Effects of top rope climbing therapy on joint health in adult haemophilia patients with severe arthropathies

Abstract Background: Low impact physical activity is important for patients with haemophilic arthropathies, but is often considered boring with suboptimal adherence. There is therefore a need for physical activities that motivate patient engagement. Aims: To evaluate the benefits of top rope climbing, increasingly used in other musculoskeletal disorders, as an engaging sports discipline in haemophilia. Materials/Methods: Six adult arthropathic patients with haemophilia (PWH) completed 12 sessions of tailored top rope climbing training. Functional and clinical joint status, climbing skills, quality of life (QoL), annual bleed rate (ABR) and joint findings with musculoskeletal ultrasound/power doppler (MSKUS/PD) were assessed before and after climbing. Results: Haemophilia joint health scores, dorsiflexion in arthropathic joints and climbing skills all improved. ABRs were comparable before and during climbing, and QoL remained high. MSKUS evaluation demonstrated no detrimental effects on synovial and cartilage health, with a decrease of inflammatory PD signal in some joints. Conclusion: We conclude that top rope climbing therapy (known as “Haemophilia Vertical”) can improve joint health in PWH with arthropathies. Haemophilia Vertical therefore emerges as an innovative athletic concept to promote physical activity among PWH. Further study investigating the longer-term impact in a larger cohort is warranted.

Download Full-text

Physical activity, musculoskeletal disorders, sleep, depression, and quality of life before and after bariatric surgery

Turkish Journal of Physical Medicine and Rehabilitation ◽

10.5606/tftrd.2020.3694 ◽

2020 ◽

Vol 66 (3) ◽

pp. 281-290

Author(s):

Filiz Sivas

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Bariatric Surgery ◽

Musculoskeletal Disorders ◽

Before And After

Download Full-text

SP697PHYSICAL PERFORMANCE, PHYSICAL ACTIVITY AND QUALITY OF LIFE BEFORE AND AFTER KIDNEY TRANSPLANTATION

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfy104.sp697 ◽

2018 ◽

Vol 33 (suppl_1) ◽

pp. i581-i581

Author(s):

Ryota Matsuzawa ◽

Kazunari Yoshida ◽

Daisuke Ishii ◽

Fumino Noguchi ◽

Masae Ikeda ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Kidney Transplantation ◽

Before And After

Download Full-text

Physical Activity and Quality of Life of Obese Patients Before and After Bariatric Surgery

Acta Scientific Gastrointestinal Disorders ◽

10.31080/asgis.2019.02.0056 ◽

2019 ◽

Vol 2 (6) ◽

pp. 10-13

Author(s):

Bruno Leandro de Melo Barreto ◽

Raphael José Perrier Melo ◽

Jones Silva Lima ◽

Rodrigo Conrado de Lorena Medeiros ◽

Jani Cléria Pereira Bezerra

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Bariatric Surgery ◽

Obese Patients ◽

Before And After

Download Full-text

The Effect of Non-Supervised Physical Activity Before and After Breast Cancer Surgery on Quality of Life; Follow-Up Results From a Randomised Controlled Trial (Physsurg-b)

10.21203/rs.3.rs-172101/v1 ◽

2021 ◽

Author(s):

Jenny Eva Maria Heiman ◽

Aron Onerup ◽

David Bock ◽

Eva Haglind ◽

Roger Olofsson Bagge

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Physical Activity ◽

Adjuvant Chemotherapy ◽

Controlled Trial ◽

Breast Cancer Surgery ◽

Before And After ◽

Randomised Controlled

Abstract PurposeWe conducted a randomised controlled trial (PhysSURG-B) to assess the short- and long-term effects of a non-supervised physical activity intervention at the time of breast cancer surgery. Here we report a secondary outcome, quality of life (QoL).MethodsFemale patients planned for surgery were randomly assigned to either an intervention of 30 minutes of self-administered physical aerobic activity daily 2 weeks before and 4 weeks after surgery, or control. QoL was assessed with questionnaires at baseline, 4 weeks and 12 months postop using the instruments FACT-B, RAND-36 and EQ-VAS.ResultsOut of 354 included participants at 12 months follow-up after surgery, 287 were available for QoL analysis. Comparing intervention to control, the results for the FACT- B score at 4 weeks showed an odds ratio (OR) of 0.975 (95% CI 0.636-1.495) and at 12 months an OR of 0.883 (95% CI 0.581-1.342). The subgroup of patients receiving adjuvant chemotherapy had significantly lower FACT-B at 12 months compared to no chemotherapy (OR 0.475, 95% CI 0.300-0.735). EQ-VAS showed OR 1.163 (95% CI 0.760-1.779) and 0.817 (95% CI 0.536-1.244) at 4 weeks and 12 months, respectively. RAND-36 domains “role limitations due to physical health” and “pain” showed a decrease at 4 weeks in both groups, returning towards baseline at 12 months follow-up.ConclusionAn intervention of non-supervised physical activity before and after surgery for breast cancer had no effect on QoL. Patients receiving adjuvant chemotherapy had significantly lower QoL, regardless of study group.Trial registrationClinicalTrials.gov registration number: NCT 02560662. Registered 25 September, 2015.

