scholarly journals Lung cysts in chronic paracoccidioidomycosis

2013 ◽  
Vol 39 (3) ◽  
pp. 368-372 ◽  
Author(s):  
Andre Nathan Costa ◽  
Edson Marchiori ◽  
Gil Benard ◽  
Mariana Sponholz Araujo ◽  
Bruno Guedes Baldi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Retrospective Analysis ◽  
Interstitial Pneumonia ◽  
Langerhans Cell Histiocytosis ◽  
Lung Diseases ◽  
Lung Parenchyma ◽  
Langerhans Cell ◽  
Lung Cysts ◽  
Cystic Lung ◽  
Lymphocytic Interstitial Pneumonia

On HRCT scans, lung cysts are characterized by rounded areas of low attenuation in the lung parenchyma and a well-defined interface with the normal adjacent lung. The most common cystic lung diseases are lymphangioleiomyomatosis, Langerhans cell histiocytosis, and lymphocytic interstitial pneumonia. In a retrospective analysis of the HRCT findings in 50 patients diagnosed with chronic paracoccidioidomycosis, we found lung cysts in 5 cases (10%), indicating that patients with paracoccidioidomycosis can present with lung cysts on HRCT scans. Therefore, paracoccidioidomycosis should be included in the differential diagnosis of cystic lung diseases.

scholarly journals Diffuse cystic lung diseases: differential diagnosis

2017 ◽  
Vol 43 (2) ◽  
pp. 140-149 ◽  
Author(s):  
Bruno Guedes Baldi ◽  
Carlos Roberto Ribeiro Carvalho ◽  
Olívia Meira Dias ◽  
Edson Marchiori ◽  
Bruno Hochhegger
Keyword(s):  
Lung Diseases ◽  
Laboratory Findings ◽  
Lung Cysts ◽  
Lung Lobe ◽  
Cystic Lung ◽  
Pulmonary Langerhans Cell Histiocytosis ◽  
Pulmonary Cysts ◽  
Lymphocytic Interstitial Pneumonia ◽  
Definition Of ◽  
Airway Walls

ABSTRACT Diffuse cystic lung diseases are characterized by cysts in more than one lung lobe, the cysts originating from various mechanisms, including the expansion of the distal airspaces due to airway obstruction, necrosis of the airway walls, and parenchymal destruction. The progression of these diseases is variable. One essential tool in the evaluation of these diseases is HRCT, because it improves the characterization of pulmonary cysts (including their distribution, size, and length) and the evaluation of the regularity of the cyst wall, as well as the identification of associated pulmonary and extrapulmonary lesions. When combined with clinical and laboratory findings, HRCT is often sufficient for the etiological definition of diffuse lung cysts, avoiding the need for lung biopsy. The differential diagnoses of diffuse cystic lung diseases are myriad, including neoplastic, inflammatory, and infectious etiologies. Pulmonary Langerhans cell histiocytosis, lymphangioleiomyomatosis, lymphocytic interstitial pneumonia, and follicular bronchiolitis are the most common diseases that produce this CT pattern. However, new diseases have been included as potential determinants of this pattern.

Cystic Lung Disease

Chest Imaging ◽  
2019 ◽  
pp. 429-433
Author(s):  
Juliana Bueno
Keyword(s):  
Lung Disease ◽  
Langerhans Cell Histiocytosis ◽  
Normal Lung ◽  
Lung Cysts ◽  
Cystic Lung ◽  
Pulmonary Langerhans Cell Histiocytosis ◽  
Cystic Lung Disease ◽  
Lymphocytic Interstitial Pneumonia ◽  
Cavitary Disease ◽  
Diffuse Lung

A lung cyst is a round parenchymal lucency or low-attenuating area with a well-defined interface with adjacent normal lung and surrounded by an epithelial or fibrous wall that is often less than 2 mm in thickness. Diseases that manifest with lung cysts comprise a limited but well known group of entities. Classic diseases manifesting with diffuse lung cysts include pulmonary Langerhans cell histiocytosis (PLCH), lymphangioleiomyomatosis (LAM), lymphocytic interstitial pneumonia (LIP) and Birt-Hogg-Dubé syndrome. However, it is important to recognize other conditions that may mimic cystic lung disease, such as pneumatoceles, tracheobronchial papillomatosis, cavitary disease (e.g. tuberculosis, fungal infection), bronchiectasis, and emphysema. Differentiation between true cysts and cyst mimics may be difficult, and may rely on identification of ancillary findings.

