Functional state of the liver in patients with dumping syndrome

1980 ◽  
Vol 61 (6) ◽  
pp. 37-39
Author(s):  
V. F. Bogoyavlenskiy ◽  
A. G. Oparin ◽  
R. M. Gazizov
Keyword(s):  
Blood Serum ◽  
Functional State ◽  
Early Identification ◽  
Serum Enzymes ◽  
Dumping Syndrome ◽  
Liver Lesions ◽  
Functional Tests

56 patients with dumping syndrome were examined. In 44 people, an increase in the activity of the isozymes LDH5,4, MDG3, ALP3, 1, CF1, AST2 was found to decrease the activity of the fourth fraction of esterases, while in 18 of them clinically, according to the results of widely used functional tests, no changes in the liver were detected. This gives grounds to recommend the study of the activity of hepatic isoenzymes LDH, MDH, ALP, CF, ACT esterases for early. identification of liver lesions in dumping syndrome in patients with resected patients; keywords: dumping syndrome, liver, blood serum enzymes.

scholarly journals Blood Serum Enzymes Within the Estrous Cycle

1967 ◽  
Vol 50 (8) ◽  
pp. 1341-1342 ◽  
Author(s):  
J.D. Roussel ◽  
O.T. Stallcup
Keyword(s):  
Blood Serum ◽  
Estrous Cycle ◽  
Serum Enzymes

scholarly journals ANALYSIS OF THE EFFICIENCY OF COMPLEX TREATMENT OF PATIENTS WITH GENERALIZED PERIODONTITIS ACCORDING TO THE CHANGES IN THE ACTIVITY OF BLOOD SERUM ENZYMES

2021 ◽  
pp. 38-43
Author(s):  
H.M. Melnychuk ◽  
R.S. Kashivska ◽  
H.D. Semeniuk ◽  
N.I. Shovkova ◽  
A.S. Melnychuk ◽  
...  
Keyword(s):  
Blood Serum ◽  
Serum Enzymes ◽  
Arginase Activity ◽  
Healthy People ◽  
Comprehensive Treatment ◽  
Complex Treatment ◽  
Strong Correlations ◽  
Initial Degree ◽  
Activity Of Enzymes ◽  
The Difference

Introduction. The mechanisms of generalized periodontitis (GP) development and methods of its treatment remain obscure, so it is important to study changes in the activity of enzymes responsible for maintaining homeostasis, as well as the inclusion of medicines that regulate them into the complex treatment. Aim of research is to study the influence of comprehensive treatment in patients with GP on the dynamics of the activity of indicator blood serum enzymes in different observation periods. Methods. There were examined 29 people with a healthy periodontium and 143 patients with GP aged 19-45 years, somatically healthy, before, immediately after the treatment, after 6 and 12 months. Patients were divided into subgroups with chronic (A) and acute (B) course: IA and IB – the initial degree; IIA and IIB – the I degree; IIIA and IIIB – the II degree. The activity of lactate-dehydrogenase (LDG), arginase and sorbitol dehydrogenase (SDG) in blood serum has been studied. In addition to the basic periodontal therapy, the microalgal medicine Spirulina platensis was prescribed endogenously, and the paste with the same amount of spirulina powder and enterosorbent and 0.05% chlorhexidine bigluconate solution was exogenously prescribed. Results. In patients with IA and IB subgroups, LDG activity has increased in 1.37- and 1.48-times (p1 <0.01; p1 = 0.001). Under the influence of treatment, it has decreased in all patients, especially after 6 months – in 1.33- and 1.50-times (p2<0.001), but after 12 months it has been increased more (p2> 0.05; p2 <0.05). Arginase activity in IA and IB subgroups has reduced in 1.23- and 1.31-times (p1<0.05; p1=0.005). Due to the therapy, it has increased immediately, after 6 and 12 months, respectively in 1.23- and 1.26-times; in 1.21- and 1.25-times, and in 1.20-1.23-times (p2<0.05; p2> 0.05; p1> 0.05). In subgroups IA and IB, SDG activity has increased in 1.15- and 1.17-times (p1> 0.05), and after the treatment it has decreased immediately in 1.14- and 1.16-times (p2 <0.05); later it increased, but differed slightly from the norm (p1> 0.05). LDG activity in subgroups IIA and IIB has increased in 1.38- and 1.54-times (p1 <0.01; p1=0.001). After the treatment in subgroup IIA, it has decreased in 1.21-times immediately and after 6 months (p2<0.005), and a year later it has increased (p2>0.05; p1>0.05); in subgroup IIB it has decreased in 1.33-, 1.39- and 1.24-times (p2<0.05; p2<0.01; p2 <0.05 and p1> 0.05). In subgroups IIA and IIB, arginase activity has reduced in 1.32-times (p1=0.001). Immediately after the treatment in subgroup IIA, it has increased in 1.21-times (p2=0.005), and subsequently decreased (p2> 0.05). In the IIB subgroup, its increasing was 1.31-, 1.27- and 1.25-times (p2 <0.05), and the difference with the norm was insignificant. SDG activity in subgroups IIA and IIB has increased in 1.18- and 1.24-times (p1 <0.05; p1=0.01). After the treatment, it has decreased at all terms in both subgroups similarly: 1.13- and 1.16-times; 1.17- and 1.17-times; 1.12- and 1.10-times (p2 <0.05; p2 <0.05; p2> 0.05) and it differed slightly from normal one. The largest increase in LDG activity was found in subgroups IIIA and IIIB – 1.45- and 1.62-times (p1≤0.001). As a result of therapy immediately, after 6 and 12 months it has decreased in 1.18- and 1.20-times; 1.26- and 1.23-times; 1.13- and 1.15-times (p2 <0.05; p2 <0.05; p2> 0.05; p1> 0.05). In subgroups IIIA and IIIB, arginase activity has reduced in 1.32- and 1.37-times (p1≤0.005). Treatment has increased the indices in group IIIA in 1.22-, 1.22- and 1.18-times (p2<0.05), and in group IIIB it immediately increased in 1.25-times and then decreased (p2 <0.05; p2> 0.05). The activity of SDG in IIIA and IIIB subgroups has increased in 1.31-times (p1=0.001). Under the influence of therapy in subgroup IIIA, it has decreased immediately, after 6 and 12 months in 1.17-, 1.22- and 1.13-times (p2 <0.05; p1> 0.05), and in subgroup IIIB it initially decreased, but after a year it has increased (p2>0.05) and the difference with healthy people became significant. The altered indices of activity of enzymes studied in patients with GP did not exceed the reference values, but showed a violation of the enzyme system, which was regulated by the treatment. Prior to therapy, reliable (p<0.05-0.005) strong correlations were found between these parameters: LDG with SDG (r> 0.71) and arginase with SDG (r> -0.90). After the treatment, they were not found, six months later one correlation has restored, and a year later – both have restored, which indicates the necessity for the maintenance of endogenous therapy after six months. Conclusion. GP is accompanied by significant (p1<0.05-0.001) changes in the enzymes activity in the blood: in LDG and SDG, it is increased, and in arginase – it is reduced. Comprehensive treatment has regulated these disorders, especially immediately and after 6 months (p2<0.05-0.001). The activity of LDG and SDG of the initial and the I degree immediately and after 6 months and arginase at the initial degree after 6 and 12 months became the closest to norm. In the GP of the II degree, the data of healthy people were not achieved, but the difference with them was insignificant (p1> 0.05).

