Clinical utility of calprotectin and lactoferrin as markers of inflammation in patients with inflammatory bowel disease

2010 ◽  
Vol 6 (4) ◽  
pp. 551-558 ◽  
Author(s):  
Roberta Caccaro ◽  
Renata D’Incá ◽  
Giacomo Carlo Sturniolo
2021 ◽  
Vol 27 (Supplement_1) ◽  
pp. S53-S53
Author(s):  
Joshua Paulton ◽  
Amanjot Gill ◽  
Joelle Prevost

Abstract Background Gut-directed hypnosis (GDH) is a complimentary therapy for Inflammatory Bowel Disease (IBD), that can be learnt by patients to practice self-hypnosis. GDH in IBD has augmented remission and improved inflammation. GDH has a history of successful use for Irritable Bowel Syndrome (IBS). In IBD it may also improve IBS-like symptoms in remission and recovery from surgery. GDH is suitable for youth and adult IBD patients. In hypnosis, a relaxed state is inducted then suggestions to subconscious mind processes are made. In IBD, the mechanism of action of GDH is unknown but may influence the disease stress response. Aims Aims are the development of a GDH self-hypnosis protocol for IBD, with appropriate target symptoms. Patients first learn to practice with a clinician, then as complimentary psychotherapy for remission augmentation, IBS-like symptoms, and surgery recovery. Methods GDH is practiced first with a clinician, and then by patients as self-hypnosis (table 1). Patients receive psycho-education on GDH for IBD. Next, appropriate treatment goals are made, based on target symptoms. Relaxation techniques induce patient to a deeply relaxed state. Therapeutic suggestions specific to patient goals are given: verbal suggestions, visualizations, and post-hypnotic suggestions. Suggestions can focus on having a healthy digestive system, inflammation and symptoms reduction, and achievement and sustainment of remission. Patients emerge from hypnosis, are debriefed, and encouraged to practice ongoing self-hypnosis. Results In IBD, GDH self-hypnosis can be learnt from clinicians and practiced by patients as a complimentary therapy. Patients’ achievement and sustainment of remission, with clinical markers of inflammation can be monitored. Patients can monitor subjective improvement of IBS-like symptoms and post surgery, recovery progress can be monitored. Conclusions GDH has a history of use for IBS. In IBD, it has been shown to modulate remission, and may improve IBS-like symptoms, and in surgery recovery. The mechanism of action of GDH in IBD may influence the disease stress response. Clinicians trained in GDH are limited currently. Patients may learn GDH self- hypnosis to as a complimentary psychotherapy.


Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1843
Author(s):  
Marilyn Hagan ◽  
Bu' Hussain Hayee ◽  
Ana Rodriguez-Mateos

(Poly)phenols (PPs) may have a therapeutic benefit in gastrointestinal (GI) disorders, such as irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD). The aim of this review is to summarise the evidence-base in this regard. Observational evidence does not give a clear indication that PP intake has a preventative role for IBD or IBS, while interventional studies suggest these compounds may confer symptomatic and health-related quality of life improvements in known patients. There are inconsistent results for effects on markers of inflammation, but there are promising reports of endoscopic improvement. Work on the effects of PPs on intestinal permeability and oxidative stress is limited and therefore conclusions cannot be formed. Future work on the use of PPs in IBD and IBS will strengthen the understanding of clinical and mechanistic effects.


2009 ◽  
Vol 136 (5) ◽  
pp. A-147 ◽  
Author(s):  
Waqqas Afif ◽  
Edward V. Loftus ◽  
William A. Faubion ◽  
Karen A. Hanson ◽  
William J. Sandborn

2010 ◽  
Vol 105 (5) ◽  
pp. 1133-1139 ◽  
Author(s):  
Waqqas Afif ◽  
Edward V Loftus ◽  
William A Faubion ◽  
Sunanda V Kane ◽  
David H Bruining ◽  
...  

2013 ◽  
Vol 144 (5) ◽  
pp. S-417
Author(s):  
Darren Spearman ◽  
Steven Armbruster ◽  
Corinne L. Maydonovitch ◽  
Ganesh R. Veerappan

Immunology ◽  
2013 ◽  
Vol 140 (1) ◽  
pp. 87-97 ◽  
Author(s):  
Nicholas T. Funderburg ◽  
Samantha R. Stubblefield Park ◽  
Hannah C. Sung ◽  
Gareth Hardy ◽  
Brian Clagett ◽  
...  

2004 ◽  
Vol 39 (Supplement 1) ◽  
pp. S324 ◽  
Author(s):  
R. Berni Canani ◽  
L. Tanturri de Horatio ◽  
M. T. Romano ◽  
F. Manguso ◽  
L. Rapacciuolo ◽  
...  

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