Economic evaluations of point of care testing strategies for active tuberculosis

2013 ◽  
Vol 13 (3) ◽  
pp. 313-325 ◽  
Author(s):  
Alice Zwerling ◽  
David Dowdy
Keyword(s):  
Point Of Care ◽  
Active Tuberculosis ◽  
Economic Evaluations ◽  
Point Of Care Testing ◽  
Testing Strategies

scholarly journals Respiratory tract infections (RTIs) in primary care: narrative review of C reactive protein (CRP) point-of-care testing (POCT) and antibacterial use in patients who present with symptoms of RTI

2020 ◽  
Vol 7 (1) ◽  
pp. e000624
Author(s):  
Jonathan Cooke ◽  
Carl Llor ◽  
Rogier Hopstaken ◽  
Matthew Dryden ◽  
Christopher Butler
Keyword(s):  
Primary Care ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Point Of Care ◽  
Narrative Review ◽  
Economic Evaluations ◽  
Point Of Care Testing ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Tract Infections

Antimicrobial resistance (AMR) continues to be a global problem and continues to be addressed through national strategies to improve diagnostics, develop new antimicrobials and promote antimicrobial stewardship. Patients who attend general (ambulatory) practice with symptoms of respiratory tract infections (RTIs) are invariably assessed by some sort of clinical decision rule (CDR). However, CDRs rely on a cluster of non-specific clinical observations. A narrative review of the literature was undertaken to ascertain the value of C reactive protein (CRP) point-of-care testing (POCT) to guide antibacterial prescribing in adult patients presenting to general practitioner (GP) practices with symptoms of RTI. Studies that were included were Cochrane reviews, systematic reviews, randomised controlled trials, cluster randomised trials, controlled before and after studies, cohort studies and economic evaluations. An overwhelming number of studies demonstrated that the use of CRP tests in patients presenting with RTI symptoms reduces index antibacterial prescribing. GPs and patients report a good acceptability for a CRP POCT and economic evaluations show cost-effectiveness of CRP POCT over existing RTI management in primary care. POCTs increase diagnostic precision for GPs in the better management of patients with RTI. With the rapid development of artificial intelligence, patients will expect greater precision in diagnosing and managing their illnesses. Adopting systems that markedly reduce antibiotic consumption is a no-brainer for governments that are struggling to address the rise in AMR.

Breaking the time and space limitation of point-of-care testing strategies: Photothermometric sensors based on different photothermal agents and materials

2021 ◽  
Vol 447 ◽  
pp. 214149
Author(s):  
Mingming Wei ◽  
Honghong Rao ◽  
Zhengrong Niu ◽  
Xin Xue ◽  
Mingyue Luo ◽  
...  
Keyword(s):  
Point Of Care ◽  
Point Of Care Testing ◽  
Time And Space ◽  
Testing Strategies ◽  
Space Limitation

scholarly journals PMD10 INSIGHTS INTO THE IMPACT OF POINT-OF-CARE TESTING: A SYSTEMATIC REVIEW OF HEALTH-ECONOMIC EVALUATIONS

2019 ◽  
Vol 22 ◽  
pp. S670-S671
Author(s):  
D. Lingervelder ◽  
E. Koffijberg ◽  
G.C.M. Kusters ◽  
M. IJzerman
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Point Of Care ◽  
Economic Evaluations ◽  
Point Of Care Testing ◽  
The Impact

scholarly journals Economic evaluation of point-of-care testing and treatment for sexually transmitted and genital infections in pregnancy in low- and middle-income countries: A systematic review

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0253135
Author(s):  
Olga P. M. Saweri ◽  
Neha Batura ◽  
Rabiah Al Adawiyah ◽  
Louise M. Causer ◽  
William S. Pomat ◽  
...  
Keyword(s):  
Point Of Care ◽  
Economic Evaluations ◽  
Reporting Standards ◽  
Point Of Care Testing ◽  
Genital Infections ◽  
Middle Income ◽  
Sexually Transmitted ◽  
Middle Income Countries ◽  
In Pregnancy ◽  
Low And Middle Income

Background Sexually transmitted and genital infections in pregnancy are associated with adverse pregnancy and birth outcomes. Point-of-care tests for these infections facilitate testing and treatment in a single antenatal clinic visit and may reduce the risk of adverse outcomes. Successful implementation and scale-up depends on understanding comparative effectiveness of such programmes and their comparative costs and cost effectiveness. This systematic review synthesises and appraises evidence from economic evaluations of point-of-care testing and treatment for sexually transmitted and genital infections among pregnant women in low- and middle-income countries. Methods Medline, Embase and Web of Science databases were comprehensively searched using pre-determined criteria. Additional literature was identified by searching Google Scholar and the bibliographies of all included studies. Economic evaluations were eligible if they were set in low- and middle-income countries and assessed antenatal point-of-care testing and treatment for syphilis, chlamydia, gonorrhoea, trichomoniasis, and/or bacterial vaginosis. Studies were analysed using narrative synthesis. Methodological and reporting standards were assessed using two published checklists. Results Sixteen economic evaluations were included in this review; ten based in Africa, three in Latin and South America and three were cross-continent comparisons. Fifteen studies assessed point-of-care testing and treatment for syphilis, while one evaluated chlamydia. Key drivers of cost and cost-effectiveness included disease prevalence; test, treatment, and staff costs; test sensitivity and specificity; and screening and treatment coverage. All studies met 75% or more of the criteria of the Drummond Checklist and 60% of the Consolidated Health Economics Evaluation Reporting Standards. Conclusions Generally, point-of-care testing and treatment was cost-effective compared to no screening, syndromic management, and laboratory-based testing. Future economic evaluations should consider other common infections, and their lifetime impact on mothers and babies. Complementary affordability and equity analyses would strengthen the case for greater investment in antenatal point-of-care testing and treatment for sexually transmitted and genital infections.

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