Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil

A study was carried out in the area of influence of the Porto Primavera Hydroelectric Power Station, in western São Paulo State, to investigate ecological and epidemiological aspects of malaria in the area and monitor the profile of the anopheline populations following the environmental changes brought about by the construction of the lake. Mosquitoes captured were analyzed by standardized indicator species analysis (ISA) before and during different flooding phases (253 m and 257 m elevations). The local human population was studied by means of parasitological (thin/thick blood smears), molecular (PCR) and serological tests. Serological tests consisted of Enzyme Linked Immunosorbent Assay (ELISA) with synthetic peptides of the circumsporozoite protein (CSP) from classic Plasmodium vivax, P. vivax variants (VK247 and "vivax-like"), P. malariae and P. falciparum and Indirect Immunofluorescence Assay (IFA) with asexual forms of P. vivax, P. malariae and P. falciparum. The results of the entomological survey indicated that, although the Anopheles darlingi population increased after the flooding, the population density remained very low. No malaria, parasite infection or DNA was detected in the inhabitants of the study area. However, there was a low frequency of antibodies against asexual forms and a significant prevalence of antibodies against P. vivax, P. vivax variants, P. falciparum and P. malariae; the presence of these antibodies may result from recent or less recent contact with human or simian Plasmodium (a parallel study in the same area revealed the existence of a sylvatic cycle). Nevertheless, these results suggest that, as in other places where malaria is present and potential vectors circulate, the local epidemiological conditions observed could potentially support the transmission of malaria in Porto Primavera Lake if infected individuals are introduced in sufficient numbers. Further studies are required to elucidate the phenomena described in this paper.

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Human disease in ribeira valley, brazil caused by caraparu, a group c arbovirus - Report of a case

Revista do Instituto de Medicina Tropical de São Paulo ◽

10.1590/s0036-46651987000200009 ◽

1987 ◽

Vol 29 (2) ◽

pp. 112-116 ◽

Cited By ~ 7

Author(s):

Lygia Busch Iversson ◽

Amélia P. A. Travassos da Rosa ◽

Terezinha Lisieux M. Coimbra ◽

Ivani Bisordi Ferreira ◽

Elza da Silva Nassar

Keyword(s):

Human Disease ◽

Laboratory Data ◽

Sao Paulo ◽

Southeastern Brazil ◽

Antigenic Relationship ◽

São Paulo ◽

Antigenic Difference ◽

Serological Tests ◽

Paulo State ◽

São Paulo State

The clinical and laboratory data of a disease in a resident of Ribeira Valley, São Paulo State, southeastern Brazil, caused by an agent close or identical to Caraparu, a Group C arbovirus, was described. Although there is evidence of an intensive circulation of several arboviruses in the area, no diagnosis of human disease by these agents has been made, except the encephalitis cases caused by Rocio virus during an epidemic in 1975-1977. An antigenic difference between Caraparu strains isolated in São Paulo and in Pará States and a close antigenic relationship between Caraparu strain from São Paulo and Bruconha virus were suggested by the serological tests.

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The Importance of Coordinated Actions in Preventing the Spread of Yellow Fever to Human Populations: The Experience from the 2016-2017 Yellow Fever Outbreak in the Northeastern Region of São Paulo State

Canadian Journal of Infectious Diseases and Medical Microbiology ◽

10.1155/2019/9464768 ◽

2019 ◽

Vol 2019 ◽

pp. 1-11

Author(s):

Márcio Junio Lima Siconelli ◽

Danillo Lucas Alves Espósito ◽

Nathália Cristina Moraes ◽

Julia Maria Ribeiro ◽

Lívia Perles ◽

...

