scholarly journals Comparison of survival outcome in early versus late surfactant therapy in preterm neonates with respiratory distress syndrome at a tertiary care centre: A randomized control trial (Open)

2017 ◽  
Vol 5 (7) ◽  
pp. 754-764
Author(s):  
Dr. Sharja Phuljhele ◽  
◽  
Dr. Santosh Kumar Rathia ◽  
Dr. Jitendra K Chukkanakal ◽  
◽  
...  
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Randomized Control Trial ◽  
Distress Syndrome ◽  
Tertiary Care ◽  
Survival Outcome ◽  
Preterm Neonates ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Randomized Control

scholarly journals Overview of Early Cases of Coronavirus Disease 2019 (COVID-19) at a Tertiary Care Centre in North India

2020 ◽  
Vol 49 (7) ◽  
pp. 449-455
Author(s):  
Shrikant Sharma ◽  
Prakash Keswani ◽  
Abhishek Bhargava ◽  
Ramji Sharma ◽  
Ajeet Shekhawat ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Interleukin 6 ◽  
Distress Syndrome ◽  
Tertiary Care ◽  
North India ◽  
Preventive Strategy ◽  
Care Centre ◽  
Tertiary Care Centre

Introduction: As the coronavirus disease 2019 (COVID-19) pandemic continues to spread on an unprecedented scale from around the world, we described our experience in treating early COVID-19 cases in India. Materials and Methods: An observational study of COVID-19 patients admitted to a tertiary care centre in North India between 2 March–4 April 2020 was performed. The clinical, epidemiological, laboratory, treatment and outcome data of patients were evaluated. Results: A total of 75 patients were treated and 56 (74.66%) were men. The clinical spectrum of COVID-19 ranged from asymptomatic to acute respiratory distress syndrome (ARDS). Fever (85.36%) was the most common symptom followed by cough (56.09%) and dyspnoea (19.51%). Findings from hemogram analysis showed that 32%, 21.33% and 18.67% of patients had lymphopaenia, eosinopenia and thrombocytopaenia, respectively. Inflammatory markers such as C-reactive protein, D-dimer, ferritin, fibrin degradation product and interleukin-6 were significantly elevated (P <0.05) in patients who required oxygen therapy than those who did not require it, suggesting the potential role such markers could play in predicting prognosis in patients. Mean hospital stay was 9.2 days and 72 (96%) patients made a complete recovery, but 3 (4%) patients demised after progressing to ARDS. Conclusion: The clinical and epidemiological spectrum of COVID-19 has jeopardised the health system in India. Without a proven therapy to combat this pandemic and with no sight of vaccines in the near future, a preventive strategy should be adopted to contain the spread of this infectious disease. Key words: Acute respiratory distress syndrome, Cytokine release syndrome, Interleukin-6, Lopinavir-ritonavir, Lymphopaenia

scholarly journals Morbidity profile of infants of mothers with gestational diabetes admitted to a tertiary care centre

2017 ◽  
Vol 4 (3) ◽  
pp. 960
Author(s):  
Devi Meenakshi K. ◽  
Narayana Babu R. ◽  
Srinivasan Padmanaban
Keyword(s):  
Gestational Diabetes ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Tertiary Care Centre ◽  
Insulin Group ◽  
Increased Risk ◽  
Meal Plan

Background: Infants born to mothers with gestational diabetes are at increased risk of neonatal morbidities like birth trauma, hyperbilirubinemia, hypoglycemia, birth asphyxia etc., Maternal glycemic control has been one of the parameters that determines the occurrence of these problems.Methods: A retrospective study done by analysing the case records of babies born to mothers with gestational diabetes and admitted to the NICU of Govt Kilpauk Medical college from January 2015 to December 2015. The morbidity profile of infants born to mothers with gestational diabetes was analysed and comparison was made between the two groups namely mothers who were managed by meal plan and those who were managed by insulin.Results: About 198 babies were analysed majority were delivered by caesarean section (83%). Only 2 babies (1%) weighed more than 4000gms. The commonest morbidity observed was hyperbilirubinemia (24.2%) which was 27.7% in the insulin group as against 19% in the group on meal plan. The next common morbidity was sepsis (15.2%). This was also common in insulin group 18.5% as against 10.1% in the meal group. Others were hypoglycemia (4%), congenital heart disease (2.5 %) and respiratory distress syndrome (1.5 %).Conclusions: Babies born to mothers with gestational diabetes were found to have morbidities like hyperbilirubinemia and sepsis. Less commonly found morbidities were hypoglycemia, birth asphyxia, respiratory distress syndrome etc., Though the morbidities were more common among insulin group as compared to the group on meal plan this difference was not statistically significant. 

scholarly journals Placental cord drainage during third stage of labour: a randomized control trial at a tertiary care centre

2020 ◽  
Vol 9 (3) ◽  
pp. 1143
Author(s):  
Megha Chaudhary ◽  
Maitri Shah ◽  
Nitin Makwana
Keyword(s):  
Blood Loss ◽  
Randomized Control Trial ◽  
Tertiary Care ◽  
Normal Vaginal Delivery ◽  
Control Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Third Stage ◽  
The Mean ◽  
Randomized Control

Background: Labour is a physiological process, but it is often associated with morbidity and mortality, with the most common cause being blood loss. Primary postpartum hemorrhage is commonly defined as a blood loss of 500 ml or more within 24 hours after normal vaginal birth. A prolonged third stage of labour (more than 20 min) is associated with postpartum hemorrhage. The present study was undertaken with the objective of assessing efficacy of placental cord drainage (PCD) during active management of third stage of labour.Methods: This is a randomized control trial in which full term primi gravida who were expected to have normal vaginal delivery, admitted in labour room of a tertiary care centre were evaluated for inclusion in the study. Total 126 participants were enrolled after having normal vaginal delivery. In study group (n = 63), placental cord drainage was used for management of third stage of labour while in control group (n = 63), third stage was managed without PCD.Results: The mean difference in duration of third stage of labour in study and control group was 1.79 minute and the mean difference in blood loss during third stage of labour in both groups was 57.86 ml which was statistically significant.Conclusions: The results of this study show small positive effects from cord drainage in reducing the length of the third stage of labour and in reducing the amount of blood loss when compared with those without cord drainage. The observed changes may be of clinical significance in reducing third stage related complications.

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