The effect of sun exposure on 25-hydroxyvitamin D concentrations in young healthy subjects living in the city of São Paulo, Brazil

Abstract Micronutrient deficiency is common in patients with HIV/AIDS, usually caused by mal-absorption and/or drug interactions. 25-hydroxyvitamin D is of fundamental importance for the homeostasis of musculoskeletal health. The current study aimed to evaluate the nutritional status of HIV-infected subjects in order to make their nutritional diagnoses, including their vitamin D blood levels and to estimate their consumption of vitamin D. The study included 98 HIV-1-infected subjects, followed at University of São Paulo Medical School - HC-FMUSP. We performed a nutritional evaluation, along with the determination of patients’ serum 25-hydroxyvitamin D and calcium concentration, biochemical analyses and an anthropometric assessment. In the medical interview a 24-hour food recall was used (R24) to estimate daily calorie intake, macronutrients, calcium and vitamin D. A high level of vitamin D deficiency was observed in our patients: 83.4% of them had levels below 30 ng/ml; they also presented an increased risk of cardiovascular disease, along with a high consumption of dietary fat. Factors related to the virus itself and to the use of antiretroviral drugs may have contributed for the low vitamin D levels seen in our HIV-1-infected patients.

Download Full-text

Seasonal variation in the serum 25-hydroxyvitamin D levels of young and elderly active and inactive adults in São Paulo, Brazil

Dermato-Endocrinology ◽

10.4161/derm.24476 ◽

2013 ◽

Vol 5 (1) ◽

pp. 211-217 ◽

Cited By ~ 29

Author(s):

Sergio Setsuo Maeda ◽

Gabriela Luporini Saraiva ◽

Lilian Fukusima Hayashi ◽

Maysa Seabra Cendoroglo ◽

Luiz Roberto Ramos ◽

...

Keyword(s):

Seasonal Variation ◽

Sao Paulo ◽

São Paulo ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D

Download Full-text

Increases in summer serum 25-hydroxyvitamin D (25OHD) concentrations in elderly subjects in São Paulo, Brazil vary with age, gender and ethnicity

BMC Endocrine Disorders ◽

10.1186/1472-6823-10-12 ◽

2010 ◽

Vol 10 (1) ◽

Cited By ~ 16

Author(s):

Sergio S Maeda ◽

Ilda S Kunii ◽

Lilian F Hayashi ◽

Marise Lazaretti-Castro

Keyword(s):

Sao Paulo ◽

Elderly Subjects ◽

São Paulo ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D

Download Full-text

25-Hydroxyvitamin D Delayed Response to Seasonal Ultraviolet Radiation Type B Variation: The São Paulo Vitamin D Evaluation Study (SPADES)

10.1210/endo-meetings.2011.part2.p26.p2-126 ◽

2011 ◽

pp. P2-126-P2-126

Author(s):

Sergio Setsuo Maeda ◽

Gabriela Luporini Saraiva ◽

Lilian F Hayashi ◽

Maysa Seabra Cenderoglo ◽

Luiz Roberto Ramos ◽

...

Keyword(s):

Vitamin D ◽

Ultraviolet Radiation ◽

Evaluation Study ◽

Sao Paulo ◽

Delayed Response ◽

São Paulo ◽

Type B ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D ◽

Radiation Type

Download Full-text

Erratum: High frequency of deficient consumption and low blood levels of 25-hydroxyvitamin D in HIV-1-infected adults from São Paulo city, Brazil

Scientific Reports ◽

10.1038/srep14587 ◽

2015 ◽

Vol 5 (1) ◽

Author(s):

Stephanie Hael Sales ◽

Sandra Maria Matta ◽

Daniela Cardeal da Silva ◽

Tatiane Assone ◽

Luiz Augusto M. Fonseca ◽

...

