scholarly journals Trends of transfusion transmittable infections among voluntary blood donors in a cardiac care hospital, Bengaluru, India

2019 ◽  
Vol 7 (2) ◽  
pp. 139-142
Author(s):  
Dr. Sathyavathi Shivalingegowda ◽  
◽  
Dr. Krishnamurthy Banandur Nanjundappa ◽  
Dr. Umadevi Kannan ◽  
Dr. Manjunath Cholenahalli Nanjappa ◽  
...  
Keyword(s):  
Blood Donors ◽  
Cardiac Care ◽  
Care Hospital

SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Blood Bank ◽  
Care Hospital ◽  
Medical College ◽  
The World ◽  
First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

EVALUATION OF REASONS OF PRE-DONATION BLOOD DONOR DEFERRAL IN A TERTIARY CARE HOSPITALAT DHAKA

2021 ◽  
pp. 69-71
Author(s):  
Daanish Arefin Biswas ◽  
Tamanna Afroz ◽  
Md. Wasim ◽  
Bepasha Naznin ◽  
Hasiba Akter Bhuiyan
Keyword(s):  
Blood Donors ◽  
Tertiary Care ◽  
Standard Operating Procedure ◽  
Care Hospital ◽  
Male Population ◽  
Human Errors ◽  
Medical College ◽  
Safe Blood ◽  
Donor Deferral ◽  
Or History

Background: Our aim is to evaluate reasons of donor deferral in tertiary care hospital to nd new disease distribution, any areas of negligence in part of donor or history taking physicians and human errors which could be easily correctable and benecial for donors to remain healthy and provide safe blood. Methodology: This is a retrospective analytic study carried out during the period of January to December 2015 at Department of Transfusion Medicine, Sir Salimullah Medical College and Mitford Hospital. After preliminary registration, each donor was either selected or deferred by medical ofcers. The donor selection and deferral criteria were according to the standard operating procedure. Detailed information of reason of deferral was recorded. Results:Among 10056 registered donors, 9453 (94.004%) were eligible for donation and 603 (5.996%) blood donors were deferred due to various reasons. Male donors were 7526 (74.84%) more than female 2530 (25.16%). Females (60.03%) were found to have higher deferral rate than male population (39.97%). Low hemoglobin was found to be leading cause constituting 17.58% followed by hypertension 15.26%, medications 12.11% and underweight 11.28%. Conclusion: Deferral may discourage the donor for subsequent donations, especially young rst time donors. Deferred donors should be properly counseled and educated for probable future donations. By knowing the causes of deferral we can take further steps to prevent those causes and can preserve precious blood and blood components.

Increasing Seroprevalence of Hepatitis C Virus among Blood Donors - A 3 Year Study in North India

2021 ◽  
Vol 8 (07) ◽  
pp. 379-383
Author(s):  
Jagjeewan Ram ◽  
Namrata Nigam ◽  
Aparna Singh ◽  
Lubna Khan
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Blood Transfusion ◽  
Blood Donors ◽  
Tertiary Care ◽  
North India ◽  
Enzyme Linked Immunosorbent Assay ◽  
Care Hospital ◽  
Hepatitis C Infection ◽  
Case Volume

BACKGROUND The primary aspect of blood transfusion lies in the availability of blood and blood components which are tested and reported negative for transfusion transmitted infections (TTI’s). The increased seroprevalence of TTI’s indicate their prevalence in general public. The study was conducted to analyse the increasing seroprevalence of hepatitis C virus (HCV) over a period of 3 years. The objectives of the study determine the seroprevalence of hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV) among the voluntary blood donors at a tertiary care hospital & associated blood bank. METHODS This cross-sectional study was done at the Department of Transfusion Medicine, GSVM Medical College, Kanpur, Uttar Pradesh, over a period of 3 years from July 2017 to June 2020. The samples collected were screened by enzyme-linked immunosorbent assay (ELISA) tests. RESULTS A total of 69561 blood units were collected during this 3-year study from July 2017 to June 2020. Of all the blood bags screened, the highest prevalence was seen for HBV followed by HCV and HIV. 949 (1.4 %) were reactive for HBV, 75 (0.1 %) were reactive for HIV and 332 (0.5 %) were reactive for HCV. The results show a remarkable increase in the seropositivity for hepatitis C infection. CONCLUSIONS The seroprevalence of HCV has seen an increase in case load over the years as compared to HBV and HIV. This increase in case volume is indicative of impending liver diseases progressing to chronic stage over the years. Thus, it is imperative to create awareness in the general population to help reduce the risk factors responsible for HCV infection. KEYWORDS Blood Transfusion, Voluntary Donors, HCV, HBV, HIV, Seroprevalence, Transfusion Transmitted Infections (TTI’s)

Seroprevalence of transfusion transmitted infections among blood donors at a Tertiary Care Hospital Blood Bank in North India

2016 ◽  
Vol 9 (1) ◽  
pp. 77 ◽  
Author(s):  
DevRaj Arya ◽  
NL Mahawar ◽  
Rashi Pachaury ◽  
Arun Bharti ◽  
Lokesh Sharma ◽  
...  
Keyword(s):  
Blood Donors ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Blood Bank ◽  
North India ◽  
Care Hospital
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