scholarly journals Diagnostic value of the determination of protein fractions and sialic acid in the disease "no pulse"

2021 ◽  
Vol 43 (3) ◽  
pp. 55-57
Author(s):  
S. G. Klyuchareva
Keyword(s):  
Sialic Acid ◽  
Young People ◽  
Diagnostic Value ◽  
Protein Fractions ◽  
Inflammatory Infiltration ◽  
Chronic Course ◽  
Large Vessels

The essence of the disease "lack of pulse" is the progressive panarteritis of large vessels with their inflammatory infiltration, gradual hardening and desolation. This disease belongs to the group of collagen, with which it has in common in pathogenesis, recurrent chronic course, predominant lesion of young people.

scholarly journals The clinical significance of the determination of sialic acid and protein fractions in chronic nonspecific lung diseases

2021 ◽  
Vol 43 (3) ◽  
pp. 57-58
Author(s):  
V. I. Novichkov
Keyword(s):  
Sialic Acid ◽  
Clinical Significance ◽  
Clinical Picture ◽  
Lung Diseases ◽  
Inflammatory Process ◽  
Protein Fractions ◽  
Foreign Literature

In the domestic and foreign literature available to us, we did not find data on the content and dynamics of sialic acid in chronic nonspecific lung diseases. In this regard, we decided to conduct observations and compare the results obtained with the clinical picture and such indicators of the inflammatory process as ROE and the number of leukocytes, as well as with protein fractions, which were determined by electrophoresis on paper.

Is Quantitative Determination of Fibrin(ogen) Degradation Products and Thrombin-Antithrombin III Complexes Useful to Diagnose Deep Venous Thrombosis in Outpatients?

1989 ◽  
Vol 62 (04) ◽  
pp. 1043-1045 ◽  
Author(s):  
Paul F M M van Bergen ◽  
Eduard A R Knot ◽  
Jan J C Jonker ◽  
Auke C de Boer ◽  
Moniek P M de Maat
Keyword(s):  
Quantitative Determination ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Antithrombin Iii ◽  
Degradation Products ◽  
Family Doctor ◽  
Diagnostic Value ◽  
Impedance Plethysmography ◽  
Fibrin Degradation Products

SummaryWe studied the diagnostic value of recently introduced ELISA’s for the determination of thrombin-antithrombin III (TAT) complexes, fibrin degradation products (FbDP), fibrinogen degradation products (FgDP) and total degradation products (TDP) for deep venous thrombosis (DVT) in plasma of 239 consecutive outpatients, suspected for DVT by their family doctor. DVT was confirmed by impedance plethysmography in 60 patients. Using the 95th percentile range of 42 healthy volunteers the sensitivity for the detection of DVT was: 37% for TAT, 95% for TDP, 92% for FbDP and 90% for FgDP. Specificity was: 88% for TAT, 16% for TDP, 20% for FbDP and 25% for FgDP.We conclude that these assays are of little value in the diagnosis of DVT in outpatients.

GASCHROMATOGRAPHIC DETERMINATION OF STEROIDS IN THE URINE OF PATIENTS WITH CUSHING'S SYNDROME

1971 ◽  
Vol 67 (2) ◽  
pp. 303-315 ◽  
Author(s):  
A. J. Moolenaar ◽  
A. P. van Seters
Keyword(s):  
Liquid Chromatography ◽  
Cushing’S Syndrome ◽  
Normal Subjects ◽  
Diagnostic Value ◽  
Cushing's Syndrome ◽  
Gas Liquid Chromatography ◽  
Obese Subjects

ABSTRACT The 17-oxosteroids were estimated in the urine of 27 patients with Cushing's syndrome by gas-liquid chromatography (G. L. C.). The values of the various steroid fractions are compared with those of normal subjects, patients with thyrotoxicosis and obese subjects. The effect of the age of the patients on the diagnostic value of the invidual 17-oxosteroids and their ratios is discussed.

