scholarly journals Quality of life and functional capacity during the treatment of hematologic neoplasms

2018 ◽  
Vol 31 (0) ◽  
Author(s):  
Monique Vanderlinde de Souza ◽  
Marina Christofoletti ◽  
Anne Ribeiro Streb ◽  
Giovani Firpo Del Duca
Keyword(s):  
Quality Of Life ◽  
Functional Capacity ◽  
Daily Activities ◽  
Life Questionnaire ◽  
Role Functioning ◽  
Hematologic Neoplasms ◽  
Cross Sectional ◽  
European Organization ◽  
Instrumental Activities

Abstract Introduction: Cancer is a serious pathology with a high incidence and complex diagnoses. Emotional and environmental factors, the deleterious effects of these, and lifestyle affect different outcomes. Objective: Investigate the association between quality of life and functional capacity during treatment for hematologic cancer. Methods: A cross-sectional study with intentional sampling of patients of both sexes with hematologic neoplasms, interviewed in 2016. Quality of life (QF) was measured by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire. For the definition of functional capacity in basic and instrumental activities of daily life, the Katz Index and the Lawton Scale, respectively, were used. Data were analyzed by correlations and comparisons of means tests. Results: The 52 participants presented an average QF score of approximately 60.6. Among the functional scales, the worst result was in role functioning (46.8), while for symptoms, it was fatigue (48.1). The results of more expressive QF indicators were the strong correlation between role functioning and fatigue (r = -0.60), and a moderate correlation between social functioning and financial difficulties (r = -0.45). There was still an association between role functioning and functional incapacity in daily activities (p = 0.017). Fatigue was associated with incapacity for basic activities (p = 0.018), while insomnia was correlated with instrumental activities (p = 0.032). Conclusion: The association between lower QF scores and functional incapacity reflects the damaging effect of hematologic neoplasms on daily activities.

scholarly journals Quality of life of patients with lung cancer: A scoping review

2019 ◽  
Vol 22 (2) ◽  
Author(s):  
Rafael Turano Mota ◽  
Helder Márcio Ferreira Júnior ◽  
Fabiane Silva Pereira ◽  
Maria Aparecida Vieira ◽  
Simone de Melo Costa
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Scoping Review ◽  
Prospective Studies ◽  
Current Knowledge ◽  
Care Quality ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
European Organization

Abstract Objective: To characterize scientific publications on the quality of life of people with lung cancer in order to explore current knowledge of the subject, with emphasis on assessment instruments and methodological aspects. Method: A scoping type literature review was performed. Articles were sought in the databases of the Virtual Health Library, in an integrative manner, with the descriptors: Quality of life and Lung Neoplasms, with no date of publication or language restrictions (n=138). The selection of articles was based on inclusion and exclusion criteria defined in the study proposal. Results: We included 18 publications published between 2006 and 2017, the majority (n = 10) of which had a cross-sectional design. Eight different instruments were used to evaluate the quality of life of patients with lung cancer, four of which were specific for people with cancer. There was a prevalence of the use of the European Organization for Research and Treatment of Cancer Care Quality of Life Questionnaire - EORTC QLQ-C30 (n=8). Prospective studies (n=8) assessed quality of life before and after chemotherapy, physical therapy or pulmonary resection. The studies adopted different methodologies and provided conflicting results of quality of life. Cross-sectional studies with comparatively healthy subjects found an inferior quality of life for people with lung cancer. Conclusion: The scoping review contributed to the identification of the multiple evaluated instruments, both generic and specific. It found a lack of homogeneity in the methodological approaches of the studies. Further prospective studies with a specific instrument and methodological standardization to evaluate the quality of life of people with lung cancer are recommended.

scholarly journals Penilaian kualitas hidup penderita karsinoma nasofaring berdasarkan Karnofsky Scale, EORTC QLQ-C30 dan EORTC QLQ-H & N35

