scholarly journals An assessment of cerebral venous thrombosis risk factors and associated clinical outcomes in Jazan region, Saudi Arabia

Neurosciences ◽  
2021 ◽  
Vol 26 (1) ◽  
pp. 15-20
Author(s):  
Hasan M. Daghriri ◽  
Alwaleed A. Alrajhi ◽  
Khadijah S. Aburasain ◽  
Ebtisam A. Ateya ◽  
Mohammed A. Hakami ◽  
...  
Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 276-276
Author(s):  
Gili Kenet ◽  
Fenella Kirkham ◽  
Thomas Niederstadt ◽  
Karin Kurnik ◽  
Rosemarie Schobess ◽  
...  

Abstract Background: Risk factors for cerebral venous thrombosis (CVT) in children include local and systemic underlying conditions, drug toxicity, and hereditary prothrombotic risk factors. Their relevance to the risk of a second venous thrombosis (VT), compared with other clinical, neuroimaging and treatment variables, is unknown. Methods: 330 of 407 consecutively enrolled CVT-patients aged newborn to <18 years (median 5.3 years; male 55%) were prospectively followed for a median (range) of 33 (12–84) months. In accordance to international treatment guidelines, 259 children (78.5%) received acute antithrombotic therapy (AT) with UFH or LMWH, followed by long-term AT with LMWH or warfarin in 218 cases (66.0%). Findings: Recurrent VT was diagnosed in 19 of 330 children (5.8%) at a median (range) age of 6 (0.5–84) months following CVT, with no difference observed between the study centres (p=0.84). Multivariate Cox regression analysis revealed that the risk of recurrence was significantly higher in those with older age at first CVT onset (p=0.02), those in whom AT was not administered prior to recurrence (p=0.0003), those who did not have complete patency rates on repeat venography at 3–6 months (p=0.01), and those subjects carrying the factor II G20210A mutation (p=0.03). Interpretation: Age at CVT onset, administration of AT, poor patency rates, and the factor II G20210A variant were of relevance to recurrent VT in children with CVT. Until evidence-based data derived from randomized treatment trials are available the message of this follow-up study is to administer any AT prophylaxis on an individual patient basis in paediatric CVT cases in newly identified VT risk situations.


2021 ◽  
Vol 42 (2) ◽  
pp. 213-218
Author(s):  
Abdullah S. Alamri ◽  
Mohammed F. Almuaigel ◽  
Zafar Azra ◽  
Foziah J. Alshamrani ◽  
Noor M. AlMohish ◽  
...  

2011 ◽  
Vol 26 (1) ◽  
pp. 13-19
Author(s):  
I. Sanz Gallego ◽  
B. Fuentes ◽  
P. Martínez-Sánchez ◽  
E. Díez Tejedor

2011 ◽  
Vol 127 ◽  
pp. S129
Author(s):  
M. Kostal ◽  
P. Dulicek ◽  
J. Maly ◽  
D. Krajickova ◽  
F. Vrbacky ◽  
...  

2018 ◽  
Vol 86 (9) ◽  
pp. 2939-2945
Author(s):  
MONA H. DEWIDAR, M.Sc.; MOHAMMED ADEL EL-TOMEY, M.D. ◽  
WAEL AHMED FADEL, M.D.; TAREK MOHAMMED EL-GAMMAL, M.D.

Author(s):  
L.A. Belova ◽  
V.V. Mashin ◽  
A.I. Sitnikova ◽  
D.V. Belov

The review presents the main risk factors for cerebral venous thrombosis (CVT). It outlines current understanding of their role in the pathogenesis of venous strokes. The purpose of the review is to systematize the CVT risk factors according to their effect on a particular component of the Virchow’s triad. Pubmed and eLIBRARY, as well as publications and papers on the issue were considered to be the main sources. As a rule, CVT is a multifactorial disease, which is more typical for young people, more often women. However, it can also occur in children and elderly patients. Since CVT does not always have a specific onset, knowledge of risk factors can help in the early disease diagnostics. In comparison with arterial thrombosis, CVT prognosis is generally more favorable. However, the consequences of the disease remain in 15–30 % of patients. The article presents the factors influencing CVT prognosis and outcome. It is considered, that such patients require timely detection and early diagnostics, as it will increase treatment efficacy, reduce after-effects and mortality. Keywords: cerebral venous thrombosis, risk factors, deep vein thrombosis, superficial vein thrombosis, venous stroke. В обзоре представлены основные факторы риска развития церебральных венозных тромбозов (ЦВТ). Обсуждаются современные представления о роли этих факторов в патогенезе венозных инсультов. Целью данного обзора является систематизация факторов риска ЦВТ в зависимости от влияния на тот или иной компонент триады Вирхова. В качестве источников информации использовались данные электронных библиотек Pubmed, eLIBRARY , а также публикации и статьи по данной проблеме. ЦВТ представляет собой, как правило, мультифакторное заболевание, более характерное для лиц молодого возраста, чаще женского пола, но также встречающееся у детей и пожилых пациентов. Поскольку ЦВТ не всегда имеет специфическое начало, знание факторов риска может помочь в ранней диагностике этого заболевания. Прогноз при ЦВТ, по сравнению с артериальным тромбозом, в целом более благоприятный. Однако у 15–30 % пациентов остаются последствия данного заболевания. В статье представлены факторы, влияющие на прогноз и исход ЦВТ. Постулируется, что указанная категория пациентов требует своевременного распознавания и ранней диагностики заболевания, что будет способствовать повышению эффективности лечения, уменьшению последствий патологии и снижению летальности. Ключевые слова: церебральный венозный тромбоз, факторы риска, тромбоз глубоких вен, тромбоз поверхностных вен, венозный инсульт.


2014 ◽  
Vol 133 ◽  
pp. S63
Author(s):  
A. Rachieru ◽  
C. Panea ◽  
S. Petrescu

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Henry Robayo-Amortegui ◽  
Natalia Valenzuela-Faccini ◽  
Cesar Quecano-Rosas ◽  
Darlyng Zabala-Muñoz ◽  
Michel Perez-Garzon

Abstract Background The new coronavirus disease 2019 pandemic has spread throughout most of the world. Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus disease 2019 infection. Case presentation We report the case of a Hispanic woman with Down syndrome who has coronavirus disease 2019 and presents as a complication extensive cerebral venous thrombosis. Conclusions Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus disease 2019 infection. In the absence of clinical and epidemiological data, it is important to carry out further investigation of the risk factors and pathophysiological causes related to the development of cerebrovascular thrombotic events in patients with Down syndrome with coronavirus disease 2019 infection.


2016 ◽  
Vol 11 (1) ◽  
pp. 28-32
Author(s):  
Camelia C. DIACONU ◽  
◽  
Mădălina ILIE ◽  
Mihaela Adela IANCU ◽  
◽  
...  

Upper extremity deep venous thrombosis is a condition with increasing prevalence, with high risk of morbidity and mortality, due to embolic complications. In the majority of the cases, thrombosis involves more than one venous segment, most frequently being affected the subclavian vein, followed by internal jugular vein, brachiocephalic vein and basilic vein. Upper extremity deep venous thrombosis in patients without risk factors for thrombosis is called primary deep venous thrombosis and includes idiopathic thrombosis and effort thrombosis. Deep venous thrombosis of upper extremity is called secondary when there are known risk factors and it is encountered mainly in older patients, with many comorbidities. The positive diagnosis is established only after paraclinical and imaging investigations, ultrasonography being the most useful diagnostic method. The most important complication, with high risk of death, is pulmonary embolism. Treatment consists in anticoagulant therapy, for preventing thrombosis extension and pulmonary embolism.


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