scholarly journals Dermatophytosis caused by Trichophyton mentagrophytes var. erinacei in a dog: a case report

2014 ◽  
Vol 59 (No. 7) ◽  
pp. 349-351 ◽  
Author(s):  
A. Kurtdede ◽  
AE Haydardedeoglu ◽  
H. Alihosseini ◽  
EC Colakoglu
Keyword(s):  
Trichophyton Mentagrophytes ◽  
Skin Lesions ◽  
Fungal Culture ◽  
Indirect Contact ◽  
Blood Smears ◽  
Fungicidal Treatment ◽  
Mongrel Dog ◽  
History Of ◽  
Oral Itraconazole ◽  
Peripheral Blood Smears

Trichophyton mentagrophytes var. erinacei is rarely isolated from dogs with dermatophytosis. It is a zoophilic dermatophyte transmitted by hedgehogs and, in contrast to other dermatophyte species, is characterised by a severe suppurative and inflammatory response known as kerion. A 5-year-old male mongrel dog was referred to the Veterinary Teaching Hospital with a 2-week history of a localised pruritic and suppurative alopecic lesion on the scrotum. Routine blood tests, peripheral blood smears, multiple skin scrapings and bacteriological culture did not reveal any abnormalities. However, Trichophyton mentagrophytes var. erinacei was isolated from a fungal culture. The presence of hedgehogs around the daily walking areas of the dog suggested the possibility of direct or indirect contact of the dog with hedgehogs. Fungicidal treatment was implemented with oral itraconazole (5 mg/kg once daily) and topical application of clotrimazole (twice daily) for a month. The scrotal lesion healed completely and hair grew back within a month. No recurrence occurred during a 4 month follow-up. T. mentagrophytes var. erinacei should be included in the differential diagnosis of suppurative scrotal skin lesions of dogs, which have come into possible contact with hedgehogs.

scholarly journals A Case of Cutaneous Purpureocillium lilacinum Infection Looking like Psoriasis

2021 ◽  
pp. 72-76
Author(s):  
Nam Gyoung Ha ◽  
Kyung Duck Park ◽  
Yong Jun Bang ◽  
Jae Bok Jun ◽  
Jong Soo Choi ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Its Region ◽  
Skin Lesions ◽  
Blue Staining ◽  
Rrna Gene ◽  
Fungal Culture ◽  
Environmental Distribution ◽  
Purpureocillium Lilacinum ◽  
Light Yellow ◽  
Oral Itraconazole

Purpureocillium lilacinum is a saprophytic fungus with a ubiquitous environmental distribution, and it can be detected in soil samples and decaying materials worldwide. It has been reported as an emerging pathogen in both immunocompromised and immunocompetent patients, showing various cutaneous presentations. Herein, we report a case of a patient with a localized cutaneous P. lilacinum infection, which resembles the skin lesions of psoriasis. A 72-year-old female was presented with a peripherally spreading, well-demarcated, asymptomatic, scaly, erythematous patch on her forehead for several months. Histopathological examination showed pinkish septated fungal elements and mixed inflammatory and granulomatous infiltrates in the dermis. Furthermore, a fungal culture on potato dextrose agar showed gray, velvety colonies with light yellow background after being subcultured. Phialides with chains of oval conidia were observed on lactophenol cotton blue staining. The ITS region of rRNA gene sequence obtained from the colony was identical to that of Purpureocillium lilacinum. The lesion was resolved with oral itraconazole (200 mg/day) after four months of treatment.

scholarly journals Flow Cytometric, Morphologic, and Laboratory Comparative Study in Patients With Leukocytosis and Cytopenia

2019 ◽  
Vol 153 (2) ◽  
pp. 266-273
Author(s):  
Estafani Rivas ◽  
Fred V Plapp ◽  
Wei Cui
Keyword(s):  
Flow Cytometry ◽  
Peripheral Blood ◽  
Screening Test ◽  
Hematologic Malignancy ◽  
Cost Effective ◽  
Effective Screening ◽  
Flow Cytometric ◽  
Blood Smears ◽  
History Of ◽  
Peripheral Blood Smears

