scholarly journals Lifetime Musical Training and Cognitive Performance in a Memory Clinic Population: A Cross-Sectional Study

2020 ◽  
pp. 102986492091863
Author(s):  
Daisy Fancourt ◽  
Katharina Geschke ◽  
Andreas Fellgiebel ◽  
Alexandra Wuttke-Linnemann
Keyword(s):  
Mental State ◽  
Mini Mental State Examination ◽  
Musical Training ◽  
Cognitive Impairments ◽  
Neuropsychological Test ◽  
Word List ◽  
Memory Clinic ◽  
Cross Sectional ◽  
Examination Score ◽  
State Examination

Background: Music training has been found to be beneficial for young and healthy participants but the associations between musical training and the cognitive functioning of elderly participants have not been reported consistently. We examined whether lifetime musical training is associated with neuropsychological performance in a memory clinic population of older patients. Methods: A total of 478 patients (54.2% female, mean age 73.70 ± 6.22, mean Mini Mental State Examination score 25 ± 3) were included in the cross-sectional analyses. All patients were referred to the memory clinic due to cognitive impairments. During the course of diagnosis, all patients underwent neuropsychological tests using the CERAD neuropsychological assessment battery. Patients provided information on whether they ever learned to play an instrument for at least five years in their life. Results: Neuropsychological test results differed based on musical training ( p = .042). Overall, there were no differences in any domains of cognitive functioning, other than that patients with musical training performed worse on word list memory ( p = .008). However, this relationship varied based on the extent of cognitive impairments. Patients who were cognitively unimpaired (Mini Mental State Examination score 27–30) and had musical training showed better word list learning, whereas patients with cognitive impairments (Mini Mental State Examination score < 27) and musical training performed worse in word list learning ( p = .042) and word list recall ( p = .045). Discussion: Overall, there was little evidence of associations between specific neuropsychological test results and musical training. Only in cognitively unimpaired patients was there evidence that musical training had beneficial associations. In patients with cognitive impairment, there were suggestions of negative associations with verbal memory. Future research should longitudinally investigate the beneficial effects of musical training in people with and without cognitive impairments.

Zur Anwendung der CES-D bei älteren Menschen: Dimensionsstruktur und Meßartefakte

Diagnostica ◽  
2000 ◽  
Vol 46 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Herbert Matschinger ◽  
Astrid Schork ◽  
Steffi G. Riedel-Heller ◽  
Matthias C. Angermeyer
Keyword(s):  
Mental State ◽  
Latent Class ◽  
Mini Mental State Examination ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Partial Credit ◽  
Examination Score ◽  
State Examination

Zusammenfassung. Beim Einsatz der Center for Epidemiological Studies Depression Scale (CES-D) stellt sich das Problem der Dimensionalität des Instruments, dessen Lösung durch die Konfundierung eines Teilkonstruktes (“Wohlbefinden”) mit Besonderheiten der Itemformulierung Schwierigkeiten bereitet, da Antwortartefakte zu erwarten sind. Dimensionsstruktur und Eignung der CES-D zur Erfassung der Depression bei älteren Menschen wurden an einer Stichprobe von 663 über 75-jährigen Teilnehmern der “Leipziger Langzeitstudie in der Altenbevölkerung” untersucht. Da sich die Annahme der Gültigkeit eines partial-credit-Rasch-Modells sowohl für die Gesamtstichprobe als auch für eine Teilpopulation als zu restriktiv erwies, wurde ein 3- bzw. 4-Klassen-latent-class-Modell für geordnete Kategorien berechnet und die 4-Klassen-Lösung als den Daten angemessen interpretiert: Drei Klassen zeigten sich im Sinne des Konstrukts “Depression” geordnet, eine Klasse enthielt jene Respondenten, deren Antwortmuster auf ein Antwortartefakt hinwiesen. In dieser Befragtenklasse wird der Depressionsgrad offensichtlich überschätzt. Zusammenhänge mit Alter und Mini-Mental-State-Examination-Score werden dargestellt. Nach unseren Ergebnissen muß die CES-D in einer Altenbevölkerung mit Vorsicht eingesetzt werden, der Summenscore sollte nicht verwendet werden.

