Effect of Staphylococcus aureus Cell-Wall Peptidoglycan on the Rat Myometrial Contractility Regulation by Adenylate Cyclase Signaling System

2017 ◽  
Vol 8 (1) ◽  
pp. 65-76
Author(s):  
Lilit S. Nasibyan ◽  
Igor B. Philyppov
Keyword(s):  
Staphylococcus Aureus ◽  
Cell Wall ◽  
Adenylate Cyclase ◽  
Signaling System ◽  
Cell Wall Peptidoglycan ◽  
Myometrial Contractility ◽  
Adenylate Cyclase Signaling System

Covalent Sortase A Inhibitor ML346 Prevents Staphylococcus aureus Infection of Galleria mellonella

2021 ◽  
Author(s):  
Xiang-Na Guan ◽  
Tao Zhang ◽  
Teng Yang ◽  
Ze Dong ◽  
Song Yang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cell Wall ◽  
Galleria Mellonella ◽  
Surface Proteins ◽  
Sortase A ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Aureus Infection ◽  
Cell Wall Peptidoglycan

The housekeeping sortase A (SrtA), a membrane-associated cysteine transpeptidase, is responsible for anchoring surface proteins to the cell wall peptidoglycan in Gram-positive bacteria. This process is essential for the regulation...

scholarly journals Author Correction: Structural basis of cell wall peptidoglycan amidation by the GatD/MurT complex of Staphylococcus aureus

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Erik R. Nöldeke ◽  
Lena M. Muckenfuss ◽  
Volker Niemann ◽  
Anna Müller ◽  
Elena Störk ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cell Wall ◽  
Structural Basis ◽  
Cell Wall Peptidoglycan

Influence of Carbohydrate Residues on Antibacterial Activity of Vancomycin

2020 ◽  
Vol 17 (4) ◽  
pp. 287-293
Author(s):  
Justyna Samaszko-Fiertek ◽  
Monika Szulc ◽  
Barbara Dmochowska ◽  
Maciej Jaśkiewicz ◽  
Wojciech Kamysz ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cell Wall ◽  
Antibacterial Activity ◽  
Bacterial Cell ◽  
Bacterial Cell Wall ◽  
Reductive Alkylation ◽  
Cell Wall Peptidoglycan ◽  
Mechanism Of Interaction ◽  
Reference Strains

This paper presents synthesis of vancomycin derivatives modified with selected 1- and 2-aminoalditols to carboxylic function and 2,5-anhydro-D-mannose and D-talose to amino function of vancosamine via reductive alkylation. MIC and MBC of these derivatives were determined for reference strains of bacteria: Staphylococcus aureus ATCC 25923, ATCC 6538, ATCC 6538/P, S. epidemidis ATCC 14490, E. faecium PCM 1859, E. faecalis PCM 2673, S. pyogenes PCM 465, and S. pneumonia ATCC 49619 and compared with the activity of vancomycin and its aglycone. Our findings confirm that sugar fragments can play an important role in the mechanism of interaction of vancomycin with bacterial cell wall peptidoglycan.

scholarly journals Structural basis of cell wall peptidoglycan amidation by the GatD/MurT complex of Staphylococcus aureus

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Erik R. Nöldeke ◽  
Lena M. Muckenfuss ◽  
Volker Niemann ◽  
Anna Müller ◽  
Elena Störk ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cell Wall ◽  
Structural Basis ◽  
Cell Wall Peptidoglycan
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