Abstract Objectives We wanted to evaluate the effectiveness of flow cytometry immunophenotyping (FCI) as a screening test for patients with leukocytosis and cytopenia. Methods We identified 320 patients during August 2016 to December 2016 and evaluated FCI and morphology of peripheral blood smears (PBSs). Results The most common indications for FCI included history of hematologic malignancy (HHM, n = 126), leukocytosis (n = 80), and cytopenia (n = 53). Positive FCI rate was low with a range of 4.4% to 12.5% in patients with absolute neutrophilia regardless of HHM, if cases with circulating blasts were excluded. Patients with absolute lymphocytosis had a 93% positive FCI rate. Patients with HHM and pancytopenia showed a higher incidence of positive FCI findings than patients without HHM and with isolated cytopenia. PBS morphology correlated strongly with FCI (P = .0001). Conclusion PBS evaluation is an accurate and cost-effective screening test. FCI for patients with mature neutrophilia and isolated cytopenia has a very low yield.

scholarly journals Detection and Control of Dermatophytosis in Wild European Hedgehogs (Erinaceus europaeus) Admitted to a French Wildlife Rehabilitation Centre

2021 ◽  
Vol 7 (2) ◽  
pp. 74
Author(s):  
Cécile Le Barzic ◽  
Adela Cmokova ◽  
Chloé Denaes ◽  
Pascal Arné ◽  
Vit Hubka ◽  
...  
Keyword(s):  
Trichophyton Mentagrophytes ◽  
Skin Lesions ◽  
Fungal Culture ◽  
Prevention Measures ◽  
Rehabilitation Centre ◽  
Erinaceus Europaeus ◽  
Asymptomatic Carriers ◽  
Wildlife Rehabilitation ◽  
Trichophyton Erinacei ◽  
And Control

The rising number of European hedgehogs (Erinaceus europaeus) admitted every year to wildlife rehabilitation centres might be a source of concern to animal and public health since transmissible diseases, such as dermatophytosis, can be easily disseminated. This study seeks to evaluate the frequency of dermatophyte detection in hedgehogs admitted to a wildlife rehabilitation centre located near Paris, France, and to assess the risk of contamination in the centre in order to adapt prevention measures. A longitudinal cohort study was performed on 412 hedgehogs hosted at the Wildlife Animal Hospital of the Veterinary College of Alfort from January to December 2016. Animals were sampled once a month for fungal culture. Dermatophyte colonies were obtained from 174 out of 686 skin samples (25.4%). Besides Trichophyton erinacei, Trichophyton mentagrophytes and Nannizzia gypsea were also found. Dermatophyte detection seemed to be associated with the presence of skin lesions, while more than one-third of T. erinacei-positive animals were asymptomatic carriers. Healing required several months of treatment with topical and systemic azoles, but dermatophytosis did not seem to reduce the probability of release. Daily disinfection procedures and early detection and treatment of infected and asymptomatic carriers succeeded in limiting dermatophyte transmission between hedgehogs and humans.

scholarly journals Pulmonary fungal ball due to Trichophyton successfully managed with oral itraconazole: a case report

2021 ◽  
Vol 49 (12) ◽  
pp. 030006052110662
Author(s):  
Hsu-Lin Lee ◽  
Li-Mien Chen ◽  
Chen-Chu Chang ◽  
Guan-Liang Chen
Keyword(s):  
Fungal Infection ◽  
Left Lung ◽  
Lavage Fluid ◽  
Lung Field ◽  
Fungal Culture ◽  
Lung Lobe ◽  
Recommended Treatment ◽  
History Of ◽  
Oral Itraconazole

