scholarly journals Investigating the relationship between hemodynamic and metabolic parameters in portal triade occlusion following hemorrhagic shock

2005 ◽  
Vol 20 (1) ◽  
pp. 22-27 ◽  
Author(s):  
Mauro José Fontelles ◽  
Mario Mantovani ◽  
Elcio Shiyoiti Hirano ◽  
Rosana Celestina Morandin

PURPOSE: To determine whether metabolic and hemodynamic parameters are "mathematically" coupled in rats submitted to portal triad occlusion following controlled hemorrhagic shock state. METHODS: Pearson's coefficient (r-value) analysis was performed. Differences considered significant at p<0.05 and -0.50>r>0.50. RESULTS: It was observed that there is a direct proportional relationship to HCO3- with pCO2 (r=0.66), base deficit (r=0.87) and inverse with serum lactate (r=-0.54). pCO2 was directly associated with MAP (r=0.51), and inversely with pH (r=-0.64). Hematocrit was directly associated with HR (r=0.72) and CI (r=0.76), and serum lactated was inversely associated with base deficit (r=-0.61). CONCLUSION: In rats submitted to Pringle's maneuver during 15 minutes following hemorrhagic shock state, there is a mathematical coupling with a very good correlation between several hemodynamic and metabolic variables.

2007 ◽  
Vol 28 (2) ◽  
pp. 231-240 ◽  
Author(s):  
Amalia Cochran ◽  
Linda S. Edelman ◽  
Jeffrey R. Saffle ◽  
Stephen E. Morris

2003 ◽  
Vol 18 (5) ◽  
pp. 392-397
Author(s):  
Mario Mantovani ◽  
Mauro José Fontelles ◽  
Elcio Shiyoiti Hirano ◽  
Rosana Celestina Morandin ◽  
André Almeida Schenka

PURPOSE: To study the effects of total hepatic ischemia, and reperfusion on the accumulation of neutrophils in the brain of rats submitted to normovolemic conditions as well as to controlled hemorrhagic shock state. METHODS: Thirty two adult male Wistar rats, were divided into four groups: the Control group, was submitted to the standard procedures for a period of 60 min of observation; Shock group, was submitted to controlled hemorrhagic shock (mean arterial blood pressure=40mmHg, 20min) followed by volemic resuscitation (lactated Ringer's solution + blood, 3:1) and reperfusion for 60min; Pringle group, was submitted to total hepatic ischemia for 15min and reperfusion for 60min. The total group was submitted to controlled hemorrhagic shock for 20min followed by volemic resuscitation (lactated Ringer's solution + blood, 3:1), total hepatic ischemia for 15min and reperfusion for 60min. Measurements of serum lactate and base excess were used to characterize the hemorrhagic shock state with low tissue perfusion. The counting of neutrophils on the brain was performed after the euthanasia of animals. RESULTS: The values for the counting of neutrophils on the brain indicate that did not occur difference among studied groups (p=0.196) (Control 0.12± 0.11, Shock 0.12± 0.13, Pringle 0.02± 0.04, Total 0.14± 0.16). CONCLUSION: Hemorrhagic shock associated to total hepatic ischemia for 15 minutes, followed by 60 minutes of reperfusion, did not causes significant neutrophils accumulation in the brain of rats.


Critical Care ◽  
2010 ◽  
Vol 14 (Suppl 1) ◽  
pp. P161
Author(s):  
K Jonishi ◽  
Y Sakamoto ◽  
Y Ueno ◽  
H Matsumoto ◽  
Y Hara ◽  
...  

Author(s):  
P.A. Popov ◽  
◽  
D.V. Gruznov ◽  
S.V. Tokarev ◽  
◽  
...  

The article presents the results of determining the relationship between the total microbial number and microbial ATP on the surface of milking equipment before and after treatment with neutral anolyte ANK-SUPER. The possibility of using the ATP-bioluminescence method to control the quality of sanitation of milking equipment on dairy farms is shown. Laboratory studies revealed a proportional relationship between the level of bacterial ATP and the number of bacteria on the surface of milking equipment before and after sanitation.


