Correlation between skeletal muscle mass index and parameters of respiratory function and muscle strength in young healthy adults according to gender

Background: Sarcopenia is a muscle disease in loss of muscle strength, mass, and function associated with aging. Although protective effects of exercise on muscle mass and function are generally recognized, research findings in sarcopenic adults are inconsistent. It is necessary to conduct a systematic review to determine the effects of exercise on muscle strength, body composition, and physical performance in older adults with sarcopenia, and to examine the potential moderators including sociodemographic characteristics and exercise-related factors.Methods: Six electronical academic databases (Medline, Embase, CINAHL, Scopus, Cochrane Library, and SPORTDiscus) were used to retrieve the eligible studies from inception to May 2020. Two reviewers independently selected and extracted the data from each included study, and effect sizes were calculated by employing random-effect models with 95% confidential interval (CI). The Physiotherapy Evidence Database (PEDro) scale was used to assess study quality.Results: Seventeen studies (985 participants with sarcopenia, aged 67.6–86 years) were included in this review study. The meta-analytic results showed significant improvements in muscle strength [grip strength, SMD = 0.30, 95% CI (0.15, 0.45), I2 = 6%, p < 0.01; knee extension, SMD = 0.32, 95% CI (0.15, 0.50), I2 = 0%, p < 0.01; and chair and stand, SMD = 0.56, 95% CI (0.30, 0.81), I2 = 36%, p < 0.01], in physical performance [timed up and go, SMD = 0.74, 95% CI (0.48, 1.00), I2 = 0%, p < 0.01; and gait speed, SMD = 0.59, 95% CI (0.35, 0.82), I2 = 62%, p < 0.01], and in body composition [skeletal muscle mass index, SMD = 0.37, 95% CI (0.15, 0.58), I2 = 16%, p < 0.01; and appendicular skeletal muscle, SMD = 0.31, 95% CI (0.13, 0.49), I2 = 20%, p < 0.01]. However, there were no significant differences in other body composition (SMD = 0.20–0.36). Additionally, meta-regression revealed that the higher percent of female participants was significantly associated with improved gait speed (β = 0.0096, p = 0.03) and decreased skeletal muscle mass index (β = −0.0092, p = 0.01).Conclusions: The current meta-analysis suggests that exercise is a beneficial therapy, which has protective effects for older adults with sarcopenia. Some beneficial effects may be moderated by gender and exercise intensity.

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Association between hand muscle thickness and whole-body skeletal muscle mass in healthy adults: a pilot study

Journal of Physical Therapy Science ◽

10.1589/jpts.29.1644 ◽

2017 ◽

Vol 29 (9) ◽

pp. 1644-1648 ◽

Cited By ~ 6

Author(s):

Akio Morimoto ◽

Tadashi Suga ◽

Nobuaki Tottori ◽

Michio Wachi ◽

Jun Misaki ◽

...

Keyword(s):

Skeletal Muscle ◽

Pilot Study ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Muscle Thickness ◽

Healthy Adults ◽

Whole Body ◽

Hand Muscle

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Augmentation Index Is Inversely Associated with Skeletal Muscle Mass, Muscle Strength, and Anaerobic Power in Young Male Adults: A Preliminary Study

Applied Sciences ◽

10.3390/app11073146 ◽

2021 ◽

Vol 11 (7) ◽

pp. 3146

Author(s):

Dongmin Lee ◽

Kyengho Byun ◽

Moon-Hyon Hwang ◽

Sewon Lee

Keyword(s):

