scholarly journals Novel Deproteinized Natural Rubber Latex Adhesive Used in Extraoral Maxillofacial Prostheses

2021 ◽  
Vol 50 (11) ◽  
pp. 3383-3394
Author(s):  
Paweena Kongkon ◽  
Wiwat Pichayakorn ◽  
Sasiwimol Sanohkan

This study aimed to develop an adhesive for silicone maxillofacial prostheses and compared the properties with the Daro adhesive hydrobond (Factor II, Inc, Lakeside, AZ, USA). Two adhesives were developed from non-vulcanized natural rubber-based adhesives (Adhesive A) and deproteinized natural rubber latex (DNRL) products (Adhesive B) and stored at 4 °C. The Control group was the commercial Daro adhesive hydrobond (Factor II, Inc, Lakeside, AZ, USA). The physical properties (appearance, viscosity, spreadability, color, and pH) of the adhesives were measured and every week for 12 weeks after storing at 4 °C. The adhesives were characterized under scanning electron microscopy. Mechanical testing done were peel bond strength and biocompatibility testing was done using MTT assay. Physical, surface, and mechanical properties were compared with the commercial adhesive. Data analysis was done using SPSS version 24. Both adhesives were physically and chemically stable at temperature 4 °C and had suitable peel bond strength adhesives as the commercial adhesive. Hence, the adhesives can be used to adhere to the maxillofacial silicone prostheses.

2018 ◽  
Vol 42 (17) ◽  
pp. 14179-14187
Author(s):  
Janisha Jayadevan ◽  
G. Unnikrishnan

Novel blend membranes from physico-chemically modified deproteinized natural rubber latex for drug release applications.


Author(s):  
Roslim Ramli ◽  
Ai Bao Chai ◽  
Shamsul Kamaruddin ◽  
Jee Hou Ho ◽  
Fatimah Rubaizah Mohd. Rasdi ◽  
...  

2013 ◽  
Vol 844 ◽  
pp. 470-473
Author(s):  
Wiwat Pichayakorn ◽  
Prapaporn Boonme ◽  
Wirach Taweepreda

This study aimed to prepare the nicotine chewing gums for smoking cessation using deproteinized natural rubber latex (DNRL) as gum bases due to its highly flexible property. The formulations were produced by the conventional heat melting and kneading methods. The experimental design was used to obtain the optimum 3 gum base formulations. Each formulation composed of olive oil as a plasticizer; sodium carboxymethylcellulose as an adsorbent; xylitol, mannitol and saccharin sodium as sweeteners instead of sugar. Gum base 1 and gum base 2 had the same sweetener amount but gum base 2 had the lower plasticizer amount, while gum base 1 and gum base 3 had the same plasticizer amount but different sweetener amount. Nicotine was added into each 3 gum bases (NCT1-3). The results showed no significant difference of appearance and taste. Their physicochemical properties were as following: pH of 8.45, 8.46, 8.54, hardness of 39.80, 36.28, 33.14 Shore A, initial modulus of 0.090, 1.260, 0.065 MPa, %elongation of 286, 403, 489%, drug content of 63.62, 70.95, 72.70%, and drug release when 500 times for force clamping of 48.72, 45.72, 67.74%, respectively. After storage at room temperature for 1 month, NCT1 and NCT2 showed unchangeable appearance, but NCT3 showed the slightly liquefied film and much sticky due to hygroscopic property of its sweetener. However, all formulations showed the significant reduction of drug amount which should be further improved in their stability properties.


2014 ◽  
Vol 936 ◽  
pp. 394-399 ◽  
Author(s):  
Ming Zhe Lv ◽  
Lei Fang ◽  
Pu Wang Li ◽  
Chun Liang Yang

Natural rubber /Zinc Oxide (NR/ZnO) nanocomposites are fabricated by blending natural rubber latex with aqueous suspension of nanoZnO particles. Its morphology and thermal/thermooxidative ageing resistance are investigated with scanning electron microscopy (SEM) and thermogravimetric analyzer (TGA). The results show that the mechanical properties of NR is greatly improved by the incorporation of nanoZnO, nanoparticles, which are homogenously distributed throughout NR matrix as nanoclusters with an average size of 80 nm when the ZnO loading is less than 4 wt%. The thermal/thermooxidative aging resistance of NR/ZnO nanocomposites is compared to the pure NR. It is found that the introduction of nanoZnO has no obvious impact to the thermal decomposing properties of NR matrix. ZnO/NR composites possess excellent antibacterial effect.


2014 ◽  
Vol 548-549 ◽  
pp. 90-95 ◽  
Author(s):  
Hamidah Harahap ◽  
Elmer Surya ◽  
Indra Surya ◽  
Hanafi Ismail ◽  
Baharin Azahari

In this study, an effect of leaching treatment on the mechanical properties of natural rubber latex (NRL) products was investigated. The products were prepared by compounding the NRL dispersion system with modified kaolin as fillers then it was formed by dipping method. It was found that incorporation of fillers in NRL would result in lowering mechanical properties of vulcanizates when the leaching was performed. The results were confirmed further by characterization of Fourier-Transform Infra-Red (FTIR) and Scanning Electron Microscopy (SEM).


2012 ◽  
Vol 51 (41) ◽  
pp. 13393-13404 ◽  
Author(s):  
Wiwat Pichayakorn ◽  
Jirapornchai Suksaeree ◽  
Prapaporn Boonme ◽  
Wirach Taweepreda ◽  
Garnpimol C. Ritthidej

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