scholarly journals Clinical Scale for Neuropathic Pain

2021 ◽  
Vol 39 (2 Suppl) ◽  
pp. 24-36
Author(s):  
Eun Hee Sohn ◽  
Byoung Joon Kim

Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is underdiagnosed and difficult to treat. Questionnaires based on self-reported symptoms have improved diagnosis and management of neuropathic pain. Visual analog scale and numeric rating scale are most well-known unidimensional pain questionnaires. Multidimensional questionnaire or specialized questionnaire for neuropathic pain are more useful to diagnose neuropathic pain. Screening questionnaires help to identify neuropathic pain easily, and assessment questionnaires make it possible to create phenotypic profiles of neuropathic pain and determine an efficacy of management.

2020 ◽  
Author(s):  
Jofrid Kollltveit ◽  
Malin Osaland ◽  
Marianne Reimers ◽  
Magnus Berle

BackgroundPain is a subjective sensation; self-reporting is important for quantifying pain intensity. There are several different validated tools for this, such as Visual Analog Scale and Numeric Rating Scale. In the clinic, these terms are often used as equivalent. The objective of this study was to examine correlation and agreement between the pain registration tools in triage in an emergency department.Materials and MethodsThe study was performed in the Department of Emergency Medicine at Haukeland University Hospital in the period June-August 2019. We registered the pain score with two tools in 200 unselected patients in emergency admission with pain. In addition, we registrered gender, age, triage and general department affiliation.ResultsWe found a strong correlation between the pain registration tools by Spearmans correlation test (rho=0,930, p<0,001). There were no significant difference between the pain registration tools within the subgroups. Bland-Altman analysis show agreement between the two pain registration tools.ConclusionsIn an Emergency Department triage is it acceptable to use Visual Analog Scale and Numeric Rating Scale as equivalent, as long as the correct terminology is used.


2019 ◽  
Vol 37 (2) ◽  
pp. 135-143 ◽  
Author(s):  
Jingru Jiang ◽  
Yi Li ◽  
Qingyu Shen ◽  
Xiaoming Rong ◽  
Xiaolong Huang ◽  
...  

Purpose Neuropathic pain is an unavoidable treatment-related adverse event among patients with head and neck cancer who are undergoing radiotherapy. We aimed to test the efficacy and safety of pregabalin versus placebo in the treatment of radiotherapy-related neuropathic pain. Patients and Methods This randomized, double-blind, placebo-controlled trial was conducted in four centers in China. Eligible patients with a mean pain intensity score of 4 or more on an 11-point numeric rating scale were randomly assigned to receive either active treatment with a flexible dose of pregabalin or placebo for 16 weeks. The primary efficacy outcome was pain reduction measured on the numeric rating scale. Result There were 128 patients who received treatment as randomly assigned. Pain intensity reduction was 2.44 in the pregabalin arm and 1.58 in the placebo arm at week 16, yielding an adjusted mean difference of 0.87 (95% CI, 0.30 to 1.44; P = .003). In the pregabalin arm, 38 patients (59.4%) achieved at least 30% pain relief versus 21 (32.8%) in the placebo arm ( P = .006). Nineteen patients (29.7%) in the pregabalin group and five (7.8%) in the placebo group achieved 50% or greater pain relief ( P = .003). Total scores on the Profile of Mood States-Short Form, pain severity and functional interference of Brief Pain Inventory-Short Form, as well as the physiology and psychology domain of the WHO Quality of Life-BREF all were reduced significantly at week 16 in patients who received pregabalin compared with those who received placebo. There was no significant difference ( P = .29) in the incidence of experiencing at least one adverse event in the pregabalin arm (n = 35; 54.7%) versus the placebo arm (n = 29; 45.3%). Conclusion Patients treated with pregabalin with radiotherapy-related neuropathic pain had greater pain alleviation, better mood states, and higher quality of life compared with patients in the placebo group, with a good tolerability.


2019 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Claudia Elera-Fitzcarrald ◽  
Karen Vega ◽  
Rocío V. Gamboa-Cárdenas ◽  
Katiuska Zúñiga ◽  
Francisco Zevallos ◽  
...  

2020 ◽  
Author(s):  
Tomoko Tetsunaga ◽  
Tomonori Tetsunaga ◽  
Keiichiro Nishida ◽  
Haruo Misawa ◽  
Tomoyuki Takigawa ◽  
...  

