scholarly journals Autonomic modulation at rest and in response to postural change in adolescents with Duchenne muscular dystrophy: a cross-sectional study

2021 ◽  
Vol 79 (9) ◽  
pp. 766-773
Author(s):  
Mariana Viana Rodrigues ◽  
Mileide Cristina Stoco-Oliveira ◽  
Talita Dias da Silva ◽  
Celso Ferreira ◽  
Heloisa Balotari Valente ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Oxygen Saturation ◽  
Cross Sectional Study ◽  
Control Group ◽  
Autonomic Modulation ◽  
Postural Change ◽  
Cross Sectional

ABSTRACT Background: Analysis of autonomic modulation after postural change may inform the prognosis and guide treatment in different populations. However, this has been insufficiently explored among adolescents with Duchenne muscular dystrophy (DMD). Objective: To investigate autonomic modulation at rest and in response to an active sitting test (AST) among adolescents with DMD. Methods: Fifty-nine adolescents were included in the study and divided into two groups: 1) DMD group: adolescents diagnosed with DMD; 2) control group (CG): healthy adolescents. Participants’ weight and height were assessed. Lower limb function, motor limitations and functional abilities of the participants in the DMD group were classified using the Vignos scale, Egen classification and motor function measurement, respectively. The following variables were assessed before, during and after AST: systolic blood pressure (SBP), diastolic blood pressure (DBP), respiratory rate (f), oxygen saturation and heart rate (HR). To analyze the autonomic modulation, the HR was recorded beat-by-beat. Heart rate variability (HRV) indices were calculated in the time and frequency domains. Results: Differences in relation to groups were observed for all HRV indices, except LF/HF, oxygen saturation, HR and f (p < 0.05). Differences in relation to time and the interaction effect between group and time were observed for RMSSD, SD1, SD2, SD1/SD2, LFms2 and LFnu, HFun, SBP and DBP (p < 0.05). Differences in relation to time were also observed for the indice SDNN, FC and f (p < 0.05). Conclusions: Performing the AST promoted reduced autonomic modulation and increased SBP, DBP and HR in adolescents with DMD.

scholarly journals Influence of Different Types of Corticosteroids on Heart Rate Variability of Individuals with Duchenne Muscular Dystrophy—A Pilot Cross Sectional Study

Life ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 752
Author(s):  
Rodrigo Martins Dias ◽  
Rosangela Akemi Hoshi ◽  
Luiz Carlos Marques Vanderlei ◽  
Carlos Bandeira de Mello Monteiro ◽  
Mayra Priscila Boscolo Alvarez ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cross Sectional Study ◽  
Control Group ◽  
Autonomic Modulation ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cardiac Autonomic Modulation

Individuals with Duchenne Muscular Dystrophy (DMD) have an impairment of cardiac autonomic function categorized by parasympathetic reduction and sympathetic predominance. The objective of this study was to assess the cardiac autonomic modulation of individuals with DMD undergoing therapy with Prednisone/Prednisolone and Deflazacort and compare with individuals with DMD without the use of these medications and a typically developed control group. Methods: A cross-sectional study was completed, wherein 40 boys were evaluated. The four treatment groups were: Deflazacort; Prednisone/Prednisolone; no corticoid use; and typical development. Heart Rate Variability (HRV) was investigated via linear indices (Time Domain and Frequency Domain) and non-linear indices Results: The results of this study revealed that individuals with DMD undertaking pharmacotherapies with Prednisolone demonstrated HRV comparable to the Control Typically Developed (CTD) group. In contrast, individuals with DMD undergoing pharmacotherapies with Deflazacort achieved lower HRV, akin to individuals with DMD without any medications, as demonstrated in the metrics: RMSSD; LF (n.u.), HF (n.u.), LF/HF; SD1, α1, and α1/α2, and a significant effect for SD1/SD2; %DET and Ratio; Shannon Entropy, 0 V%, 2 LV% and 2 ULV%. Conclusions: Corticosteroids have the potential to affect the cardiac autonomic modulation in adolescents with DMD. The use of Prednisone/Prednisolone appears to promote improved responses in terms of sympathovagal activity as opposed to Deflazacort.

scholarly journals Parkinson's disease effect on autonomic modulation: an analysis using geometric indices

2021 ◽  
Vol 79 (2) ◽  
pp. 114-121
Author(s):  
Mileide Cristina Stoco-Oliveira ◽  
Ana Laura Ricci-Vitor ◽  
Laís Manata Vanzella ◽  
Heloisa Balotari Valente ◽  
Vitor Eduardo dos Santos Silva ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Heart Rate ◽  
Parkinson's Disease ◽  
Cross Sectional Study ◽  
Control Group ◽  
Autonomic Modulation ◽  
Poincaré Plot ◽  
Cross Sectional ◽  
Rr Intervals ◽  
Geometric Methods

