scholarly journals Canine ovarian dysgerminoma

2020 ◽  
Vol 50 (1) ◽  
Author(s):  
Florencia Sollier Podestá ◽  
Daniela Izquierdo Caquias
Keyword(s):  
Clinical Case ◽  
Clinical Signs ◽  
Definitive Diagnosis ◽  
Cell Tumor ◽  
Pathological Findings ◽  
Hormonal Imbalance ◽  
Persistent Estrus ◽  
Ovarian Dysgerminoma ◽  
Low Incidence ◽  
English Bulldog

ABSTRACT: This research aimed to describe a clinical case of ovarian dysgerminoma in a bitch, by showing clinical, ultrasound, surgical and pathological findings. The research also sought to emphasize the importance of establishing an early and definitive diagnosis through histopathology, establishing appropriate protocols for each patient. Ovarian tumors have a low incidence in dogs and cats. Dysgerminomas are a type of ovarian germ cell tumor. They develop in dogs of variable age, that may present clinical signs of hormonal imbalance such as persistent estrus, or pyometra. Prognosis is good in animals that undergo surgery and show no evidence of metastasis. This article presents a clinical case of a 6-year-old English Bulldog with persistent estrus for 2 months, and slightly depressed mental state. Ultrasound revealed the presence of a mass on the left ovary and uterine content. Ovariohysterectomy was performed and the mass was submitted to histopathological exam, which diagnosed an ovarian dysgerminoma.

scholarly journals Clinicopathological and immunohistochemical evaluation of oesophageal leiomyosarcoma in a dog

2015 ◽  
Vol 45 (9) ◽  
pp. 1644-1647 ◽  
Author(s):  
Renata Cintra Ciccone Alves ◽  
Tatiana Linardi Batista ◽  
Renée Laufer-Amorim ◽  
Fabiana Elias ◽  
Sabryna Gouveia Calazans ◽  
...  
Keyword(s):  
Clinical Signs ◽  
Malignant Neoplasm ◽  
Definitive Diagnosis ◽  
Radiographic Examination ◽  
Muscle Fibres ◽  
Immunohistochemical Examination ◽  
Intact Male ◽  
Low Incidence ◽  
Thoracic Oesophagus ◽  
Severe Dyspnoea

<p>Oesophageal leiomyosarcoma is a malignant neoplasm of smooth muscle fibres that is infrequently reported in the literature. Because of the importance of definitive diagnosis and the low incidence of this tumour in dogs, it was reported a case of oesophageal leiomyosarcoma in a dog. A 13-year-old intact male Rottweiler presented regurgitation, hyporexia, and chronic weight loss. After an imaging examination, tumour in the thoracic oesophagus was suspected and a biopsy was sugested for definitive diagnosis. However, the owner did not permit the procedure. Six months after the clinical diagnosis, the patient was brought for evaluation of anorexia, apathy, and severe dyspnoea. Because of the patient's clinical signs and lack of response to emergency treatment, he was euthanized. Upon necropsy, it was identified the neoplastic formation, previously identified in the radiographic examination in the thoracic oesophagus, near the diaphragm. Histopathology revealed a proliferation of mesenchymal cells, and the diagnosis of leiomyosarcoma was confirmed by immunohistochemical examination. Despite the low incidence of oesophageal leiomyosarcoma, it should be included as a differential diagnosis for animals with chronic regurgitation.</p>

Thyroidectomy in a patient with a giant multinodular nontoxic cervical retrosternal goiter

2020 ◽  
pp. 97-99
Author(s):  
U. V. Kukhtenko ◽  
O. A. Kosivtsov ◽  
L. A. Ryaskov ◽  
E. I. Abramian
Keyword(s):  
Surgical Treatment ◽  
Clinical Case ◽  
Clinical Signs ◽  
Disease Relapse ◽  
Cardiac Pathology ◽  
Nontoxic Goiter ◽  
Retrosternal Goiter

A clinical case of successful surgical treatment of a patient with a giant cervical retrosternal nontoxic goiter with severe cardiac pathology is presented. Thyroidectomy from cervical access without sternotomy was performed. At the follow-up examination 5 months after the operation, instrumental and clinical signs of disease relapse were not detected.