Primary cerebral non-Langerhans cell histiocytosis: MRI and differential diagnosis

2002 ◽  
Vol 44 (9) ◽  
pp. 759-763 ◽  
Author(s):  
U. Ernemann ◽  
M. Skalej ◽  
M. Hermisson ◽  
M. Platten ◽  
R. Jaffe ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell

Obstructive Lung Diseases

2016 ◽  
pp. 741-746
Author(s):  
Vivek N. Iyer
Keyword(s):  
Differential Diagnosis ◽  
Interstitial Lung Disease ◽  
General Population ◽  
Lung Disease ◽  
Pulmonary Edema ◽  
Lung Diseases ◽  
Lung Parenchyma ◽  
Obstructive Lung Diseases ◽  
Lung Malignancies

An estimated 1 in 3,000 to 1 in 4,000 persons in the general population have a diagnosis of interstitial lung disease (ILD), and ILDs account for about 15% of all consultations for general pulmonologists. These diseases encompass a group of heterogeneous lung conditions characterized by diffuse involvement of the lung parenchyma and pulmonary interstitium. By convention, infections, pulmonary edema, lung malignancies, and emphysema are excluded, but they should be carefully considered as part of the differential diagnosis.

Pulmonary Langerhans Cell Histiocytosis

2020 ◽  
Vol 41 (02) ◽  
pp. 269-279
Author(s):  
Brian Shaw ◽  
Michael Borchers ◽  
Dani Zander ◽  
Nishant Gupta
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Treatment Options ◽  
Skin Lesions ◽  
Langerhans Cell ◽  
Mitogen Activated Protein Kinase ◽  
Myeloid Neoplasm ◽  
Cystic Lung ◽  
Pulmonary Langerhans Cell Histiocytosis ◽  
Mitogen Activated Protein ◽  
The Central Nervous System

AbstractPulmonary Langerhans cell histiocytosis (PLCH) is a diffuse cystic lung disease that is strongly associated with exposure to cigarette smoke. Recently, activating pathogenic mutations in the mitogen-activated protein kinase pathway have been described in the dendritic cells in patients with PLCH and have firmly established PLCH to be an inflammatory myeloid neoplasm. Disease course and prognosis in PLCH are highly variable among individual patients, ranging from spontaneous resolution to development of pulmonary hypertension and progression to terminal respiratory failure. A subset of patients with PLCH may have extrapulmonary involvement, typically involving the skeletal system in the form of lytic lesions, skin lesions, or the central nervous system most commonly manifesting in the form of diabetes insipidus. Smoking cessation is the cornerstone of treatment in patients with PLCH and can lead to disease regression or stabilization in a substantial proportion of patients. Further insight into the underlying molecular pathogenesis of PLCH has paved the way for the future development of disease-specific biomarkers and targeted treatment options directed against the central disease-driving mutations.

Langerhans cell histiocytosis in childhood – Review, symptoms in the oral cavity, differential diagnosis and report of two cases

2014 ◽  
Vol 42 (2) ◽  
pp. 93-100 ◽  
Author(s):  
Vlasta Merglová ◽  
Daniel Hrušák ◽  
Ludmila Boudová ◽  
Petr Mukenšnabl ◽  
Eva Valentová ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Oral Cavity ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell

scholarly journals A-CYST-ANCE ON LUNG DISEASES: A CASE OF PULMONARY LANGERHANS CELL HISTIOCYTOSIS