Keyword(s):

Public Health ◽

Yellow Fever ◽

Sao Paulo ◽

Human Populations ◽

Hemorrhagic Disease ◽

São Paulo ◽

Sylvatic Cycle ◽

Northeastern Region ◽

Paulo State ◽

São Paulo State

Yellow fever (YF) is a zoonotic arthropod-borne disease that is caused by the yellow fever virus (YFV) and characterized by a sylvatic and urban cycle. Its most severe presentation is manifested as a hemorrhagic disease, and it has been responsible for thousands of deaths in the last decades. This study describes the public health approaches taken to control the 2016-2017 YF outbreak in nonhuman primates (NHPs) that took place in the northeastern region of São Paulo state, Brazil. NHPs recovered from the field were necropsied, and YF diagnoses were made at the Laboratory of Molecular Virology, Ribeirão Preto Medical School and the Center of Pathology, Adolfo Lutz Institute of São Paulo. NHP samples were inoculated into Vero cells for YFV isolation. RNA extraction was performed directly from NHP tissues and tested by RT-qPCR. YFV-positive samples were confirmed by sequencing. Based on the rapid RT-qPCR results, surveillance actions were implemented in the entire region. Confirmatory histopathology and immunohistochemistry for YFV were also performed. Among nine NHPs, gross hepatic involvement was observed in six animals, five of which were YFV-RT-qPCR-positive. One YFV was isolated from the serum of an infant NHP. YFV RNA sequences diverged from the virus responsible for the last epizootic that occurred in São Paulo state, but it was similar to the current Brazilian epizootic. Public health actions included dissemination of information on YF transmission, investigation of the probable location of NHP infection, characterization of the environment, and subsequent creation of the blueprint from which prevention and control measures were implemented. The YFV sylvatic cycle occurred in the periurban areas of the northeastern region of São Paulo state, but no human cases were reported during this period, showing that integrated actions between human, animal, and environmental health professionals were critical to restrain the virus to the sylvatic cycle.

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Landscape formation, environmental changes and prehistoric occupation (Jacaré-Guaçu River Lowlands, Araraquara area, Southeast Brazil, Late Pleistocene-Holocene interval): correlation between geomorphological, pedological, geochronological and archaeological data

Quaternary and Environmental Geosciences ◽

10.5380/abequa.v10i1.57594 ◽

2019 ◽

Vol 10 (1) ◽

Author(s):

Pedro Michelutti Cheliz ◽

Regina Celia Oliveira

Keyword(s):

Late Pleistocene ◽

Environmental Changes ◽

Sao Paulo ◽

São Paulo ◽

Lateral Migration ◽

Paulo State ◽

Southeast Brazil ◽

Base Level ◽

São Paulo State ◽

Rocky Outcrops

This paper presents a geomorphological, pedological and geochronological characterization and contextualization of geomorphogenetic, chronomorphological and environmental sequences from the Araraquara area (central São Paulo State, Southeast Brazil), and their relationship to lithic material from hunter-gatherer archaeological lithic sites. A special emphasis is given to a detailed study of the lowlands of the Jacaré-Guaçu River (between the cities of Araraquara and Boa Esperança do Sul, São Paulo state, Brazil), near the Boa Esperança II hunter-gatherer archaeological site, BES II, in an area of clear asymmetry of the alluvial plain and adjacent slopes. Data derived from the survey of estimated morphogenetic and environmental dynamics are used to contextualize the archaeological material of the BES II site, which is discussed as being associated with the Pleistocene-Holocene transition (an unusual occupation age for the Brazil southeast). We pointed to alternation between successions linked to a quaternary manifestation of a longer pattern of changes of lateral flatting processes and stability of base level with others linked to vertical incision and adequacy to a new base level. We propose a geomorphological model for the Lowlands of Jacaré-Guaçu River, highlighting the possibility that the asymmetry of the plain would be linked to a wider heterogeneity of its geomorphological context of semidetails, partially correlated with the overlapping of neotectonic influence and environmental fluctuations. It is suggested that data from the physical environment of the above mentioned lowlands are compatible with absolute ages obtained by OSL (lower terrace Ia, 14,500±3000 years BP, basal gravel level of the surface coverings, to 10,900±1500 and 4090±340 years BP at the sandy soils and sediments above the gravel) and 14C (8630 years BP, at the level of gleyed sandy-clay soil of 120 cm deep of the low terraces IIa) on archaeological levels of the low terraces of the Jacaré-Guaçu river, in a context of climatic transition from semi-arid conditions to higher humidity, hydrological changes (ephemeral and torrential channels changing to oscillating regimes of perennial channels, with sets of meanders of variable widths of paleochannels, suggesting climatic changes related to the modifications of the fluvial patterns), successive fluctuations (< 10 m) of base levels and large (500 m) lateral migration of the main river to the north guiding the local chronomorphological successions between Late Pleistocene and Late Holocene. The landscape and fluvial dynamics changes over time has influenced the availability of attributes needed for the hunter-gatherer lifestyle (such as fluctuations in the deposition/exposure of river pebbles used as raw material for tool making). Those oscillations are presented as a contribution to explain alternation between more and less dense archaeological levels along the vertical cuts of the low terraces and the location of exception of the BES II site (installed on a fluvial plain and low terraces in a segment characterized by the rarity of rocky outcrops, while most sites in the Araraquara area are linked to slopes, proximal to rocky outcrops - primary sources of lithics artifacts making) on the geomorphological Araraquara area context