Serum cobalamin concentrations and small intestinal ultrasound changes in 75 cats with clinical signs of gastrointestinal disease: a retrospective study

2016 ◽  
Vol 19 (1) ◽  
pp. 48-56 ◽  
Author(s):  
Maria C Jugan ◽  
John R August
Keyword(s):  
Small Intestine ◽  
Gastrointestinal Disease ◽  
Clinical Signs ◽  
Small Animal ◽  
Abdominal Ultrasound ◽  
Wall Layer ◽  
Normal Serum ◽  
Definitive Diagnosis ◽  
Albumin Concentration ◽  
Small Intestinal

Objectives The aim of the study was to evaluate ultrasonographic changes in the small intestine of cats with clinical signs of gastrointestinal disease and low or low–normal serum cobalamin concentrations. Methods Records for client-owned cats presenting to the small animal hospital with signs of gastrointestinal disease and in which serum cobalamin concentrations were measured from 2000–2013 were reviewed. Inclusion criteria were cobalamin concentrations <500 ng/l, abdominal ultrasound within 1 month of cobalamin testing and definitive diagnosis. Results Of 751 serum cobalamin measurements, hypocobalaminemia or low–normal cobalamin was identified in 270 cats, abdominal ultrasound was performed in 207 of those cats and a diagnosis was available for 75 of them. Small intestinal ultrasound changes were detected in 49/75 (65%) cats. Abnormalities included thickening, loss of wall layer definition, echogenicity alterations and discrete masses. Serum cobalamin concentrations <500 ng/l were observed with diagnoses of inflammatory disease, neoplasia, infectious disease and normal histopathology. Cobalamin concentration was significantly lower in cats with lymphoma or inflammatory bowel disease compared with other gastrointestinal neoplasia ( P = 0.031). No difference was found between cobalamin concentration and the presence of ultrasound abnormalities, specific ultrasound changes or albumin concentration. Conclusions and relevance One-third of symptomatic cats with hypocobalaminemia or low–normal cobalamin concentrations may have an ultrasonographically normal small intestine. For the majority of cats in this study, histopathologic abnormalities were observed in the small intestine, regardless of ultrasound changes. These findings suggest gastrointestinal disease should not be excluded based on low–normal cobalamin concentrations, even with a concurrent normal ultrasound examination. Additional studies are needed in cats with low–normal serum cobalamin concentrations, as a definitive diagnosis was not pursued consistently in those cats. However, data from this study suggest that careful monitoring, histopathologic evaluation and future cobalamin supplementation may be warranted.

Giant Cell Tumor of the Talar Neck

2007 ◽  
Vol 97 (3) ◽  
pp. 225-228 ◽  
Author(s):  
Hakan Selek ◽  
Hamza Özer ◽  
Sacit Turanli ◽  
Özlem Erdem
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Clinical Signs ◽  
Cell Tumor ◽  
Giant Cell Tumors ◽  
Radiographic Appearance ◽  
Aneurysmal Bone Cysts ◽  
Tumors Of Bone ◽  
Brown Tumors ◽  
Small Bones

We describe a patient with a giant cell tumor in the talar head and neck of the left foot who was diagnosed as having osteochondritis dissecans and treated with arthroscopic drilling in this same location 3 years earlier. Giant cell tumors can be confused with several conditions, including giant cell reparative granulomas, brown tumors, and aneurysmal bone cysts. Giant cell tumors of bone typically occur in the epiphysis of long bones, including the distal femur and proximal tibia. They are uncommonly found in the small bones of the foot or ankle, and talar involvement is rare. Despite this rarity, the radiographic appearance and clinical signs of talar lesions should be considered in the differential diagnosis of nontraumatic conditions in the foot. (J Am Podiatr Med Assoc 97(3): 225–228, 2007)