Download Full-text

THE IMPORTANCE OF PHYSICAL ACTIVITY IN DETERMINING THE QUALITY OF LIFE OF PEOPLE WITH MENTAL DEFICIENCY

Series IX: Sciences of Human Kinetics ◽

10.31926/but.shk.2020.13.62.2.21 ◽

2020 ◽

Vol 13(62) (2) ◽

pp. 163-172

Author(s):

S. BUHAȘ ◽

P.F. DRAGOȘ ◽

P. SZABO-ALEXI

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Health Status ◽

Mental Deficiency ◽

Physical Activities ◽

Health State ◽

Public And Private ◽

Public And Private Stakeholders ◽

Theoretical Insight

The present paper offers a theoretical insight regarding the quality of life and health state of people with mental deficiency. Research results regarding the link between physical activity and quality of life of people with mental disorders are discussed. Literature review outlined that physical activity generates major benefits for people with mental deficiency. Conclusions point out the need to implement physical activities that can be performed by people with mental deficiency to increase their quality of life. Public and private stakeholders should cooperate in order to develop specific strategies and policies, as well as adapted programs for people with mental deficiency to maintain their health status and quality of life at a decent level.

Download Full-text

Climbing therapy under PK-tailored prophylaxis

Hämostaseologie ◽

10.5482/hamo-14-01-0003 ◽

2014 ◽

Vol 34 (S 01) ◽

pp. S13-S16 ◽

Cited By ~ 7

Author(s):

E. Schmit ◽

D. Czepa ◽

K. Kurnik ◽

M. Spannagl ◽

M. Stemberger

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Half Life ◽

Bleeding Event ◽

Frequency Factor ◽

Severe Haemophilia ◽

Factor Activity ◽

Physical And Mental Health ◽

Joint Health

SummaryClimbing has a low risk of injury and strengthens the entire musculature. Due to its benefits in physical and mental health as well as its high fun factor climbing is an established way of therapy. So far, the usefulness of climbing therapy has not been shown for people with haemophilia (PWH). A crucial requirement for physical activity in PWH is regular prophylaxis. As the patient’s individual pharmacokinetic (PK) response varies significantly, PK-tailored prophylaxis may decrease bleeding frequency. Case report: We describe a man (age 25 years) with severe haemophilia A who took part in an 8.5-month weekly climbing program under PK-tailored prophylaxis. Bleeding frequency, factor consumption, joint health (Haemophilia Joint Health Score, HJHS), quality of life (Haemo-QoL-A) and climbing performance (UIAA scale) were assessed before and after the training. Prior to the study, the patient was on demand treatment. The patient was started on standard prophylaxis for a 2 months period and then observed for 6.5 months under PK-tailored prophylaxis. PK-tailored prophylaxis was targeted to a trough level of 1–3%. For high-impact activities a factor activity >15%, for low-impact activities a factor activity >5% was suggested. Results: Climbing therapy was safe. The bleeding rate decreased from 14 (2012) to 1 (during the study period of 8.5 months). The one bleeding event was due to a missed infusion and was not triggered by physical activity. The elimination half-life using Bayesian statistics was determined to be 16h. Using this half-life for PK-tailored prophylaxis reduced the factor VIII consumption in comparison to standard prophylaxis. Joint health was particularly improved in the categories range of motion and swelling. Quality of life scores stayed at a high level. Climbing performance improved by 1 grade. Conclusio: The combination of PK-tailored prophylaxis with therapeutic climbing improved clinical outcome in this young adult with severe haemophilia. The tailored concept for high- and low-impact activities appeared to be safe.

Download Full-text

Effect of a mobile pedometer-based walking challenge on quality of life amongst university employees: before and after study (Preprint)

10.2196/preprints.22671 ◽

2020 ◽

Author(s):

