scholarly journals Prevalence and risk factors for pelvic organ prolapse in female citizens of Baku

2018 ◽  
Vol 99 (2) ◽  
pp. 187-194
Author(s):  
M Sh Askerova ◽  
L M Rzakulieva
Keyword(s):  
Risk Factors ◽  
Secondary Education ◽  
Pelvic Organ Prolapse ◽  
Family History ◽  
Medical History ◽  
Positive Family History ◽  
Age Groups ◽  
Pelvic Organ ◽  
Physical Work ◽  
Past Medical History

Aim. Study of prevalence and risk factors of pelvic organ prolapse in females in Baku. Methods. Statistical observation unit was a woman aged 45-74 years. The sample size (710 women) was determined taking into account probable prevalence of pelvic organ prolapse (20% according to literature) and margin of error (3%). All women were invited to maternity welfare centre, and a thorough examination was performed after their written consent was obtained. Results. The proportion of women aged 45-49, 50-54, 55-59, 60-64, 65-69, and 70-74 years was 26.5±1.7, 24.9±1.6, 23.1±1.6, 10.9±1.2, 8.2±1.0 and 6.4±0.9%, respectively. Prevalence of obesity in the named groups was 31.9, 34.5, 35.4, 36.4, 27.8 and 34.8%. Proportion of women with secondary and specialized secondary education was 58.5, 58.8, 53.7, 51.9, 51.7 and 67.4% resepctively. Among women of the corresponding age groups, physical work was recorded in 47.9, 53.7, 59.8, 58.4, 13.8 and 17.4% of cases, respectively. In past medical history, no surgeries were observed in 68.1, 77.4, 73.2, 77.9, 84.5 and 84.8% of cases, resepectively. Some women had no labour in past medical history (2.1, 2.3, 2.5, 2.6, 3.5 and 4.3% in the same age groups). Statistically significantly prevalence of pelvic organ prolapse increases among those aged 60 years and older (51.6±3.6% at age 45-49 years and ≥76.6±4.8% at age 60 years and older, р=0.001), with a body mass index less than 25.0 and more than 30 kg/м2 (69.7±3.3 and 66.7±3.0%, р=0.01), with high parity and remarkable family history (63.0±2.6, р=0.01), severe connective tissue dysplasia (72.6±2.5%, р=0.001), in postmenopausal period (63.8±2.0%, р=0.01), and depending on education level (88.0±2.4% among those with pre-secondary education: р=0.001). Relative risk of pelvic organ prolapse in the population of Baku is lower compared to the literature data in the background of obesity, but is higher in the background of positive family history and depending on the amount of deliveries (p=0.05). Conclusion. In Baku 59.9±1.8% of women aged 45-75 years have pelvic organ prolapse of different severity, incomplete uterine and vaginal prolapse are more prevalent (41.3±1.8 per 100 women); prevalence of pelvic organ prolapse is higher in women aged 60 years or older compared to those aged 45-49 (76.6±4.8% vs 51.6±3.6%, р=0.001).

scholarly journals Pili Multigemini Is a Possible Risk Factor for Pilonidal Sinus Disease

2021 ◽  
Vol 105 (1-3) ◽  
pp. 30-35
Author(s):  
Yahya Ekici ◽  
Gokhan Moray
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Medical History ◽  
Pilonidal Sinus ◽  
Positive Family History ◽  
Sitting Time ◽  
Pilonidal Sinus Disease ◽  
Sinus Disease ◽  
Sitting Posture ◽  
Hair Type

The aim of this study is to analyze both previously proposed and new risk factors for the development of pilonidal sinus. This is a prospective case-control study consisting of 145 patients with pilonidal sinus disease (n = 45) and a control group (n = 100). All patients were admitted to the department of general surgery between January 2013 and May 2015. The patients' age, family history, medical history, sitting time in a day, sitting posture, body mass index (BMI), Garn hairiness score, and hair type were evaluated. There were significant differences between the groups in the following characteristics: age (P = 0.01); positive family history (P = 0.01); medical history (P = 0.01); sitting time in a day (P = 0.01); sitting posture (P = 0.01); BMI (P = 0.01); Garn score (P = 0.01); and hair type. Multivariate logistic regression analysis indicated that positive family history (P = 0.03); Garn score (P = 0.05); medical history (P = 0.01); and sitting posture (P = 0.02) were independent risk factors for the development of pilonidal sinus disease.