scholarly journals Hubungan Lama Hemodialisis dengan Fungsi Kognitif pada Pasien yang Menjalani Hemodialisis Menggunakan Metode Mini Mental State Examination Ditinjau dari Kedokteran dan Islam

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Suci Purnama ◽  
Linda Armelia
Keyword(s):  
Mental State ◽  
Mini Mental State Examination ◽  
Cross Sectional ◽  
Consecutive Sampling ◽  
State Examination

Hemodialisis merupakan terapi pengganti ginjal pada penyakit ginjal kronik. Terdapat data statistik yang berbeda untuk prevalensi gangguan kognitif di Indonesia pada pasien yang menjalani hemodialisis mulai dari 20% - 47%. Penelitian ini menggunakan analitik korelatif dengan desain cross sectional yang dilakukan pada bulan Agustus 2018 di RS Anna Medika Bekasi dengan jumlah sampel sebanyak 102 responden yang diambil dengan cara consecutive sampling. Peneliti melakukan wawancara dengan menggunakan kuisioner Mini Mental State Examination (MMSE). Analisis data dengan menggunakan uji spearman. Fungsi kognitif pasien hemodialisis berdasarkan MMSE didapatkan penurunan fungsi kognitif ringan sebanyak 56 (54,9%), penurunan fungsi kognitif sedang sebanyak 13 (12,7%) dan tidak mengalami penurunan fungsi kognitif sebanyak 33 (32,4%). Hubungan antara lama hemodialisis dengan fungsi kognitif didapatkan p=0,002. Terdapat hubungan signifikan antara lama hemodialisis dengan fungsi kognitif pada pasien hemodialisis di RS Anna Medika

scholarly journals Hubungan Usia, Jenis Kelamin dan Status Anemia dengan Fungsi Kognitif pada Lanjut Usia

2020 ◽  
Vol 7 (1) ◽  
pp. 12-17
Author(s):  
Riza Firdaus
Keyword(s):  
Mental State ◽  
Mini Mental State Examination ◽  
Chi Square ◽  
Cross Sectional ◽  
State Examination

Menurunnya fungsi kognitif sangat mempengaruhi kualitas hidup lanjut usia. Faktor yang mempengaruhi adalah faktor fisiologis, psikologis dan lingkungan. Studi ini bertujuan untuk mengetahui hubungan usia, jenis kelamin dan status anemia dengan fungsi kognitif pada lanjut usia. Desain penelitian yaitu analitik observasional dengan pendekatan cross-sectional. Penelitian ini dilakukan di Panti Wredha Wening Wardoyo Semarang. Jumlah sampel yang didapatkan sebanyak 51 orang lanjut usia dengan total sampling. Variabel dependen adalah fungsi kognitif dan variabel independen adalah usia, jenis kelamin dan status anemia. Pemeriksaan fungsi kognitif diukur dengan instrumen Mini Mental State Examination (MMSE) dan pemeriksaan status anemia menggunakan haemometer dengan metode Sahli. Analisis data yang digunakan adalah menggunakan uji Chi Square. Hasil penelitian menunjukkan usia < 75 tahun meningkatkan risiko fungsi kognitif normal (OR = 6,480; 95% CI 1,844- 22,769; p = 0,002), jenis kelamin laki – laki (OR = 2,357; 95% CI 0,688- 8,075; p = 0,167) dan anemia ringan (OR = 2,821; 95% CI 0,831- 9,577; p = 0,091). Penelitian ini menyimpulkan bahwa fungsi kognitif pada lanjut usia dipengaruhi oleh usia, jenis kelamin dan status anemia.

scholarly journals Dopaminergic imaging and clinical predictors for phenoconversion of REM sleep behaviour disorder

Brain ◽  
2020 ◽  
Author(s):  
Dario Arnaldi ◽  
Andrea Chincarini ◽  
Michele T Hu ◽  
Karel Sonka ◽  
Bradley Boeve ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Mental State ◽  
Rem Sleep ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Bayesian Classifier ◽  
Examination Score ◽  
Sleep Behaviour ◽  
State Examination