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On the perceptions and conceptions of tourists with regard to global environmental changes and their consequences for coastal and marine environments: A case study of the northern São Paulo State coast, Brazil

Marine Policy ◽

10.1016/j.marpol.2015.03.005 ◽

2015 ◽

Vol 57 ◽

pp. 85-92 ◽

Cited By ~ 6

Author(s):

Natalia Pirani Ghilardi-Lopes ◽

Alexander Turra ◽

Marcos S. Buckeridge ◽

Amanda Cristina Silva ◽

Flávio Augusto de Souza Berchez ◽

...

Keyword(s):

Environmental Changes ◽

Sao Paulo ◽

São Paulo ◽

Marine Environments ◽

Paulo State ◽

Global Environmental ◽

São Paulo State ◽

Global Environmental Changes

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Megaprojects - Socioeconomic and Environmental Dynamics in D. Pedro I-Tamoios Road Axis, São Paulo, Brazil

Advances in Research ◽

10.9734/air/2019/v18i630107 ◽

2019 ◽

pp. 1-15

Author(s):

Sônia Regina da Cal Seixas ◽

João Luiz de Moraes Hoefel

Keyword(s):

Environmental Changes ◽

Tourism Development ◽

Temporal Variations ◽

Sao Paulo ◽

Urban Structure ◽

São Paulo ◽

Natural Systems ◽

Paulo State ◽

Pedro I ◽

São Paulo State

Aims: Megaprojects development has generated changes in the socioeconomic and environmental structure of several regions. This paper aims to analyse socioenvironmental changes in 10 municipalities located along the D. Pedro I - Tamoios road axis, São Paulo state, Brazil, chosen for their regional relevance, and transformations caused by the roads duplication. Study Design: Analysis on how megaprojects influence the urban structure, the environment and different social groups, focusing in Gross Domestic Product (GDP), in different productive sectors (agricultural, services and industrial), in population growth and rural and urban scenarios. Place and Duration of Study: The study was realized in São Paulo State, Brazil, during 36 months, starting in July 2015 until July 2018, and the data used and analyzed to diverse indicators were from 1950 to 2014. Methodology: Sociodemographic data, the expansion of industry, services, tourism development and agricultural production of these municipalities were collected in government databases and through field surveys. They were analysed through integrated methodologies with qualitative and quantitative approaches, based on temporal variations for the studied municipalities and for the average of São Paulo State, Brazil, with focus on social and environmental changes that took place in this study area. Results: The results indicate that an intense process of industrialisation, tourism development, urban growth and population dynamics has accompanied the recent decade’s expansion of major roads in São Paulo State, Brazil, and that these processes contribute to changes that affect natural systems and may accelerate climate changes. Conclusion: It verified that this megaproject development had not considered the sustainability of regional natural resources, in a manner that promotes environmental and living quality to the population.

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Visceral larva migrans: a seroepidemiological survey in five municipalities of São Paulo State, Brazil

Revista do Instituto de Medicina Tropical de São Paulo ◽

10.1590/s0036-46651990000300010 ◽

1990 ◽

Vol 32 (3) ◽

pp. 204-210 ◽

Cited By ~ 44

Author(s):

Pedro Paulo Chieffi ◽

Mirthes Ueda ◽

Eide Dias Camargo ◽

Ana Maria Carvalho de Souza ◽

Marilda L. da Silva Guedes ◽

...

