scholarly journals Evaluation of Mini-Mental State Examination scores according to different age and education strata, and sex, in a large Brazilian healthy sample

2009 ◽  
Vol 3 (2) ◽  
pp. 88-93 ◽  
Author(s):  
Renata Kochhann ◽  
Maria Otília Cerveira ◽  
Cláudia Godinho ◽  
Analuiza Camozzato ◽  
Márcia Lorena F. Chaves

Abstract Until better measures have been accepted for wider use, the Mini-Mental State Examination (MMSE) will continue to be utilized. In this context, knowledge on characteristics and determinants of its distribution for the Brazilian population are particularly valuable. The present study aimed to evaluate, based on multivariate analysis, the independent effect of age, educational level and sex, and their interactions, on MMSE scores in a healthy sample. Methods: Demographic data and scores on the MMSE of 1,553 healthy individuals were analyzed. The sample was grouped according to age and education. Results: The sample was composed of 963 females (62%), mean age ±SD was 49.6±20.7 yrs (range 20 to 92 yrs). The mean years of education ±SD was 8.9±5.5 yrs (range 0 to 28 yrs). The mean score ±SD on the MMSE was 27.3±2.7 (range 15 to 30). A significant effect of the interaction between education and sex (p=0.011), and also between education and age was observed (p=0.003). An independent effect of education (p<0.001) and age (p<0.001) was found. Participants from the higher educated group presented higher MMSE scores than the other groups. Younger adults presented higher MMSE scores than the other age groups. Conclusions: We observed an effect of education and age on MMSE scores. Younger individuals and higher educated participants presented higher scores.

Author(s):  
Élcio Alves Guimarães ◽  
Kennedy Rodrigues Lima ◽  
Flávia Fernandes Oliveira ◽  
Renato Mota da Silva ◽  
Lucas Resende Sousa ◽  
...  

Background: Aging is a dynamic, progressive and physiological process, accompanied by morphological and functional changes, as well as biochemical and psychological changes, resulting in a decrease in the functional reserve of organs and system. With aging, functional losses occur, so the elderly have a greater predisposition to falls. Objective: To compare the propensity to falls between elderly men and women correlating with the level of cognition and balance. Methods: The sample consisted of 60 elderly people, of which 30 were male and 30 were female both aged 65 to 80 years. The propensity to falls was assessed using the “Timed Up and Go” and “Functional Reach” tests, and the state of cognition was assessed by the test “Mini-Mental State Examination”. Results: The results obtained with Time Up and Go, Functional Reach and the Mini-Mental State Examination, indicated that, as the values of one of the variables increase, the values of the other variable increase too; as the values of one of the variables decrease, the values of the other variable increase too. Conclusions: It can be concluded that there was no increased risk of fall when compared the genders; but the female presented altered cognitive deficit.


2016 ◽  
Vol 24 (1) ◽  
pp. 30-35 ◽  
Author(s):  
Swapon Kumar Ghose ◽  
Ahmed Hossain Chowdhury ◽  
ATM Hasibul Hasan ◽  
Muhammad Zillur Rahman Khan ◽  
ASM Rezaul Karim ◽  
...  

Objective: The aim of the present study was to compare the efficacy of modified Bangla version of mini mental state examination (MMSE-B) with mini mental state examination (MMSE) for using among Bangladeshi healthy elderly.Methods: This is a descriptive type of observational study carried out in Department of Neurology, Dhaka Medical College Hospital, Dhaka, from January to December of 2013. A total of 200 healthy elderly (patient attendants at the clinic) who met the inclusion criteria, were interviewed using a structured questionnaire containing information on age, sex, residence, educational backgrounds and questions set at MMSE English version (MMSE-E) and modified Bangla version for MMSE-B (Figure-1). MMSE and MMSE-B both were applied in 1:1 ration. The literate people were asked whether they are comfortable to answer in English (MMSE-E) or they would like the translated form and we applied the form of MMSE (MMSE-T) according to their wish. But in other group of people the modified Bangla version (MMSE-B) was used irrespective of level of education.Results: The mean age at presentation was 58.1±7.8 and 94% were within 50-70 years of age. Male were more common (80, 66) in both the groups and most of them belonging to rural areas. MMSE-B were mostly employed on people having only primary level of education (up to class five, n=80) or no education (n=2), whereas MMSE-E were employed up on people having a level of education higher than class five (n=96). Every question in each item of cognitive domain correlated well (correlation co-efficient range from 0.801- 0.971) except the 7th (correlation co-efficient 0.418) which had higher mean score for MMSE-B than those of MMSE-E (0.90 versus 0.54). The mean score of MMSE-B was greater than the mean score of MMSE-E for most of questions except the 1st question that is related to orientation of time. The mean of total score in MMSE-E and MMSE-B were 24.04 and 24.91 respectively with a correlation co-efficient of 0.940.Conclusion: MMSE-B is comparable to MMSE and it is even better in some segments of cognitive assessment for using among Bangladeshi people irrespective of level of education.J Dhaka Medical College, Vol. 24, No.1, April, 2015, Page 30-35