Skeletal Muscle ◽

Muscle Strength ◽

Arterial Stiffness ◽

Muscle Mass ◽

Muscular Strength ◽

Skeletal Muscle Mass ◽

Augmentation Index ◽

Anaerobic Power ◽

Negatively Associated ◽

Increased Risk

Arterial stiffness is associated with an increased risk of cardiovascular disease. Previous studies have shown that there is a negative correlation between arterial stiffness and variables such as skeletal muscle mass, muscular strength, and anaerobic power in older individuals. However, little research has been undertaken on relationships in healthy young adults. This study presents a preliminary research that investigates the association between arterial stiffness and muscular factors in healthy male college students. Twenty-three healthy young males (23.9 ± 0.5 years) participated in the study. The participants visited the laboratory, and variables including body composition, blood pressure, arterial stiffness, blood parameters, grip strength, and anaerobic power were measured. Measurements of augmentation index (AIx) and brachial-ankle pulse wave velocity (baPWV) were performed to determine arterial stiffness. There were significant positive correlations among skeletal muscle mass, muscle strength, and anaerobic power in healthy young adult males. AIx was negatively associated with a skeletal muscle mass (r = −0.785, p < 0.01), muscular strength (r = −0.500, p < 0.05), and anaerobic power (r = −0.469, p < 0.05), respectively. Likewise, AIx@75 corrected with a heart rate of 75 was negatively associated with skeletal muscle mass (r = −0.738, p < 0.01), muscular strength (r = −0.461, p < 0.05), and anaerobic power (r = −0.420, p < 0.05) respectively. However, the baPWV showed no correlation with all muscular factors. Our findings suggest that maintaining high levels of skeletal muscle mass, muscular strength, and anaerobic power from relatively young age may lower AIx.

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Relationships between changes in the skeletal muscle mass index and number of days needed for independent gait after cardiac surgery

Physiotherapy ◽

10.1016/j.physio.2015.03.1954 ◽

2015 ◽

Vol 101 ◽

pp. e1069 ◽

Cited By ~ 1

Author(s):

M. Nakajima ◽

M. Morishita ◽

S. Yuguchi ◽

K. Saito ◽

T. Matsuo ◽

...

Keyword(s):

Skeletal Muscle ◽

Cardiac Surgery ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Skeletal Muscle Mass Index

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Validation of cutoffs for skeletal muscle mass index based on computed tomography analysis against dual energy X-ray absorptiometry in patients with cirrhosis: the KIRRHOS study

Annals of Gastroenterology ◽

10.20524/aog.2019.0432 ◽

2019 ◽

Author(s):

Alexandra Georgiou

Keyword(s):

Computed Tomography ◽

Skeletal Muscle ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Dual Energy ◽

X Ray ◽

Skeletal Muscle Mass Index ◽

Tomography Analysis

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Skeletal muscle mass at C3 may not be a strong predictor for skeletal muscle mass at L3 in sarcopenic patients with head and neck cancer

PLoS ONE ◽

10.1371/journal.pone.0254844 ◽

2021 ◽

Vol 16 (7) ◽

pp. e0254844

Author(s):

Joon-Kee Yoon ◽

Jeon Yeob Jang ◽

Young-Sil An ◽

Su Jin Lee

Keyword(s):

Skeletal Muscle ◽

Head And Neck Cancer ◽

Diagnostic Accuracy ◽

Prediction Model ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Strong Predictor ◽

Healthy Adults ◽

Muscle Area ◽

The Relationship

Purpose To evaluate the feasibility of using skeletal muscle mass (SMM) at C3 (C3 SMM) as a diagnostic marker for sarcopenia in head and neck cancer (HNC) patients. Methods We evaluated 165 HNC patients and 42 healthy adults who underwent 18F-fluorodeoxyglucose positron emission tomography/computed tomography scans. The paravertebral muscle area at C3 and skeletal muscle area at L3 were measured by CT. Pearson’s correlation was used to assess the relationship between L3 and C3 SMMs. The prediction model for L3 SMM was developed by multiple linear regression. Then the correlation and the agreement between actual and predicted L3 SMMs were assessed. To evaluate the diagnostic value of C3 SMM for sarcopenia, the receiver operating characteristics (ROC) curves were analyzed. Results Of the 165 HNC patients, 61 (37.0%) were sarcopenic and 104 (63.0%) were non-sarcopenic. A very strong correlation was found between L3 SMM and C3 SMM in both healthy adults (r = 0.864) and non-sarcopenic patients (r = 0.876), while a fair association was found in sarcopenic patients (r = 0.381). Prediction model showed a very strong correlation between actual SMM and predicted L3 SMM in both non-sarcopenic patients and healthy adults (r > 0.9), whereas the relationship was moderate in sarcopenic patients (r = 0.7633). The agreement between two measurements was good for healthy subjects and non-sarcopenic patients, while it was poor for sarcopenic patients. On ROC analysis, predicted L3 SMM showed poor diagnostic accuracy for sarcopenia. Conclusions A correlation between L3 and C3 SMMs was weak in sarcopenic patients. A prediction model also showed a poor diagnostic accuracy. Therefore, C3 SMM may not be a strong predictor for L3 SMM in sarcopenic patients with HNC.