scholarly journals Presentation of Sudden Death in Emergency Department of a Tertiary Care Hospital of Bangladesh: A Retrospective Study

2015 ◽  
Vol 3 (1) ◽  
pp. 14-16
Author(s):  
Syed Dawood Md Taimur ◽  
M Maksumul Haq ◽  
MA Rashid ◽  
Md Rezaul Karim ◽  
Hemanta I Gomes
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Retrospective Study ◽  
Sudden Death ◽  
Medical History ◽  
Cause Of Death ◽  
Age Groups ◽  
Care Hospital ◽  
Age Group ◽  
Past Medical History

Background: The incidence and causes of sudden death vary in different societies, and these differences are influenced by demographic and clinical factors such as age, gender, risk factors, past medical history and presumed cause of death. This three years long retrospective study describes the influence of these factors on death from sudden cardiopulmonary arrest.Materials and Methods: This is a retrospective study of sudden death among all the age groups who were seen at Emergency Room (ER) of Ibrahim Cardiac Hospital & Research Institute, Dhaka, Bangladesh. Total 414 cases of death were reported between 1stJanuary, 2012 to 31st December, 2014. They were investigated retrospectively and subsequently analyzed on age, sex, risk factors, past medical history, endo-tracheal intubation with resuscitation and cause of death. The statistical analysis was performed as appropriate to illustrate any possible association between different demographic variables and cardiopulmonary arrest.Results: Out of 414 deaths, 72.5% were male, & 27.5% were female. The mean age of subjects was 60.60 ± 13.34 years with male mean age of 60.35 ± 13.62 years and female mean age of 59.70 ± 13.24 years. There were three different age groups in this study. 52 deaths were in 17-45 years of age group, 233 death patients were in 46-65 years age group & 129 deaths were more than 65 years age group. Among 46-65years age group 161 deaths were presumed to be due to cardiac cause which is higher than the other two groups. 75.12% of all the study patients had hypertension, 84.06% had diabetes mellitus, 23.43% had CKD & 69.32% had dyslipidaemia. 31.40% patients were active smoker, & 20.53% had prior h/o smoking. Patients who suffered cardiac cause of death had significant history of hypertension (p<0.001), dyslipidaemia (p<0.001), smoking habit (p<0.001), & CKD (p<0.001). 40.8% (169) of deceased patients had previous ischemic heart disease, 10.4% (43) had previous cerebrovascular disease and 28% (116) had prior morbidity like malignancy, multi organ dysfunction. 73.67% subjects needed endotracheal intubation with urgent cardio pulmonary resuscitation. Out of 414 study patients, 65% had presumed precipitating cardiac cause of death, 15% had presumed neurological cause of death and rest 20% had other causes.Conclusion: The current study indicates a definite influence of age, gender, medical risk factors and past medical history has causal relationship with sudden death. The highest incidence occurred in the middle age group as compared to other age groups. Incidence was also higher in men than in women. Subjects with hypertension, diabetes mellitus and previous coronary artery disease had higher incidence of sudden deathsBangladesh Crit Care J March 2015; 3 (1): 14-16

scholarly journals Incidence and risk factors for reoperation of surgically treated pelvic organ prolapse

2011 ◽  
Vol 23 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Patrick Dällenbach ◽  
Carol Jungo Nancoz ◽  
Isabelle Eperon ◽  
Jean-Bernard Dubuisson ◽  
Michel Boulvain
Keyword(s):  
Risk Factors ◽  
Pelvic Organ Prolapse ◽  
Pelvic Organ

scholarly journals Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

2016 ◽  
Vol 60 (1) ◽  
Author(s):  
A. Vetuschi ◽  
A. D'Alfonso ◽  
R. Sferra ◽  
D. Zanelli ◽  
S. Pompili ◽  
...  
Keyword(s):  
Risk Factors ◽  
Smooth Muscle ◽  
Pelvic Organ Prolapse ◽  
Smooth Muscle Cells ◽  
Muscularis Propria ◽  
Muscle Cells ◽  
Pelvic Organ ◽  
Vaginal Wall ◽  
Anterior Vaginal Wall ◽  
Collagen Iii

