SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Blood Bank ◽  
Care Hospital ◽  
Medical College ◽  
The World ◽  
First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

scholarly journals Seroprevalence of Hepatitis B and Hepatitis C Virus among Healthy Blood Donors in Tertiary Care Hospital

2018 ◽  
Vol 28 (1) ◽  
pp. 26-31
Author(s):  
SH Pramanik ◽  
Abu Shahin Mohammed Mahbubur Rahman ◽  
Md Nurul Islam ◽  
Md Golam Rabbani ◽  
Md Khalilur Rahman
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Post Transfusion Hepatitis

Hepatitis B virus (HBV) & Hepatitis C virus (HCV) are transfusion transmissible infections. A study was conducted from September, 2015 to March, 2016 at the Transfusion Medicine Department of Rajshahi Medical College Hospital to determine the prevalence of asymptomatic hepatitis B and C virus in apparently healthy blood donors, were subjected to ELISA for screening of hepatitis B surface antigen and Hepatitis C virus. A total of 200 blood donors were screened, the seroprevalence of HBV & HCV infection was 5.0% & 2.0% respectively. The HBV seroprevalence in male donors was 182/8 (4.4%) and in female donors was 18/2 (11.1%). Four donors were found seropositive for HCV giving a seroprevalence of 2%. HCV seroprevalence in male was 182/4 (2.2%) and no female. Seroprevalence of HCV and HBV were higher in younger donors, service holders, married respondents and middle class donors. To reduce the prevalence of post-transfusion hepatitis and stringent donor screening procedure, routine screening for HBV & HCV in blood banks should be performed using more sensitive methods (ELISA).TAJ 2015; 28(1): 26-31

SERO PREVALENCE OF TRANSFUSION TRANSMITTED INFECTIONS (TTI) IN VOLUNTARY BLOOD DONORS IN A TERTIARY CARE HOSPITAL AT SRINAGAR

2021 ◽  
Vol 5 (5) ◽  
Author(s):  
Nadia Shafi Chickan ◽  
Altaf Hussain Mir ◽  
Masaratt-ul Gani ◽  
Shazia Handoo ◽  
Farooq Ahmad Ganie
Keyword(s):  
Health Care ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Care Facility ◽  
Health Care Facility ◽  
Care Hospital ◽  
Serum Samples

Introduction: Blood transfusion plays an vital role in patients management and is live saving in my instances. it plays a pivotal role as a specialized modality of treatment and saves millions of lives worldwide each year and reduces morbidity. Stringent screening of blood not only ensure safe supply of blood and blood products, but also gives us idea about prevalence of ttis among general population Objective: to determine the serroperavalance of tti among blood donors in lalded hospital Materials and methods: A retrospective study was carried out over a period of 3 years from January 2017 to December 2019.serum samples were screened for hepatitis B surface antigen ,antibodies to human immunodeficiency virus Type 1 and 2 ,hepatitis c virus and syphilis in department of transfusion medicine was carried out Result: The result shows that 55 (3.72%) of the blood donors had TTIs. The prevalence of Hepatitis B, Hepatitis C, Malaria, Syphilis and Human immunodeficiency viruses (HIV), was found to be 31(0.21%), 23 (0.15%), 01 (0.0.006%), 01 (0.006%) and 02 (0.0.23%) respectively. None were positive for malaria. Conclusion: Transfusion Transmittable Infections pose a threat to patients admitted in any health care facility and if not carefully screened for will cause significant morbidity. Careful screening of all donor blood units in the blood bank of a hospital is absolutely necessary to prevent any untoward incidence of TTI in patients admitted to a health care facility Keywords: Transfusion, Sero-Prevalence, Donors, Transfusion Transmissible Infections.

scholarly journals Seroprevalence of human immunodeficiency virus, hepatitis B and hepatitis C among blood donors at a tertiary care hospital in North India

2020 ◽  
Vol 9 (11) ◽  
pp. 1671
Author(s):  
Kanwaljit Kaur ◽  
Ramneek Locham ◽  
Smriti Kaur Aulakh ◽  
Rajni Bassi ◽  
Jiteshwar Singh Pannu
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Blood Donors ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital ◽  
Donor Pool ◽  
Immunodeficiency Virus ◽  
First Time