Abstract Background: Mirogabalin, which is approved for the treatment of peripheral neuropathic pain in Japan, is a ligand for the α2δ subunit of voltage-gated calcium channels. Both pregabalin and mirogabalin act as nonselective ligands at the α2δ-1 and α2δ-2 subunits. Mirogabalin has a unique binding profile and long duration of action. Pregabalin has been reported to produce intolerable adverse effects in some patients. This study investigated outcomes associated with mirogabalin in patients with peripheral neuropathic pain who withdrew from treatment with pregabalin. Methods: We retrospectively assessed peripheral neuropathic pain in 187 patients (58 men, 129 women) who were treated with mirogabalin. All patients had been treated with pregabalin and withdrew from therapy due to lack of efficacy or adverse events. The mean age of patients was 72.3 years (range, 30–94 years), and mean duration of disease was 37 months (range, 3–252 months). Results: After treatment with mirogabalin for 1 week, numeric rating scale (NRS) scores decreased significantly compared with baseline, and continued to decrease over time . After 8 weeks, NRS scores improved by ³30% from baseline in 113 patients (69.3%). Twenty-four patients (12.8%) stopped mirogabalin treatment due to adverse events. Somnolence (26.7%), dizziness (12.3%), edema (5.9%), and weight gain (0.5%) were noted as adverse events of mirogabalin. Conclusions: The results of this investigation indicate that mirogabalin is safe and effective for reducing peripheral neuropathic pain.


2018 ◽  
Vol 2 (1) ◽  
pp. 10 ◽  
Author(s):  
Nadi Aprilyadi ◽  
H. Jhon Feri ◽  
Indah Dewi Ridawati

AbstrakDismenorea sering terjadi pada remaja. Di Indonesia prevalensi dismenore pada usia remaja sebesar 64,25% yang terdiri dari 54,89% dismenore primer dan 9,36% dismenore sekunder (Santoso, 2008). Secara farmakologi, penatalaksanaan adalah dengan pemberian obat-obat analgetik seperti golongan obat Nonsteroidal Antiinflammatory Drugs (NSAID) dapat meredakan nyeri. Salah satu pengobatan non farmakologi adalah dengan hipnoterapi yang merupakan aplikasi hipnosis dalam menyembuhkan masalah mental dan fisik (psikosomatis) seperti halnya nyeri, kecemasan, dll. Tujuan penelitian ini adalah untuk mengetahui pengaruh hipnoterapi terhadap nyeri dismenore pada siswi SMA PGRI I Lubuk Linggau. Penelitian ini merupakan penelitian pra eksperimen, dengan rancangan kuasi eksperimen one group pre and post test without control. Teknik sampel yang digunakan pada penelitian ini adalah Total Sampling sebanyak 17 responden. Instrumen yang digunakan dalam penelitian ini menggunakan quesioner penilaian nyeri Visual Analog Scale (VAS) dengan skala Numeric Rating Scale (NRS). Analisa univariat mayoritas siswi yang mengalami penurunan intensitas nyeri dismenore berusia 16- 17 tahun dan 100% responden mengalami penurunan intensitas nyeri dismenore setelah mendapatkan hipnoterapi, analisis bivariat dengan uji t-test didapatkan pengaruh yang signifikan Hipnoterapi terhadap penurunan intensitas nyeri dismenore (ƥ value 0,000). Hipnoterapi disarankan untuk digunakan dalam penerapan asuhan keperawatan nyeri khususnya guna mengurangi intensitas nyeri dismenore. Kata Kunci : Hipnoterapi, Dismenore Abstract The Effectiveness Of Hypnotherapy On Disease Of Diseases Of Dismenore In Female StudentSenior High School PGRI I Lubuklinggau.Dysmenorrhoea often occurs in adolescents. In Indonesia the prevalence of dysmenorrhea in adolescence is 64,25% consisting of 54,89% primary dysmenorrhea and 9,36% secondary dysmenorrhea (Santoso, 2008). Pharmacologically management is by administering analgesic drugs such as the Nonsteroidal Anti Inflammatory Drugs (NSAID) group to relieve pain. One of the non-pharmacological treatments is hypnotherapy which is the application of hypnosis in curing mental and physical problems (psychosomatic) as well as pain, anxiety, etc.The purpose of this study was to determine the effect of hypnotherapy on dysmenorrhea pain in high school students PGRI I LubukLinggau. This is a pre experimental study, with a quasi-experimental one group pre and post test without control design. The sample technique used in this study is Total Sampling of 17 respondents. The instrument used in this study used Visual Analog Scale (VAS) visual pain assessment quesioner with Numeric Rating Scale scale (NRS). Univariate analysis of the majority of students who experienced decreased intensity of dysmenorrhea pain aged 16-17 years and 100% of respondents experienced decreased intensity of dysmenorrhea pain after obtaining hypothotherapy, bivariate analysis with t-test test showed significant effect Hypnotherapy to decrease intensity of dysmenorrhea pain (ƥ value 0,000) .Hypnotherapy is recommended for use in the application of pain nursing care especially to reduce the intensity of dysmenorrhea pain. Keywords: Hypnotherapy, Dysmenorrhea


2015 ◽  
Vol 122 (2) ◽  
pp. 399-406 ◽  
Author(s):  
Pascal Vanelderen ◽  
Jan Van Zundert ◽  
Tamás Kozicz ◽  
Martine Puylaert ◽  
Pieter De Vooght ◽  
...  

