keyword(s):  
Energy Restriction ◽  
Obese Women ◽  
Dietary Compliance ◽  
Moderate Energy

Metabolic programming of sirtuin 1 (SIRT1) expression by moderate energy restriction during gestation in rats may be related to obesity susceptibility in later life

2012 ◽  
Vol 109 (4) ◽  
pp. 757-764 ◽  
Author(s):  
Mariona Palou ◽  
Teresa Priego ◽  
Juana Sánchez ◽  
Andreu Palou ◽  
Catalina Picó
Keyword(s):  
Body Weight ◽  
Mrna Expression ◽  
Energy Restriction ◽  
Metabolic Programming ◽  
Sirtuin 1 ◽  
Mrna Levels ◽  
Dependent Manner ◽  
Peripheral Tissues ◽  
Moderate Energy ◽  
Obesity Susceptibility

In rats, 20 % gestational energy restriction programmes offspring for higher food intake, which in adulthood results in higher body weight in males but not in females. Here, we aimed to assess whether the effects of moderate energy restriction during gestation and the sex-related outcomes on adult body weight may be related to the metabolic programming of sirtuin expression in different tissues. For this purpose, 25-d-old offspring of control and 20 % energy-restricted (ER) rats (from days 1–12 of pregnancy) were studied. Body weight and the weight of white adipose tissue (WAT) depots and liver were recorded and mRNA expression of sirtuin 1 (SIRT1) and selected genes in the WAT, liver, muscle and hypothalamus were analysed. No differences were found in body weight or the weight of WAT and liver between the control and ER animals. A similar pattern of SIRT1 mRNA expression was found in the WAT, liver and skeletal muscle of ER animals, but in a sex-dependent manner: ER males showed lower SIRT1 mRNA levels than the controls, while no differences were found in females. A sex-different pattern was also observed in the hypothalamus. ER males, but not females, also showed lower mRNA levels of adipose TAG lipase (ATGL) and uncoupling protein 2 in WAT and of sterol response element binding protein 1c and stearoyl-CoA desaturase-1 in the liver. Both sexes of ER animals showed lower mRNA levels of 5′ adenosine monophosphate-activated protein kinase and ATGL in the liver. In conclusion, moderate maternal energy restriction during gestation programmes a particular, sex-dependent gene expression profile of SIRT1 in different peripheral tissues, which may be related to obesity predisposition in adulthood; therefore SIRT1 expression emerges as a potential early biomarker of obesity susceptibility.

scholarly journals Moderate energy restriction with high protein diet results in healthier outcome in women

2010 ◽  
Vol 7 (1) ◽  
Author(s):  
Antti A Mero ◽  
Heikki Huovinen ◽  
Olle Matintupa ◽  
Juha J Hulmi ◽  
Risto Puurtinen ◽  
...  
Keyword(s):  
High Protein Diet ◽  
Energy Restriction ◽  
High Protein ◽  
Protein Diet ◽  
Moderate Energy

scholarly journals The effects of moderate energy restriction on apnoea severity and CVD risk factors in obese patients with obstructive sleep apnoea

2015 ◽  
Vol 114 (12) ◽  
pp. 2022-2031 ◽  
Author(s):  
Julia Freitas Rodrigues Fernandes ◽  
Luciene da Silva Araújo ◽  
Sergio Emanuel Kaiser ◽  
Antonio Felipe Sanjuliani ◽  
Márcia Regina Simas Torres Klein
Keyword(s):  
Risk Factors ◽  
Obstructive Sleep Apnoea ◽  
Sympathetic Activity ◽  
Sleep Apnoea ◽  
Energy Restriction ◽  
Obese Patients ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Obstructive Sleep ◽  
Moderate Energy