CHEST Journal ◽  
2020 ◽  
Vol 158 (4) ◽  
pp. A1139
Author(s):  
Byung Soo Yoo ◽  
Francis Pham ◽  
Sukhpreet Kaur ◽  
Marina Johnston
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Lung Diseases ◽  
Langerhans Cell ◽  
Pulmonary Langerhans Cell Histiocytosis

scholarly journals Rare Lung Diseases III: Pulmonary Langerhans’ Cell Histiocytosis

2010 ◽  
Vol 17 (3) ◽  
pp. e55-e62 ◽  
Author(s):  
Stephen C Juvet ◽  
David Hwang ◽  
Gregory P Downey
Keyword(s):  
Cell Biology ◽  
Langerhans Cell Histiocytosis ◽  
Lung Diseases ◽  
Treatment Options ◽  
Langerhans Cell ◽  
Major Theme ◽  
Pulmonary Langerhans Cell Histiocytosis ◽  
Current Series ◽  
Pulmonary Manifestations ◽  
Rare Lung Diseases

Pulmonary Langerhans’ cell histiocytosis (PLCH) is an unusual cystic lung disease that is also characterized by extrapulmonary manifestations. The current review discusses the presenting features and relevant diagnostic testing and treatment options for PLCH in the context of a clinical case. While the focus of the present article is adult PLCH and its pulmonary manifestations, it is important for clinicians to distinguish the adult and pediatric forms of the disease, as well as to be alert for possible extrapulmonary complications. A major theme of the current series of articles on rare lung diseases has been the translation of insights gained from fundamental research to the clinic. Accordingly, the understanding of dendritic cell biology in this disease has led to important advances in the care of patients with PLCH.

scholarly journals Pulmonary Langerhans cell histiocytosis with inguinal abscess: Unusual presentation

2020 ◽  
Vol 29 (1) ◽  
pp. 64-66
Author(s):  
Kamarul Naim Mohd Hirmizi ◽  
Nurul Yaqeen Mohd Esa ◽  
Mardiana Abdul Aziz ◽  
Nor Salmah Bakar ◽  
Mohammad Hanafiah
Keyword(s):  
Lymph Node ◽  
Langerhans Cell Histiocytosis ◽  
Respiratory Symptoms ◽  
Inguinal Lymph Node ◽  
Langerhans Cell ◽  
Histopathological Analysis ◽  
Intermittent Fever ◽  
Cystic Lung ◽  
Pulmonary Langerhans Cell Histiocytosis ◽  
History Of

We report a case of a 30-year-old man who was treated as recurrent right inguinal abscess following a 2-month history of right inguinal swelling and intermittent fever with no respiratory symptoms. Resection of his right inguinal lymph node and the histopathological analysis revealed the diagnosis of Langerhans cell histiocytosis. In addition, the CT of the thorax showed presence of bilateral cystic lung changes consistent with pulmonary Langerhans cell histiocytosis.

DIFFERENTIAL DIAGNOSTICS OF NON-SPECIFIC INTERSTITIAL PNEUMONIA

2020 ◽  
Vol 2 (1) ◽  
pp. 50-52
Author(s):  
Nargiza Makhmatmuradova ◽  
◽  
Olga Ibadova ◽  
Parvina Zikriyaeva
Keyword(s):  
Differential Diagnosis ◽  
Interstitial Pneumonia ◽  
Lung Diseases ◽  
Clinical Presentation ◽  
Differential Diagnostics ◽  
Hospital Treatment ◽  
Case Histories ◽  
Allergic Alveolitis ◽  
Nonspecific Interstitial Pneumonia ◽  
Exogenous Allergic Alveolitis

A retrospective analysis of case histories of 82 patients with nonspecific interstitial pneumonia, 24 patients with idiopathic pulmonary fibrosis, 8 with exogenous allergic alveolitis, 12 with systemic scleroderma and 6 with drug pneumonia was carried out in hospital treatment in the pulmonology department of the Samarkand city medical hospital in 2010-2019 years. It has been established that in the differential diagnosis of nonspecific interstitial pneumonia and other lung diseases, particular attention should be paid to the anamnesis, clinical presentation and CT signs

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