scholarly journals Clinical correlates of the restless legs syndrome

2012 ◽  
Vol 70 (7) ◽  
pp. 529-531 ◽  
Author(s):  
Luis Fabiano Marin ◽  
Andre Carvalho Felicio ◽  
William Adolfo Santos ◽  
Lucila Bizari Prado ◽  
Gilmar Fernandes Prado
Keyword(s):  
Restless Legs Syndrome ◽  
Treatment Options ◽  
Disease Onset ◽  
Epidemiological Studies ◽  
Deficiency Anemia ◽  
Clinical Correlates ◽  
Restless Legs ◽  
Male Sex ◽  
Stage Renal Disease ◽  
End Stage

OBJECTIVE: To determine the clinical correlates of the restless legs syndrome (RLS) in a Brazilian sleep disorders center. METHODS: We retrospectively studied 118 patients with RLS from January, 2004, to December, 2010. The analyzed variables were: age at disease onset, gender, race, years of school instruction, primary and secondary RLS, and treatment options. RESULTS: Among the studied patients, 83.9% were women with a female/male sex ratio of 5:1. Mean age of the patients at symptom onset ± standard deviation was 41.7±17.9 years-old. The primary RLS was found in 85% of patients. The other 15% remainders consisted of secondary forms, and they were associated with neuropathy, iron deficiency anemia, end-stage renal disease, or Parkinson's disease. Drug therapy for RLS was introduced in 67% of patients. CONCLUSIONS: Most patients presented primary RLS with an early disease onset. Further epidemiological studies are welcomed to provide better information on secondary RLS in Brazil.

scholarly journals Epidemiology, impact, and treatment options of restless legs syndrome in end-stage renal disease patients: an evidence-based review

2014 ◽  
Vol 85 (6) ◽  
pp. 1275-1282 ◽  
Author(s):  
Christoforos D. Giannaki ◽  
Georgios M. Hadjigeorgiou ◽  
Christina Karatzaferi ◽  
Marios C. Pantzaris ◽  
Ioannis Stefanidis ◽  
...  
Keyword(s):  
Renal Disease ◽  
Restless Legs Syndrome ◽  
End Stage Renal Disease ◽  
Treatment Options ◽  
Evidence Based ◽  
Restless Legs ◽  
Stage Renal Disease ◽  
End Stage

Clinical management of restless legs syndrome in end-stage renal disease patients

CNS Spectrums ◽  
2016 ◽  
Vol 22 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Zeyad T. Sahli ◽  
Jae Jo ◽  
Shaker A. Mousa ◽  
Frank I. Tarazi
Keyword(s):  
Renal Disease ◽  
Restless Legs Syndrome ◽  
End Stage Renal Disease ◽  
Treatment Guidelines ◽  
Small Sample ◽  
Limited Information ◽  
Restless Legs ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Restless legs syndrome (RLS) is a common neurological movement disorder, characterized by restless and unpleasant sensations in the deep inside of legs. The symptoms of RLS are less noticeable during daytime, but more prevalent at night. Therefore, the disorder can induce low quality of life, insomnia, and impairment of daytime activity. RLS in end-stage renal disease (ESRD) patients is especially problematic due to premature discontinuation of dialysis and increased mortality. The prevalence of RLS among dialysis patients is much higher compared to the prevalence of the same disorder in patients with normal renal functions. Even though there are recommended treatment guidelines for the general population established by Medical Advisory Board of the RLS foundation, which include the use of dopamine agonists, levodopa, gabapentin, benzodiazepines, and opioids, limited information is available on the effects of these therapies in ESRD patients. Since the existing clinical data were extrapolated from small sample sizes in short-term clinical trials, further clinical studies are still needed to better assess the efficacy, safety, and tolerability of these medications in patients with ESRD.

Restless legs syndrome is associated with cardio/cerebrovascular events and mortality in end-stage renal disease

2014 ◽  
Vol 22 (1) ◽  
pp. 142-149 ◽  
Author(s):  
C.-H. Lin ◽  
H.-N. Sy ◽  
H.-W. Chang ◽  
H.-H. Liou ◽  
C.-Y. Lin ◽  
...  
Keyword(s):  
Renal Disease ◽  
Restless Legs Syndrome ◽  
End Stage Renal Disease ◽  
Restless Legs ◽  
Cerebrovascular Events ◽  
Stage Renal Disease ◽  
End Stage

Restless legs syndrome in end-stage renal disease: Clinical characteristics and associated comorbidities

2010 ◽  
Vol 11 (8) ◽  
pp. 785-790 ◽  
Author(s):  
Sonia Maria Holanda Almeida Araujo ◽  
Veralice Meireles Sales de Bruin ◽  
Lucas A. Nepomuceno ◽  
Marcos Lelio Maximo ◽  
Elizabeth de Francesco Daher ◽  
...  
Keyword(s):  
Renal Disease ◽  
Restless Legs Syndrome ◽  
End Stage Renal Disease ◽  
Clinical Characteristics ◽  
Restless Legs ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Itch and Ache on Dialysis: New Approaches to Manage Uremic Pruritus and Restless Legs

2019 ◽  
Vol 49 (1-2) ◽  
pp. 222-227 ◽  
Author(s):  
Soraya Arzhan ◽  
Maria-Eleni Roumelioti ◽  
Mark L. Unruh
Keyword(s):  
Treatment Options ◽  
Healthcare Providers ◽  
Restless Legs ◽  
Uremic Pruritus ◽  
Health Related Qol ◽  
Health Related ◽  
Maintenance Dialysis ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: Uremic pruritus (UP) and restless legs syndrome (RLS) are highly prevalent complaints among patients with end-stage renal disease (ESRD) undergoing chronic dialysis. These chronic troublesome symptoms lead to a significant decrease in quality of life (QOL) and increase in mortality rate. Despite their distressing characteristics, these symptoms usually remain under-recognized by healthcare providers. Therefore, careful history intake, and stepwise treatment are essential. Numerous pharmacological and non-pharmacological treatments have been demonstrated to help in controlling these 2 conditions. Summary: In this review, we discuss the latest findings regarding UP and RLS among ESRD patients on maintenance dialysis. We also examine different treatment options in this group of patients. The majority of these patients do not have the opportunity to receive a kidney transplant and need other treatments for these burdensome symptoms in order to improve their QOL and prognosis. Key Messages: UP and RLS are common but underdiagnosed conditions in ESRD patients on maintenance dialysis that are related to a decline in patients’ QOL and poor prognosis. The pathophysiology of these conditions remains not well understood. Therefore, controversies still exist on treatment options. Treating these conditions provides an opportunity to improve the health-related QOL and outcomes of dialysis patients.

Sign in / Sign up

Export Citation Format

Share Document