Keyword(s):

High Frequency ◽

Sao Paulo ◽

Blood Levels ◽

São Paulo ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D ◽

Hiv 1

Download Full-text

Seasonal Variation of Suicide in the City of São Paulo, Brazil, 1996–2010

Crisis ◽

10.1027/0227-5910/a000222 ◽

2014 ◽

Vol 35 (1) ◽

pp. 5-9 ◽

Cited By ~ 10

Author(s):

Daniel Hideki Bando ◽

Fernando Madalena Volpe

Keyword(s):

Seasonal Pattern ◽

Total Sample ◽

Sao Paulo ◽

Seasonal Patterns ◽

São Paulo ◽

Health Statistics ◽

Males And Females ◽

June July ◽

The City ◽

Over Time

Background: In light of the few reports from intertropical latitudes and their conflicting results, we aimed to replicate and update the investigation of seasonal patterns of suicide occurrences in the city of São Paulo, Brazil. Methods: Data relating to male and female suicides were extracted from the Mortality Information Enhancement Program (PRO-AIM), the official health statistics of the municipality of São Paulo. Seasonality was assessed by studying distribution of suicides over time using cosinor analyses. Results: There were 6,916 registered suicides (76.7% men), with an average of 39.0 ± 7.0 observed suicides per month. For the total sample and for both sexes, cosinor analysis estimated a significant seasonal pattern. For the total sample and for males suicide peaked in November (late spring) with a trough in May–June (late autumn). For females, the estimated peak occurred in January, and the trough in June–July. Conclusions: A seasonal pattern of suicides was found for both males and females, peaking in spring/summer and dipping in fall/winter. The scarcity of reports from intertropical latitudes warrants promoting more studies in this area.

Download Full-text

Reaching Out to the Needy? Access to Justice and Public Attorneys’ Role in Right to Health Litigation in the City of Sao Paulo

SSRN Electronic Journal ◽

10.2139/ssrn.2165209 ◽

2012 ◽

Cited By ~ 1

Author(s):

Daniel Wang ◽

Octavio Luiz Motta Ferraz

Keyword(s):

Right To Health ◽

Sao Paulo ◽

Access To Justice ◽

São Paulo ◽

The City ◽

The Needy

Download Full-text

Comparison of Vitamin D and 25-Hydroxyvitamin D Concentrations in Human Breast Milk between 1989 and 2016–2017

Nutrients ◽

10.3390/nu13020573 ◽

2021 ◽

Vol 13 (2) ◽

pp. 573

Author(s):

Naoko Tsugawa ◽

Mayu Nishino ◽

Akiko Kuwabara ◽

Honami Ogasawara ◽

Maya Kamao ◽

...

Keyword(s):

Vitamin D ◽

Breast Milk ◽

Sun Exposure ◽

Stepwise Multiple Regression ◽

Human Breast Milk ◽

Vitamin D Status ◽

Human Breast ◽

Hydroxyvitamin D ◽

Lactating Mothers ◽

25 Hydroxyvitamin D

Background: Breast milk is considered the optimal source of nutrition during infancy. Although the vitamin D concentration in human breast milk is generally considered poor for infants, vitamin D in breast milk is an important source for exclusively breastfed infants. Increases in vitamin D insufficiency and deficiency in lactating mothers may reduce vitamin D concentrations in breast milk. This study aimed to compare vitamin D and 25-hydroxyvitamin D (25OHD) concentrations in breast milk collected in 1989 and 2016–2017 and simultaneously analyze them with liquid chromatography-tandem mass spectrometry (LC-MS/MS); the association between the lifestyle of recent lactating mothers (2016–2017) and vitamin D status in human breast milk was also evaluated. Method: Lactating mothers were recruited from three regions of Japan in 1989 (n = 72) and 2016–2017 (n = 90), and milk from 3–4 months was collected in summer and winter. The samples were strictly sealed and stored at −80℃ until measurement. Breast milk vitamin D and 25OHD concentrations were analyzed by LC-MS/MS. Vitamin D intake, sun exposure, and sunscreen use of the lactating mothers in 2016–2017 were assessed. Results: Both vitamin D and 25OHD concentrations in breast milk were higher in the summer regardless of the survey year. Significantly lower vitamin D and 25OHD concentrations were observed in 2016–2017 compared with 1989 in summer, but no survey year difference was observed in winter. The stepwise multiple regression analyses identified season, daily outdoor activity, and suntan in the last 12 months as independent factors associated with vitamin D3 concentrations. Conclusion: The results suggest that low vitamin D status in recent lactating mothers may have decreased vitamin D and 25OHD concentrations in breast milk compared with the 1980s. These results are helpful for developing public health strategies to improve vitamin D status in lactating mothers and infants.

Download Full-text