2014 ◽  
Vol 43 (2) ◽  
pp. 110
Author(s):  
Dewi Kurniawati ◽  
Frederik George Kuhuwael ◽  
Abdul Qadar Punagi
Keyword(s):  
Quality Of Life ◽  
Karnofsky Performance Scale ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
European Organization ◽  
Quality Of Life Questionnaire ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Performance Scale

Latar belakang: Karsinoma nasofaring (KNF) berpengaruh terhadap kualitas hidup penderita, baik dari kankernya sendiri, maupun pengobatan serta efek sampingnya. Penilaian kualitas hidup penderita KNF dapat secara unidimensional menggunakan parameter status tampilan Karnofsky Performance Scale (Karnofsky PS) atau multidimensional memakai parameter European Organization For Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQ-C30) dan European Organization For Research And Treatment Of Cancer Head and Neck Cancer Quality of Life Questionnaire (EORTC QLQ-H&N35).Tujuan: Menilai kesesuaian hasil skor Karnofsky PS, EORTC QLQ-C30 dan EORTC QLQ-H&N35 dalam menilai kualitas hidup penderita KNF dengan menentukan korelasi antar parameter dan menentukan estimasi skor Karnofsky PS menggunakan skor EORTC QLQ-C30 dan skor EORTC QLQ-H&N35. Menganalisis hubungan antar parameter menurut stadium.Metode: Penelitian adalah observasional analitik dengan pedekatan cross sectional. Populasinya semua kasus KNF yang berobat ke Bagian THT-KL, Rumah Sakit Wahidin Sudirohusodo, Makassar. Sampel sebanyak 48 orang dipilih secara purposive. Penilaian kualitas hidup menggunakan parameter Karnofsky PS, EORTC QLQ-C30 dan EORTC QLQ-H&N35. Hasil: Didapati kesesuaian hasil skor dari ketiga parameter, ditandai adanya korelasi bermakna antara skor Karnofsky PS, skor EORTC QLQ-C30 dan skor EORTC QLQ-H&N35. Semakin tinggi skor Karnofsky PS, akan semakin rendah skor EORTC QLQ-C30 dan skor EORTC QLQ-H&N35 maka kualitas hidup penderita KNF semakin baik. Skor EORTC QLQ-C30 dan skor EORTC QLQ-H&N35 dapat mengestimasi skor Karnofsky PS. Terdapat hubungan bermakna antara Karnofsky PS, EORTC QLQ-C30 dan EORTC QLQ-H&N35 menurut stadium (p<0,05). Kesimpulan: DEORTC QLQ-C30 dan EORTC QLQ-H&N35 dapat melengkapi Karnofsky PS dalam penilaian kualitas hidup penderita kanker kepala leher terutama KNF. Kata kunci: Kualitas hidup, KNF, Karnofsky PS, EORTC QLQ-C30, EORTC QLQ-H&N3.

scholarly journals Self-esteem and health-related quality of life in ostomized patients

2017 ◽  
Vol 70 (2) ◽  
pp. 271-278 ◽  
Author(s):  
Emmanuelle da Cunha Ferreira ◽  
Maria Helena Barbosa ◽  
Helena Megumi Sonobe ◽  
Elizabeth Barichello
Keyword(s):  
Quality Of Life ◽  
Global Health ◽  
Self Esteem ◽  
Life Questionnaire ◽  
Health Related Quality ◽  
Cross Sectional ◽  
European Organization ◽  
Related Quality ◽  
Health Related

ABSTRACT Objective: to assess self-esteem (SE) and health-related quality of life (HRQoL) in ostomized patients due to colorectal cancer. Method: cross sectional research with a quantitative approach. Three instruments were used for data collection: one instrument containing sociodemographic and clinical data, Rosenberg's Self-Esteem Scale, and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire. Results: SE and HRQoL were considered satisfactory. Significant statistical difference was found in the social function domain and marital status, ostomy duration, location, and time; global health scale and ostomy type; cognitive function and pain in the ostomy site. There was a correlation between self-esteem and all the functional scales and the global health scale. Conclusion: knowing SE and HRQoL levels, in addition to the variables that influence them, supports ostomized patients' care planning, rehabilitation, and social autonomy.

