scholarly journals Microwave Assisted Synthesis of some Novel Sulphonamide Bearing Pyrazolone Core Structure

2014 ◽  
Vol 30 ◽  
pp. 116-126
Author(s):  
Dipti L. Namera ◽  
Khushal M. Kapadiya ◽  
Mitesh M. Chhatrola ◽  
Umed C. Bhoya
Keyword(s):  
Experimental Data ◽  
Conventional Method ◽  
Mass Spectroscopy ◽  
Elemental Analysis ◽  
Microwave Assisted Synthesis ◽  
H Nmr ◽  
Microwave Assisted ◽  
Pyrazolone Derivatives ◽  
Ft Ir ◽  
Microwave Assisted Method

We have described some novel Sulphonamide bearing pyrazoline derivatives synthesized by conventional method as well as microwave assisted method of synthesis. The reaction of 4-(3-methyl-5-oxo-4,5-dihydro-1-H-pyrazol-1-yl)benzenesulphonamide with substituted benzaldehyde in the presence of Methanol as solvent and piperidine as catalyst, generated a series of substituted pyrazolone derivatives 4a-m. The structures of all synthesized compounds are well characterized by Mass spectroscopy, FT-IR, 1H NMR and elemental analysis. After obtaining experimental data regarding the yield and the time taken for the synthesis by both the approaches, convenient and microwave assisted method, it was ascertained that the microwave assisted method is more suitable for synthesis of pyrazolone derivatives 4a-m.

scholarly journals Convenient Synthesis of the 2,5-di-Substituted 1,3,4-Oxadiazole Derivatives under Microwave

2014 ◽  
Vol 30 ◽  
pp. 159-166
Author(s):  
Dipti L. Namera ◽  
Umed C. Bhoya
Keyword(s):  
Experimental Data ◽  
Cinnamic Acid ◽  
Elemental Analysis ◽  
H Nmr ◽  
Microwave Assisted ◽  
Convenient Synthesis ◽  
Oxadiazole Derivatives ◽  
Ft Ir ◽  
Microwave Assisted Method ◽  
C Nmr

We have reported some novel 1,3,4-oxadiazole synthesized by conventional method as well as microwave assisted method. The reaction of different substituted cinnamic acid 2a-o with 2-(4-chlorophenyl) acetohydrazide by using phosphoric anhydride as catalyst, yielded a series of 2,5-di-substituted 1,3,4-oxadiazole 6a-o. The structures of all synthesized compounds are well characterized by Mass, FT-IR, 1H NMR, 13C NMR and elemental analysis. After obtaining experimental data regarding the yield and the time taken for the synthesis by both the methods, conventional and microwave assisted method, it was proved that the microwave assisted method is convenient for synthesis of this type of 2,5-di-substituted 1,3,4-oxadiazole 6a-o.

Photochemical Reactions of Re(CO)5Br with Ph2P(S)(CH2)nP(S)Ph2 (n = 1,2,3)

2004 ◽  
Vol 59 (7) ◽  
pp. 836-838 ◽  
Author(s):  
Elif Subasi ◽  
Ozan Sanlı Sentürk ◽  
Fadime Ugur (Sarikahya)
Keyword(s):  
Mass Spectroscopy ◽  
Elemental Analysis ◽  
Photochemical Reaction ◽  
Photochemical Reactions ◽  
Bidentate Coordination ◽  
H Nmr ◽  
Nmr Spectrometry ◽  
Ft Ir

The complexes fac-[Re(CO)3Br{Ph2P(S)(CH2)nP(S)Ph2}] [1a, n = 1; 2a, n = 2; 3a, n = 3] and [Re2(CO)8Br2{μ- Ph2P(S)(CH2)nP(S)Ph2}] [1b, n = 1; 2b, n = 2; 3b, n = 3] have been prepared by the photochemical reaction of Re(CO)5Br with Ph2P(S)(CH2)nP(S)Ph2. The products have been characterized by elemental analysis, mass spectroscopy, FT-IR and 31 P-[1H]-NMR spectrometry. The results suggest cis-chelate bidentate coordination of the ligand in fac-1a - 3a and cis-bridging bidentate coordination of the ligand between two metals in 1b - 3b.