Abstract Background: Less than 50% of patients experience sufficient pain relief with current drug therapy for neuropathic pain. Minocycline shows promising results in rodent models of neuropathic pain but was not studied in humans with regard to the treatment of neuropathic pain. Methods: In this randomized, double-blind, placebo-controlled clinical trial, patients with subacute lumbar radicular pain received placebo, amitriptyline 25 mg, or minocycline 100 mg once a day (n = 20 per group) for 14 days. Primary outcome measure was the pain intensity in the leg as measured by a numeric rating scale ranging from 0 to 10 on days 7 and 14. Secondary outcome measures were the reduction of neuropathic pain symptoms in the leg as determined with a neuropathic pain questionnaire, consumption of rescue medication, and adverse events on days 7 and 14. Results: Sixty patients were randomized and included in an intention-to-treat analysis. After 14 days, patients in the minocycline and amitriptyline groups reported a reduction of 1.47 (95% confidence interval, 0.16–2.83; P = 0.035) and 1.41 (95% confidence interval, 0.05–2.78; P = 0.043), respectively, in the numeric rating scale compared to the placebo group. No differences were seen in the neuropathic pain questionnaire values at any time point during treatment between the three groups. The rate of adverse events in the amitriptyline group was 10% versus none in the minocycline and placebo groups. No differences were noted in the consumption of rescue medication. Conclusions: Although both groups differed from placebo, their effect size was small and therefore not likely to be clinically meaningful.


2020 ◽  
Vol 7 (2) ◽  
pp. 264-269
Author(s):  
Iva Gamar Dian Pratiwi ◽  
Laylatul Hasanah

Dismenore atau nyeri haid yaitu ketidaknyamanan yang sering dialami remaja khususnya perempuan. Dismenore pada remaja terjadi 60% - 90% dan mengganggu aktivitas sehari hari. (Lestari H. Metusala, J.&Suryanto, 2010). Dari hasil penelitian, di Indonesia angka kejadian dismenore sebesar 64,25%, diantaranya 54,89% dismenore primer, 9,36% dismenore sekunder (Ningsih 2011). Wanita membutuhkan obat untuk mengurangi rasa nyeri baik dengan farmakologi maupun non farmakologi. Pengobatan yang di butuhkan wanita yaitu pengobatan yang tidak bersifat invasive dan yang cocok dengan pasien nyeri yang memerlukan penanganan holistik untuk mengintervensi psikis serta mencegah terjadinya konsumsi obat-obatan analgetik yang tidak rasional, pengobatan tersebut yaitu hipnoterapi.( Lucas N.N&Sugianto,2017). Penelitian ini bertujuan untuk menganalisa efektifitas spiritual hipnoterapi terhadap penurunan disminore. Jenis Penelitian  ini adalah penelitian kuantitatif pra experimental dengan pendekatan cross sectional. Rancangan penelitian yang digunakan adalah one group pretest posttest, jumlah sampel 30 responden. Tekhnik sampling yang digunakan purposive sampling yang sesuai kriteria inklusi. Penelitian ini dilakukan bulan April sampai Oktober 2019. Intrumen yang digunakan adalah kuesioner penilaian nyeri Visual Analog Scale (VAS) dengan skala Numeric Rating Scale (NRS). Hasil analisa data dengan Wilcoxon signed rank test didapatkan hasil p = 0,000<0,005 maka dapat disimpulkan bahwa spiritual hipnoterapi efektif dalam menurunkan nyeri dismenore pada mahasiswi Kebidanan. Dysmenorrhea or menstrual pain is discomfort that is often experienced by adolescents, especially women. Dysmenorrhea in adolescents occurs 60% - 90% and interferes with daily activities. (Lestari H. Metusala, J. & Suryanto, 2010). From the results of the study, in Indonesia the incidence of dysmenorrhea was 64.25%, including 54.89% of primary dysmenorrhea and 9.36% of secondary dysmenorrhea (Ningsih 2011). Women need drugs to reduce the pain, both with pharmacology and non-pharmacology, one of which is hypnotherapy. This study aims to analyze the spiritual effectiveness of hypnotherapy against decreasing dysminorrhea. This type of research is a pre-quantitative quantitative research with cross sectional approach. The research design used was one group pretest posttest, with a sample of 30 respondents. The sampling technique used is purposive sampling that matches the inclusion criteria. This research was conducted from April to October 2019. The instrument used was the Visual Analog Scale (VAS) pain assessment questionnaire with the Numeric Rating Scale (NRS). The results of data analysis with the Wilcoxon signed rank test showed p = 0,000 <0.005, so it can be concluded that there is a meaningful effectiveness of spiritual hypnotherapy for the reduction of dysmenorrhea pain in Midwifery students.


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