scholarly journals Guidance for nuclear medicine staff on radiopharmaceuticals drug interaction

2009 ◽  
Vol 45 (4) ◽  
pp. 619-624
Author(s):  
Ralph Santos-Oliveira
Keyword(s):  
Systematic Review ◽  
Nuclear Medicine ◽  
Drug Interaction ◽  
Drug Interactions ◽  
Adverse Reactions ◽  
Logical Framework ◽  
Review Of Literature ◽  
Review Of The Literature ◽  
The World ◽  
Almost All

Numerous drug interactions related to radiopharmaceuticals take place every day in hospitals many of which are not reported or detected. Information concerning this kind of reaction is not abundant, and nuclear medicine staff are usually overwhelmed by this information. To better understand this type of reaction, and to help nuclear medicine staff deal with it, a review of the literature was conducted. The results show that almost all of radiopharmaceuticals marketed around the world present drug interactions with a large variety of compounds. This suggests that a logical framework to make decisions based on reviews incorporating adverse reactions must be created. The review also showed that researchers undertaking a review of literature, or even a systematic review that incorporates drug interactions, must understand the rationale for the suggested methods and be able to implement them in their review. Additionally, a global effort should be made to report as many cases of drug interaction with radiopharmaceuticals as possible. With this, a complete picture of drug interactions with radiopharmaceuticals can be drawn.

Clinical characterization and treatment outcomes of intracerebral and subarachnoid hemorrhage after vaccination against COVID-19: A systematic review of the literature v1

2021 ◽  
Author(s):  
Jin Pyeong Jeon ◽  
Chung Liang Chai ◽  
Jong Kook Rhim ◽  
Jeong Jin Park ◽  
Yong Jun Cho ◽  
...  
Keyword(s):  
Systematic Review ◽  
Subarachnoid Hemorrhage ◽  
Intracerebral Hemorrhage ◽  
Treatment Outcomes ◽  
Cerebral Hemorrhage ◽  
Adverse Reactions ◽  
Clinical Course ◽  
Review Of The Literature ◽  
The World ◽  
Patient Prognosis

As the number of COVID-19 vaccines increases, reports of complications are also increasing. In particular, when cerebral hemorrhage occurs, the prognosis is poor. Here, we aimed to investigating the clinical course of patients who developed intracerebral hemorrhage after COVID-19 vaccination and the patient prognosis through a systematic review. As coronavirus disease 2019 (COVID-19) hit the world like never before, there were 244,105,621 infection cases and 4,959,347 deaths worldwide as of October 24, 2021. As the number of vaccination increases, reports of death and serious adverse reactions after vaccination are also increasing.

Inactivation of Sarcocystis bradyzoites in food; a review

2021 ◽  
Author(s):  
Hadi Valizadeh
Keyword(s):  
Systematic Review ◽  
Gamma Rays ◽  
Meat Industry ◽  
Review Of The Literature ◽  
Control Techniques ◽  
The World ◽  
Cardiac Muscles ◽  
Infected Meat ◽  
And Control ◽  
Internet Databases

The eradication of Sarcocystis-infected corpses costs the meat industry millions of dollars each year. Because this parasite is most commonly found in skeletal and cardiac muscles, preventative and control techniques such as inactivating or destroying the bradyzoites in infected meat are critical. The goal of this research was to look at the various methods for inactivating this parasite and to compare the results of these methods. Using internet databases from many fields and around the world, a systematic review of the literature was conducted. Heating, freezing, irradiation, and marination were all utilized to inactivate this parasite, and each had a distinct effect, according to the studies. Inactivation can be achieved by heating at 60°C for 20 min or freezing at -4ºC for 2 days. Also, 2 kGy of gamma rays and marination in 6% NaCl and 3% acetic acid for 48 h are enough.

Drug–drug interactions

ESC CardioMed ◽  
2018 ◽  
pp. 226-233
Author(s):  
Jeffrey K. Aronson
Keyword(s):  
Drug Interaction ◽  
Protein Binding ◽  
Drug Interactions ◽  
Adverse Reactions ◽  
Mechanisms Of Action ◽  
Intravenous Drug ◽  
Cellular Distribution ◽  
Drug Infusion ◽  
Pharmacodynamic Interactions ◽  
Site Of Action

A drug interaction occurs when the effects of a drug are altered by the effects of another drug, a vaccine, herb, foodstuff, or device. In drug–drug interactions, a precipitant drug increases or reduces the effects of an object drug by pharmaceutical, pharmacokinetic, or pharmacodynamic mechanisms. Pharmaceutical interactions occur during intravenous drug infusion; they are avoidable by infusing drugs separately. Pharmacokinetic interactions can arise from altered absorption, protein binding, cellular distribution, metabolism, or excretion of an object drug. The last two mechanisms are the most important. Pharmacodynamic interactions can be direct (antagonism or synergism at the same site of action, or summation or synergism of similar effects at different sites) or indirect (when an outcome of an action of a precipitant drug alters the effects of an object drug). Some drug–drug interactions are beneficial, through combining drugs with different beneficial mechanisms of action or using drugs to reverse or prevent adverse reactions.