Hormone-producing ovarian tumors in children (a clinical case of managing a patient with a granulosa cell tumor of the juvenile type)

2021 ◽  
Vol 27 (5) ◽  
pp. 48
Author(s):  
L.V. Adamyan ◽  
E.V. Sibirskaya ◽  
S.A. Korotkova ◽  
E.A. Karapetyan ◽  
E.I. Polyakova ◽  
...  
Keyword(s):  
Granulosa Cell ◽  
Clinical Case ◽  
Granulosa Cell Tumor ◽  
Cell Tumor ◽  
Ovarian Tumors ◽  
Juvenile Type

Multiple causes for rhinolithiasis

2014 ◽  
Vol 52 (2) ◽  
pp. 183-186
Author(s):  
T. Send ◽  
M. Jakob ◽  
K.W.G. Eichhorn
Keyword(s):  
Nasal Cavity ◽  
Foreign Bodies ◽  
Clinical Symptoms ◽  
Pathological Findings ◽  
Common Cause ◽  
Clinical Pattern ◽  
Ectopic Tooth ◽  
Low Incidence ◽  
Iatrogenic Origin ◽  
Endotracheal Anesthesia

Background: Rhinoliths are rare affections of the main nasal cavity and the paranasal sinuses. Initially, as a result of their low incidence, they are often incorrectly classified as calcified tumors in clinical examination. Methodology: We have identified three cases in our patient population and evaluated the clinical symptoms as well as the pathological findings and the causes of the disease. Results: Due to their extension and the respective clinical pattern, all masses were surgically removed under endotracheal anesthesia. The histopathological findings comprised an ectopic tooth, a vegetable (most likely a leaf from the garden) as well as a textile foreign body (probably of iatrogenic origin). Conclusion: Undiscovered foreign bodies of the main nasal cavity are a common cause for the formation of rhinoliths. We have also displayed the respective incidence and the therapeutic options.

scholarly journals А сlinical case report of mediastinal teratoma in an adolescent patient with Klinefelter syndrome

2020 ◽  
Vol 19 (4) ◽  
pp. 143-149
Author(s):  
S. S. Saliyeva ◽  
R. Z. Boranbayeva ◽  
B. M. Zhumadullayev ◽  
K. E. Khairov ◽  
E. V. Krivenko ◽  
...  
Keyword(s):  
Clinical Case ◽  
Multidisciplinary Approach ◽  
Klinefelter Syndrome ◽  
Malignant Tumors ◽  
Complete Removal ◽  
Cell Tumor ◽  
Growing Teratoma Syndrome ◽  
Mediastinal Teratoma ◽  
Mature Type ◽  
Derivatives Of

Teratoma is a germ cell tumor, which consists of derivatives of three germ layers and has various malignant potentials – from benign mature forms to immature embryonic forms with a somatic type of malignancy. Even the mature type of teratoma is biologically unpredictable providing for an ability to grow locally with invasion. Necessity for complete removal of tumors, wherever they are located, is explained by the fact that there is a risk of a possible development of growing teratoma syndrome or transformation into malignant tumors. This article describes the clinical case of growing teratoma syndrome of mediastinal localization in a teenager with Klinefelter syndrome, also as an example of the multidisciplinary approach of pediatric oncologists, surgeons, radiotherapists and pathomorphologists in decision-making for optimal treatment. The patients' parents gave their consent to the use of their child's data, including photographs, for research purposes and in publications.

scholarly journals Paediatric Hypophosphatasia in Real-Life Clinical Practise.

