scholarly journals Definition and application of neuropsychological test battery to evaluate postoperative cognitive dysfunction

2015 ◽  
Vol 13 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Lívia Stocco Sanches Valentin ◽  
Ricardo Pietrobon ◽  
Wagner de Aguiar Junior ◽  
Ruth Pinto Camarão Rios ◽  
Mariane Galzerano Stahlberg ◽  
...  
Keyword(s):  
General Anesthesia ◽  
Cognitive Dysfunction ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Neuropsychological Test ◽  
Postoperative Cognitive Dysfunction ◽  
Test Battery ◽  
Cutoff Point ◽  
Neuropsychological Test Battery ◽  
State Examination

Objective To investigate the adequacy of the neuropsychological test battery proposed by the International Study of Postoperative Cognitive Dysfunction to evaluate this disorder in Brazilian elderly patients undergoing surgery under general anesthesia. Methods A neuropsychological assessment was made in patients undergoing non-cardiac surgery under general anesthesia, aged over 65 years, literate, with no history of psychiatric or neurological problems and score on the Mini Mental State Examination at or above the cutoff point for the Brazilian population (>18 or >23) according to the schooling level of the subject. Eighty patients were evaluated by a trained team of neuropsychologists up to 24 hours before elective surgery. Results Among the patients evaluated, one was excluded due to score below the cutoff point in the Mini Mental State Examination and two did not complete the test battery, thus remaining 77 patients in the study. The mean age was 69±7.5 years, and 62.34% of the subjects had ±4 years of study. The subjects had significantly lower averages than expected (p<0.001) for normative tables on neuropsychological tests. Conclusion The study demonstrated the applicability of the instruments in the Brazilian elderly and low schooling level population, but suggested the need to determine cutoff points appropriate for these individuals, ensuring the correct interpretation of results. This battery is relevant to postoperative follow-up evaluations, favoring the diagnosis of postoperative cognitive dysfunction in patients undergoing different types of surgery and anesthetic techniques.

scholarly journals Lifetime Musical Training and Cognitive Performance in a Memory Clinic Population: A Cross-Sectional Study

2020 ◽  
pp. 102986492091863
Author(s):  
Daisy Fancourt ◽  
Katharina Geschke ◽  
Andreas Fellgiebel ◽  
Alexandra Wuttke-Linnemann
Keyword(s):  
Mental State ◽  
Mini Mental State Examination ◽  
Musical Training ◽  
Cognitive Impairments ◽  
Neuropsychological Test ◽  
Word List ◽  
Memory Clinic ◽  
Cross Sectional ◽  
Examination Score ◽  
State Examination

Background: Music training has been found to be beneficial for young and healthy participants but the associations between musical training and the cognitive functioning of elderly participants have not been reported consistently. We examined whether lifetime musical training is associated with neuropsychological performance in a memory clinic population of older patients. Methods: A total of 478 patients (54.2% female, mean age 73.70 ± 6.22, mean Mini Mental State Examination score 25 ± 3) were included in the cross-sectional analyses. All patients were referred to the memory clinic due to cognitive impairments. During the course of diagnosis, all patients underwent neuropsychological tests using the CERAD neuropsychological assessment battery. Patients provided information on whether they ever learned to play an instrument for at least five years in their life. Results: Neuropsychological test results differed based on musical training ( p = .042). Overall, there were no differences in any domains of cognitive functioning, other than that patients with musical training performed worse on word list memory ( p = .008). However, this relationship varied based on the extent of cognitive impairments. Patients who were cognitively unimpaired (Mini Mental State Examination score 27–30) and had musical training showed better word list learning, whereas patients with cognitive impairments (Mini Mental State Examination score < 27) and musical training performed worse in word list learning ( p = .042) and word list recall ( p = .045). Discussion: Overall, there was little evidence of associations between specific neuropsychological test results and musical training. Only in cognitively unimpaired patients was there evidence that musical training had beneficial associations. In patients with cognitive impairment, there were suggestions of negative associations with verbal memory. Future research should longitudinally investigate the beneficial effects of musical training in people with and without cognitive impairments.

scholarly journals Effect of dexmedetomidine on postoperative cognitive dysfunction in elderly patients after general anaesthesia: A meta-analysis