scholarly journals MaioRegen Osteochondral Substitute for the Treatment of Knee Defects: A Systematic Review of the Literature

2019 ◽  
Vol 8 (6) ◽  
pp. 783 ◽  
Author(s):  
Riccardo D’Ambrosi ◽  
Federico Valli ◽  
Paola De Luca ◽  
Nicola Ursino ◽  
Federico Usuelli
Keyword(s):  
Systematic Review ◽  
Clinical Improvement ◽  
Three Dimensional ◽  
Lesion Size ◽  
Review Of The Literature ◽  
Level Of Evidence ◽  
Significant Clinical Improvement ◽  
Almost All ◽  
Femoral Condyles

Background: This study aims to investigate the clinical and radiological efficacy of three-dimensional acellular scaffolds (MaioRegen) in restoring osteochondral knee defects. Methods: MEDLINE, Scopus, CINAHL, Embase, and Cochrane Databases were searched for articles in which patients were treated with MaioRegen for osteochondral knee defects. Results: A total of 471 patients were included in the study (mean age 34.07 ± 5.28 years). The treatment involved 500 lesions divided as follows: 202 (40.4%) medial femoral condyles, 107 (21.4%) lateral femoral condyles, 28 (5.6%) tibial plateaus, 46 (9.2%) trochleas, 74 (14.8%) patellas, and 43 (8.6%) unspecified femoral condyles. Mean lesion size was 3.6 ± 0.85 cm2. Only four studies reported a follow-up longer than 24 months. Significant clinical improvement has been reported in almost all studies with further improvement up to 5 years after surgery. A total of 59 complications were reported of which 52 (11.1%) experienced minor complications and 7 (1.48%) major complications. A total of 16 (3.39%) failures were reported. Conclusion: This systematic review describes the current available evidence for the treatment of osteochondral knee defects with MaioRegen Osteochondral substitute reporting promising satisfactory and reliable results at mid-term follow-up. A low rate of complications and failure was reported, confirming the safety of this scaffold. Considering the low level of evidence of the study included in the review, this data does not support the superiority of the Maioregen in terms of clinical improvement at follow-up compared to conservative treatment or other cartilage techniques.

scholarly journals SERUM LEPTIN LEVENS AND HEPATOCELLULAR CARCINOMA: REVIEW ARTICLE

2016 ◽  
Vol 29 (4) ◽  
pp. 276-278 ◽  
Author(s):  
Luiza Vitelo ANDRIGHETTO ◽  
◽  
Aline Kirjner POZIOMYCK ◽  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Systematic Review ◽  
Adipose Tissue ◽  
Key Words ◽  
Malignant Tumors ◽  
Review Article ◽  
Review Of The Literature ◽  
Serum Leptin ◽  
The World ◽  
The Relationship

ABSTRACT Introduction: Hepatocellular carcinoma is one of the most frequent types of malignant tumors in the world. There is growing evidence of the relationship between it development and obesity. The mechanism that links obesity to cancer is still not fully understood; however, it is essential to the understanding the adipose tissue in metabolic changes related to obesity and hepatocellular carcinoma. Objective: To review the influence of serum leptin levels in patients with hepatocelular carcinoma. Method: Systematic review of the literature based on the methodology of the Cochrane Institute. The search for articles was in the database: Science Direct, Scielo, Medline, Lilacs e Pubmed. The key words used were hepatocellular carcinoma, leptin, adipokine. Results: After evaluation of individual studies, were selected seven studies. The results previously studied are still inconsistent and contradictory, and leptin can be effectively involved in the occurrence and development of hepatocellular carcinoma. Conclusion: Therefore, it is necessary to develop prospective, well-designed and conducted focusing on the role and specific mechanisms of this hormone in patients with hepatocellular carcinoma, so that new correlations can be properly supported.

scholarly journals Safety of Moxibustion: A Systematic Review of Case Reports

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Ji Xu ◽  
Hongyong Deng ◽  
Xueyong Shen
Keyword(s):  
Systematic Review ◽  
Basal Cell Carcinoma ◽  
Adverse Events ◽  
Medical Treatment ◽  
Cell Carcinoma ◽  
Premature Birth ◽  
Adverse Reactions ◽  
Case Reports ◽  
Fetal Distress ◽  
The World