Doctor Ru ◽  
2020 ◽  
Vol 19 (10) ◽  
pp. 57-60
Author(s):  
A.V. Vitebskaya ◽  
◽  
Chernova E.V. Chernova ◽  
Keyword(s):  
Alkaline Phosphatase ◽  
Clinical Case ◽  
Clinical Signs ◽  
Real Life ◽  
Compound Heterozygous Mutation ◽  
Heterozygous Mutation ◽  
Compound Heterozygous ◽  
Milk Teeth ◽  
Motor Retardation ◽  
Gait Disturbances

Objective of the Paper: to describe a clinical case of paediatric hypophosphatasia (HPP) and identify clinical signs, most characteristic of the paediatric HPP form. Key Points. HPP is an congenital rickets-like disease caused by reduced activity of tissue-nonspecific alkaline phosphatase (ALP). According to the time of manifestation, there are perinatal, infant, paediatric, and adult HPPs. The article describes a clinical case of paediatric HPP in a 3.5-year old boy. HPP was diagnosed due to reduced ALP and characteristic X-ray findings. The diagnosis was confirmed with DNA testing: compound heterozygous mutation in с.571 G>A/с.144_148dup of ALPL was found. Conclusion. Typical findings in paediatric HPP are growth retardation and muscular hypotonia, motor retardation; gait disturbances, myalgia, marked fatigue causing limited period of walking; rachitic deformations, premature loss of milk teeth with unchanged roots, respiratory disturbances, and frequent bronchopulmonary disorders. Keywords: hypophosphatasia, children, alkaline phosphatase.

scholarly journals Dentinogenic Ghost Cell Tumor of the Peripheral Variant Mimicking Epulis

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Uddipan Kumar ◽  
Hitesh Vij ◽  
Ruchieka Vij ◽  
Jitin Kharbanda ◽  
IN Aparna ◽  
...  
Keyword(s):  
Microscopic Examination ◽  
Definitive Diagnosis ◽  
Cell Tumor ◽  
Current Concept ◽  
Odontogenic Tumor ◽  
Ghost Cell ◽  
Microscopic Appearance ◽  
Odontogenic Epithelium ◽  
Gingival Enlargement ◽  
Dentinogenic Ghost Cell Tumor

Dentinogenic ghost cell tumor (DGCT) is an uncommon locally invasive odontogenic tumor regarded by many as a variant of calcifying odontogenic cyst. The peripheral variant of this clinical rarity appears as a well-circumscribed mass mimicking a nonspecific gingival enlargement. Microscopic appearance of odontogenic epithelium admixed with focal areas of dentinoid formation and sheets of ghost cells giving the definitive diagnosis of dentinogenic ghost cell tumor imply that microscopic examination is compulsory for any gingival mass. Van Gieson histochemical stain further confirmed the nature of dentinoid-like material. A complete workup of a case of peripheral dentinogenic ghost cell tumor is presented in this paper and the current concept as well as the appraisal of literature is presented.

Clinical case of diagnosis of primary open-angle glaucoma in a patient after previously performed anterior radial keratotomy

2021 ◽  
pp. 126-131
Author(s):  
R.A. Burya ◽  
◽  
A.A. Fil ◽  
E.L. Sorokin ◽  
◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Clinical Case ◽  
Primary Open Angle Glaucoma ◽  
Low Vision ◽  
Open Angle Glaucoma ◽  
Clinical Signs ◽  
Primary Diagnosis ◽  
Applanation Tonometry ◽  
Open Angle ◽  
Radial Keratotomy

The article describes a clinical case of diagnosis and detection of primary open-angle glaucoma (POAG) in a patient after previously performed anterior dosed radial keratotomy (ADRK). The reasons that hampered the primary diagnosis of POAG in the presented patient at an outpatient appointment with an ophthalmologist were: inadequate assessment of the ratio of the state of the lenses and low vision; a falsely underestimated level of tonometric intraocular pressure (IOP), as well as the absence of an in-depth ophthalmoscopic assessment of the condition of the optic nerve head, failure to comply with the mandatory perimetric examination in such cases. It should be especially remembered that there is a high likelihood of underestimation of applanation tonometry indices after performing ADRK, therefore, the assessment of its results should be treated with caution, identifying other clinical signs characteristic of glaucoma. This will make it possible to diagnose glaucoma in time and prescribe pathogenetic treatment in a timely manner. Key words: anterior dosed radial keratotomy, primary open-angle glaucoma, intraocular pressure.

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