2016 ◽  
Vol 44 (6) ◽  
pp. 1182-1190 ◽  
Author(s):  
Chengmao Zhou ◽  
Yu Zhu ◽  
Zhen Liu ◽  
Lin Ruan
Keyword(s):  
General Anaesthesia ◽  
Cognitive Dysfunction ◽  
Mini Mental State Examination ◽  
Mmse Score ◽  
Meta Analysis ◽  
Postoperative Cognitive Dysfunction ◽  
Cochrane Library ◽  
Methodologic Quality ◽  
The Cochrane Library ◽  
State Examination

Objective We undertook a meta-analysis to investigate the effect of dexmedetomidine on postoperative cognitive dysfunction (POCD). Methods We searched PubMed, EMBASE, the Cochrane Library, CNKI and Google Scholar to find randomized controlled trials (RCTs) of the influence of dexmedetomidine on POCD in elderly adults who had undergone general anaesthesia. Two researchers independently screened the literature, extracted data, and evaluated methodologic quality against inclusion and exclusion criteria. We used RevMan 5.2 to undertake our meta-analysis. Results Thirteen RCTs were included. Compared with controls, dexmedetomidine: 1) significantly reduced the incidence of POCD (relative risk = 0.59, 95% confidence interval [CI] 0.45–2.95) and improved Mini-Mental State Examination (MMSE) score (mean difference, MD = 1.74, 95% CI 0.43–3.05) on the first postoperative day; and 2) reduced the incidence of POCD after the first postoperative day (MD = 2.73, 95% CI 1.33–4.12). Conclusion Dexmedetomidine reduces the incidence of POCD and improves postoperative MMSE score.

Comparison of Mini-Mental State Examination and Clock Drawing Test with Orientation-Memory-Concentration Test in the Elderly with Cognitive Function Impairment in Jetis Sub-District, Yogyakarta

2020 ◽  
Author(s):  
Darren Eduardo William ◽  
◽  
Mitra Andini Sigilipoe ◽  
Widya Christine Manus ◽  
◽  
...  
Keyword(s):  
Cognitive Function ◽  
Cognitive Dysfunction ◽  
Mental State ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Clock Drawing Test ◽  
Clock Drawing ◽  
Drawing Test ◽  
Concentration Test ◽  
State Examination

ABSTRACT Background: Dementia is a collective term for several diseases that affect memory, other cognitive abilities, and behavior. These diseases can seriously interfere with people’s ability of daily living. This is not a normal phenomenon of aging. With the increasing prevalence of dementia in the elderly, the importance of dementia as a comorbidity of hypertension is increasing. However, several questions regarding the link between hypertension and dementia remain unresolved. This study aimed to determine Orientation-Memory-Concentration-Test (OMCT) can be used to assess cognitive function in the elderly as an early step in the early detection of dementia. Subjects and Method: This was a comparative study using a case-control design. The study was conducted in Jetis Sub-District, Yogyakarta from September 2019 to June 2020. A total sample of 110 of elderly was divided into two groups 42 elderly (case), and 68 elderly (control) selected by consecutive sampling using the Mini-Mental State Examination (MMSE), Clock-Drawing Test (CDT) and Orientation-Memory-Concentration Test (OMCT). The dependent variables were the sensitivity and specificity level of the OMCT instrument while the scores of the MMSE. The independent variable was CDT instruments. The collected data will then be processed by diagnostic analysis followed by analysis of ROC and Youden’s index to determine the optimal cut off. Respondents are categorized as having impaired cognitive function if the MMSE (cut off ≤ 24) or CDT (cut off <18) shows a positive result. Results: 110 elderlies were involved. A total of 42 elderlies were included in the case population, and 68 elderlies were included in the control population. In the total OMCT population (cut off> 11) it has a sensitivity (29%) and specificity (97%) to the combination of MMSE and CDT. In populations with hypertension OMCT (cut off> 2.5) has sensitivity (68%) with specificity (46%). In a population without hypertension OMCT (cut off> 7) has a sensitivity (55%) and specificity (90%) to the combination of MMSE and CDT. Conclusion: OMCT can be used as a screening tool for cognitive dysfunction in older people with hypertension because of its short duration, ease of use, and can be used in patients with visual impairments. Keywords: Dementia, cognitive dysfunction, OMCT, 6-CIT. Correspondence: Darren Eduardo William. School of medicine Universitas Kristen Duta Wacana, Yogyakarta. Jl. Dr. Wahidin Sudirohusodo 5-25 Yogyakarta 55224, Indonesia. Email: [email protected]. Mobile: 0813-4136-9999 DOI: https://doi.org/10.26911/the7thicph.05.17