Moxibustion is a traditional medical treatment originating in China. It involves using the heat of burning moxa to stimulate acupoints. It is considered safe and effective and is widely used throughout the world. The increasing use of moxibustion has drawn attention to the procedure’s adverse events (AEs). This review covers a total of 64 cases of AEs associated with moxibustion in 24 articles, reported in six countries. Some evidence of the risks of moxibustion has been found in these cases. AEs include allergies, burns, infection, coughing, nausea, vomiting, fetal distress, premature birth, basal cell carcinoma (BCC), ectropion, hyperpigmentation, and even death. The position, duration, distance between moxa and skin, proficiency of the practitioners, conditions of the patients, presence of smoke, and even the environment of treatment can affect the safety of moxibustion. Improving practitioner skill and regulating operations may reduce the incidence of adverse reactions and improve the security of moxibustion.

scholarly journals Does aid support democracy? A systematic review of the literature

2021 ◽  
Author(s):  
Rachel M. Gisselquist ◽  
Miguel Niño-Zarazúa ◽  
Melissa Samarin
Keyword(s):  
Systematic Review ◽  
Foreign Aid ◽  
Positive Impact ◽  
Analytical Framework ◽  
Aid Effectiveness ◽  
Review Of The Literature ◽  
Agent Based ◽  
The World ◽  
Democracy Building ◽  
Structural Theories

This study draws on a rigorous systematic review—to our knowledge the first in this area—to take stock of the literature on aid and democracy. It asks: Does aid—especially democracy aid—have positive impact on democracy? How? What factors most influence its impact? In so doing, it considers studies that explicitly focus on ‘democracy aid’ as an aggregate category, its subcomponents (e.g. aid to elections), and ‘developmental aid’. Overall, the evidence suggests that i) democracy aid generally supports rather than hinders democracy building around the world; ii) aid modalities influence the effectiveness of democracy aid; and iii) democracy aid is more associated with positive impact on democracy than developmental aid, probably because it targets key institutions and agents of democratic change. The review presents a new analytical framework for considering the evidence, bringing together core theories of democratization with work on foreign aid effectiveness. Overall, the evidence is most consistent with institutional and agent-based theories of exogenous democratization, and least consistent with expectations drawn from structural theories that would imply stronger positive impact for developmental aid on democratization.

scholarly journals Analysis of mobile applications reporting on nutritional recipes: a review of the scientific literature

2021 ◽  
Vol 229 ◽  
pp. 01060
Author(s):  
Jose Huamaní-Cahuana ◽  
Michael Cabanillas-Carbonell
Keyword(s):  
Systematic Review ◽  
Social Isolation ◽  
Mobile Applications ◽  
World Economy ◽  
New Technologies ◽  
Scientific Literature ◽  
Review Of Literature ◽  
Nutritional Information ◽  
The World

At present the planet faces a pandemic originated by the COVID-19, causing social isolation and decrease in the world economy; limiting more and more the resources of many people, which produces a deficient feeding, In this document a systematic review of literature was made considering scientific articles between the years 2010 and 2020 from sources like, IEEE Xplore, Concytec, Proquest, Scopus, WoS and Scielo, having as objective to know the best characteristics of mobile applications to inform about nutritional recipes. A total of 50 articles were studied and it was concluded that there are databases with nutritional information of foods that help greatly in improving the nutrition of people, also found various techniques for obtaining data from new technologies.

scholarly journals Gastrointestinal perforation in COVID-19 patients – case series and review of the literature

2020 ◽  
Vol 4 (4) ◽  
pp. 18-21
Author(s):  
Deepak Verma ◽  
◽  
Sarthak Sharma ◽  
Lalit Kishore Garg ◽  
Aishwarya Tinaikar
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Gastric Perforation ◽  
Rare Complication ◽  
Case Series ◽  
Colonic Perforation ◽  
Gastrointestinal Perforation ◽  
Review Of The Literature ◽  
Abdominal Symptoms ◽  
The World ◽  
Almost All

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV 2) involving the respiratory tract started in 2019 in Wuhan, China but spread to almost all parts of the world to the extent that it was declared a pandemic by WHO. As more and more cases are detected, the involvement of systems other than respiratory was observed and nearly 5 to 50 % of patients have abdominal symptoms like pain and diarrhea. During the course of treatment, few patients developed a rare complication of gastrointestinal perforation. Three cases (two with colonic perforation and one with gastric perforation) of gastrointestinal perforation in COVID-19 positive patient are reported in the article with a review of the literature regarding the various hypothesis of intestinal perforation in these patients. Keywords: COVID-19; gastrointestinal perforation; severe acute respiratory syndrome coronavirus-2 (SARS-CoV 2); Tocilizumab

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