2016 ◽  
Vol 10 (supp1) ◽  
pp. 61-74 ◽  
Author(s):  
Deusivania Vieira da Silva Falcão ◽  
Maycoln Leoni Martins Teodoro ◽  
Júlia Sursis Nobre Ferro Bucher-Maluschke

In this regard, investigating these aspects might facilitate the evaluation of family relations and the development of interventions that create, keep, restore, or enhance the skills families need to better deal with the disease. Based on this information, the objective of this chapter is to present and discuss investigative research on family cohesion and hierarchy from the perspective of caregiver daughters of elderly with Alzheimer’s in four situations: before the disease, currently, in conflict, and ideally. 32 women caretakers and their respective parents (6 fathers and 26 mothers) diagnosed with possible or probable AD participated in the survey. The instruments used were the Mini-Mental State Examination (MMSE) in an Open Interview with a Semi-Structured Script, and the Family System Test (FAST). We observed that before onset of the disease, the caregivers generally perceived themselves to have more hierarchy than their siblings, χ2(2) = 4.92, p < .10. The current situation showed a greater number of caregivers in higher hierarchical positions than their siblings (72%), and a lesser number of siblings than expected in higher hierarchical positions than the caregivers, χ2(2) = 18.32, p < .001. The ideal representation showed that most caregivers did not want themselves or any of their siblings to have more power than the other (66.7%), χ2(2) = 14.89, p < .001. Comparing conflict representations to ideal representations showed that family members demonstrated lower cohesion in conflict situations than in ideal situations, z = -2.86, p < .01.


2016 ◽  
Vol 32 (2) ◽  
pp. 91-97
Author(s):  
Swapon Kumar Ghose ◽  
Kazi Gias Uddin Ahmed ◽  
Ahmed Hossian Chowdhury ◽  
ATM Hasibul Hasan ◽  
Muhammad Zillur Rahman Khan ◽  
...  

Background: The aim of our study was to determine whether modified Bangla version (MMSE-B) is as effective as mini mental state examination (MMSE) tool for use in Bangladeshi people. Methods: This descriptive observational study was carried out in Department of Neurology, DMCH from January 2013 to December 2013. A total 200 healthy adults (patient attendants at the clinic) who met the inclusion criteria, were interviewed using a structured questionnaire containing information on age, sex, residence, educational backgrounds and questions set at MMSE English version (MMSE-E) and modified Bangla version for MMSE-B (Figure-1). MMSE and MMSE-B both were applied in 1:1 ration. The literate people were asked whether they are comfortable to answer in English (MMSE-E) or they would like the translated form and we applied the form of MMSE (MMSE-T) according to their wish. But in other group of people the modified Bangla version (MMSE-B) was used irrespective of level of education. Result: The mean age at presentation was 58.1±7.8 and 94% were within 50-70 years of age. Male were more common (80, 66) in both the groups and most of them belonging to rural areas. MMSE-B were mostly employed on people having only primary level of education (up to class five, n=80) or no education (n=2), whereas MMSE-E were employed up on people having a level of education higher than class five (n=96). Every question in each item of cognitive domain correlated well (correlation co-efficient range from 0.801- 0.971) except the 7th (correlation co-efficient 0.418) which had higher mean score for MMSE-B than those of MMSE-E (0.90 versus 0.54). The mean score of MMSEB was greater than the mean score of MMSE-E for most of questions except the 1st question that is related to orientation of time. The mean of total score in MMSE-E and MMSE-B were 24.04 and 24.91 respectively with a correlation co-efficient of 0.940. Conclusion: MMSE-B is adaptable for use in Bangladeshi people irrespective of level of education. Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 91-97