scholarly journals Microwave-Assisted Synthesis of Some New Mixed Ligand Ni(II) Complexes Its Characterization and Its Antimicrobial Study

2021 ◽  
pp. 143-152
Author(s):  
Jitendra M. Pawara ◽  
Sunil S. Patil
Keyword(s):  
Thermal Analysis ◽  
Conventional Method ◽  
Mixed Ligand ◽  
High Yield ◽  
Microwave Assisted Synthesis ◽  
Microwave Method ◽  
Preparation Time ◽  
Microwave Assisted ◽  
Microwave Assisted Method ◽  
Very High

Nickel(II) complexes of the type [Ni(P)(L).2H2O] has been synthesized by using 2-amino-6-methyl pyrimidine-4-ol (HP) and amino acids (HL). Complexes synthesized by conventional as well as microwave methods. Results indicate that complexes synthesized by the microwave method are more efficient than the conventional method. In the microwave method preparation time is short (4-7 min.) compared to the conventional method (45 min.). Moreover, the microwave Assisted method gives a very high yield (90%) of the complexes. The microwave method used for the synthesis of the complexes has been found easier, convenient and eco-friendly. Complexes have been characterized by FTIR, Elemental analysis, Gouy experiment, Thermogravimetric Analysis (TGA) and Differential Thermal Analysis (DTA). Complexes have shown significant antimicrobial activity.

scholarly journals Microwave-assisted synthesis of new pyrazole derivatives bearing 1,2,3-triazole scaffold as potential antimicrobial agents

2017 ◽  
Vol 82 (4) ◽  
pp. 357-366 ◽  
Author(s):  
Dongamanti Ashok ◽  
Rangu Kavitha ◽  
Srinivas Gundu ◽  
Rao Hanumantha
Keyword(s):  
Antimicrobial Activity ◽  
Elemental Analysis ◽  
Antimicrobial Agents ◽  
Microwave Assisted Synthesis ◽  
Pyrazole Derivatives ◽  
Inhibitory Effects ◽  
Fungal Strains ◽  
Microwave Assisted ◽  
Cuaac Reaction ◽  
Ft Ir

A new series of (E)-3-(3-(4-substituted phenyl)-1-phenyl-1H-pyrazol- 4-yl)-1-(2-hydroxy-4-((1-aryl-1H-1-2,3-triazol-4-yl)methoxy)phenyl)- prop-2-en-1-one derivatives was synthesized. The synthesis of the title compounds involved the 1,3-dipolar Cu(I)-catalyzed alkyne?azide cycloaddition (CuAAC) reaction of (E)-3-(3-(4-substituted phenyl)-1-phenyl-1H-pyrazol-4- -yl)-1-(2-hydroxy-4-(prop-2-yn-1-yloxy)phenyl)prop-2-en-1-ones with aromatic azides. The structures were confirmed by NMR, FT-IR, mass and elemental analysis. All the synthesized compounds (6a?j) were evaluated for their antimicrobial activity. Compounds 6a, 6d and 6e demonstrated promising inhibitory effects on both bacterial and fungal strains.

scholarly journals Fast Microwave-Assisted Synthesis and Photoluminescence of CaWO4Nanocrystals

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Quanguo Li ◽  
Yanhua Shen ◽  
Taohai Li
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Microwave Assisted Synthesis ◽  
X Ray ◽  
Microwave Assisted ◽  
Transmission Electron ◽  
Ft Ir ◽  
Microwave Assisted Method

In this work, CaWO4nanoparticles have been synthesized by microwave-assisted method at a low temperature of 120°C. The as-prepared powders were characterized by X-ray powder diffraction (XRD), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR). It is found that the reaction time played an important role in the morphology controlling and crystallinity level of CaWO4crystals. The effects of photoluminescent properties have a great relationship with crystallinity.

scholarly journals Synthesis, Characterization, and Electrochemical Behaviour of Cobalt(II) and Nickel(II) Complexes with N2O2 Chelating Ligand 4,4′-(Biphenyl-4,4′-diyldinitrilo)dipentan-2-one

