scholarly journals State of cardiovascular system in employees with chronic obstructive pulmonary disease in combination with arterial hypertension in terms of exposure to toxic games

2021 ◽  
Vol 38 (1) ◽  
pp. 16-28
Author(s):  
L. A. Panacheva ◽  
L. A. Shpagina
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Arterial Hypertension ◽  
Cardiovascular System ◽  
Structure And Function ◽  
Chronic Obstructive ◽  
Length Of Service ◽  
Obstructive Pulmonary Disease ◽  
The Right ◽  
And Function ◽  
Large Vessels

Objective. Identification of the features of the cardiovascular system damage in chronic obstructive pulmonary disease (COPD) combined with arterial hypertension (AH) in workers exposed to toxic gases (TG). Materials and methods. 132 house painters and paint production workers of the Novosibirsk aviation enterprise were included in 3 strata and examined: I-COPD and TG; II-COPD in combination with AH when exposed to TG; III COPD in combination with AH without exposure to TG. Employees of all strata were divided by length of service less than 10 and more than 10 years. The selection of workers in groups was carried out by a continuous method. Results. The most pronounced changes on the ECG, regardless of the length of service, were observed in workers with COPD in combination with hypertension and contact with TG (levogram and metabolic changes in the myocardium). When exposed to TG for more than 10 years, hypertrophy of the left parts of the heart was also detected. Among workers with COPD in combination with hypertension exposed to TG, the indicators of average pulmonary artery pressure (APAP) and pulmonary vascular resistance (PVR) elevated with increasing work experience; changes in the structure and function of the right and left parts of the heart and signs of remodeling of large vessels were also revealed. The same workers showed more pronounced changes in the daily blood pressure profile (DBPP) of AP with the prevalence of Non-dippers and Night-pickers. Conclusions. Among workers suffering from comorbid pathology, with increasing duration of TG exposure over 10 years, there were observed the most pronounced ECG changes (deviation of electrical axis to the left, metabolic changes in the myocardium, hypertrophy of the left heart); increased APAP and PVR 1.21 and 1.10 times; changes in the structure and function of the right and left chambers of the heart, remodeling of large vessels; increase in the frequency of variants of the DBPP of Non-dippers and Night-pickers.

The state of the cardiovascular system in occupational bronchitis and chronic obstructive pulmonary disease, not associated with the impact of harmful industrial factors

2021 ◽  
pp. 55-68
Author(s):  
Vyacheslav S. Lotkov ◽  
Anton Vladimirovich Glazistov ◽  
Antonina G. Baykova ◽  
Marina Yuryevna Vostroknutova ◽  
Natalia E. Lavrentieva
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Cardiovascular System ◽  
Pulmonary Disease ◽  
Lung Diseases ◽  
Chronic Obstructive ◽  
External Respiration ◽  
Obstructive Pulmonary Disease ◽  
Occupational Lung Diseases ◽  
The Right ◽  
The Impact

The formation and progression of chronic dust bronchitis and chronic bronchitis of toxic-chemical etiology, chronic obstructive pulmonary disease is accompanied by an increase in the degree of ventilation disorders, echocardiographic signs of hypertrophy and dilatation of the right ventricle are formed, typical for chronic pulmonary heart disease. The progression of disturbances in the function of external respiration in dusty lung diseases leads to a decrease in myocardial contractility. The detection of hemodynamic disturbances at the early stages of the development of occupational lung diseases indicates the need for individual monitoring of the functional state of the cardiovascular system in the process of contact with industrial aerosols, especially in groups of workers with long-term exposure.

Brain Structure and Function in Chronic Obstructive Pulmonary Disease

2012 ◽  
Vol 186 (3) ◽  
pp. 240-245 ◽  
Author(s):  
James W. Dodd ◽  
Ai Wern Chung ◽  
Martin D. van den Broek ◽  
Thomas R. Barrick ◽  
Rebecca A. Charlton ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Brain Structure ◽  
Structure And Function ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Brain Structure And Function ◽  
And Function

scholarly journals Effect of Oxidative Stress on Diaphragm Dysfunction and Exercise Intervention in Chronic Obstructive Pulmonary Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Bingzhi Zhang ◽  
Peijun Li ◽  
Jian Li ◽  
Xiaodan Liu ◽  
Weibing Wu
Keyword(s):  
Oxidative Stress ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Exercise Intervention ◽  
Structure And Function ◽  
Chronic Obstructive ◽  
Positive Role ◽  
Obstructive Pulmonary Disease ◽  
Diaphragm Dysfunction ◽  
And Function

Chronic obstructive pulmonary disease (COPD) can cause extrapulmonary injury such as diaphragm dysfunction. Oxidative stress is one of the main factors causing diaphragm dysfunction in COPD. Exercise plays a positive role in the prevention and treatment of diaphragm dysfunction in COPD, and the changes in diaphragm structure and function induced by exercise are closely related to the regulation of oxidative stress. Therefore, on the basis of the review of oxidative stress and the changes in diaphragm structure and function in COPD, this article analyzed the effects of exercise on oxidative stress and diaphragm dysfunction in COPD and explored the possible mechanism by which exercise improves oxidative stress. Studies have found that diaphragm dysfunction in COPD includes the decline of muscle strength, endurance, and activity. Oxidative stress mainly affects the structure and function of the diaphragm in COPD through protein oxidation, protease activation and calcium sensitivity reduction. The effects of exercise on oxidative stress level and diaphragm dysfunction may differ depending on the intensity, duration, and style of exercise. The mechanism of exercise on oxidative stress in the diaphragm of COPD may include improving antioxidant capacity, reducing oxidase activity and improving mitochondrial function.

scholarly journals Characteristics of the morphofunctional state of the heart, vessels and the endothelial function in patients combined course of chronic obstructive pulmonary disease and arterial hypertension

2013 ◽  
Vol 17 (2 (66)) ◽  
pp. 41-45
Author(s):  
V. G. Deinega ◽  
V. V. Kryvenko
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Carotid Artery ◽  
Arterial Hypertension ◽  
Diastolic Function ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Left And Right ◽  
Systolic And Diastolic Function ◽  
The Right

The study involved 101 patients with chronic obstructive pulmonary disease (COPD), arterial hypertension of stage II (AH) and their combined course. Using echocardiography and Doppler methods we evaluated the parameters of the systolic and diastolic function of the left and right ventricle, the thickness of the intima-media complex (TIMC) of the left and right common carotid artery (CCA), the parameters of the state of the endothelium. A statistically significant increase of the right and left TIMC, a decrease of the index of endothelium-dependent vasodilation, abnormalities of the systolic and diastolic function of the left and right ventricles in patients with a combined course of COPD and AH as compared with those who had COPD or AH have been detected.

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