scholarly journals O USO DE ANTIINFLAMATÓRIOS ESTEROIDAIS E NÃO ESTERIODAIS NO CONTROLE DA DOR E DO EDEMA EM CIRURGIA DE TERCEIROS MOLARES

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Ricardo Natã Fonseca Silva ◽  
Lúcia Coelho Garcia Pereira
Keyword(s):  
Literature Review ◽  
Oral Cavity ◽  
Postoperative Period ◽  
Dental Arch ◽  
Third Molars ◽  
Drug Classes ◽  
Surgical Extraction ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Congenitally Missing

Introduction: Third molars are the last teeth to erupt through the oral cavity and in some cases they are congenitally missing, display impaction or remain included. There are many reasons for their removal: decay, lack of space in the dental arch or problems during its eruption. During surgical extraction, oral tissues may be injured, which causes painful symptoms and edema. To combat these surgical complications, it is necessary the use of drugs that fight inflammation, non-steroidal anti-inflammatory drug (NSAIDs) and corticosteroids. To obtain best results, the combination of NSAIDs and steroidal anti-inflammatory drugs are used in patients, either as preemptive medication and as postoperative medication. Objective: Performing a literature review in order to determine which drug classes have better postoperative outcomes for pain and swelling in of third molars extraction. Materials and methods: Studies present in SciELO, Lilacs and Pubmed databases published between 2000-2014 were included. Final considerations: Corticosteroids are used preemptively in order to reduce swelling frame, while NSAIDs have greater use in the postoperative period, in an attempt to reduce the pain.

scholarly journals Nonsteroidal Anti-Inflammatory Drugs and Opioids in Postsurgical Dental Pain

2020 ◽  
Vol 99 (7) ◽  
pp. 777-786 ◽  
Author(s):  
E.V. Hersh ◽  
P.A. Moore ◽  
T. Grosser ◽  
R.C. Polomano ◽  
J.T. Farrar ◽  
...  
Keyword(s):  
Naproxen Sodium ◽  
Analgesic Efficacy ◽  
Optimal Dose ◽  
Dental Pain ◽  
Third Molars ◽  
Short Course ◽  
Surgical Extraction ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Versus Risk

Postsurgical dental pain is mainly driven by inflammation, particularly through the generation of prostaglandins via the cyclooxygenase system. Thus, it is no surprise that numerous randomized placebo-controlled trials studying acute pain following the surgical extraction of impacted third molars have demonstrated the remarkable efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen sodium, etodolac, diclofenac, and ketorolac in this prototypic condition of acute inflammatory pain. Combining an optimal dose of an NSAID with an appropriate dose of acetaminophen appears to further enhance analgesic efficacy and potentially reduce the need for opioids. In addition to being on average inferior to NSAIDs as analgesics in postsurgical dental pain, opioids produce a higher incidence of side effects in dental outpatients, including dizziness, drowsiness, psychomotor impairment, nausea/vomiting, and constipation. Unused opioids are also subject to misuse and diversion, and they may cause addiction. Despite these risks, some dental surgical outpatients may benefit from a 1- or 2-d course of opioids added to their NSAID regimen. NSAID use may carry significant risks in certain patient populations, in which a short course of an acetaminophen/opioid combination may provide a more favorable benefit versus risk ratio than an NSAID regimen.

scholarly journals Agenesis of Bilateral Permanent Mandibular Canine: A Rare Case Report

2016 ◽  
Vol 04 (01) ◽  
pp. 056-058
Author(s):  
Deepti Jindal ◽  
Varun Jindal ◽  
Himanshu Singh ◽  
Swati Gautam ◽  
Ishita Bhojia ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Congenital Absence ◽  
Dental Arch ◽  
Review Of Literature ◽  
Third Molars ◽  
Comprehensive Review ◽  
Rare Case Report ◽  
Mandibular Canine ◽  
Congenitally Missing