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Lakhdar Sibous ◽  
Embarek Bentouhami ◽  
Mustayeen Ahmed Khan
Keyword(s):  
Schiff Base ◽  
Mass Spectroscopy ◽  
Elemental Analysis ◽  
Electrochemical Behaviour ◽  
Absolute Ethanol ◽  
Molar Ratio ◽  
H Nmr ◽  
Chelating Ligand ◽  
Metal Ligand

4,4′-Diaminobiphenyl reacts with 2,4-pentanedione in absolute ethanol in a molar ratio 1 : 2 to form mainly the product of [1 + 2] condensation, 4,4′-(biphenyl-4,4′-diyldinitrilo)dipentan-2-one (H2L). The Schiff base was used as tetradentate chelating ligand to coordinate CoII and NiII chlorides leading to complexes where the ratio of metal ligand was found to be 2 : 1 or 2 : 2. All the synthesized products were characterized by elemental analysis, infrared, electronic, and mass spectroscopy, 1H NMR, and DSC. The electrochemical behaviour of the ligand and its complexes in DMF is also investigated.

scholarly journals Microwave-assisted synthesis and characterization of some optically active poly(ester-imide) thermoplastic elastomers

e-Polymers ◽  
2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Saeed Zahmatkesh ◽  
Abdol Reza Hajipour
Keyword(s):  
Thermal Analyses ◽  
Specific Rotation ◽  
Thermoplastic Elastomers ◽  
Optically Active ◽  
Microwave Assisted Synthesis ◽  
H Nmr ◽  
Microwave Assisted ◽  
Diacid Chloride ◽  
Elemental Analyses

AbstractPyromellitic dianhydride (1) was reacted with L-leucine (2) to result in [N,N'-(pyromellitoyl)-bis-L-leucine diacid] (3). This compound (3) was converted to N,N'-(pyromellitoyl)-bis-L-leucine diacid chloride (4) by reaction with thionyl chloride. The microwave-assisted polycondensation of this diacid chloride (4) with polyethyleneglycol-diol (PEG-200) and/or three synthetic bisphenols furnish a series of new PEIs and Co-PEIs in a laboratory microwave oven (Milestone). The resulting polymers and copolymers have inherent viscosities in the range of 0.31- 0.53 dl g-1. These polymers are optically active, thermally stable and soluble in polar aprotic solvents such as DMF, DMSO, NMP, DMAc and sulfuric acid. All of the above polymers were fully characterized by IR spectroscopy, 1H NMR spectroscopy, elemental analyses, specific rotation and thermal analyses. Some structural characterizations and physical properties of these optically active PEIs and Co-PEIs are reported.

scholarly journals SYNTHESIS AND STRUCTURAL ELUCIDATION OF AMINO ACETYLENIC AND THIOCARBAMATES DERIVATIVES FOR 2-MERCAPTOBENZOTHIAZOLE AS ANTIMICROBIAL AGENTS

2017 ◽  
Vol 9 (2) ◽  
pp. 192
Author(s):  
Aseel Alsarahni ◽  
Zuhair Muhi Eldeen ◽  
Elham Al-kaissi ◽  
Ibrahim Al- Adham ◽  
Najah Al-muhtaseb
Keyword(s):  
Antimicrobial Activity ◽  
Elemental Analysis ◽  
Antimicrobial Agents ◽  
Diffusion Method ◽  
Benzothiazole Derivatives ◽  
H Nmr ◽  
Ft Ir ◽  
Potential Antimicrobial Activity ◽  
C Nmr