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Adel Mikhail Fahmy ◽  
Ahmed Kamal ◽  
Wael Abd Elmonem Mohamed Abdelwahab ◽  
Ameer Shokry Ahmed

Abstract Background Tissue perfusion and oxygenation monitoring is the fundamental of management to immediately identify and properly manage (impending) organ dysfunction in septic shock. This is a study of a prospective randomized trial that aims to comparing the prognostic value of lactate clearance versus base deficit correction as an indicator of tissue perfusion in septic shock, trying to prove the superiority of one over the other. Objective To assess the clinical utility of lactate clearance and arterial base deficit correction in predicting mortality in septic shock. Patients and Methods This is a Prospective randomized observational study that was conducted to assess the clinical utility of lactate clearance and arterial base deficit in predicting mortality in septic shock. This study included forty patients who were divided into two equal groups; each of twenty patients, group I (non-survivors), and group II (survivors). Results In this study, the base deficit values revealed statistically notable difference between the two groups at admission, 18 hours, 24 hours and 2 days of admission. The values revealed no notable difference at the 3rd. 4th, and 5th day of admission. At the 6th and 7th day of admission, the base deficit started to increase again in the non-survivor group with statistically notable increase in the values as compared to the survivor group. The cutoff point of base deficit to differentiate between nonsurvivors from survivors was &gt; 11.43 with 62% sensitivity and 100% specificity. In this study, initial serum lactate levels at admission revealed higher accuracy in prediction of mortality as compared with initial base deficit. Conclusion Lactate clearance is a better predictor of mortality and morbidity than base deficit correction.


2011 ◽  
Vol 80 (2) ◽  
pp. 84 ◽  
Author(s):  
Yong Suk Cho ◽  
Hyeong Tae Yang ◽  
Haejun Yim ◽  
Dohern Kim ◽  
Jun Hur ◽  
...  

2018 ◽  
Vol 18 (4) ◽  
pp. 395-412 ◽  
Author(s):  
Wanna Carvalho Fontes ◽  
Giovanni Gonçalves Fontes ◽  
Ellen Cristine Pinto Costa ◽  
Julia Castro Mendes ◽  
Guilherme Jorge Brigolini Silva ◽  
...  

Abstract The present work discloses the development of a sustainable cement tile (SCT) produced with Iron Ore Tailings from tailings dams (IOT). Initially, technical evaluation and environmental analysis of IOT were performed through physical, chemical and morphological characterisation, leaching and dissolution tests. Its feasibility as a pigment was also investigated. Subsequently, the value analysis was performed, starting from an empathy map to a study on environmental, social and emotional values in the relationship between people and product. As result, the IOT presented fine, crystalline particles, no toxicity, and is technically feasible to be employed as filler, aggregate and pigment in the production of SCT. The colour layer of the SCT presented more homogeneous colour and less pores than conventional ones. Therefore, the design of the SCT was developed, incorporating intangible values such as: environmental ideology, local identity and social expression. In this sense, the present work seeks to assist in the decision-making process involving IOT as construction material.


2018 ◽  
Vol 27 (1) ◽  
pp. 57-67 ◽  
Author(s):  
Fupeng Yin ◽  
Qi Gao ◽  
Xue Ji

The appropriate iteration process model is the basis for managing and optimizing the product development process. In this article, we attempt to introduce the concept of process effectiveness and process value. The relationship between rework probability and process effectiveness is discussed. The evolution function of process effectiveness is proposed to drive the overlapped iteration process of multi-coupled activities. The evolution process with input information update is studied, and a simulation model is presented to obtain the accurate iteration process of development. It is useful to analyze the risks during development, and has good flexibility and versatility. The calculation method of process value for overlapped iteration process is given, and an optimization model for product development process is provided. The model is used to improve the development process of the stamping die of a car roof. With the model, we can get a suitable overlapping rate of multi-coupled activities to improve development performance.


2019 ◽  
Vol 2 (2) ◽  
pp. 103-112
Author(s):  
Asfa Ashraf ◽  
Kamran Ishfaq ◽  
Muhammad Umair Ashraf ◽  
Zahid Zulfiqar

The present study aimed to investigate the relationship between parenting styles (authoritarian, authoritative and permissive) and Big-five personality traits (extraversion, agreeableness, neuroticism, conscientiousness and openness) among the students of Bahauddin Zakariya University Multan, Pakistan. For this purpose, a total number of 281 students from different faculties (Natural and social sciences) were selected through systematic sampling technique and the respondents responded to parenting authority questionnaire (PAQ) by Buri (1991) and Big-five inventory (BFI) john and Srivastava (1999). Data were analyzed by using SPSS-21 version, and Pearson correlation (r=0.01) was applied to find out the relationship, direction and consistency between predictor and criterion variable. Results indicated a directly proportional relationship between parenting styles (authoritarian, authoritative & permissive) and big five personality traits.


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