AbstractHypodontia is the congenital absence of less than six teeth because of agenesis. Congenital absence of tooth (hypodontia) from the dental arch, may occur with any tooth, most commonly being third molars, however, absence of permanent mandibular canine is rare. The absence of teeth may be unilateral or bilateral. There are reports showing unilateral occurrence of permanent mandibular canines but agenesis of bilateral mandibular canines is not well documented in the literature and comprehensive review of literature shows paucity of data pertaining to this anomaly. Here we report one such rare case of congenitally missing mandibular permanent canines bilaterally.

scholarly journals The use of nonsteroidal anti - inflammatory drugs in polymorbid pathology

2020 ◽  
Vol 92 (1) ◽  
pp. 82-88
Author(s):  
N S Asfandiyarova ◽  
E V Philippov
Keyword(s):  
Risk Factors ◽  
Literature Review ◽  
Drug Selection ◽  
Prevention Measures ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

The literature review presents the possibilities of using non - steroidal anti - inflammatory drugs (NSAIDs) for polymorbid pathology. The mechanism of NSAIDs action, risk factors for the development of undesirable effects on the cardiovascular, digestive, urinary and other systems are considered; prevention measures and drug selection options are discussed, NSAIDs prescribing algorithm is considered.

scholarly journals USO DE ANALGÉSICOS Y ANTIINFLAMATORIOS EN UN SERVICIO DE CIRUGÍA BUCAL EN MEDELLÍN, 2013-2015

2019 ◽  
Vol 30 (2) ◽  
Author(s):  
Stefanía Hernández Viana ◽  
Natalia Silva Gómez ◽  
David Andrés Gálvis Pareja ◽  
María Cecilia Martínez Pabón
Keyword(s):  
Oral Surgery ◽  
Descriptive Study ◽  
Third Molars ◽  
Prescription Pattern ◽  
Drug Of Choice ◽  
Dental Practitioners ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
School Of Dentistry ◽  
Clinical Records

Introduction: dental surgical procedures trigger an inflammatory response, for which dental practitioners prescribe analgesic and anti-inflammatory medications using pharmacological guidelines that require knowledge on the use of medicines in a given environment. The aim of the present study was to identify the analgesics and anti-inflammatory drugs most commonly prescribed at the oral surgery service of the Universidad de Antioquia School of Dentistry. Methods: this retrospective descriptive study reviewed the clinical records of the oral surgery service in the period January 2013-August 2015. A total of 1,177 records were reviewed, and 709 were selected for analysis. Results: 53.1% of the drugs prescribed were non-selective Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Ibuprofen was formulated in 26.7% of all cases, followed by nimesulide with 24.1% and the combination of acetaminophen plus meloxicam with 10.2%. This same prescription pattern was observed in patients reporting no additional relevant medical history. In the case of gastric history, nimesulide was the drug of choice. 84% of all procedures were surgical extractions of third molars, with ibuprofen 600 mg postoperative for three days as the main therapeutic scheme. Conclusion: ibuprofen, nimesulide, and the combination acetaminophen plus meloxicam were the main analgesics and anti-inflammatory drugs prescribed in this study, according to medical and surgical records.

Anti-inflammatory drugs in the prevention of post-operative atrial fibrillation: a literature review

2019 ◽  
Vol 28 (1) ◽  
pp. 111-129
Author(s):  
Homa Nomani ◽  
Amir Hooshang Mohammadpour ◽  
Seyed Mohammad Hassan Moallem ◽  
Amirhossein Sahebkar
Keyword(s):  
Atrial Fibrillation ◽  
Literature Review ◽  
Post Operative Atrial Fibrillation ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Local application of combined natural essential oils for pain relief after elective throat surgery in the early postoperative period