ABSTRACT Background: Parkinson's disease (PD) produces autonomic changes, indicating lower parasympathetic modulation and global variability, but these changes need further studying regarding geometric methods. Objective: To investigate the autonomic modulation in individuals with PD using heart rate variability (HRV) indices obtained through geometric methods. Methods: This is a cross-sectional study that assessed 50 individuals, split into two groups: PD group (PDG; n=26; 75.36±5.21 years) and control group (CG; n=24; 75.36±5.21 years). We evaluated the autonomic modulation by measuring the heart rate beat-to-beat for 30 min with the individual in supine rest using a heart rate monitor and assessed geometric indices (RRtri, TINN, SD1, SD2, SD1/SD2 ratio, and qualitative analysis of the Poincaré plot). Results: Significant reductions were found in RRtri, TINN, SD1, and SD2 indices among PDG compared to CG. Regarding the SD1/SD2 ratio, no significant changes were detected between the groups. The Poincaré plot demonstrated that individuals with PD had lower beat-to-beat dispersion in RR intervals, in addition to greater long-term dispersion of RR intervals compared to CG. Conclusions: The results suggest a reduction in the parasympathetic autonomic modulation and global variability in individuals with PD compared to controls, regardless of sex, age, and body mass index.

scholarly journals Heart rate variability and blood pressure among Japanese men and women: a community-based cross-sectional study

2014 ◽  
Vol 37 (8) ◽  
pp. 779-784 ◽  
Author(s):  
Hiromi Mori ◽  
Isao Saito ◽  
Eri Eguchi ◽  
Koutatsu Maruyama ◽  
Tadahiro Kato ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Japanese Men ◽  
Men And Women

scholarly journals The Physiological Effects of IPAD Digital Games on Children with Autism

2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Nur Zakiah Mohd Saat ◽  
Najwa Suhaili Md Zin ◽  
Sazlina Kamaralzaman
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Children With Autism ◽  
Cross Sectional Study ◽  
Breathing Rate ◽  
Blood Pressure Monitor ◽  
Pressure Monitor ◽  
Cross Sectional ◽  
Strategy Games ◽  
The Mean

Background: Previous studies found that the use of an iPad® in intervention programmes benefited the skills of daily living of children with autism. The purpose of the study was to determine the physiological changes in children while playing action and strategy games on an iPad. Methodology: A cross-sectional study was conducted using Powerlab 24/6T, a blood pressure monitor, respiratory belt, and finger pulse transducer. The children were asked to play two types of game. The duration for each game was 10 minutes. The measurement of blood pressure - both systolic and diastolic, heart rate and breathing rate were taken at three consecutive times (before, during and after each game). The inclusion criteria are children aged 7 to 12 years old who have been diagnosed with a mild type of autism (Pervasive developmental disorder). The exclusion criteria were children who had co-morbidities such as epilepsy, migraine, heart, and lung problems, depression, physical disabilities and visual impairments.  Results: Nineteen children with autism participated in this study. The result indicated that the mean systolic and diastolic blood pressures increased before and after playing strategy games and action games. However, compared to pre-play values, the mean heart rate and breathing rate decreased both during and after playing both types of game. Meanwhile, there was significant mean difference for breathing rate for both types of game (p<0.05). Conclusion: Playing strategy and action games did not affect the measured physiological parameters of children with autism. 

scholarly journals The burden of Duchenne muscular dystrophy: An international, cross-sectional study

Neurology ◽  
2014 ◽  
Vol 83 (6) ◽  
pp. 529-536 ◽  
Author(s):  
E. Landfeldt ◽  
P. Lindgren ◽  
C. F. Bell ◽  
C. Schmitt ◽  
M. Guglieri ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Resting heart rate variability in regular yoga practitioners - A cross-sectional study

2020 ◽  
Vol 4 (2) ◽  
pp. 12-17
Author(s):  
Selvakumar Subash ◽  
Manikandan Sathiyaseelan ◽  
Dayanalakshmi Ramachandran
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Non Invasive ◽  
Yoga Group ◽  
Increased Risk ◽  
Resting Heart Rate Variability ◽  
Yoga Practitioners

Heart rate variability (HRV) is a useful and powerful non-invasive tool for quantitative assessment of cardiac autonomic function. Recent studies have shown that low heart rate variability is an indication of increased risk for cardiac diseases and sudden cardiac death. Yoga has been associated with improved cardio-respiratory performance. Thirty male regular yoga practitioners doing yoga for more than 3 years, age between 25-45 years (yoga group) and 30 male non-yoga practitioners, age-matched (control group) were included. A computerized Niviqure ECG system with HRV software was used for heart rate variability recording. Our results show that frequency-domain parameters like LF power, LF n.u, and LF/HF ratio were significantly lower in yoga group compared to control group. Time-domain parameters like mean RR, NN50, pNN50 were significantly higher in yoga group compared to control group. We conclude that the yoga increases heart rate variability by optimizing the autonomic functions, which is a good indicator of cardiac autonomic activity during rest.

scholarly journals Evaluation of speed-accuracy trade-off in a computer task to identify motor difficulties in individuals with Duchenne Muscular Dystrophy - A cross-sectional study

2020 ◽  
Vol 96 ◽  
pp. 103541
Author(s):  
Talita Dias da Silva ◽  
Denise Cardoso Ribeiro-Papa ◽  
Shelly Coe ◽  
Silvia Regina Pinheiro Malheiros ◽  
Thais Massetti ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Trade Off ◽  
Motor Difficulties ◽  
Speed Accuracy
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