scholarly journals The burden of illness in patients with paroxysmal nocturnal hemoglobinuria receiving treatment with the C5-inhibitors eculizumab or ravulizumab: results from a US patient survey

2022 ◽  
Author(s):  
David Dingli ◽  
Joana E. Matos ◽  
Kerri Lehrhaupt ◽  
Sangeeta Krishnan ◽  
Michael Yeh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Burden Of Illness ◽  
Patient Survey ◽  
Life Questionnaire ◽  
Complement Protein ◽  
Cross Sectional ◽  
European Organization ◽  
Patient Reported

Abstract Paroxysmal nocturnal hemoglobinuria (PNH) is a rare and life-threatening disease with symptoms of hemolysis and thrombosis. Current therapies for this complement-mediated disease rely predominantly on inhibition of the C5 complement protein. However, data on treatment responses and quality of life in C5-inhibitor (C5i)-treated PNH patients are scarce. The objective of this study was to determine C5i treatment effects on clinical parameters, PNH symptoms, quality of life, and resource use for PNH patients. This cross-sectional study surveyed 122 individuals in the USA receiving treatment for PNH with C5-targeted monoclonal antibodies, eculizumab (ECU) or ravulizumab (RAV). Despite most patients receiving C5i therapy for ≥ 3 months (ECU 100%, n = 35; RAV 95.4%, n = 83), many patients remained anemic with hemoglobin levels ≤ 12 g/dL in 87.5% (n = 28/32) and 82.9% (n = 68/82) of ECU and RAV recipients, respectively. A majority of patients on ECU (88.6%; n = 31/35) and RAV (74.7%; n = 65/87) reported fatigue symptoms. Among PNH patients receiving C5i therapy for ≥ 12 months, some still reported thrombotic events (ECU, 10.0%, n = 1/10; RAV, 23.5%, n = 4/17) and required transfusions within the past year (ECU, 52.2%, n = 12/23; RAV, 22.6%, n = 7/31). Other patient-reported PNH symptoms included breakthrough hemolysis, shortness of breath, and headaches. Patients reported scores below the average population norms on the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) scales. Overall, this study found that PNH patients receiving ECU or RAV therapy demonstrated a significant burden of illness, highlighting the need for improved PNH therapies.

scholarly journals AVALIAÇÃO DA QUALIDADE DE VIDA DE ACOMETIDOS POR ACIDENTE VASCULAR ENCEFÁLICO ACOMPANHADOS POR UMA UNIDADE BÁSICA DE SAÚDE

2019 ◽  
Vol 4 (1) ◽  
pp. 44
Author(s):  
Bruno Nascimento da Silva ◽  
Emerson de Oliveira Ferreira ◽  
Lilian Cortez Sombra Vandesmet ◽  
Lara da Silva Nogueira ◽  
Sabrina Kécia de Freitas Almeida ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Capacity ◽  
Study Data ◽  
Life Questionnaire ◽  
Health Unit ◽  
Cross Sectional ◽  
Basic Health ◽  
Sf 36 ◽  
Cerebral Vascular