Pulmonary fungal balls are caused by long-term fungal infection of the lung. They are sometimes a complication of previous cavitary pulmonary tuberculosis. Pulmonary fungal balls caused by Trichophyton are extremely rare. A 65-year-old man who worked in a leather recycling factory was admitted because of a productive cough and shortness of breath. He had a history of tuberculosis with lung destruction. A chest radiograph showed an opacity surrounding an air lucency over the left lung field, and chest computed tomography showed a mass within a cavity, producing a ball-in-hole appearance, over the left upper lung lobe. Bronchoalveolar lavage was performed, and fungal culture of the lavage fluid yielded Trichophyton. After 6 months of treatment with oral itraconazole, the patient’s general condition improved. This case emphasizes the importance of awareness of fungal infection within cavitary lesions of the lung and shows that Trichophyton may be the etiologic organism in such cases. Itraconazole is a recommended treatment of pulmonary fungal balls.

scholarly journals Lymphocutaneous Sporotrichosis in a Patient with Underlying Systemic Lupus Erythematosus

2019 ◽  
Vol 21 (1) ◽  
pp. 59-61
Author(s):  
Asrul Abdul Wahab ◽  
Chuan Hun Ding ◽  
Nurul Hafizah Mohd Yusoff
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Biopsy Specimen ◽  
Sporothrix Schenckii ◽  
Laboratory Diagnosis ◽  
Skin Lesions ◽  
Systemic Lupus ◽  
Skin Biopsy Specimen ◽  
History Of ◽  
Oral Itraconazole

Sporotrichosis is a globally prevalent subcutaneous mycosis commonly acquired through traumatic inoculation. A 66-year-old woman with underlying systemic lupus erythematosus (SLE) presented initially with a painful non-healing nodule on her right thumb. There was no history of traumatic contact with soil, plants or animals. She was started on an antibiotic but developed multiple nodules on her right forearm which appeared to spread proximally. Culture of her skin biopsy specimen yielded Sporothrix schenckii. The lesions were successfully treated with oral itraconazole. In conclusion, a history of traumatic inoculation need not always be present in SLE patients with sporotrichosis and obtaining a laboratory diagnosis is crucial for those presenting with nodular skin lesions that spread proximally J MEDICINE JAN 2020; 21 (1) : 59-61

scholarly journals Subdural haematoma in Plasmodium falciparum and Plasmodium vivax mixed infection presenting multiple clinical complications

2013 ◽  
Vol 62 (12) ◽  
pp. 1902-1904
Author(s):  
Punith B. Devaraju ◽  
Shashiraja Padukone ◽  
Shivakumar R. Veerabhadraiah ◽  
Vijayakumar S. Ramachandrappa ◽  
Narayan Panji ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Plasmodium Vivax ◽  
Mixed Infection ◽  
Subdural Haematoma ◽  
Complete Recovery ◽  
Clinical Complications ◽  
Blood Smears ◽  
Good Clinical Condition ◽  
History Of ◽  
Peripheral Blood Smears

A 40-year-old man was admitted to hospital with a 5 day history of fever, restlessness and altered sensorium. Peripheral blood smears showed a Plasmodium vivax and Plasmodium falciparum mixed infection as revealed by the presence of rings, schizonts and gametocyte forms of the parasites. The patient soon became unconscious due to subdural haematoma (SDH) associated with disseminated intravascular coagulation and thrombocytopenia. Immediate intervention with a right fronto-parieto temporal craniectomy, evacuation of the SDH and intravenous quinine administration resulted in the patient’s complete recovery within 8 days of admission, and he was discharged in good clinical condition.

scholarly journals Tinea Pedis Presenting as Asymmetric Purpuric Papules on the Sole of the Foot: A Case Report

