About syphilitic diseases of internal organs

1930 ◽  
Vol 26 (1) ◽  
pp. 15-31
Author(s):  
R. A. Luria
Keyword(s):  
Medical Science ◽  
Chronic Infections ◽  
Internal Organs

The very fact that I have the high honor to speak here, in the oldest center of medical science, in Utrecht, in your highly respected Society for Syphilitic Diseases of Internal Organs, testifies to the great interest and significant urgency of the problem of visceral syphilis. Three chronic infections are the cause of a large number of lesions of internal organs - tuberculosis, malaria and syphilis - and of them syphilis really deserves special attention, since it is about it that the doctor most often forgets, and meanwhile, at the time of recognizing a syphilitic disease of internal organs, it often means not only save the patient, but also experience the greatest pleasure of medical creativity and the joy of fulfilling the high duty of a doctor.

scholarly journals TO THE 100TH ANNIVERSARY OF THE NN BURDENKO VORONEZH STATE MEDICAL UNIVERSITY. THE HISTORY OF THE DEPARTMENT OF THE PROPAEDEUTIC OF INTERNAL DISEASES

2018 ◽  
Vol 73 (2) ◽  
pp. 135-140
Author(s):  
I. E. Esaulenko ◽  
A. V. Nikitin ◽  
L. V. Vasilieva ◽  
E. V. Gosteva ◽  
I. A. Starodubtseva ◽  
...  
Keyword(s):  
Medical Science ◽  
100Th Anniversary ◽  
Internal Organs ◽  
Ussr Council ◽  
Hydraulic Mechanism ◽  
History Of ◽  
The Russian Federation ◽  
Doctoral Dissertations ◽  
Council Of Ministers ◽  
Medical University

The article concerns the 100th anniversary of the Department of Propaedeutics of Internal Diseases at the NN Burdenko Voronezh State Medical University. There are several important stages in the formation of the department. The history of the development of the department of propaedeutics of internal diseases is inextricably linked with the formation of the Voronezh Medical University from the day of its foundation. During the last century, the department was headed by famous scientists-clinicians: Philosophov P.I., Kurshakov N.A., Gerke A.A., Ravich-Shcherbo V.A., and others. The national medicine owes to their work in the field of diagnosis and treatment of tuberculosis diseases of the lungs and pleura, the clinical course of adhesive pericarditis. During the postwar periods, the department was headed by professors Tumanovsky M.N., Kobyzev A.S., Safonov Yu.D. Their contribution to the development of medical science is difficult to overestimate. The doctrine of Professor Safonov Yu.D. on the bio-hydraulic mechanism of origin of heart sounds found resonance all over the world. Since 1987 to the present time the department of propaedeutics of internal diseases is headed by Professor Nikitin A.V. known as the founder of a new scientific direction in the field of non-drug treatment methods for diseases of internal organs. For his scientific contribution, Anatoly Vladimirovich was awarded the USSR Council of Ministers Prize, and was given an Honorary title «Honored Worker of the Higher School of the Russian Federation». Professor Nikitin A.V. is a famous scientist, a clinician, and a teacher who advised on 50 candidate and 5 doctoral dissertations defended afterward.

scholarly journals Cryptic Plasmodium chronic infections: was Maurizio Ascoli right?

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Wuelton Monteiro ◽  
José Diego Brito-Sousa ◽  
Aleix Elizalde-Torrent ◽  
Camila Bôtto-Menezes ◽  
Gisely Cardoso Melo ◽  
...  
Keyword(s):  
Research Community ◽  
New Drugs ◽  
Chronic Infections ◽  
Knowledge Gaps ◽  
Internal Organs ◽  
Malaria Research ◽  
Italian Physician

AbstractCryptic Plasmodium niches outside the liver possibly represent a major source of hypnozoite-unrelated recrudescences in malaria. Maurizio Ascoli, an Italian physician and scientist, suggested that infection was maintained as a result of the persistence of endoerythrocytic parasites in the circulatory bed of some internal organs, mainly the spleen. This would explain a proportion of the recurrences in patients, regardless of the Plasmodium species. Ascoli proposed a method that included the co-administration of adrenaline, in order to induce splenic contraction, and quinine to clear expelled forms in major vessels. Driven by controversy regarding safety and effectiveness, along with the introduction of new drugs, the Ascoli method was abandoned and mostly forgotten by the malaria research community. To date, however, the existence of cryptic parasites outside the liver is gaining supportive data. This work is a historical retrospective of cryptic malaria infections and the Ascoli method, highlighting key knowledge gaps regarding these possible parasite reservoirs.

scholarly journals Experimental research of Harmine hydrochloride effect on internal organs

2019 ◽  
Vol 18 (3) ◽  
pp. 598-606 ◽  
Author(s):  
Galina U Zhanaidarova ◽  
Roza Zh Yessimova ◽  
Kulash T Nurseitova ◽  
Roza B Seidakhmetova ◽  
Leila I Arystan ◽  
...  
Keyword(s):  
Adrenal Glands ◽  
Medical Science ◽  
Internal Organs ◽  
Toxic Dose ◽  
Standard Procedures ◽  
Hematoxylin And Eosin ◽  
Dose Dependent ◽  
Neutral Formalin ◽  
The Brain ◽  
Dose Dependent Effect