COMPARATIVE ACTION OF VARIOUS OESTROGENIC COMPOUNDS ON MOUSE VAGINAL SIALIC ACIDS (II)

1969 ◽  
Vol 62 (4) ◽  
pp. 663-670 ◽  
Author(s):  
Lars Carlborg
Keyword(s):  
Sialic Acid ◽  
Response Curve ◽  
Sialic Acids ◽  
Clear Cut ◽  
Suitable Parameter ◽  
Sufficient Degree ◽  
Comparative Action ◽  
Relative Potencies ◽  
Good Agreement

ABSTRACT Oestrogens administered in lower doses than necessary to induce full cornification of the mouse vagina induce mucification. It was shown previously that the degree of mucification could be estimated by quantitative determination of sialic acids. A suitable parameter for oestrogen assay was the measurement of vaginal sialic acid concentration which exhibited a clear cut dose response curve. Eleven assays of various oestrogens were performed with this method. Their estimated relative potencies were in good agreement with other routine oestrogen assays. A statistically sufficient degree of precision was found. The sensitivity was of the same order, or slightly higher, than the Allen-Doisy test.

scholarly journals Evaluation of free and total L-thyroxine in serum by a commercial procedure.

1981 ◽  
Vol 27 (1) ◽  
pp. 149-152 ◽  
Author(s):  
M J Obregon ◽  
A Kurtz ◽  
R Ekins ◽  
G Morreale de Escobar
Keyword(s):  
Pregnant Women ◽  
Plasma Proteins ◽  
Diagnostic Value ◽  
Free Thyroxine ◽  
Total Thyroxine ◽  
Dialysis Method ◽  
Hypothyroid Patients ◽  
Hyperthyroid Patients ◽  
Normal Controls

Abstract We assessed a commercial kit (Corning Medical) for "free" and total thyroxine determination, results being compared to those obtained by the Ekins and Ellis dialysis method (free thyroxine) and the method of Weeke and Orskov (total thyroxine). The kit procedure permits determination of both free and total thyroxine within 4 to 5 h, and the combined results may disclose changes in binding to plasma proteins that would be missed if only free thyroxine were determined. With both free-thyroxine methods, the values distinguished hyperthyroid patients from normal controls and pregnant women with 100% accuracy, but there was some overlap between hypothyroid patients and controls. Absolute values with the kit procedure often exceed those obtained by dialysis, especially for hypothyroid patients and pregnant women. We conclude that the kit may be of as much diagnostic value as the dialysis method if the limitations regarding absolute values are kept in mind and the test is not used as a substitute for thyrotropin determinations in cases of suspected hypothyroidism.

PATENT DUCTUS ARTERIOSUS WITH REVERSAL OF FLOW

PEDIATRICS ◽  
1956 ◽  
Vol 18 (3) ◽  
pp. 410-423
Author(s):  
Ray C. Anderson ◽  
Paul Adams ◽  
Richard L. Varco
Keyword(s):  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Diagnostic Value ◽  
Successful Outcome ◽  
Exertional Dyspnea ◽  
Artery Segment ◽  
Pulmonary Arterial ◽  
The Right ◽  
Patent Ductus

Ten cases are presented of children having patent ductus arteriosus with reversal of shunt. Cyanosis, often greater in the toes, was present in all. Exertional dyspnea developed early. Murmurs were of no diagnostic value, but an accentuated pulmonic second sound was uniformly present. Right ventricular preponderance was found in all cases on the electrocardiogram. Cardiac size varied on roentgenography, but there was usually prominence of the pulmonary artery segment. Six cases showed evidence of bi-directional shunts, one showed only a reversed shunt, while data were insufficient to determine this point in the remaining three. Three patients had surgery, one with a successful outcome. The latter was a 1-year-old infant in whom lung biopsy at surgery revealed only minimal pulmonary arterial changes. Forty-five cases are reviewed from the literature. The majority of these occurred in adults. Twenty-two have been subjected to surgery, four with good results, three of the latter being children. The differential diagnosis is briefly discussed. The safest and simplest diagnostic test to perform is the determination of oxygen saturation of samples of blood obtained simultaneously from the right brachial and femoral arteries. Angiocardiography and cardiac catheterization also provided helpful information. The diagnosis will not be made unless the examiner keeps the entity in mind. The entity can no longer be considered rare. Surgical treatment of the condition has been very disappointing, especially in the adult. There is reason to believe that surgical intervention very early in life will yield a higher salvage rate.

scholarly journals The Diagnostic Value of Cytokeratin 7 and 20 in Determination of Primary and Metastatic Liver Tumors

2015 ◽  
Vol 25 (1) ◽  
Author(s):  
Deniz Nart ◽  
Banu Yaman ◽  
Serap Karaarslan ◽  
Murat Zeytunlu ◽  
Murat Kilic ◽  
...  
Keyword(s):  
Liver Tumors ◽  
Diagnostic Value ◽  
Cytokeratin 7 ◽  
Metastatic Liver Tumors ◽  
Metastatic Liver
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