AbstractNutritional intervention for weight loss is one of the treatment options for obstructive sleep apnoea (OSA) in patients with overweight or obesity. However, the effects of moderate energy restriction on OSA severity are not yet known. The present study aimed to evaluate the effects of moderate energy restriction on OSA severity and CVD risk factors in obese patients with OSA. In this 16-week randomised clinical trial, twenty-one obese subjects aged 20–55 years and presenting an apnoea/hypopnoea index (AHI)≥5 events/h were randomised into two groups: the energy restriction group (ERG) and the control group (CG). The ERG was instructed to follow an energy-restricted diet −3347·2 kJ/d (−800 kcal/d) and the CG was advised not to change their food intake. At the beginning and at the end of the study, participants underwent evaluation of the following: OSA (Watch-PAT200®), nutritional parameters, blood pressure, sympathetic activity, inflammatory biomarkers, metabolic profile and endothelial function. The ERG (n11), compared with the CG (n10), had a significantly greater reduction in body weight (Cohen’sd=−1·19;P<0·001), in AHI (Cohen’sd=−0·95;P=0·04) and in plasma concentrations of adrenaline (Cohen’sd=−1·02;P=0·04) as well as a significantly greater increase in minimum O2saturation (Cohen’sd=1·08;P=0·03). Although energy restriction was not associated with significant improvements in CVD risk factors, medium-to-large effect sizes were observed, suggesting that the statistically non-significant difference between groups may be due to the small sample size. This study suggests that in obese patients with OSA, moderate energy restriction is able to reduce the parameters of OSA severity and sympathetic activity.

Abstract 461: Effects Of Energy Restriction On Sleep Apnea, Blood Pressure, Sympathetic Activity, Oxidative Stress, Inflammatory Biomarkers, Endothelial Function And Metabolic Profile In Obese Patients With Obstructive Sleep Apnea

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Julia F Fernandes ◽  
Luciene S Araújo ◽  
Maria de Lourdes G Rodrigues ◽  
Debora C Valença ◽  
José Firmino N Neto ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Sleep Apnea ◽  
Endothelial Function ◽  
Sympathetic Activity ◽  
Metabolic Profile ◽  
Energy Restriction ◽  
Obese Patients ◽  
Body Adiposity ◽  
Obstructive Sleep ◽  
Moderate Energy

Introduction: Weight loss is one of the treatment options for obstructive sleep apnea (OSA) in patients with excess body adiposity. However, the effects of moderate energy restriction on OSA are not known. Objective: To evaluate the effects of moderate energy restriction on severity of OSA, blood pressure (BP), sympathetic activity, oxidative stress, inflammation, body adiposity, metabolic profile and endothelial function in obese patients with OSA. Methods: A 16-week randomized clinical trial, involving 21 obese subjects aged 20-55y with apnea/hipopnea index (AHI) ≥ 5 events/h. Subjects were randomized in 2 groups: 11 in energy restriction group (ERG) and 10 in control group (CG). ERG was instructed to follow an energy-restricted diet (-800 kcal/day) and CG was advised not to change food intake. At the beginning and at the end of the study, participants underwent evaluation of: OSA with Watch- PAT200® including the determination of OSA severity parameters, body adiposity, BP, plasma catecholamines, c-reactive protein (CRP), adiponectin, malondialdehyde, metabolism of glucose, lipid profile and endothelial function (Endo PAT 2000®). Results: ERG, compared to CG, presented significantly greater reduction in body weight (-5.6±1.8 vs. 0.4±1.2kg, p<0.001) and in all parameters of body adiposity; AHI (-7.2±2.8 vs. 0.1±1.9 events/h, p=0.04); number of O2 desaturation >4% (-33.7±15.6 vs. 1.8±7.9, p=0.04); plasma adrenaline (-12.7±3.0 vs. -1.3±3.9pg/mL, p=0.04); and significantly greater increase in minimum O2 saturation (4.6±1.6 vs. -0.6±1.4%, p=0.03). ERG showed greater decrease, however without statistical significance, in systolic BP (-4.2±1.9 vs. 2.3±1.4mmHg, p=0.05), insulin (-5.1±1.9 vs. -0.7±1.3μU/mL, p=0.07) and HOMA-IR (-1.2±0.5 vs. -0.08±0.3, p=0.09). During the study period, changes in body adiposity presented significant correlation with changes in parameters of OSA severity, BP, insulin, HOMA-IR, norepinephrine and adiponectin. Changes in parameters of OSA severity presented significant association with changes in CRP. Conclusions: This study suggests that in obese patients with OSA moderate energy restriction is able to reduce body adiposity, parameters of OSA severity and sympathetic nervous system activity.

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