Objective. The purpose of thisstudy was to determine the chronic toxicity of the drug “Harmine hydrochloride, capsules” for preclinical evaluation of its safety. Materials and methods.The experiment was performed on 48 CD-1 rats. Harmine hydrochloride was injectedto the animals intragastrically at doses of 2.5 mg / kg/per day, 5 mg / kg/per day, 9 mg / kg/per day, 10 mg / kg/per day for 3 months. After 3 months, the animals were withdrew from the experiment, internal organs (brain, heart, spleen, adrenals) were weighed and set in 10% neutral formalin. Histological specimenswere mounted in accordance with standard procedures. Results and Discussion. All morphological, histopathological changes, in addition to mortality and bodyweight changes were recorded.Microtome cuts, 5 micrometers thick, were stained with hematoxylin and eosin. Conclusion. As a result of the morphological study, there was no toxic effect of harmine hydrochloride at doses of 2.5 mg / kg, 5 mg / kg, 9 mg / kg and 10 mg / kg on the brain, at doses of 2.5 mg / kg and 5 mg / kg on the structure of the heart, spleen and adrenal glands. At doses of 9 mg / kg and 10 mg / kg, there is an initial toxic dose-dependent effect on the heart, spleen and adrenal glands. Bangladesh Journal of Medical Science Vol.18(3) 2019 p.598-606

scholarly journals Pathological Aspects of Haemonchosis in Goats and Sheeps

2020 ◽  
Vol 30 (2) ◽  
Author(s):  
Riza Zainuddin Ahmad ◽  
Rida Tiffarent
Keyword(s):  
Haemonchus Contortus ◽  
Mononuclear Cells ◽  
Clinical Symptoms ◽  
Severe Anaemia ◽  
Economic Losses ◽  
Pathological Findings ◽  
Chronic Infections ◽  
Internal Organs ◽  
Large Numbers ◽  
High Prevalence

<p class="awabstrak2">Haemonchosis in sheep and goats has a high prevalence rate in several regions in Indonesia and causes economic losses. The purpose of this paper is to explain the clinical symptoms and pathological aspects of <em>Haemonchus contortus</em> infection so that knowledge is expected to help in controlling haemonchosis. Clinical symptoms of haemonchosis is characterised by decreased production, cachexia, and severe anaemia due to worms that sucking blood from the abomasal mucosa. In chronic infections the symptoms shows general oedema. Gross pathological findings are pale mucosa and carcass, hydrothorax, ascites, and haemorrhagic abomasum. Whereas histopathological features shows desquamation of villous abomasum, extensive hemorrhage of abomasal mucosa-submucosa, infiltration of large numbers of eosinophil and mononuclear cells, and cells undergoing degeneration and necrosis of internal organs.  In general, the above exposure will show that haemonchosis usually associated with anaemia, cachexia, oedema, haemorrhage, infiltration of eosinophil and mononuclear cells in the abomasal mucosa.</p>

Spiritual Healing, Sick Kids and the Law: Inequities in the American Healthcare System

2003 ◽  
Vol 29 (2-3) ◽  
pp. 269-299
Author(s):  
Janna C. Merrick
Keyword(s):  
Medical Science ◽  
Spiritual Healing ◽  
Best Interests ◽  
Legal Rights ◽  
High Tech ◽  
Divine Love ◽  
Religious Minority ◽  
Human Need ◽  
East End ◽  
The Church

Main Street in Sarasota, Florida. A high-tech medical arts building rises from the east end, the county's historic three-story courthouse is two blocks to the west and sandwiched in between is the First Church of Christ, Scientist. A verse inscribed on the wall behind the pulpit of the church reads: “Divine Love Always Has Met and Always Will Meet Every Human Need.” This is the church where William and Christine Hermanson worshipped. It is just a few steps away from the courthouse where they were convicted of child abuse and third-degree murder for failing to provide conventional medical care for their seven-year-old daughter.This Article is about the intersection of “divine love” and “the best interests of the child.” It is about a pluralistic society where the dominant culture reveres medical science, but where a religious minority shuns and perhaps fears that same medical science. It is also about the struggle among different religious interests to define the legal rights of the citizenry.

Left Ventricular Hypertrophy

2014 ◽  
Vol 19 (2) ◽  
pp. 11-15
Author(s):  
Steven L. Demeter
Keyword(s):  
Risk Factors ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Mass Index ◽  
Medical Science ◽  
Careful Analysis ◽  
Left Ventricular ◽  
Hypertensive Disease ◽  
Accurate Analysis ◽  
Clear Explanation

Abstract The fourth, fifth, and sixth editions of the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides) use left ventricular hypertrophy (LVH) as a variable to determine impairment caused by hypertensive disease. The issue of LVH, as assessed echocardiographically, is a prime example of medical science being at odds with legal jurisprudence. Some legislatures have allowed any cause of LVH in a hypertensive individual to be an allowed manifestation of hypertensive changes. This situation has arisen because a physician can never say that no component of LVH was not caused by the hypertension, even in an individual with a cardiomyopathy or valvular disorder. This article recommends that evaluators consider three points: if the cause of the LVH is hypertension, is the examinee at maximum medical improvement; is the LVH caused by hypertension or another factor; and, if apportionment is allowed, then a careful analysis of the risk factors for other disorders associated with LVH is necessary. The left ventricular mass index should be present in the echocardiogram report and can guide the interpretation of the alleged LVH; if not present, it should be requested because it facilitates a more accurate analysis. Further, if the cause of the LVH is more likely independent of the hypertension, then careful reasoning and an explanation should be included in the impairment report. If hypertension is only a partial cause, a reasoned analysis and clear explanation of the apportionment are required.

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