O Acidente Vascular encefálico (AVE) é determinado como uma afecção clínica que acontece de forma rápida e progressiva, causado pela interrupção súbita do fluxo sanguíneo ao encéfalo. Distingue-se em AVE Isquêmico e AVE Hemorrágico. Costuma-se dizer que os sobreviventes de AVE iniciam uma nova jornada na vida. Por essa razão, é fundamental a realização de estudos que abordem a qualidade de vida desses pacientes. Este trabalho teve como objetivo avaliar a qualidade de vida de acometidos por acidente vascular encefálico, atendidos na Unidade Básica de Saúde do Município de Capistrano-CE. É um estudo do tipo observacional e transversal, de caráter quantitativo e qualitativo. A coleta de dados foi de Janeiro a Maio de 2018. O instrumento utilizado foi o Questionário de Qualidade de Vida – SF-36. Os dados foram idade, acima de 60 anos (91%), sexo, os homens mais acometidos (55%), escolaridade, Ensino Fundamental Incompleto (50%), renda, salário mínimo 63,6%, AVEi com 72,7% e AVEh 27,3%. Foram avaliados os 8 domínios do questionário e calculada a média por domínio: CP = 16,8 LAF = 5,1 D = 57,6 EGS = 52,2 V = 42,5 AS = 48,8 LAE = 53,1 e SM = 64,1. Em relação ao questionário foi observado que os domínios com menor média foram Capacidade Funcional e Limitação por aspectos físicos isso devido as sequelas provenientes do AVE. Conclui-se que devido as várias limitações destes indivíduos é de suma importância o desenvolvimento de estratégias que visem minimizar as sequelas advindas da doença. EVALUATION OF QUALITY OF LIFE OF INDIVIDUALS SUFFERING FROM CEREBRAL VASCULAR ACCIDENTS ASSISTED BY A BASIC HEALTH UNIT ABSTRACT Cerebral Vascular Accident is determined as a clinical condition that occurs rapidly and progressively, caused by sudden interruption of blood flow to the brain. It distinguishes itself in Ischemic CVA and Hemorrhagic CVA. The objective of this study was to evaluate the quality of life of stroke survivors, assisted at a Basic Health Unit of the city of Capistrano-CE. It is a cross-sectional, observational, quantitative and qualitative study. Data collection was from January to May 2018. The instrument used was the Quality of Life Questionnaire - SF-36, in which each patient signed the Free and Informed Consent Term, as this work was approved by the ethics committee with the number: 2.698.166. The data were analyzed through the very method that the Questionnaire requires. The data took into account: age, over 60 years old (91%); sex, men most affected (55%); schooling, Incomplete Elementary School (50%); income, minimum wage of 63.6%, Ischemic CVA with 72.7% and Hemorrhagic CVA 27.3%. The 8 domains of the questionnaire were assessed and the average per domain was calculated: Functional Capacity = 16.8; Physical Limitation= 5.1; Pain = 57.6; General Health Status = 52.2; Vitality = 42.5; Social Aspects = 48.8; Emotional Limitation= 53.1; and Mental Health = 64.1. Regarding the questionnaire, it was observed that the domains with lower average were Functional Capacity and Limitation due to physical aspects resulting from the sequelae of CVA. It is concluded that due to the various limitations of these individuals, it is of utmost importance to develop strategies which aim at minimize the sequelae resulting from the disease.

scholarly journals The Health-Related Quality of Life of Sarcoma Patients and Survivors in Germany—Cross-Sectional Results of a Nationwide Observational Study (PROSa)

Cancers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3590 ◽  
Author(s):  
Martin Eichler ◽  
Leopold Hentschel ◽  
Stephan Richter ◽  
Peter Hohenberger ◽  
Bernd Kasper ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bone Sarcoma ◽  
Female Gender ◽  
Life Questionnaire ◽  
Health Related Quality ◽  
Cross Sectional ◽  
European Organization ◽  
Related Quality ◽  
Health Related

