scholarly journals PERSPECTIVAS DA NOTIFICAÇÃO OBRIGATÓRIA DE DOENÇAS AO SERVIÇO VETERINÁRIO OFICIAL

2021 ◽  
Vol 19 (1) ◽  
pp. 59-68
Author(s):  
Ana Caroline Barros Correia do Monte
Keyword(s):  
Animal Health ◽  
World Organisation

Aproximadamente de 75% das doenças infecciosas que afetam os humanos são de origem zoonótica. A saúde e a segurança das gerações animal e humana dependem, em parte, da nossa capacidade contínua de detectar, monitorar e controlar doenças e zoonoses emergentes ou reemergentes. O objetivo nesta revisão foi sintetizar as perspectivas da notificação obrigatória de doenças ao Serviço Veterinário Oficial (SVO), incluindo os instrumentos juridicamente vinculativos, a evolução e o status atual da notificação de doenças animais ao nível nacional, os benefícios e mecanismos da notificação oportuna e os fundamentos para medidas de segurança e controle de doenças. A Instrução Normativa nº 50, de 24 de setembro de 2013, dispõe sobre uma lista de doenças de notificação obrigatória (DNO) no Brasil. A lista contempla, atualmente, um total de 141 doenças, incluindo as DNO para a World Organisation for Animal Health (OIE). Das doenças da lista da OIE no Brasil, 43 estão presentes ou com infecção limitada a uma, ou mais zonas. Na base de dados zoossanitários do Brasil, apenas 13 doenças tiveram casos notificados nos últimos 3 anos disponíveis (2017, 2018 e 2019). Pesquisas indicam elevado índice de subnotificação e falta de conhecimento sobre o processo de notificação. Instruções para notificação foram aqui apresentadas. A conexão entre a saúde humana, animal e ambiental, e a necessidade de estudar as doenças em seu contexto biológico, ecológico, médico e econômico, são apontados como mecanismo para prevenção e controle de doenças, de forma a promover e garantir a saúde nacional e globalmente.

scholarly journals Development of a Safe and Highly Efficient Inactivated Vaccine Candidate against Lumpy Skin Disease Virus

Vaccines ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 4
Author(s):  
Janika Wolff ◽  
Tom Moritz ◽  
Kore Schlottau ◽  
Donata Hoffmann ◽  
Martin Beer ◽  
...  
Keyword(s):  
Skin Disease ◽  
Animal Health ◽  
Vaccine Virus ◽  
Lumpy Skin Disease ◽  
Virus Shedding ◽  
Clinical Protection ◽  
Inactivated Vaccines ◽  
Disease Free ◽  
World Organisation ◽  
Free Status

Capripox virus (CaPV)-induced diseases (lumpy skin disease, sheeppox, goatpox) are described as the most serious pox diseases of livestock animals, and therefore are listed as notifiable diseases under guidelines of the World Organisation for Animal Health (OIE). Until now, only live-attenuated vaccines are commercially available for the control of CaPV. Due to numerous potential problems after vaccination (e.g., loss of the disease-free status of the respective country, the possibility of vaccine virus shedding and transmission as well as the risk of recombination with field strains during natural outbreaks), the use of these vaccines must be considered carefully and is not recommended in CaPV-free countries. Therefore, innocuous and efficacious inactivated vaccines against CaPV would provide a great tool for control of these diseases. Unfortunately, most inactivated Capripox vaccines were reported as insufficient and protection seemed to be only short-lived. Nevertheless, a few studies dealing with inactivated vaccines against CaPV are published, giving evidence for good clinical protection against CaPV-infections. In our studies, a low molecular weight copolymer-adjuvanted vaccine formulation was able to induce sterile immunity in the respective animals after severe challenge infection. Our findings strongly support the possibility of useful inactivated vaccines against CaPV-infections, and indicate a marked impact of the chosen adjuvant for the level of protection.

scholarly journals Molecular Characterisation of the GdhA- Derivative of Pasteurella multocida B:2

2021 ◽  
Vol 44 (1) ◽  
Author(s):  
Farahani Muhammad Azam ◽  
Mohd. Zamri-Saad ◽  
Raha Abdul Rahim ◽  
Pramote Chumnanpuen ◽  
Teerasak E-kobon ◽  
...  
Keyword(s):  
Pasteurella Multocida ◽  
Vaccine Candidate ◽  
Animal Health ◽  
Proteomic Profiling ◽  
Robust Identification ◽  
Sds Page ◽  
Pcr Method ◽  
Potential Vaccine ◽  
Free Ranging ◽  
World Organisation