Abstract This is an international multicentre study aimed at evaluating the combined value of dopaminergic neuroimaging and clinical features in predicting future phenoconversion of idiopathic REM sleep behaviour (iRBD) subjects to overt synucleinopathy. Nine centres sent 123I-FP-CIT-SPECT data of 344 iRBD patients and 256 controls for centralized analysis. 123I-FP-CIT-SPECT images were semiquantified using DaTQUANTTM, obtaining putamen and caudate specific to non-displaceable binding ratios (SBRs). The following clinical variables were also analysed: (i) Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale, motor section score; (ii) Mini-Mental State Examination score; (iii) constipation; and (iv) hyposmia. Kaplan-Meier survival analysis was performed to estimate conversion risk. Hazard ratios for each variable were calculated with Cox regression. A generalized logistic regression model was applied to identify the best combination of risk factors. Bayesian classifier was used to identify the baseline features predicting phenoconversion to parkinsonism or dementia. After quality check of the data, 263 iRBD patients (67.6 ± 7.3 years, 229 males) and 243 control subjects (67.2 ± 10.1 years, 110 males) were analysed. Fifty-two (20%) patients developed a synucleinopathy after average follow-up of 2 years. The best combination of risk factors was putamen dopaminergic dysfunction of the most affected hemisphere on imaging, defined as the lower value between either putamina (P &lt; 0.000001), constipation, (P &lt; 0.000001) and age over 70 years (P = 0.0002). Combined features obtained from the generalized logistic regression achieved a hazard ratio of 5.71 (95% confidence interval 2.85–11.43). Bayesian classifier suggested that patients with higher Mini-Mental State Examination score and lower caudate SBR asymmetry were more likely to develop parkinsonism, while patients with the opposite pattern were more likely to develop dementia. This study shows that iRBD patients older than 70 with constipation and reduced nigro-putaminal dopaminergic function are at high risk of short-term phenoconversion to an overt synucleinopathy, providing an effective stratification approach for future neuroprotective trials. Moreover, we provide cut-off values for the significant predictors of phenoconversion to be used in single subjects.

scholarly journals Definition and application of neuropsychological test battery to evaluate postoperative cognitive dysfunction

2015 ◽  
Vol 13 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Lívia Stocco Sanches Valentin ◽  
Ricardo Pietrobon ◽  
Wagner de Aguiar Junior ◽  
Ruth Pinto Camarão Rios ◽  
Mariane Galzerano Stahlberg ◽  
...  
Keyword(s):  
General Anesthesia ◽  
Cognitive Dysfunction ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Neuropsychological Test ◽  
Postoperative Cognitive Dysfunction ◽  
Test Battery ◽  
Cutoff Point ◽  
Neuropsychological Test Battery ◽  
State Examination

Objective To investigate the adequacy of the neuropsychological test battery proposed by the International Study of Postoperative Cognitive Dysfunction to evaluate this disorder in Brazilian elderly patients undergoing surgery under general anesthesia. Methods A neuropsychological assessment was made in patients undergoing non-cardiac surgery under general anesthesia, aged over 65 years, literate, with no history of psychiatric or neurological problems and score on the Mini Mental State Examination at or above the cutoff point for the Brazilian population (>18 or >23) according to the schooling level of the subject. Eighty patients were evaluated by a trained team of neuropsychologists up to 24 hours before elective surgery. Results Among the patients evaluated, one was excluded due to score below the cutoff point in the Mini Mental State Examination and two did not complete the test battery, thus remaining 77 patients in the study. The mean age was 69±7.5 years, and 62.34% of the subjects had ±4 years of study. The subjects had significantly lower averages than expected (p<0.001) for normative tables on neuropsychological tests. Conclusion The study demonstrated the applicability of the instruments in the Brazilian elderly and low schooling level population, but suggested the need to determine cutoff points appropriate for these individuals, ensuring the correct interpretation of results. This battery is relevant to postoperative follow-up evaluations, favoring the diagnosis of postoperative cognitive dysfunction in patients undergoing different types of surgery and anesthetic techniques.

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