scholarly journals Comparison of the use of screening tools for evaluating cognitive impairment in patients with Parkinson's disease

2016 ◽  
Vol 10 (4) ◽  
pp. 344-350 ◽  
Author(s):  
Carlos Henrique Ferreira Camargo ◽  
Eduardo de Souza Tolentino ◽  
Augusto Bronzini ◽  
Marcelo de Araújo Ladeira ◽  
Ronilson Lima ◽  
...  

ABSTRACT Background: Screening tests have been used for cognitive deficits in Parkinson's disease (PD). Objective: This study compared the Montreal Cognitive Assessment (MoCA) test, the Mini-Mental State Examination (MMSE) and the clock drawing test for this purpose. Methods: A total of 50 patients with PD were selected, 41 (82%) were diagnosed with dementia by the criteria of the Movement Disorder Society. The test Scales for Outcomes in Parkinson's Disease-Cognition (SCOPA-Cog) was used as the gold standard in comparison with the screening tests. Results: The MoCA test (AUC=0.906) had a sensitivity of 87.80% and specificity of 88.89%. When the MMSE was associated with the clock drawing test (AUC=0.936), it had a specificity of 66.67% and sensitivity of up to 97.56%. Conclusion: The study suggests that the MoCA test can be a good screening test in PD. However, MMSE associated with the clock drawing test may be more effective than the MoCA test.

2014 ◽  
Vol 72 (12) ◽  
pp. 913-918 ◽  
Author(s):  
Ivan Aprahamian ◽  
Marcia Radanovic ◽  
Paula Villela Nunes ◽  
Rodolfo Braga Ladeira ◽  
Orestes Vicente Forlenza

There is limited data regarding the cognitive profile from screening tests of older adults with bipolar disorder (BD) with dementia. Objective To investigate the Clock Drawing Test (CDT) among older adults with BD with and without Alzheimer’s disease (AD). Method 209 older adults (79 with BD without dementia and 70 controls; 60 with AD, being 27 with BD) were included to evaluate the performance of three CDT scoring scales, beyond the Mini-Mental State Examination (MMSE) and verbal fluency (VFT). Results Patients with BD without dementia presented with lower scores in MMSE, VF and one CDT scoring scale than controls. Patients with BD and AD presented with lower scores in VF and CDT scoring scales than patients with only AD. All CDT scales presented similar sensitivity and specificity for BD and non-BD groups. Conclusion Elderly subjects with BD showed greater impairment in CDT in both groups of normal cognition and AD.


2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Maria Francesca De Pandis ◽  
Manuela Galli ◽  
Sara Vimercati ◽  
Veronica Cimolin ◽  
Maria Vittoria De Angelis ◽  
...  

Aims. The realization of an experimental set-up for the quantitative and objective description of drawing using optoelectronic systems, which could be used when a quantification of the realization of specific drawing tests is required.Methods. Healthy subjects, subjects with Parkinson's Disease and subjects with Parkinson's Disease and Dementia were evaluated by the Mini Mental Scale Evaluation and by a new approach to the Clock Drawing Test, based on an optoelectronic acquisition. The new protocol hereby described aims to define a parameter related to the movement kinematics in the Clock Drawing test execution.Results. The experimental set-up revealed to be valid introducing new objective measurements beside the subjective Clock Drawing Test. This paper suggests the applicability of this protocol to other fields of motor and cognitive valuation, as well as the introduction of new parameters related to the graphic movement.


2015 ◽  
Vol 27 (10) ◽  
pp. 1649-1660 ◽  
Author(s):  
Lynnette Pei Lin Tan ◽  
Nathan Herrmann ◽  
Brian J. Mainland ◽  
Kenneth Shulman

ABSTRACTBackground:Studies have shown the clock-drawing test (CDT) to be a useful screening test that differentiates between normal, elderly populations, and those diagnosed with dementia. However, the results of studies which have looked at the utility of the CDT to help differentiate Alzheimer's disease (AD) from other dementias have been conflicting. The purpose of this study was to explore the utility of the CDT in discriminating between patients with AD and other types of dementia.Methods:A review was conducted using MEDLINE, PsycINFO, and Embase. Search terms included clock drawing or CLOX and dementia or Parkinson's Disease or AD or dementia with Lewy bodies (DLB) or vascular dementia (VaD).Results:Twenty studies were included. In most of the studies, no significant differences were found in quantitative CDT scores between AD and VaD, DLB, and Parkinson's disease dementia (PDD) patients. However, frontotemporal dementia (FTD) patients consistently scored higher on the CDT than AD patients. Qualitative analyses of errors differentiated AD from other types of dementia.Conclusions:Overall, the CDT score may be useful in distinguishing between AD and FTD patients, but shows limited value in differentiating between AD and VaD, DLB, and PDD. Qualitative analysis of the type of CDT errors may be a useful adjunct in the differential diagnosis of the types of dementias.


2018 ◽  
Vol 18 (2) ◽  
pp. 123-131 ◽  
Author(s):  
Cettina Allone ◽  
Viviana Lo Buono ◽  
Francesco Corallo ◽  
Lilla Bonanno ◽  
Rosanna Palmeri ◽  
...  

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