2019 ◽  
Vol 188 (12) ◽  
pp. 2202-2212
Author(s):  
Alden L Gross ◽  
Alexandra M Kueider-Paisley ◽  
Campbell Sullivan ◽  
David Schretlen ◽  

Abstract The Mini-Mental State Examination (MMSE) is one of the most widely used cognitive screening tests in the world. However, its administration and content differs by country and region, precluding direct comparison of scores across different versions. Our objective was to compare 2 methods of deriving comparable scores across versions of the MMSE. Between 1981 and 2012, investigators in the International Neuropsychological Normative Database Initiative collected MMSE scores on 122,512 persons from 47 studies conducted in 35 countries. We used MMSE data from 80,559 adults aged 41–99 years from 22 studies that provided item-level response data. We first equated 14-point, 15-point, 18-point, 19-point, and 23-point versions of the MMSE to the original 30-point version using coarse equipercentile equating methods that preserved differences across continents, age groups, and durations (years) of education. We then derived more precise item response theory–based scores using item-level responses to MMSE component items. We compared the 2 score-equating approaches using correlation and Bland-Altman plots. Both test-equating approaches were highly correlated with each other (r = 0.73) and with raw MMSE point totals. Bland-Altman plots revealed minimal evidence of systematic differences between the approaches. Our findings support the use of equipercentile equating when item-level data are unavailable to facilitate development of international test norms.


2010 ◽  
Vol 4 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Renata Kochhann ◽  
Juliana Santos Varela ◽  
Carolina Saraiva de Macedo Lisboa ◽  
Márcia Lorena Fagundes Chaves

Abstract The increase in life expectancy can influence the prevalence of dementias in the population. Instruments that evaluate cognitive functions such as the Mini Mental State Examination (MMSE) are necessary for the investigation of dementia. The supposition that patient score on the MMSE can be influenced by academic level points to the need for establishing cut-off values that take into account educational level. The aim of this study was to review MMSE cut-off values adjusted for schooling in a large southern Brazilian sample. Method: Demographic data and MMSE scores of 968 subjects, of which 162 were dementia patients and 806 healthy participants, were analyzed. The sample was grouped according to education. The cut-off values were established by ROC Curve analysis. Results: The total sample mean age was 70.6±7.3 years, and the mean years of education was 7.2±5.3. The cut-off score of 23 points (sensitivity=86%, specificity=83%) was observed as the optimal level to detect dementia on the MMSE instrument for the overall sample. Regarding level of schooling, the cut-off values were: 21 for the illiterate group (sensitivity=93%, specificity=82%), 22 for the low education group (sensitivity=87%, specificity=82%), 23 for the middle education group (sensitivity=86%, specificity=87%) and 24 for the high education group (sensitivity=81%, specificity=87%). Conclusions: The cut-off values revealed by this analysis, and adjusted for level of schooling, can improve the clinical evaluation of cognitive deficits.


2016 ◽  
Vol 22 (1) ◽  
pp. 5 ◽  
Author(s):  
Mia Rademeyer ◽  
Pierre Joubert

<strong>Background:</strong> Cognitive impairment is a core feature of schizophrenia that also has strong prognostic significance. In most clinical settings comprehensive neuropsychological testing to detect cognitive impairment in schizophrenia patients is not readily available, but because cognitive deficits in schizophrenia are clinically important it would be useful to detect or at least screen for them in a clinical setting. Unfortunately there are no validated, brief screening instruments for the detection of cognitive impairment in schizophrenia. Nevertheless, the Montreal Cognitive Assessment Test (MoCA) and the Mini-Mental State Examination (MMSE) show promise in this regard. The objective of this study was to compare the results of the MMSE and MoCA in a group of outpatient schizophrenia sufferers to contribute to research into the instruments’ potential usefulness as screening tools for cognitive impairment in schizophrenia. <strong></strong><p><strong>Method:</strong> The Afrikaans versions of the MMSE and MoCA were administered to Afrikaansspeaking adult outpatients. Participants had at least seven years of formal education and had been in partial or full remission for at least 3 months. The MMSE and MoCA scores for each participant were matched and compared using the non-parametric Wilcoxon matched pairs test. <strong></strong></p><p><strong>Results:</strong> The sample consisted of 30 Afrikaans-speaking outpatients with schizophrenia. The mean MMSE score was 27.17 ± 2.64, and the mean MoCA score was 22.53 ± 3.91. There was a statistically significant difference between participants’ performance on the MMSE and MoCA tests (<em>p</em> = 0.000008). <strong></strong></p><p><strong>Conclusion:</strong> Compared to the MMSE, the MoCA may be a more useful instrument to detect cognitive impairment in patients with schizophrenia. Further studies are required.</p>