2021 ◽  
Vol 20 (4) ◽  
pp. 96-101
Author(s):  
M. Ronis ◽  
◽  
D. Katovich ◽  
G. Sumeraga ◽  
◽  
...  
Keyword(s):  
Pain Relief ◽  
Essential Oils ◽  
Postoperative Period ◽  
Study Drug ◽  
Early Postoperative Period ◽  
Upper Respiratory Tract ◽  
Inflammatory Drugs ◽  
Upper Respiratory ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Tonsillectomy, cryptolysis of the palatine tonsils, and removal of various formations in the pharyngeal region are the most common elective operations in otorhinolaryngology. Pain in the early postoperative period is still the most frequent complication after these procedures, which can adversely affect the patient’s daily life. Considering the potential analgesic and anti-inflammatory effect of essential oil preparations, as well as their ability to be easily applied locally to the affected mucosal surface, it is worth considering their use to reduce pain and dysphagia in the postoperative period in the upper respiratory tract. The study involved 77 patients who were randomly divided into 2 groups: patients taking a drug containing combined natural essential oils (CNEO) and patients taking a placebo. In the course of the study, a questionnaire was used, according to which patients were interviewed immediately after the operation, then on the 3rd and 10th postoperative days. The results of the study show that the drug does not directly reduce postoperative pain in the pharynx, but in patients in the group with the drug based on combined essential oils, the frequency of taking non-steroidal anti-inflammatory drugs (NSAIDs) was less than in patients in the placebo group, which indirectly proves the effectiveness of the drug based on combined essential oils. Given the fact that the frequency of NSAID use is lower in the CPNEM group, it can be assumed that the study drug reduces the risk of side effects caused by NSAID use, and can also be an alternative method of pain relief for patients who are contraindicated in NSAIDs.

scholarly journals Foetal ductus arteriosus constriction unrelated to non-steroidal anti-Inflammatory drugs: a case report and literature review

2021 ◽  
Vol 53 (1) ◽  
pp. 860-873
Author(s):  
Giovanna Battistoni ◽  
Ramona Montironi ◽  
Jacopo Di Giuseppe ◽  
Luca Giannella ◽  
Giovanni Delli Carpini ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Ductus Arteriosus ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Negative predictive value of provocation tests for nonsteroidal anti-inflammatory drugs in children

2020 ◽  
Vol 41 (4) ◽  
pp. 285-289 ◽  
Author(s):  
Ozge Yilmaz Topal ◽  
Kulhas C. Ilknur ◽  
Yagmur T. Irem ◽  
Toyran Muge ◽  
Civelek Ersoy ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Provocation Test ◽  
Allergy Clinic ◽  
Predictive Values ◽  
Pediatric Allergy ◽  
Provocation Tests ◽  
Drug Classes ◽  
Drug Provocation Test ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Background: After antibiotics, nonsteroidal anti-inflammatory drugs (NSAID) are one of the leading drug classes responsible for hypersensitivity reactions in children. The drug provocation test (DPT) is the criterion standard for diagnosis. Objective: The aim of the present study was to determine the negative predictive values (NPV) of DPTs with NSAIDs in pediatric patients and to evaluate their attitudes toward NSAID use after a negative DPT result. Methods: The study included all patients who had undergone DPTs between January 1, 2014, and December 31, 2018, in our pediatric allergy clinic for suspected NSAID hypersensitivity reaction and who had a negative result for the suspected agent. Those patients who could be contacted were asked whether the patient had used the same drug again since the DPT and, if so, whether he or she had a reaction. Patients who were reported to have had a reaction were invited to the clinic for reevaluation. Based on the findings from this retesting, the NPVs of the DPTs with NSAIDs were calculated. Results: During the 5-year study period, DPT results were negative for 230 suspected agents in 215 patients. Of these, 143 patients (66.5%) were able to be contacted. A total of 108 patients (75.5%) had used the tested NSAIDs at least once after the provocation test, and five patients (4.6%) reported a reaction on reexposure. Four of these patients declined reevaluation, one patient exhibited no reaction in a second DPT. Therefore, the NPV was calculated as 96.3% (94.3% for ibuprofen, and 100% for paracetamol). Conclusion: The NPVs of DPTs with NSAIDs, especially of paracetamol DPT, is high in children. This finding should reassure the parents of patients who may require NSAID therapy again.

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