Keyword(s):

Toxocara Canis ◽

Sao Paulo ◽

Larva Migrans ◽

Enzyme Linked Immunosorbent Assay ◽

São Paulo ◽

Paulo State ◽

São Paulo State ◽

The Difference ◽

Male Subjects ◽

Positive Results

An enzyme-linked immunosorbent assay (ELISA), employing antigens from Toxocara canis larvae and the absortion of suspected sera with Ascaris lumbricoides extracts was used in a seroepidemiological study performed in five municipalities of São Paulo State, Brazil (São Paulo, Campinas, Santos, Marília and Presidente Prudente) in order to determine the frequency of antibodies to Toxocara. In 2,025 blood samples collected, 806 proceeded from male subjects and 1,219 from females; 483 samples were collected from subjects under 15 years of age and the remaining 1,542 from subjects aged 15 years or over. Among the 2,025 sera investigated, 3.60% had antibodies to Toxocara at significant levels. A moderate predominance of infection with Toxocara among male subjects (3.72%) was observed, although the difference was not statistically significant when this rate was compared with that for female (3.28%). Related to age, a higher frequency of positive results was detected among subjects under 15 years (6.41%) against the older group (2.53%). A trend of more elevated rates of infection was observed in municipalities with high demographic densities (São Paulo, Campinas and Santos). Nevertheless, such findings only appeared to be statistically significant in subjects younger than 15 years.

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First Report of Natural Occurrence of Zucchini Lethal Chlorosis Tospovirus on Cucumber and Chrysanthemum Stem Necrosis Tospovirus on Tomato in Brazil

Plant Disease ◽

10.1094/pdis.1998.82.12.1403a ◽

1998 ◽

Vol 82 (12) ◽

pp. 1403-1403 ◽

Cited By ~ 23

Author(s):

Tatsuya Nagata ◽

Renato de O. Resende ◽

Elliot W. Kitajima ◽

Helcio Costa ◽

Alice K. Inoue-Nagata ◽

...

Keyword(s):

Electron Microscopy ◽

Sao Paulo ◽

Spherical Particles ◽

Enzyme Linked Immunosorbent Assay ◽

Natural Occurrence ◽

São Paulo ◽

First Report ◽

Paulo State ◽

Stem Necrosis ◽

São Paulo State

During a field survey in 1994, five cucumber (Cucumis sativus) cv. Hokushin plants showing symptom of yellowing, mottling, and vein banding on the leaves were collected from a commercial field of the Federal District. By electron microscopy, quasi-spherical particles with double membrane, typical tospovirus-like particles were found in the infected leaf material. All samples strongly reacted with antibody of zucchini lethal chlorosis tospovirus (ZLCV), but not with antibodies of other to-spoviruses reported in Brazil (1): tomato spotted wilt virus (TSWV), tomato chlorotic spot virus (TCSV), groundnut ringspot virus (GRSV), chrysanthemum stem necrosis virus (CSNV), or iris yellow spot virusonion isolate (IYSV-BR). The virus was identified as ZLCV, which was first isolated in 1994 from zucchini (Cucurbita pepo) in São Paulo State, Brazil. Tomato (Lycopersicon esculentum) plants showing stem necrosis and necrotic spots and rings on the leaves were collected in Viçosa, Minas Gerais State. By electron microscopy, molecular studies, and enzyme-linked immunosorbent assay with antibodies of the six tospoviruses occurring in Brazil, the virus was identified as CSNV. This virus was first reported in 1995 on a Chrysanthemum sp. in São Paulo State and recently reported in the Netherlands from Dendranthema indicum. This is the first report of the natural occurrence of ZLCV and CSNV on cucumber and tomato, respectively. Reference: (1) A. C. de Ávila et al. 1998. Pages 32–34 in: Int. Symp. on Tospoviruses and Thrips in Floral and Vegetable Crops, 4th.

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