<p>The objective<strong> </strong>of this study was to evaluate the morphological and immunohistochemical alterations of tissue removed from the upper third of anterior vaginal wall in a sample group of the female population presenting homogenous risk factors associated with Pelvic Organ Prolapse (POP). The case study consisted of 14 patients with POP and there were 10 patients in the control group. Patient selection was carried on the basis of specific criteria and all of the patients involved in the study presented one or more of the recognized POP risk factors. Samples were taken from POP patients during vaginal plastic surgery following  colpohysterectomy, and from control patients during closure of the posterior fornix following hysterectomy. Samples were processed for histological and  immunohistochemical analyses for Collagen I and Collagen III, α-Smooth Muscle Actin (α-SMA), Platelet-Derived-Growth-Factor (PDGF), matrix metalloproteinase 3 (MMP3), Caspase3. Immunofluorescence analyses for Collagen I and III and PDGF were also carried out. In prolapsed specimens our results show a disorganization of smooth muscle cells that appeared to have been displaced by an increased collagen III deposition resulting in rearrangement of the muscularis propria architecture. These findings suggest that the increase in the expression of collagen fibers in muscularis could probably due to a phenotypic switch resulting in the dedifferentiation of smooth muscle cells into myofibroblasts. These alterations could be responsible for the compromising of the dynamic functionality of the pelvic floor.</p><p><strong> </strong></p>

scholarly journals Study of risk factors and its correlation with constraint induced movement therapy for atherosclerosis in patients of coronary artery disease and their offspring

2020 ◽  
Vol 7 (3) ◽  
pp. 446
Author(s):  
Venugopal Margekar ◽  
Shweta Thakur ◽  
O. P. Jatav ◽  
Pankaj Yadav
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Positive Family History ◽  
Surrogate Marker ◽  
Control Group ◽  
Medical College ◽  
Constraint Induced Movement Therapy ◽  
Group Data ◽  
History Of ◽  
Artery Disease

Background: A significant percent of cardiovascular event occurs without well-known modifiable risk. A new tool for early identification for atherosclerosis is required for early intervention. Aims and objectives of the study was to study the risk factors for CAD and its correlation with CIMT.Methods: One hundred and forty subjects were studied for the risk factors of CAD in Department of Medicine of G.R. Medical College, Gwalior from 2012 to 2013. Out of 140 subjects, 100 were patients having CAD and 40 age matched subjects were included as control group. Data was also recorded from their offspring. High resolution B mode ultrasonography was performed to assess CIMT of carotid arteries. The maximum CIMT of any one side of carotid artery was taken for study.Results: CAD was more prevalent among males (78%). Majority of the offspring of cases had age between 28-42 years and majority were male (73%). Most common risk factors for CAD was dyslipidemia (48%), hypertension (24%), diabetes (12%) and smoking (21%), whereas in offspring’s of CAD patients, dyslipidemia was seen in 28%, hypertension in 3%, diabetes and tobacco smoking in 12% and 24% respectively. The CIMT of CAD patients was significantly increased with increasing the number of risk factors and the same pattern was also seen in controls.  The CIMT of asymptomatic offspring’s having positive family history was significantly more than the asymptomatic offspring without positive family history of CAD.Conclusions: CIMT measurements can be used as a surrogate marker of atherosclerosis as it has showed a direct link with number of risk factors of CAD. 

scholarly journals Quality of Life and Psychological Distress during Cancer: A Prospective Observational Study Involving Liver Cancer Patients

2021 ◽  
pp. 576-585
Author(s):  
Madeeha Malik ◽  
Iqra Parveen Kiyani ◽  
Shazana Rana ◽  
Azhar Hussain ◽  
Muhammad Bin Aslam Zahid
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Liver Cancer ◽  
Medical History ◽  
Cancer Patients ◽  
Study Design ◽  
Negative Impact ◽  
Past Medical History ◽  
Symptom Scale