Pasteurella multocida B:2 is an important veterinary pathogen causing fatal and acute haemorrhagic septicaemia (HS) in bovine. A live vaccine candidate, P. multocida B:2 GDH7 was reported to enable protection in cattle and buffaloes via intranasal (i. n.) administration. This potential vaccine was also reported to be self-transmitted from the vaccinated animal to the free-ranging animals allowing wider vaccination coverage. Prior to commercialisation, this potential vaccine requires further characterisation in accordance with the authoritative guidelines from the World Organisation for Animal Health (OIE). Hence, in this study, the potential vaccine strain, P. multocida B:2 GDH7 and the virulent parent strain were characterised through genomic and proteomic profiling. A crucial first step was to develop a sensitive yet simple and robust identification test to differentiate both strains which has been achieved by the development of a precise yet straightforward PCR method. In genomic profiling, Repetitive Extragenic Palindromic sequence-PCR (REP-PCR) was manipulated and both strains have a different display of genomic DNA band patterns. Some of the major OMPs were observed and prominent immunogens of P. multocida, OmpA and OmpH were observed to be expressed differently between these strains through SDS-PAGE analysis. In conclusion, a reproducible PCR detection method has enabled differentiation of both strains. Further characterisation of these strains shows a significantly different profile through genomic and proteomic profiling.

scholarly journals Diseases of Gastropoda

2022 ◽  
Vol 12 ◽  
Author(s):  
Michelle F. O’Brien ◽  
Sarah Pellett
Keyword(s):  
Fresh Water ◽  
Food Source ◽  
Negative Impact ◽  
Animal Health ◽  
Etiological Agent ◽  
Human Consumption ◽  
Intermediate Hosts ◽  
The World ◽  
Herpesvirus 1 ◽  
World Organisation

Gastropods (class Gastropoda) form the largest of the classes in the phylum Mollusca and inhabit terrestrial, fresh water and marine environments. A large number of these species are of major conservation importance and are an essential component of ecosystems. Gastropods may be deemed as pests, having a negative impact in horticulture and agriculture, whereas others may be used as a food source for human consumption and therefore are beneficial. Gastropods are susceptible to primary diseases and also act as intermediate hosts for diseases which affect other animals, including humans. The diseases described include two that are notifiable to the World Organisation for Animal Health (OIE): Xenohaliotis californiensis and Abalone viral ganglioneuritis caused by Haliotid herpesvirus-1 (HaHV-1). Research into the diseases of gastropods has often focused on those species that act as intermediate disease hosts, those that are used in research or those cultured for food. In this paper we review the viral, bacterial, fungal, parasitic and miscellaneous conditions that have been reported in gastropods and mention some of the factors that appear to predispose them to disease. The pathogenicity of a number of these conditions has not been fully ascertained and more research is needed into specifying both the etiological agent and significance in some of the diseases reported.

Socio-Economic Impacts of Foot and Mouth Disease Among Cattle Farmers in Sagaing and Mandalay Areas, Myanmar

2014 ◽  
Author(s):  
Ai Thanda Kyaw
Keyword(s):  
Smallholder Farmers ◽  
Economic Impacts ◽  
Animal Health ◽  
Lao Pdr ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Economic Costs ◽  
Foot And Mouth ◽  
World Organisation ◽  
Control And Eradication

The World Organisation for Animal Health (OIE) Sub-Regional Representation for South East Asia (OIE SRR-SEA) implemented the Stop Transboundary Animal Diseases and Zoonoses (STANDZ) Programme funded by AusAID to strengthen the veterinary services and effectively manage the control and eradication of foot and mouth disease (FMD) in Cambodia, Lao PDR and Myanmar. The purpose of the study is to understand how FMD outbreaks impact smallholder farmers, both men and women, at the household and village level and how control and eradication of FMD would benefit them. Specific aims are to estimate the direct and indirect socio-economic costs associated with the outbreaks of FMD as well as of the measures taken by farmers to deal with such outbreaks and to identify issues that contributed to the socio-economic impacts of FMD outbreaks and opportunities to reduce them.

scholarly journals Rapidly assessing the risks of infectious diseases to wildlife species

2019 ◽  
Vol 6 (1) ◽  
pp. 181043 ◽  
Author(s):  
Wendy Beauvais ◽  
Steffen Zuther ◽  
Chantal Villeneuve ◽  
Richard Kock ◽  
Javier Guitian
Keyword(s):  
Animal Health ◽  
Foot And Mouth Disease ◽  
Spatial And Temporal Scales ◽  
Seasonal Movement ◽  
Wildlife Species ◽  
Mouth Disease Virus ◽  
Different Types ◽  
Risk Managers ◽  
World Organisation

Predicting the likelihood of rare events is increasingly demanded by risk managers. A key challenge is dealing with different types of uncertainty, including epistemic uncertainties (lack of knowledge), stochasticity (inherent randomness) and natural variation. One potentially catastrophic event which is impacted by high levels of all three of these uncertainty types is the transmission of livestock pathogens to wildlife, particularly for endangered species. There is often a lack of basic information, e.g. about a given pathogen's presence in local livestock populations or the susceptibility of a given wildlife species to infection by the pathogen. We adapted the OIE (World Organisation for Animal Health) risk assessment framework to rapidly assess and prioritize the risks of livestock pathogens for wildlife, taking account of epistemic uncertainties, stochasticity, seasonal movement of animals and interaction between different species at different spatial and temporal scales. We demonstrate the approach using the endangered saiga antelope ( Saiga tatarica tatarica ) as a case study. We conclude that, in general, transmission events are likely to be rare and limited to small geographical areas; however, their impact could be high. Brucella spp. and foot-and-mouth disease virus are among those most likely to be transmitted from livestock to the Betpak-Dala saiga population.

Sign in / Sign up

Export Citation Format

Share Document