Arwa Alumran

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Public And Private ◽

University Employees ◽

Significant Difference ◽

Other Information ◽

Before And After ◽

Related Quality ◽

Health Related

BACKGROUND Regular physical activity has a direct association with an improvement in perceived health-related quality of life (HRQL). Because many Saudis are reportedly inactive, Imam Abdulrahman bin Faisal University established a walking challenge for all university employees to encourage a better lifestyle and to promote health awareness. OBJECTIVE This study aims to measure the differences in the participants’ HRQL scores before and after the challenge. METHODS a HRQL survey is sent to all university employees before the implementation of a pedometer-based walking challenge at the study setting. The questionnaire is re-sent after the challenge ended and differences in the overall HRQL were calculated. A RAND SF20-items scale was used to measure the participants’ HRQL scores, along with other information such as academic qualifications. RESULTS Most of the participants were between 31 and 50 years old, and 40% were males. There was a statistically significant difference in the overall HRQL scores before and after the walking challenge intervention. The HRQL score increased from 50.77 before the challenge to 55.53 after the challenge (paired t-test = -4.322, P < .0001). An odds ratio (OR) showed that the odds of having higher HRQL scores increased by 88% after the walking challenge, compared to before the walking challenge (OR = 1.88; 95% CI= 1.269-2.809; P = .002). CONCLUSIONS Physical activity by itself can improve a community’s overall health and quality of life. Similar interventions are encouraged in all public and private sectors in the country. CLINICALTRIAL NA

Download Full-text

Changes in kinesiostabilogram parameters and movement speed of stroke patients while increasing their physical activity due to the use of biofeedback method

European Journal of Translational Myology ◽

10.4081/ejtm.2021.9360 ◽

2021 ◽

Author(s):

Victoria Zaborova ◽

Anatoly Fesyun ◽

Konstantin Gurevich ◽

Alevtina Oranskaya ◽

Alexey Rylsky ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Depression Scale ◽

Movement Speed ◽

Stroke Survivors ◽

Before And After ◽

Web Camera ◽

The Stability ◽

Complications Of Stroke

Balance disorders are complications of stroke survivors. Aim of this study was the establish effectiveness of the biofeedback approach. In this intervention study 245 patients with early diagnosis of acute disturbance of cerebral circulation (ADCC) were examined. Patients able to move independently were treated by standard conservative ADCC therapy on an outpatient approach, but they continued to have problems with coordination of movement in upright position. Then they were submitted to an increasing physical activity based on five sessions of biofeedback, i.e., a complex rehabilitation of patients with motor pathology "Trust-M" according to TU 9442-001-63704475-2010. Mobility rates were assessed using a web camera. Patients' quality of life was evaluated by SF-36 questionnaire and the Hospital Anxiety and Depression Scale (HADS). All parameters were recorded before and after 5 sessions of biofeedback. After treatment, the stability indicators improved and all patients showed a significant increase in motion rate and quality of life. At the same time, the severity of pain and of depression and anxiety decreased. Negative correlations of average strength between the quadrant and patient HADS scaling rates were obtained. In conclusion, our work shows effectiveness of the biofeedback technique for correcting coordination in stroke survivors.

Download Full-text

Serum Concentrations of Vitamin D, Calcium, Phosphorus and Trace Minerals in Adults and Children with Haemophilia A: Association with Disease Severity, Quality of Life, Joint Health and Functional Status

International Journal of Hematology-Oncology and Stem Cell Research ◽

10.18502/ijhoscr.v14i1.2361 ◽

2020 ◽

Author(s):

Amir Abbasnezhad ◽

Mehdi Habibi ◽

Babak Abdolkarimi ◽

Soodabeh Zare ◽

Ezatollah Fazeli Moghadam ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Vitamin D ◽

Serum Levels ◽

Haemophilia A ◽

Serum Concentrations ◽

Joint Health ◽

Adults And Children ◽

Lower Physical Activity

Background: To investigate the serum levels of 25(OH)D and minerals in adults and children with haemophilia A, and the possible association of these factors with Pediatric Haemophilia/Haemophilia Activities List (PedHAL/HAL), Haemophilia Joint Health Score (HJHS) and Haemophilia-specific quality of life (QoL) index this case-control study was conducted. Materials and Methods: Eighty five haemophilia A patients (HP) registered in Hemophilia Society of Lorestan province were recruited. Along with HP, sex and age matched healthy controls (HCs) were recruited. Linear regression was used to evaluate the possible relation between biochemical factors and other variables. One-way analysis of variance (ANOVA) was used to compare the biochemical factors between three or more independent groups. Results: Results indicated that serum zinc, phosphorus and magnesium were significantly lower, whereas, serum level of alkaline phosphatase (ALP) was statistically higher in HP compared with HCs. Other biochemical factors including calcium and parathyroid hormone (PTH) were not different between groups. Serum 25(OH) D was lower only in children with haemophilia and not in adults. Percentage of subjects who were vitamin D deficient was higher in HP vs. HCs (57.6% vs. 35.3%), and also this rate was higher in children with haemophilia vs. adults (77.8% vs. 48.3%). Lower serum concentrations of assessed minerals and vitamin D were associated with lower physical activity, poor QoL and worst joint health, and these associations were stronger in children. Conclusion: Present study indicated that serum levels of vitamin D and minerals were low in HP, and these low levels were associated with poor QoL, lower physical activity and worst joint health.

Download Full-text