Sarcomas are rare cancers with high heterogeneity in terms of type, location, and treatment. The health-related quality of life (HRQoL) of sarcoma patients has rarely been investigated and is the subject of this analysis. Adult sarcoma patients and survivors were assessed between September 2017 and February 2019 in 39 study centers in Germany using standardized, validated questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30)). Associated factors were analyzed exploratively using multivariable linear regressions. Among 1113 patients, clinically important limitations and symptoms were most pronounced in emotional (63%, 95% CI 60–66%), physical (60%, 95% CI 57–62%), role functioning (51%, 95% CI 48–54%), and pain (56%, 95% CI 53–59%) and fatigue (51%, 95% CI 48–54%). HRQoL differed between tumor locations with lower extremities performing the worst and sarcoma types with bone sarcoma types being most affected. Additionally, female gender, higher age, lower socioeconomic status, recurrent disease, not being in retirement, comorbidities, and being in treatment were associated with lower HRQoL. Sarcoma patients are severely restricted in their HRQoL, especially in functioning scales. The heterogeneity of sarcomas with regard to type and location is reflected in HRQoL outcomes. During treatment and follow-up, close attention has to be paid to the reintegration of the patients into daily life as well as to their physical abilities and emotional distress.

scholarly journals Erectile dysfunction in male lymphoma survivors in a Southeast Asian country

2021 ◽  
Author(s):  
GG Gan ◽  
DLC Ng ◽  
YC Leong
Keyword(s):  
Quality Of Life ◽  
Erectile Dysfunction ◽  
Asian Country ◽  
Anxiety And Depression ◽  
Life Questionnaire ◽  
Sexually Active ◽  
Cross Sectional ◽  
European Organization ◽  
Lymphoma Survivors

Introduction: Although erectile dysfunction (ED) is one of known long-term complications among male lymphoma survivors, it is not commonly reported, particularly in Southeast Asia. This study aimed to determine the prevalence of ED in lymphoma survivors in Malaysia and its association with anxiety and depression, and effects on quality of life. Methods: This was a cross-sectional study conducted at a tertiary hospital in Malaysia. Patients were all male lymphoma survivors. The self-administered International Index of Erectile Function questionnaire was used to screen for ED. The Hospital Anxiety and Depression Score questionnaire was used to assess for anxiety and depression, and quality of life was assessed using the European Organization for Research and Treatment of Cancer quality of life questionnaire. Results: Overall, 106 patients were recruited. Mean age was 55.7 years, with 61.3% of patients aged above 50 years. Only 67.0% of patients were sexually active and 81.7% of these reported the presence of ED, with only 4.2% having severe ED. Prevalence of ED among younger patients (age ≤ 50 years old) was 64.5%.The most common reason given by patients who were not sexually active was fatigue. Age was the only factor found to be associated with ED (p < 0.005) and severity of ED increased with age. There was no association between ED and psychological stress or quality of life. Conclusion: Prevalence of ED and absence of sexual activity in lymphoma survivors was high. This should serve as a reminder to the treating clinician to offer early treatment and counselling.

scholarly journals Evaluation of Malnutrition and Quality of Life in Patients Treated for Oral and Oropharyngeal Cancer

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Shruthi Pingili ◽  
Junaid Ahmed ◽  
Nanditha Sujir ◽  
Nandita Shenoy ◽  
Ravikiran Ongole
Keyword(s):  
Quality Of Life ◽  
Oropharyngeal Cancer ◽  
Cross Sectional Study ◽  
High Morbidity ◽  
Life Questionnaire ◽  
Chi Square ◽  
Cross Sectional ◽  
European Organization ◽  
Oral And Oropharyngeal Cancer

Background. Oral and oropharyngeal cancer is a debilitating disease with high morbidity and mortality. Depending on the site and extent of the involvement of the cancer and the type of treatment modality, these patients can develop pain, trismus, xerostomia, dysphagia, and taste disturbances, compromising them socially and nutritionally. The aim of the study was to evaluate malnutrition and quality of life in patients treated for oral and oropharyngeal cancer. Methodology. A cross-sectional study was conducted which included 97 patients treated for oral and oropharyngeal cancer. The quality of life of the selected patients was assessed by using a validated European Organization for the Research and Treatment of Cancer’s Quality of Life Questionnaire, Head and Neck and Mandibular Function Impairment Questionnaire. Pre- and posttreatment weight of the patients were assessed, and weight loss of ≥10% of pretreatment weight was considered as malnutrition. The chi-square test was used to correlate the symptoms with the quality of life. A paired t test was used to assess the differences in weight before and after treatment, and a p value of <0.005 was considered as significant. Results. The most commonly reported symptoms were xerostomia (93.81%), pain (81.44%), and dysphagia (76.3%). A total of 40.2% of the individuals in the study had malnutrition. Malnutrition was comparatively lower in the group who had nutritional supplements. Conclusion. The quality of life in patients treated for oral and oropharyngeal cancer deteriorates immediately after the treatment; however, it significantly improves over time.