Exploring Time of Day Effects on Mini-Mental State Examination Performance in Alzheimer's Disease and Age-Associated Cognitive Decline

2005 ◽  
Vol 6 (3) ◽  
pp. 212-218 ◽  
Author(s):  
Michelle A. Brown ◽  
Margaret Newson ◽  
Judy Haworth ◽  
Gordon K. Wilcock
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Decline ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Neuropsychological Test ◽  
Time Of Day ◽  
Future Research ◽  
Cognitive Screening ◽  
State Examination

AbstractNeuropsychological assessment plays a prominent role in the diagnosis of Alzheimer's disease (AD) and other cognitive impairments. Increasingly, neuropsychological test results are also used to guide clinicians in the prescription of anti-dementia medication. There is evidence to suggest that the cognitive ability of an individual with AD may vary over the course of a day. If time of day can influence an individual's performance on cognitive tests, then it could potentially affect his or her diagnosis and eligibility for treatment. This study set out to explore the effect of time of day on Mini-Mental State Examination (MMSE) performance in individuals with AD and Age-Associated Cognitive Decline (AACD). No significant effect of time of day (TOD) on Folstein MMSE performance was found. However, some interesting results were highlighted and future research suggested. Overall, the study does not provide evidence that time of day needs to be considered when interpreting the result of a short cognitive screening test.

The value of the Mini Mental State examination in Nigerian epileptics

2005 ◽  
Vol 35 (2) ◽  
pp. 108-108 ◽  
Author(s):  
I Imam ◽  
A Ogunniyi
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Dysfunction ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Item Recall ◽  
State Examination

This study assessed the role of the Mini Mental State examination (MMSE) in detecting cognitive impairment in Nigerian epileptics. The performance of 65 epileptics on the MMSE was compared with that in 65 age- and education-matched controls. There were significantly more epileptics than controls with cognitive dysfunction and the epileptics also had significantly worse scores on the MMSE. The tests of attention, three-item recall and reading were the aspects of the MMSE that were most impaired in the epileptics.

scholarly journals Assessment of Dementia in Individuals with Dual Sensory Loss: Application of a Tactile Test Battery

2018 ◽  
Vol 8 (1) ◽  
pp. 12-22 ◽  
Author(s):  
Peter Bruhn ◽  
Jesper Dammeyer
Keyword(s):  
Mental State ◽  
Cognitive Abilities ◽  
Cognitive Assessment ◽  
Mini Mental State Examination ◽  
Test Battery ◽  
Sensory Loss ◽  
Elderly Individuals ◽  
Dual Sensory Loss ◽  
And Control ◽  
State Examination

Background/Aims: Individuals with dual sensory loss (DSL) are more likely to experience cognitive decline with age than individuals without sensory loss. Other studies have pointed to the challenges in assessing cognitive abilities in individuals with DSL, as most existing instruments rely on use of vision and hearing. The aim of this study was to develop and evaluate a Tactile Test Battery (TTB) for cognitive assessment in individuals with DSL. Method: Twenty elderly individuals with DSL, 20 with diagnosed dementia, and 20 without dementia or DSL (controls) completed the following tactile tests developed for the present study: Spatial learning, Spatial recall, Tactile form board, Clock reading, and Naming. The participants with dementia and controls also completed the Mini-Mental State Examination (MMSE). Results: Overall, participants with dementia performed significantly worse on the tactile tests than participants with DSL and control participants. No significant differences on the tactile tests were found between participants with DSL and controls. The TTB and MMSE scores correlated significantly. Conclusion: The findings from this study of applying tactile tests for cognitive examination in individuals with DSL are promising. They indicate that symptoms of dementia can be differentiated from symptoms related to DSL.

Sign in / Sign up

Export Citation Format

Share Document