Introduction: Liver Cancer is aggressive cancer and patients are mostly screened and diagnosed when they become symptomatic at advanced. Disease severity, depression, fatigue, joint pain, and poor appetite have been reported as strong determinants of quality of life (QoL) among liver cancer patients. Aims: The objective of the study was to assess the quality of life and depression among liver cancer patients in Pakistan. Study Design:  A descriptive cross-sectional study design was used. Place and Duration of Study: The study was conducted in healthcare facilities of Islamabad and Rawalpindi, Pakistan between June 2020-December 2020. Methodology: Two pre-validated questionnaires i.e. EORTC QLQ-C30 and HADS were self-administered to a sample of 100 liver cancer patients selected using a convenience sampling technique for measuring QoL and depression, respectively. After data collection, data was cleaned, coded, and entered in SPSS. Results: The results highlighted that the lowest scores observed in the domain of symptom scale were: Nausea and Vomiting (23.72, ± 28.238), Dyspnea (25.27, ± 26.90), Constipation (26.03, ± 34.75) followed by Diarrhea (22.63, ± 28.42), whereas highest scores in the symptom scale were observed in the domain of fatigue (37.69, ± 20.06), pain (40.37, ± 18.44), insomnia (41.65, ± 32.37) and financial difficulties (60.33, ± 33.830). On the other hand, highest score on the functional scale was observed for physical functioning (64, ± 21.76) and the lowest score was observed in social functioning (53.19, ± 20.66). Conclusion: The present study concluded that liver cancer had a negative impact on risk factors/past medical history, co-morbidities, and poor socio-economic of life across all domains along with moderate depression in liver cancer patients. Illiteracy, advanced liver cancer stage, risk factors/past medical history, co-morbidities and poor socio-economic status negatively affected functional and symptom scale. Appropriate health educational and psychological interventional programs targeting patients should be initiated to improve awareness and reduce depression among liver cancer patients.

Long-term observation on postoperative recurrence and complications of transvaginal mesh surgery for pelvic organ prolapse

2021 ◽  
Author(s):  
Junfang Yang ◽  
Kun Zhang ◽  
Jinsong Han ◽  
Yiting Wang ◽  
Ying Yao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pelvic Organ Prolapse ◽  
Protective Factor ◽  
Pelvic Organ ◽  
Vaginal Mesh ◽  
Transvaginal Mesh ◽  
Mesh Exposure ◽  
Mesh Surgery ◽  
Post Menopause

Objective: This study aims to evaluate the risk factors for subjective recurrence and complications of patients who underwent transvaginal synthetic mesh surgery. Design：This retrospective cohort study included patients who received transvaginal mesh (TVM) surgery between January 2005 and June 2019. Methods: The information of patients was collected, including basic characteristics, subjective recurrence, and mesh-related complications. The clinical characteristics of patients with and without subjective recurrence were compared. The sexual activities of patients before and after the operation were recorded. SPSS 20.0 was used for the statistical analysis. Results: A total of 257 patients were included. Among them, 62 (24.1%) patients were lost to follow-up. The median follow-up time was 80 months (12 months, 170 months). Finally, 195 patients were followed up, 11 (5.6%) patients had a subjective recurrence of pelvic organ prolapse, and 26 (13.3%) patients had mesh-related complications (11 patients with de novo pain and 15 patients with mesh exposure). We found significant differences in age (68.9±5.1 vs. 63.4±5.8 years old), years of post-menopause (17.5±6.3 vs. 13.3±6.9 years), previous hysterectomy (27.3% vs. 6.0%), and concomitant hysterectomy (45.5% vs. 81.0%) between patients with and without subjective recurrence (P<0.05). The mesh exposure proportion of patients with total vaginal mesh (47.6%) was significantly higher than that with anterior vaginal mesh (2.9%) (P<0.05). Furthermore, 6.7% of sexually active patients reported do novo dyspareunia. Limitation: The investigators could only record the subjective recurrence of patients, thus there is a lack of objective recurrence data. Conclusion: Age, years of post-menopause and previous hysterectomy are risk factors for subjective recurrence of transvaginal mesh surgery; however，concomitant hysterectomy is a protective factor. Mesh exposure is the most common complication, especially for total vaginal mesh repair surgery.

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