scholarly journals Clinical-biochemical status of hens due to changes of battery cages height location

2021 ◽  
Vol 9 (3) ◽  
pp. 130-134
Author(s):  
M. I. Sakhatsky ◽  
Yu. V. Osadcha
Keyword(s):  
Blood Serum ◽  
Chronic Stress ◽  
Biochemical Parameters ◽  
Physiological State ◽  
Serum Enzymes ◽  
The Body ◽  
Gamma Glutamyl Transferase ◽  
Biochemical Status ◽  
Battery Cages ◽  
Glutamyl Transferase

In the conditions of industrial poultry farming, the body of hens is constantly exposed to numerous technological stressors, the least studied of which are long-term ones, that can provoke chronic stress. One such technological stressor is an increase in the level of cage equipment, which is used by producers to obtain a larger amount of products from 1 m2 of poultry area. The aim of this work was to study the physiological state of the hen’s body based on the clinical biochemical analysis of their blood serum, depending on the battery cages height. In the conditions of a modern complex for the production of edible eggs in a poultry house with an area of 2 915 m2, 4 groups of hens were formed, each of them was kept on a separate floor-analogue in terms of area and cage equipment. Each floor was equipped with «Big Dutchman» 3-tier battery cages. Battery cages of each floor were separated from each other by a lattice floor so that cages of 1–3 tiers entered up to the 1st floor, 4–6 tiers – up to the 2nd, 7–9 tiers – up to the 3rd, and 10–12 tiers – up to 4th floor of cage equipment. Biochemical parameters and activity of hens blood serum enzymes were determined on a BioChem FC-360 biochemical analyzer. For this, 30 blood samples with a volume of 1.0–1.5 ml were taken from axillary veins of laying hens in each group at the age of 18 weeks (at the beginning of the study) and at 52 weeks. It was found that increasing the layering of cage equipment does not have a negative impact on the hen’s body. So, for keeping hens in cages of multi-tier battery cages located on floors 2–4 (4–12 tiers), the biochemical status and activity of their blood serum enzymes were within the physiological norm. Whereas, for hens kept in battery cages of the a multi-tiered system on the 1st floor there was an increase in glucose levels of 60.5–71.0%, creatinine – by 9.7–12.3%, phosphorus – 82.6–100.0%, was observed a decrease in calcium to phosphorus ratio 46.7–50.0%, which was confirmed by an increase in the activity of alkaline phosphatase by 22.3–27.0%, as well as an increase in the activity of aspartate aminotransferase by 3.2–13.8%, lactate dehydrogenase - by 48.5–65.1% and gamma-glutamyl transferase – by 16.4–20.6%. It has been proven that the main consequences of chronic stress caused by keeping hens in the lower floor cells of the multi-tiered battery cage are reflected in the biochemical parameters of their serum, namely increased glucose, creatinine, enzyme activity and violation of calcium to phosphorus ratio.

scholarly journals Activity of blood serum enzymes in seasonal generations of the bank vole

1980 ◽  
Vol 25 ◽  
pp. 377-384 ◽  
Author(s):  
Elżbieta Wołk ◽  
Elżbieta Józefczak
Keyword(s):  
Blood Serum ◽  
Bank Vole ◽  
Serum Enzymes

scholarly journals The choice of surgical treatment of malignant liver lesions, depending on the functional state future liver remnant

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S903
Author(s):  
A. Shabunin ◽  
D. Grekov ◽  
M. Tavobilov ◽  
P. Drozdov ◽  
A. Belousova
Keyword(s):  
Surgical Treatment ◽  
Functional State ◽  
Future Liver Remnant ◽  
Liver Lesions ◽  
Liver Remnant ◽  
Malignant Liver ◽  
Malignant Liver Lesions
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