scholarly journals Key-Gaskell syndrome in Brazil: first case report

2014 ◽  
Vol 66 (4) ◽  
pp. 1046-1050
Author(s):  
B.B.J. Torres ◽  
G.C. Martins ◽  
P.E. Ferian ◽  
B.C. Martins ◽  
M.A. Rachid ◽  
...  

Feline dysautonomia is a devastating disease characterized by neuronal degeneration in autonomic ganglia that results in clinical signs related to dysfunction of the sympathetic and parasympathetic nervous systems. The cause is unknown and this disease has a poor prognosis and no definitive treatment. Most reports have been described in few countries around the world, but the prevalence may be underestimated in countries like Brazil. This study describes the progression and clinicopathological changes of dysautonomia in a 17-month-old female Brazilian shorthair cat.

2014 ◽  
Vol 59 (No. 3) ◽  
pp. 137-140 ◽  
Author(s):  
P. Melkova ◽  
P. Cizek ◽  
E. Ludvikova ◽  
B. Bezdekova

Equine grass sickness (EGS) is a degenerative polyneuropathy affecting postganglionic parasympathetic and sympathetic neurons. The major clinical signs relate to dysfunction of the gastrointestinal tract and the condition is frequently fatal. EGS has been reported in different parts of the world including Europe. This paper describes the first case of equine dysautonomia in the Czech Republic. The ante mortem diagnosis was based on typical clinical signs and a positive phenylephrine eye-drop test and was confirmed at necropsy following observation of pathognomic histopathological lesions in the enteric neural system of the ileum.  


2019 ◽  
Vol 71 (4) ◽  
pp. 1327-1330
Author(s):  
L.F.A. Toledo ◽  
H.L. Jerdy ◽  
P.C.A.R. Silva ◽  
E.C.Q. Carvalho ◽  
D.A.B. Lessa

ABSTRACT A 12-month-old mule (sterile hybrid equine species) presented unspecific neurological changes (symmetric ataxia, dysmetria, conscious proprioceptive deficit and weakness). Due to poor prognosis and to the fact that a sibling from the previous generation exhibited similar clinical signs that were not definitively diagnosed, the animal was euthanized. Diagnosis of neuroaxonal dystrophy was confirmed by anatomohistopathological analysis. This is the first clinical case of neuronal dystrophy in a mule reported in the world. The clinical and histopathological characteristics of this disease were very similar to those reported for several equine breeds. Therefore, the disease should also be considered in the diagnosis of neurological conditions in mules and donkeys.


2021 ◽  
pp. 797-801
Author(s):  
Quang Tien Nguyen ◽  
Anh Tuan Pham ◽  
Thuy Thi Nguyen ◽  
Tam Thi Thanh Nguyen ◽  
Ky Van Le

Pulmonary angiosarcoma is a rare clinical entity with a poor prognosis and no established therapeutic strategies. We present the first case to our knowledge of metastatic pulmonary angiosarcoma, treated with checkpoint inhibitor immunotherapy, and have an excellent response. Until now, patient has been treated with immunotherapy for 1 year, and his disease is stable and well-tolerated.


2017 ◽  
Vol 69 (5) ◽  
pp. 1067-1072
Author(s):  
C.A. Castillo ◽  
C. Jaramillo ◽  
M.J. Loaiza ◽  
R. Blanco

ABSTRACT The equine metabolic syndrome is a condition that can be recognized because of obesity, insulin resistance and laminitis. Genetic factors could play a role in the occurrence of this syndrome. Certain breeds such as ponies (including the South American creole horses) have a lower sensibility to insulin and a higher prevalence of hyperinsulinemia. The environment and management conditions, such as overfeeding and lack of exercise are factors that bring a propensity for obesity. The adipose tissue works as an endocrine organ producing hormones (adipokines or adipocytokines) that affect the horse´s metabolism. The objective of this report is to describe the first case report of a Colombian creole mare with a metabolic syndrome, diagnosed by means of the combined test of glucose-insulin and clinical signs. Early diagnosis of this entity and an adequate treatment are useful for improving the life and the zootechnical conditions of the patient.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1982891
Author(s):  
Miguel Angel Moyón Constante ◽  
Fernando Xavier Moyón Constante ◽  
Jorge Fernando Tufiño ◽  
Andres Cárdenas Patiño ◽  
Gabriel Alejandro Molina ◽  
...  

Mixed adenoneuroendocrine carcinomas are rare tumors that contain both an exocrine and an endocrine component. Since the latest classification by the World Health Organization and with the aid of immunostaining, more mixed adenoneuroendocrine carcinomas are now identified and diagnosed. Nonetheless, our knowledge of these tumors is still limited, notably concerning gastric variants, as the cases reported in the literature are very limited. The clinical and surgical treatment, including the chemotherapy schemes, the prognosis, and recurrence still represent challenges for the medical teams. We present the case of a 62-year-old woman. After an upper endoscopy revealed multiple polyps and a low-grade neuroendocrine tumor, a D2 radical gastrectomy was performed. A low output esophageal anastomotic leak was discovered in the postoperative period and successfully managed. Pathology revealed a gastric mixed adenoneuroendocrine carcinoma, the first case of this kind reported in Ecuador. Patient is doing well and under constant surveillance up until her 13th postoperative month.


2013 ◽  
Vol 5 (2) ◽  
pp. 12 ◽  
Author(s):  
Andrea Santos Lima ◽  
Maria Madileuza Carneiro Neves ◽  
Karen Machado Gomes ◽  
Klarissa Miranda Guarines ◽  
Carlos Feitosa Luna ◽  
...  

