The Refractory Patient—Managing Diabetes by the Ear

2015 ◽  
Vol 11 (01) ◽  
pp. 32 ◽  
Author(s):  
Sanjay Kalra ◽  
Yashdeep Gupta ◽  
◽  
Keyword(s):  
Drug Therapy ◽  
Pharmacological Therapy ◽  
Evidence Based ◽  
History Taking ◽  
Diabetes Therapy ◽  
Therapeutic Patient Education ◽  
Bidirectional Communication ◽  
Empathic Listening ◽  
Specialist Practice ◽  
Control Diabetes

Refractory, or ‘difficult to control,’ diabetes is a commonly encountered condition in specialist practice. This editorial describes the characteristics of people with diabetes who are unable to achieve optimal glycemic control, despite aggressive drug therapy. It reflects upon the importance of bidirectional communication between patient and physician, and highlights the need for systematic history taking, empathic listening, and therapeutic patient education. The editors call for practicing ‘diabetes therapy by the ear,’ in conjunction with evidence-based pharmacological therapy, to help reduce the prevalence of refractory diabetes.

ON THE PATHOGENESIS OF GASTRODUODENAL ZONE LESIONS IN VARIOUS VARIANTS OF DRUG THERAPY FOR OCCUPATIONAL RESPIRATORY DISEASES

2021 ◽  
Author(s):  
M.V. Sheenkova ◽  
Keyword(s):  
Drug Therapy ◽  
Gastrointestinal Tract ◽  
Occupational Diseases ◽  
Respiratory Diseases ◽  
Pharmacological Therapy ◽  
Industrial Enterprises ◽  
Duodenal Lesions ◽  
Respiratory Pathology ◽  
Gastroduodenal Zone ◽  
Upper Gastrointestinal

Abstract. A survey of workers of large industrial enterprises with occupational diseases of the respiratory system was conducted to assess the dependence of the risk of damage to the upper gastrointestinal tract on the features of pharmacological therapy of respiratory pathology. The specificity of the pathogenesis of gastric and duodenal lesions associated with the properties of drug treatment of occupational respiratory diseases was revealed.

Pharmacogenomics and Precision Psychiatry

2018 ◽  
pp. 96-102
Author(s):  
Julia C. Stingl ◽  
Gonzalo Laje
Keyword(s):  
Genetic Variation ◽  
Clinical Practice ◽  
Drug Therapy ◽  
Mechanisms Of Action ◽  
Molecular Medicine ◽  
Evidence Based ◽  
Broad Definition ◽  
Clinical Syndromes ◽  
Definition Of ◽  
Future Work

Molecular medicine has opened new possibilities of personalized approaches in drug therapy. The development of evidence-based pharmacogenetic guidelines to steer therapy has slowly entered the field of psychiatric therapeutics. Some of the reasons behind the limited progress in psychiatric pharmacogenomics include the broad definition of clinical syndromes, limited knowledge of psychiatric pathophysiology, and limited understanding of psychotropics’ mechanisms of action. Pharmacogenomic markers have been reported for both pharmacodynamic and pharmacokinetic genes. However, only genetic variation in pharmacokinetic genes has shown to be helpful in clinical practice. There is little consensus as to when and if pharmacogenetic tests should be used in psychiatry. There are limited evidence-based dosing guidelines available for actionable gene–drug pairs. Future work in psychiatry may deepen our understanding of the biological underpinnings of psychiatric syndromes and provide the potential for individual tailored therapies.

scholarly journals 1. Evidence-based Drug Therapy

2009 ◽  
Vol 98 (2) ◽  
pp. 299-305
Author(s):  
Hideki Okayama ◽  
Jitsuo Higaki
Keyword(s):  
Drug Therapy ◽  
Evidence Based

History and Examination of the Spine

2018 ◽  
Author(s):  
Maggie Henjum ◽  
Jodi Young
Keyword(s):  
Systematic Approach ◽  
Treatment Plan ◽  
Current Evidence ◽  
Evidence Based ◽  
Strength Testing ◽  
Objective Data ◽  
History Taking ◽  
Thoracic And Lumbar Spine ◽  
Assessment And Treatment ◽  
A Current

An efficient model for history-taking and physical examination of the spine using a current evidence-based approach provides the foundation for a targeted assessment and treatment plan. Taking a history and examining the cervical, thoracic, and lumbar spine may be complex, especially if the clinician does not use a systematic approach for collecting subjective and objective data. Included in this chapter are best evidence strategies for observing a patient’s posture and movement patterns, assessing active and passive range of motion, and performing neurologic testing, strength testing, special tests, and palpation. Special attention is given to test clusters and examination items with strong psychometric properties that provide efficient and accurate examination results. By incorporating these strategies into the history and examination, the examiner should be able to rule in or out particular diagnoses that will direct overall management of the patient’s symptoms.

Developing a paediatric drug formulary for the Netherlands

2016 ◽  
Vol 102 (4) ◽  
pp. 357-361 ◽  
Author(s):  
Tjitske M van der Zanden ◽  
Saskia N de Wildt ◽  
Yves Liem ◽  
Martin Offringa ◽  
Matthijs de Hoog
Keyword(s):  
Drug Therapy ◽  
Drug Use ◽  
The Netherlands ◽  
Evidence Based ◽  
Drug Formulary ◽  
Concerted Effort ◽  
Off Label ◽  
Registration Data ◽  
Current Content ◽  
Professional Guidelines

As many drugs in paediatrics are used off-label, prescribers face a lack of evidence-based dosing guidelines. A Dutch framework was developed to provide dosing guidelines based on best available evidence from registration data, investigator-initiated research, professional guidelines, clinical experience and consensus. This has clarified the scientific grounds of drug use for children and encouraged uniformity in prescribing habits in the Netherlands. The developed framework and the current content of the Dutch Paediatric Formulary could be used as basis for similar initiatives worldwide, preferably in a concerted effort to ultimately provide children with effective and safe drug therapy.

Sign in / Sign up

Export Citation Format

Share Document