<p><strong>Objective: </strong>To design and synthesize amino acetylenic and thiocarbonate of 2-mercapto-1,3-benthiazoles as potential antimicrobial agents.</p><p><strong>Methods: </strong>A new series of 2-{[4-(t-amino-1-yl) but-2-yn-1-yl] sulfanyl}-1,3-benzothiazole derivatives (AZ1-AZ6), and S-1,3-benzothiazol-2-yl-O-alkyl carbonothioate derivatives were synthesised, with the aim that the target compounds show new and potential antimicrobial activity. The elemental analysis was indicated by the EuroEA elemental analyzer, and biological characterization was via IR, <sup>1</sup>H-NMR, [13]C-NMR, DSC were determined with the aid of Bruker FT-IR and Varian 300 MHz spectrometer using DMSO-d<sub>6</sub> as a solvent.<em> </em><em>In vitro </em>antimicrobial activity, evaluation was done for the synthesised compounds, by agar diffusion method and broth dilution test. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) were determined. <em></em></p><p><strong>Results: </strong>The IR, <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, DSC and elemental analysis were consistent with the assigned structures. Compound of 2-{[4-(4-methylpiperazin-1-yl)but-2-yn-1-yl] sulfanyl}-1,3-benzothiazole (AZ1), 2-{[4-(2-methylpiperidin-1-yl)but-2-yn-1-yl]sulfanyl}-1,3-benzothiazole (AZ2), 2-{[4-(piperidin-1-yl) but-2-yn-1-yl]sulfanyl}-1, 3-benzothiazole (AZ6), S-1,3-benzothiazol-2-yl-O-ethyl carbonothioate (AZ7), and S-1,3-benzothiazol-2-yl-O-(2-methylpropyl) carbonothioate (AZ9) showed the highest antimicrobial activity against <em>Pseudomonas aeruginosa </em>(<em>P. aeruginosa</em>), AZ-9 demonstrated the highest antifungal activity against <em>Candida albicans </em>(<em>C. albicans</em>), with MIC of 31.25 µg/ml.</p><p><strong>Conclusion: </strong>These promising results promoted our interest to investigate other structural analogues for their antimicrobial activity further.</p>

Microwave-assisted synthesis of zinc 5-(4-carboxyphenyl)-10,15,20-triphenylporphyrin and zinc 5-(4-carboxyphenyl)-10,15,20-triphenylchlorin

2015 ◽  
Vol 19 (04) ◽  
pp. 595-600 ◽  
Author(s):  
Rima Chouikrat ◽  
Aymeric Champion ◽  
Régis Vanderesse ◽  
Céline Frochot ◽  
Albert Moussaron
Keyword(s):  
Reaction Times ◽  
Microwave Assisted Synthesis ◽  
Spectroscopic Techniques ◽  
H Nmr ◽  
Microwave Assisted ◽  
Experimental Protocols ◽  
Time Of Reaction

The microwave-assisted synthesis of zinc 5-(4-carboxyphenyl)-10,15,20-triphenylporphyrin and zinc 5-(4-carboxyphenyl)-10,15,20-triphenylchlrorin are described and compared to classic conditions of synthesis in terms of time of reaction and yields obtained. The new experimental protocols are easy to implement required small amounts of reagents and solvents and lead to short reaction times. All compounds have been characterized by 1 H NMR, MS and spectroscopic techniques.

Darstellung und Charakterisierung von 1.4- und 1.5-Dienkomplexen des Platins- Röntgenstrukturanalyse von Dichloro-2.5-diphenyl-1.5-hexadienplatin(II), Cl2Pt((C6H5)2C6H8) / Preparation and Characterization of 1,4- and 1,5-Diene Complexes of Platinum; X-ray Analysis of Dichloro-2,5-diphenyl-1,5-hexadiene Platinum(II), ((Cl2Pt(C6H5)2C6H8)

1980 ◽  
Vol 35 (7) ◽  
pp. 802-807 ◽  
Author(s):  
Michael Kopp ◽  
Luise R. Krauth ◽  
Richard Ratka ◽  
Klaus Weidenhammer ◽  
Manfred L. Ziegler
Keyword(s):  
Mass Spectroscopy ◽  
Elemental Analysis ◽  
X Ray ◽  
H Nmr ◽  
Ray Methods

The reaction of cis-(C6H5CN)2PtCl2 and Na2PtCl4 with the dienes 1,4-pentadiene and 2,5-diphenyl-1,5-hexadiene yields the species cis-(1,4-pentadiene) PtCl2 and cis-(2,5-diphenyl-1,5-hexadiene)PtCl2, respectively. The compounds have been fully characterized by elemental analysis, IR, 1H-NMR, mass spectroscopy and by X-ray methods

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