scholarly journals The Association between ADL Ability and Quality of Life among People with Advanced Cancer

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Mette Falk Brekke ◽  
Karen la Cour ◽  
Åse Brandt ◽  
Hanne Peoples ◽  
Eva Ejlersen Wæhrens
Keyword(s):  
Quality Of Life ◽  
Advanced Cancer ◽  
Cross Sectional Study ◽  
Life Questionnaire ◽  
Occupational Science ◽  
Cross Sectional ◽  
European Organization ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

Background. Occupational therapy and occupational science are founded on the theoretical core assumption that occupation and quality of life (QoL) are closely related. However, such theoretical core assumptions must be supported through empirically based research. Objective. To investigate the association between QoL and occupation, here self-reported and observed ADL abilities as a part of occupation, among people with advanced cancer, including determining whether self-reported or observed ADL ability had the stronger association with QoL. Methods. The study was nested in a cross-sectional study. The association between ADL ability and QoL among 108 people with advanced cancer was investigated using the ADL Interview (ADL-I), the Assessment of Motor and Process Skills (AMPS), and the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC-QLQ-C30). Results and Conclusions. Results showed that high observed ADL motor ability was associated with high QoL. In contrast, observed ADL process ability and self-reported ADL ability were not significantly associated with QoL. Oppositely expected, observed ADL ability had a stronger association with QoL than self-reported ADL ability. Thereby, the study to some extent contributes knowledge confirming the theoretical core assumptions about the relation between occupation, here performance of ADL, and QoL.

scholarly journals Evaluation of the functional capacity and quality of life of children and adolescents during and after cancer treatment

2022 ◽  
Vol 40 ◽  
Author(s):  
Bruna Kuhn ◽  
Luciane Dalcanale Moussalle ◽  
Janice Luisa Lukrafka ◽  
Giana Berleze Penna ◽  
Abelardo de Oliveira Soares Júnior
Keyword(s):  
Quality Of Life ◽  
Cancer Treatment ◽  
Children And Adolescents ◽  
Functional Capacity ◽  
Post Treatment ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Percentage Difference ◽  
Hematological Cancers

ABSTRACT Objective: To evaluate the functional capacity and quality of life of children and adolescents during cancer treatment and post-treatment. Methods: Cross-sectional study of patients during cancer treatment and post-treatment, assessed by the 6-minute walk test (6MWT) and the Pediatric Quality of Life ™ questionnaire (cancer module). Results: Sixty-five patients, aged 11.2±3.5 years, mostly males (50.8%) and white (90.8%), with high incidence of hematological cancers (81.5%) participated in the study. The performance in the 6MWT was 23.1% inferior comparing the mean predicted and achieved (584.3±5 and 447.7±78.6 m, respectively). The percentage difference between the predicted and achieved 6MWT, and the different phases of cancer treatment were significantly different between patients in treatment (73.7±12.8) and post-treatment (84.5±9.1). When grouped by the different diagnoses, it was possible to observe that the distance covered by the patients with leukemia showed results closer to that predicted (80.7±11.7). Regarding the health-related quality of life questionnaire (HRQL), the child’s perception (78.0±14.56) was better than that reported by their parents (72.4±17.74). However, when we compared HRQL with the 6MWT, there was no association between them (p=0.597). Conclusions: Children and adolescents undergoing cancer treatment or post-treatment showed a 23% deficit in functional capacity. In relation to HRQL results, children’s perception was higher than that of their parents.

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