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Comparison of the prevalence of sarcopenia using skeletal muscle mass index and calf circumference applying the European consensus definition in elderly Mexican women

Geriatrics and Gerontology International ◽

10.1111/ggi.12652 ◽

2015 ◽

Vol 17 (1) ◽

pp. 161-170 ◽

Cited By ~ 13

Author(s):

Maria Consuelo Velazquez-Alva ◽

Maria Esther Irigoyen Camacho ◽

Irina Lazarevich ◽

Jaime Delgadillo Velazquez ◽

Patricia Acosta Dominguez ◽

...

Keyword(s):

Skeletal Muscle ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Mexican Women ◽

Calf Circumference ◽

Consensus Definition ◽

European Consensus ◽

Skeletal Muscle Mass Index

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Appendicular skeletal muscle mass (ASMM) percentiles in 7489 healthy adults aged 18–98 years determined by bioelectrical impedance analysis (BIA)

Clinical Nutrition ◽

10.1016/s0261-5614(03)80003-1 ◽

2003 ◽

Vol 22 ◽

pp. S1 ◽

Cited By ~ 1

Author(s):

U.G. Kyle ◽

Y.M. Dupertuis ◽

C.A. Raguso ◽

D. Hans ◽

C. Pichard

Keyword(s):

Skeletal Muscle ◽

Muscle Mass ◽

Bioelectrical Impedance Analysis ◽

Skeletal Muscle Mass ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

Healthy Adults ◽

Appendicular Skeletal Muscle ◽

Appendicular Skeletal Muscle Mass

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Alternate Mediterranean diet score is positively associated with skeletal muscle mass index in middle-aged adults

British Journal Of Nutrition ◽

10.1017/s0007114517001118 ◽

2017 ◽

Vol 117 (8) ◽

pp. 1181-1188 ◽

Cited By ~ 9

Author(s):

Hui-yuan Tian ◽

Rui Qiu ◽

Li-peng Jing ◽

Zhan-yong Chen ◽

Geng-dong Chen ◽

...

Keyword(s):

Skeletal Muscle ◽

Mediterranean Diet ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

General Information ◽

Whole Body ◽

Cross Sectional ◽

Mediterranean Diet Score ◽

Skeletal Muscle Mass Index ◽

Diet Score

AbstractResearches have suggested Mediterranean diet might lower the risk of chronic diseases, but data on skeletal muscle mass (SMM) are limited. This community-based cross-sectional study examined the association between the alternate Mediterranean diet score (aMDS) and SMM in 2230 females and 1059 males aged 40–75 years in Guangzhou, China. General information and habitual dietary information were assessed in face-to-face interviews conducted during 2008–2010 and 3 years later. The aMDS was calculated by summing the dichotomous points for the items of higher intakes of whole grain, vegetables, fruits, legumes, nuts, fish and ratio of MUFA:SFA, lower red meat and moderate ethanol consumption. The SMM of the whole body, limbs, arms and legs were measured using dual-energy X-ray absorptiometry during 2011–2013. After adjusting for potential covariates, higher aMDS was positively associated with skeletal muscle mass index (SMI, SMM/height2, kg/m2) at all of the studied sites in males (all Ptrend<0·05). The multiple covariate-adjusted SMI means were 2·70 % (whole body), 2·65 % (limbs), 2·50 % (arms) and 2·70 % (legs) higher in the high (v. low) category aMDS in males (all P<0·05). In females, the corresponding values were 1·35 % (Ptrend=0·03), 1·05, 0·52 and 1·20 %, (Ptrend>0·05). Age-stratified analyses showed that the favourable associations tended to be more pronounced in the younger subjects aged less than the medians of 59·2 and 62·2 years in females and males (Pinteraction>0·10). In conclusion, the aMDS shows protective associations with SMM in Chinese adults, particularly in male and younger subjects.

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