Background: The prevalence of transfusion transmitted infections (TTIs), in blood transfusion services are a major problem across blood banks and hospitals in the world. In, India, the effort to provide safe transfusion to patients is a heightened problem for various reasons. In this study, seroprevalence of Transfusion transmitted infections such as human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) was investigated in a pool of blood donors.Methods: The data collection was carried out for a period of two years from, January 2017 to December 2018, and total sample size of donors was 38,142. We studied the frequency, gender wise distribution, donor (first time vs repeat) wise distribution and yearly trend of seroprevalence of TTIs in blood units donated at our hospital.Results: A total of 37,457 (98.2%) males and 685 (1.79%) females donated blood during the study period. The results suggest that among the blood donors, the prevalence of HCV was highest (0.77%) followed by HBV (0.46%) and HIV (0.13%). Seropositivity was found to be more in first-time donors (0.83%) as compared to repeat-donors (0.52%). Seropositivity was found to be more among males (1.35%) than females (0.01%). The discussion suggests underlying reasons for the results along-with future direction of research.Conclusions: The need of the hour is to encourage repeat voluntary blood donors in order to maintain safe supply of blood and its components to donors. Efforts should be made to include females in the blood donor pool by increasing awareness and through dedicated efforts to improve female health and nutrition.

scholarly journals Seroprevalence and trends of transfusion transmitted infections in blood donors of rural tertiary care hospital blood bank: a 3 year retrospective study in Chamba (HP)

2018 ◽  
Vol 5 (6) ◽  
pp. 2453
Author(s):  
Ishan Arora ◽  
Shairoly Singh ◽  
Shireen Singh
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Blood Bank ◽  
Care Hospital ◽  
Total Blood ◽  
Medical College ◽  
Disease Pattern ◽  
Donor Population

Background: Timely transfusion of blood saves millions of lives, but unsafe transfusion practices puts millions of people at risk of transfusion transmissible infections (TTIs). Blood transfusion carries the risk of transfusion-transmissible infections including human immunodeficiency virus (HIVI&II), hepatitis B virus (HBV), hepatitis C virus (HCV), malaria and syphilis. With every unit of blood there are 1% chances of transfusion associated diseases.Methods: This study was conducted over a period of 3 years (1stJanuary 2015-31st December 2017) at hospital blood bank of Pt. Jawaharlal Nehru Government Medical College, Chamba (H.P). The study was conducted on both voluntary and replacement blood donors who came to our blood bank and voluntary blood donation camps in and around Chamba. Statistical analysis used. Collected data was analyzed using appropriate statistical softwares such as EPI-INFO and MS-Excel.Results: In our study, we observed a total of 2616 donors over a period of 3 years. In the present study, 847 (32.37%) were voluntary donors and 1769 (67.62%) were replacement donors. Out of 2616 blood samples, 8 were HBsAg positive, 1 HCV positive.Conclusions: Our study shows that the number of blood donors is increasing every year. In our study, the seroprevalence of HBsAg was 0.3% and Hep C was 0.03% in total blood donors. The knowledge of current infectious disease pattern and trends in donor population can help in planning of future blood transfusion related health challenges. 

scholarly journals Frequency of Transfusion Transmitted Infection Among Blood Donors at Specialized Tertiary Care Hospital in Bangladesh

2015 ◽  
Vol 1 (1) ◽  
pp. 12-14
Author(s):  
Ferdous Ara ◽  
Zubaida Nasreen ◽  
Md Aminul Islam ◽  
Md Abdullah Yusuf ◽  
Mohammad Syaeed Hassan ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Venereal Disease ◽  
Tertiary Care ◽  
Malarial Parasite ◽  
Care Hospital ◽  
Transmitted Infection ◽  
Major Health Problem ◽  
The Status

Background: Blood transfusion is associated with a number of complications. Transfusion transmitted infections (TTI) are one of the major health problem in Bangladesh.Objective: The objective of the present study was to assess the status of transfusion transmitted infections among the apparently healthy donors.Methods: This study we carried out among 585 blood donors in the transfusion medicine department from April 2013 to March 2014 at National Institute of Neurosciences (NINS) and Hospital in Dhaka, Bangladesh. All the samples were screened for hepatitis B surface antigen (HBsAg), hepatitis C virus (HCV), human immunodeficiency virus (HIV) 1 and 2, venereal disease research laboratory test (VDRL) and malaria to see the prevalence of TTI.Results: Prevalence of hepatitis B virus (HBV), HCV, and syphilis were 1.20, 0.68 and 0.34% respectively. No blood donor tested showed positivity for malarial parasite and HIV.Conclusion: Mandatory screening of donated blood and use of sensitive screening test should be done to reduce TTI in Bangladesh.J. Natl Inst. Neurosci Bangladesh 2015;1(1):12-14

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