2019 ◽  
Vol 7 (2) ◽  
pp. 33438
Author(s):  
Jénifer Carolina Fernandes ◽  
Robson Ruiz Olivoto

AIMS: Our objective was to compare the levels of effect of flexibility and balance beyond the cognitive aspect of two groups of active and irregularly active elderly women. METHODS: The sample consisted of 24 elderly women in the age group of 60 and 75 years old, divided into two groups, Active elderly group (GA) composed of elderly women classified as active, and Group of irregularly active elderly (GI) composed of elderly women classified as irregularly active. We used the International Physical Activity Questionnaire (IPAQ) and the Sit and Go and Berg Balance Scale tests and the Mental State Mini Exam (MSME). RESULTS: Our data were treated through descriptive and comparative statistics, through the ANOVA one-way test, with Tukey’s posttest, Pearson’s Correlation and Student’s test for non-paired samples. The data were grouped and presented as mean and standard deviation of the mean. Our results showed no correlation between levels of flexibility and balance with the Mini Mental State Examination. The GA presented better results in the tests of flexibility and balance when compared to the GI. CONCLUSIONS: The GA presented better results in the variables flexibility and balance when compared to the GI, which allows us to conclude that the regular practice of physical exercises by GA was the determining factor for the group to obtain better results than the GI. In the cognitive factor, in our sample, physical exercise was not a determining factor.


1995 ◽  
Vol 25 (4) ◽  
pp. 841-848 ◽  
Author(s):  
G. J. Izaks ◽  
J. Gussekloo ◽  
K. M. T. Dermout ◽  
T. J. Heeren ◽  
G. J. Ligthart

SYNOPSISThe objective of this study was to describe over time the course of cognitive function of elderly without cognitive impairment and of elderly with different stages of impairment, and to assess if the change in cognitive function was dependent on the initial level of function. The Mini-Mental State Examination (MMSE) was used at two time points. The first assessment (MMSE-1) was part of a community-based study and was obtained from 871 subjects. For the second assessment (MMSE-2) a sample of 166 subjects was drawn from the subjects alive at follow-up who had an MMSE-1 score. This sample was stratified by MMSE-1 score to avoid oversampling of subjects with high MMSE-1 scores. A second MMSE score was obtained from 134 elderly, whereas 18 subjects refused participation and 14 subjects were not traceable. The median age at first assessment was 89 years (25th percentile 87, 75th percentile 92), the mean follow-up period (S.D.) was 3·3 (0·5) years. The median change in MMSE score was minus 4 points (95% confidence interval (CI) − 7 to − 2) and the slope of the regression line of MMSE-2 on MMSE-1 was 1·1 (95% CI 0·9–1·3). It is likely that the slope was underestimated due to a floor effect, regression to the mean and missing observations. However, the probability of decline decreased if MMSE-1 was higher. Nevertheless, the probability ranged from 27 to 59% for subjects with the highest MMSE-1 scores aged 85 and 95 years respectively. The latter is an argument in favour of a periodical examination of all subjects aged 85 and over to reveal causes of cognitive decline that can be treated or are amenable to prevention.


2009 ◽  
Vol 22 (1) ◽  
pp. 11-16 ◽  
Author(s):  
Andreas Kaiser ◽  
Renate Gusner-Pfeiffer ◽  
Hermann Griessenberger ◽  
Bernhard Iglseder

Im folgenden Artikel werden fünf verschiedene Versionen der Mini-Mental-State-Examination dargestellt, die alle auf der Grundlage des Originals von Folstein erstellt wurden, sich jedoch deutlich voneinander unterscheiden und zu unterschiedlichen Ergebnissen kommen, unabhängig davon, ob das Screening von erfahrenen Untersuchern durchgeführt wird oder nicht. Besonders auffällig ist, dass Frauen die Aufgaben «Wort rückwärts» hoch signifikant besser lösten als das «Reihenrechnen». An Hand von Beispielen werden Punkteunterschiede aufgezeigt.


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