2015 ◽  
Vol 7 (1) ◽  
pp. 36-38
Author(s):  
Jennifer Yan Fei Chen ◽  
Marianne J. Stroz ◽  
David N. Adam
Keyword(s):  
Case Report ◽  
Potassium Hydroxide ◽  
Tinea Pedis ◽  
Trichophyton Mentagrophytes ◽  
Fungal Culture ◽  
Unique Case ◽  
Slide Preparation ◽  
Fungal Hyphae ◽  
History Of ◽  
Sole Of The Foot

In this report we describe a unique case of tinea pedis. A 29-year-old man presented with a 3-day history of asymptomatic purpuric papules predominantly on his left foot. Potassium hydroxide preparation demonstrated fungal hyphae and culture yielded Trichophyton mentagrophytes. This patient presented unusually with purpuric papules, unlike the three commonly described types of tinea pedis. Given the morphology, positive potassium hydroxide slide preparation, T. mentagrophytes on fungal culture and clinical response to ketoconazole cream, we conclude that this represents a unique variant of tinea pedis. We recognize that even common dermatological diagnoses can have unique presentations, and it is important for clinicians to maintain a broad differential for new dermatologic cases.

A Rare Case of Spinal Leprosy Mimicking Spinal Tuberculosis

2019 ◽  
pp. 33
Author(s):  
K Thuraikumar ◽  
V Naveen ◽  
Mustaqim A ◽  
Arieff AA ◽  
K Shri ◽  
...  
Keyword(s):  
Back Pain ◽  
Soft Tissue ◽  
Histopathological Examination ◽  
Posterior Instrumentation ◽  
Spinal Tuberculosis ◽  
Previous History ◽  
Skin Lesions ◽  
Titanium Implants ◽  
Paravertebral Abscess ◽  
History Of

Introduction: Spinal tuberculosis is the most common manifestation of extrapulmonar y tuberculosis. A combination of leprosy and tuberculosis is a rare entity.Case report: A 44-year-old male patient working as a laborer presented to our hospital with complaints of severe back pain and swelling over the back, difficulty in walking, associated with constitutional symptoms. On admission, he was febrile and had leukocytosis. Initial spine X-ray showed end plate destruction and increase in soft tissue shadow at the level of T8-T9. CT spine revealed thoracic paravertebral collection extending from T7 to T9 levels, suggest ive of tuberculous spondylitis with cold abscess. Patient refused a transpedicular biopsy and was started on anti-tubercular therapy. Two weeks after commencement of treatment, he developed worsening back pain and weakness of the lower extremities. MRI spine showed a paravertebral abscess and posterior soft tissue edema involving level of T7 to T11. Patient underwent a posterior decompression, debridement and posterior instrumentation. He was discharged well, there was improvement of his lower limb power. Upon clinic review, he complained of multiple hyperpigmented, painless, nonpruritic skin lesions over the trunk and back. No previous history of eczema, psoriasis and Tinea corporis. Given the history of allergy, initial impression was hypersensitivity reaction towards the titanium implants, and he was started on anti-histamines. However, there was no improvements seen. Histopathological examination of skin lesions revealed presence of granuloma within the dermis layer, composed of epitheloid, histiocytes, lymphocytes and plasma cells. Wade-Fite stain for Mycobacterium leprae is positive. Slit skin smear shows multibacillary leprosy. Patient was started on multidrug therapy (rifampicin, clofazimine and dapsone) for 1 year. He has recovered well.International Journal of Human and Health Sciences Supplementary Issue: 2019 Page: 33

Brightfield and fluorescence in-channel staining of thin blood smears generated in a pumpless microfluidic

2021 ◽  
Author(s):  
Kokou S. Dogbevi ◽  
Paul Gordon ◽  
Kimberly L. Branan ◽  
Bryan Khai D. Ngo ◽  
Kevin B. Kiefer ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Blood Smears ◽  
Peripheral Blood Smears ◽  
Thin Blood Smears

Effective staining of peripheral blood smears which enhances the contrast of intracellular components and biomarkers is essential for the accurate characterization, diagnosis, and monitoring of various diseases such as malaria.

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