Solubility of a Pharmacological Intermediate Drug Isatin in Different Solvents at Various Temperatures

The solubility of isatin in different solvents was studied by a gravimetrical method from (298.15 to 318.15) K under atmospheric pressure and the solubility data were correlated against temperature. The solvents selected for the present study are: water, methanol, ethanol, 1-butanol, dichloromethane, dichloroethane, chloroform and carbon tetra chloride. Among chlorinated solvents, solubility is observed to be maximum in 1, 2-dichloroethane and minimum in dichloromethane whereas in alcohols, maximum solubility is observed in methanol. In water, solubility is found to be minimum. Further, some thermodynamic parameters such as Gibb’s energy (ΔGsol), heat of solution (ΔHsol) and entropy of solution (ΔSsol) have also been evaluated.

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2d-Model of Glow Discharge Atmospheric Pressure Plasma in Helium Formed after Spark Breakdown: Calculation of the Electrophysical and Thermodynamic Parameters

Russian Physics Journal ◽

10.1007/s11182-020-01920-z ◽

2020 ◽

Vol 62 (10) ◽

pp. 1890-1898

Author(s):

V. P. Demkin ◽

S. V. Melnichuk ◽

A. V. Postnikov

Keyword(s):

Glow Discharge ◽

Thermodynamic Parameters ◽

Atmospheric Pressure ◽

Atmospheric Pressure Plasma ◽

Pressure Plasma ◽

Spark Breakdown ◽

2D Model

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Analysis of Water Solubility Data on the Basis of HYBOT Descriptors. Part 3. Solubility of Solid Neutral Chemicals and Drugs

QSAR & Combinatorial Science ◽

10.1002/qsar.200430862 ◽

2004 ◽

Vol 23 (5) ◽

pp. 327-343 ◽

Cited By ~ 24

Author(s):

Oleg A. Raevsky ◽

Olga E. Raevskaja ◽

Klaus-Jürgen Schaper

Keyword(s):

Water Solubility ◽

Solubility Data

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Simultaneous bio-reduction of trichloroethene, trichloroethane, and chloroform using a hydrogen-based membrane biofilm reactor

Water Science & Technology ◽

10.2166/wst.2008.432 ◽

2008 ◽

Vol 58 (3) ◽

pp. 495-501 ◽

Cited By ~ 17

Author(s):

Jinwook Chung ◽

Bruce E. Rittmann

Keyword(s):

Electron Donor ◽

Water Solubility ◽

Chlorinated Solvents ◽

Technological Advance ◽

Biofilm Reactor ◽

Treatment Technology ◽

Chlorinated Compounds ◽

Membrane Biofilm Reactor ◽

One Step ◽

Inhibitory Interactions

The contamination of water by chlorinated solvents is recognized as a serious and widespread problem throughout the industrialized world. Here, we focus on three chlorinated solvents that are among those most commonly detected and that have distinct chemical features: trichloroethene (TCE), trichloroethane (TCA), and chloroform (CF). Because many contaminated waters contain mixtures of the chlorinated solvents, a treatment technology that detoxifies all of them simultaneously is highly desirable. The membrane biofilm reactor (MBfR) is a recent technological advance that makes it possible to deliver H2 gas to bacteria efficiently and safely, despite hydrogen's low water solubility and risk of forming a combustible atmosphere when mixed with air. The objectives of this work are to document whether or not the three chlorinated compounds can be dechlorinated simultaneously in a H2-based MBfR and to determine if competitive or inhibitory interactions affect bio-reduction of any of the solvents. The main finding is a demonstration that directly using H2 as the electron donor makes it possible to bio-reduce combinations of different chlorinated solvents. This finding supports that the H2-based MBfR can treat multiple chlorinated solvents in one step, addressing a common groundwater situation. We saw possible evidence of inhibition by CF at a concentration greater than about 1 μM, competition for H2 from sulfate and nitrate reductions, and possible inhibition of TCE reduction from the accumulation of chloroethane (CA) or chloromethane (CM).

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Water Permeation through Elastomer Laminates, II. SBR/EPDM

Rubber Chemistry and Technology ◽

10.5254/1.3538233 ◽

1986 ◽

Vol 59 (5) ◽

pp. 779-786 ◽

Cited By ~ 3

Author(s):

Patrick E. Cassidy ◽

Tejraj M. Aminabhavi

Keyword(s):

Temperature Dependence ◽

Transport Mechanism ◽

Water Solubility ◽

Salt Water ◽

Activation Energies ◽

Permeation Rate ◽

Solubility Data ◽

Distilled Water ◽

Arrhenius Behavior ◽

Water Permeation

Abstract In summary, the measurements described here suggest that the temperature dependence of permeation rate had an Arrhenius behavior. Activation energies fall within the range expected for those membranes that follow activated transport mechanism. For all single elastomers, salt water exhibited higher permeation rates than did distilled water. The laminates show a directional behavior but more distinctly for distilled water than for salt water. Solubility data alone cannot, however, always account for this phenomenon.

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Solubility of carbon dioxide in alkylcarbonates and lactones

Canadian Journal of Chemistry ◽

10.1139/v03-069 ◽

2003 ◽

Vol 81 (5) ◽

pp. 385-391 ◽

Cited By ~ 27

Author(s):

F Blanchard ◽

B Carré ◽

F Bonhomme ◽

P Biensan ◽

D Lemordant

Keyword(s):

Experimental Data ◽

Carbon Dioxide ◽

Propylene Carbonate ◽

Atmospheric Pressure ◽

Ethylene Carbonate ◽

Solubility Data ◽

Henry's Law ◽

Henry’S Law ◽

Gas Solubilities ◽

Nonpolar Molecules

The solubility of carbon dioxide in γ-butyrolactone (BL), caprolactone (CL), propylene carbonate (PC), ethylene carbonate (EC), dimethylcarbonate (DMC), diethylcarbonate (DEC), and mixtures of these components has been determined at temperatures from 275 to 333 K at atmospheric pressure. The Henry's law constant (kH) for the dissolution of CO2 in these solvents has been deduced from the solubility data. The value of kH increases in the following order: DEC < DMC < PC < CL < BL < EC, which is identical to the order of the Hildebrand parameters (δ) of the corresponding solvents. The accuracy of classical theories for predicting gas solubilities in liquids has been examined. The best results are given by the VilcuPerisamu equation, which is derived from the ScatchardHildebrand theory but takes into account the polarizability of the solute and the permittivity of the solvent. A modified form of the Prausnitz and Shair equation is proposed to estimate the solubility of nonpolar molecules in strongly dipolar solvents. This equation fits the experimental data with improved precision.Key words: alkylcarbonate, lactone, carbon dioxide, liquidgas equilibrium, Henry's law, Hildebrand parameter.

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