ApoE4 genotype and cognitive performance in Korean health examinees with subjective memory complaints: A retrospective cross-sectional study

ABSTRACTBackground:Low- and middle-income countries such as Vietnam are home to a majority of the world's population with dementia, yet little is known regarding how individuals in these countries perceive memory problems that might be indicative of cognitive impairment. This study examined the prevalence and correlates of subjective memory complaints (SMCs) in Vietnamese adults in Da Nang, Vietnam.Methods:A stratified sample of 600 adults (aged ≥ 55 years) living in Da Nang, Vietnam, and surrounding areas were recruited to participate in a cross-sectional study. Students and faculty from the National Technical Medical College Number 2 administered questionnaires in participants’ homes regarding socio-demographic characteristics, functional health, social support, cognitive and mental health, and SMCs. Descriptive and stepwise regression analyses examined the prevalence and correlates of SMCs.Results:Approximately 64% of the sample reported at least poor memory and 39% said that memory interfered with their daily life at least somewhat. Multivariate regression analyses (adjusted for all covariates) showed that depressive symptoms, cognitive impairment, self-rated health and pain, and material hardship were associated with SMCs.Conclusions:Prevalence of SMCs as well as depressive symptoms was high in this Vietnamese population. Although future research using more detailed measures of subjective memory and which include longitudinal data are required, the need for physicians to routinely assess Vietnamese patients for depression, SMCs, and cognitive impairment may be warranted.

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Multimorbidity and its relation to subjective memory complaints in a large general population of older adults

International Psychogeriatrics ◽

10.1017/s1041610210002024 ◽

2010 ◽

Vol 23 (4) ◽

pp. 616-624 ◽

Cited By ~ 24

Author(s):

S. Aarts ◽

M. van den Akker ◽

K. J. Hajema ◽

A. M. van Ingen ◽

J. F. M. Metsemakers ◽

...

Keyword(s):

Age Groups ◽

Cross Sectional Study ◽

Postal Survey ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Cross Sectional ◽

The Public ◽

Memory Complaints ◽

Health Related ◽

The Relationship

ABSTRACTBackground: Multimorbidity has been suggested to be associated with a variety of negative health-related outcomes. The present study was designed to evaluate the association between multimorbidity and subjective memory complaints.Methods: This cross-sectional study was based on data obtained from a postal survey designed by the Public Health Service (Gemeentelijke Gezondheids Dienst, GGD) involving 15,188 persons aged 55 years and over living independently in Limburg, the Netherlands. Multivariate logistic regression analyses, adjusted for potentially important covariates, were performed to evaluate the association between self-reported multimorbidity and three outcomes related to subjective memory complaints.Results: Multimorbidity was indeed related to subjective memory complaints. The association between multimorbidity and subjective memory complaints was positively influenced by age. Moreover, multimorbidity was related to the degree of worrying about memory complaints in people who perceived themselves as forgetful. Multimorbidity was also associated with reporting a larger increase in these subjective memory complaints during the past year. In this latter case, multimorbidity had more prognostic capability in men than in women. Psychological distress was related to all three subjective memory-related outcome measures.Conclusions: In our sample, which was representative of the Dutch population, multimorbidity was associated with subjective memory complaints. The relationship between multimorbidity and subjective memory complaints differed between men and women and between age groups.

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Supplemental Material for Environment and Cognitive Aging: A Cross-Sectional Study of Place of Residence and Cognitive Performance in the Irish Longitudinal Study on Aging

Neuropsychology ◽

10.1037/neu0000253.supp ◽

2015 ◽

Keyword(s):

Longitudinal Study ◽

Cognitive Performance ◽

Cognitive Aging ◽

Cross Sectional Study ◽

Sectional Study ◽

Place Of Residence ◽

Cross Sectional

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Subjective Memory Complaints and Mild Cognitive Impairment

European Psychiatry ◽

10.1016/s0924-9338(09)71326-4 ◽

2009 ◽

Vol 24 (S1) ◽

pp. 1-1 ◽

Cited By ~ 2

Author(s):

M. Simoes ◽

L.C. Castro ◽

O. Ribeiro ◽

T. Salgado ◽

C. Paz

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

The Elderly ◽

Future Research ◽

Older Individuals ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Cross Sectional ◽

Memory Complaints ◽

Increased Risk

Background:Subjective Memory Complaints (SMC) are common in clinical practice. the clinical significance of these subjective complaints among older individuals is not well understood.Aim:To study and discuss the association between SMC and MCI, underlining the importance of an adequate clinical assessment of SMC in the elderly.Methods:Review of the literature.Results:There is no consistent definition of SMC in the literature. Some prospective studies showed an association with objective memory impairments, conceptualizing SMC as a Pre-Mild Cognitive Impairment. SMC are also currently considered to be a core feature of Mild Cognitive Impairment (MCI). Cross-sectional studies and longitudinal studies showed conflicting results concerning the association between SMC and MCI.Discussion:The understanding of the predictive value of SMC in cognitive decline is still poorly understood. It is important to define criteria aimed to increase specificity of memory complaints, allowing an earlier identification of populations with higher risk of MCI. Future research on this complex association is important to identify SMC individuals at increased risk of conversion to MCI and dementia.

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