<em>Mycobacterium wolinskyi</em> is a rapidly growing mycobacterium, first described in 1999 as a member of the group <em>Mycobacterium smegmatis</em> (<em>Mycobacterium smegmatis</em>, <em>Mycobacterium wolinskyi</em> and <em>Mycobacterium goodii</em>). Only 19 case reports all over the world have been described on literature, none of them in Brazil. On this report, it is described one case of infection after a mammoplasty procedure performed in a private health service in the county of Recife, Pernambuco, Brazil, in 2009. The mycobacteria specie was identified using biochemical tests and sequencing the specific gene <em>rpoB</em>. To treat the infection by <em>Mycobacterium wolinskyi</em> it was necessary to combine antibiotics for a long period of time associated with surgical procedures of the breast abscesses.


2017 ◽  
Vol 53 (5) ◽  
pp. 277-280
Author(s):  
Victoria Jenkins ◽  
Carlos Henrique de Mello Souza ◽  
Louis-Phillippe de Lorimier ◽  
Evandro de Toledo-Piza

ABSTRACT Squamous cell carcinoma of the penis was diagnosed by incisional biopsy of a penile mass in a 12 yr old intact male beagle dog presenting with hemorrhagic discharge from the prepuce. Penile amputation, orchiectomy with scrotal ablation, and scrotal urethrostomy were performed. Hypertrophic osteopathy secondary to pulmonary metastatic disease occurred 10 mo after the surgery. Palliative treatment with piroxicam was administered and led to complete resolution of the clinical signs of the pain. Sixteen months following surgery, the dog presented with significant dyspnea and anorexia and was euthanized due to poor prognosis. This case report describes a rare penile tumor, squamous cell carcinoma. Consequent paraneoplastic hypertrophic osteopathy and its palliative treatment are also reviewed.


Author(s):  
Seyed Sajjad Hasheminasab ◽  
Hadi Mohamadi Talvar ◽  
Ian Wright

Oestrus ovis larvae, Linnaeus 1761 (Diptera: Oestridae) are obligatory parasites of the nasal cavity and sinuses of sheep and goats in many parts of the world. After inspection of a slaughtered goat in Kalat Naderi region in Mashhad (East of Iran) in 2012, 25 larvae were observed within the horns without any larvae being present in the sinuses. The larvae were identified morphologically as those of Oestrus ovis. Oestrosis is a widespread myiasis which may severely impair the health of small ruminants. Oestrus ovis larvae are also responsible for causing human ophthalmomyiasis, and this infection is often misdiagnosed as acute conjunctivitis. Oestrus ovis is an economically important parasite of nasal cavities and the adjoining sinuses in sheep and goats worldwide. It causes losses in meat, wool and milk production. To the author’s knowledge, this is the first recorded case of horn infestation in goats by the larvae of Oestrus ovis in Iran without the sinuses being affected.


2013 ◽  
Vol 82 (3) ◽  
pp. 249-252
Author(s):  
Valent Ledecký ◽  
Viera Revajová ◽  
Ľubomír Páleník ◽  
Mária Kuricová ◽  
Igor Capík ◽  
...  

The aim of this report was to present a clinical case and diagnostics of intrathoracic bone cyst as well as successful outcome of the surgical treatment in a male, 3-year-old West Highland White Terrier dog, weighing 6.9 kg. The dog was admitted in a very poor condition with clinical signs of severe dyspnoea that developed during about one month period of time before admission to our clinic. The dog underwent physical examination and further examinations including radiological examination which revealed a radiopaque mass formation in the cranial mediastinum. Ultrasonographic examination showed the presence of fluid; following thoracentesis revealed pseudochylous fluid. The bone cyst was surgically removed and more than 10 months after surgery the dog’s health was very good without any difficulties. Bone cysts in dogs are infrequent; this was the first case at our clinic and presented a successful treatment.


Author(s):  
Deniz Sirinoglu ◽  
Buse Sarigul ◽  
Ozan Baskurt ◽  
Mehmet Volkan Aydin

Abstract Background Primary spinal glioblastoma is a rare lesion which constitutes only 1.5% of all spinal tumors. Diagnosis is challenging due to absence of any radiological hallmark of the disease. Even though surgery combined with chemoradiotherapy is the optimal management for these tumors, prognosis is still poor. Dissemination of glioblastoma is reported several times in the literature, which is correlated with worse prognosis and outcome. This case report that we are presenting is the first case where dissemination of primary spinal glioblastoma dissemination is limited only to spinal cord, without intracranial invasion, and regression was achieved with chemoradiotherapy. Case Report In this article, a patient with primary spinal glioblastoma who presented with paraparesia is presented. Patient underwent surgery for resection of the tumor and received adjuvant radiotherapy. However, 9 months postoperatively, dissemination was detected in epidural and subdural spaces of spinal canal, with concomitant compression of spinal cord. There was no radiographically detected lesion in cranial MRI. He underwent second session of radiotherapy, combined with chemotherapy and steroid. Five months later, regression of metastatic disseminated lesions was observed. Conclusion Primary spinal glioblastoma is a rare pathology and known to have a poor prognosis, notably with dissemination of the disease. Even though further biomolecular studies are necessary to explain the pathophysiology better, chemotherapy and radiotherapy may be effective in regression of disseminated lesions.


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