scholarly journals Assessment of the effectiveness of medical rehabilitation after COVID-19 based on the functional capacity of the cardiovascular and respiratory systems

2021 ◽  
Vol 31 (6) ◽  
pp. 710-717
Author(s):  
Oksana V. Kamenskaya ◽  
Irina Yu. Loginova ◽  
Asya S. Klinkova ◽  
Alexander M. Chernyavsky ◽  
Tatiana A. Bergen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gas Exchange ◽  
Functional Capacity ◽  
Exercise Tolerance ◽  
Rehabilitation Program ◽  
Pulmonary Gas Exchange ◽  
Medical Rehabilitation ◽  
Diffusion Capacity ◽  
Respiratory Systems

Aim. To assess the effectiveness of medical rehabilitation after pneumonia associated with the novel coronavirus infection (COVID-19), based on the study of functional capacity of the cardiovascular system and the external respiratory system.Methods. The study included 70 patients who had COVID-19 pneumonia and underwent a medical rehabilitation program from September to December 2020. Before being included in the rehabilitation program, all patients underwent pulmonary function tests (PFT), including an assessment of the lungs diffusion capacity, cardiopulmonary exercise testing, multispiral computed tomography (MSCT) of the chest, echocardiography, an evaluation of the quality of life according to the SF-36 questionnaire and the severity of shortness of breath on the mMRC scale. The effectiveness of rehabilitation was evaluated against the changes in PFT parameters, exercise tolerance, and quality of life.Results. At the enrollment, 46% of patients retained lung tissue lesions shown by MSCT and accompanied by a decrease in the lung diffusion capacity (67 (55 - 79%) of predicted value), dyspnea of 1.6 (1.0 - 3.0) points according to mMRC scale, moderate level of exercise tolerance and quality of life. Complex cardiopulmonary rehabilitation for 12 - 14 days in a specialized hospital led to a significant improvement in the parameters of pulmonary gas exchange and ventilation, peak oxygen consumption, and an increase in the reserve capacity of the cardiorespiratory system. The factors limiting the improvement of pulmonary gas exchange were the older age of the patients and the increased pressure in the pulmonary artery system. The positive influence of rehabilitation on both the physical and psycho-emotional components of the quality of life was noted.Conclusion. Complex cardiopulmonary rehabilitation with the assessment of changes in the oxygen metabolism parameters and functional capacity of the cardiovascular and respiratory systems has shown to be safe and highly effective in the studied group of patients who have had COVID-19 pneumonia.

scholarly journals Effects of Oral Amino Acid Supplements on Functional Capacity in Patients with Chronic Heart Failure

2014 ◽  
Vol 8 ◽  
pp. CMC.S14016 ◽  
Author(s):  
Carlo Lombardi ◽  
Valentina Carubelli ◽  
Valentina Lazzarini ◽  
Enrico Vizzardi ◽  
Filippo Quinzani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
New York ◽  
Functional Capacity ◽  
Exercise Tolerance ◽  
Stress Test ◽  
Nyha Class ◽  
Heart Association

Amino acids (AAs) availability is reduced in patients with heart failure (HF) leading to abnormalities in cardiac and skeletal muscle metabolism, and eventually to a reduction in functional capacity and quality of life. In this study, we investigate the effects of oral supplementation with essential and semi-essential AAs for three months in patients with stable chronic HF. The primary endpoints were the effects of AA's supplementation on exercise tolerance (evaluated by cardiopulmonary stress test and six minutes walking test (6MWT)), whether the secondary endpoints were change in quality of life (evaluated by Minnesota Living with Heart Failure Questionnaire—MLHFQJ and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels. We enrolled 13 patients with chronic stable HF on optimal therapy, symptomatic in New York Heart Association (NYHA) class II/III, with an ejection fraction (EF) <45%. The mean age was 59 ± 14 years, and 11 (84.6%) patients were male. After three months, peak VO2 (baseline 14.8 ± 3.9 mL/minute/kg vs follow-up 16.8 ± 5.1 mL/minute/kg; P = 0.008) and VO2 at anaerobic threshold improved significantly (baseline 9.0 ± 3.8 mL/minute/kg vs follow-up 12.4 ± 3.9 mL/minute/kg; P = 0.002), as the 6MWT distance (baseline 439.1 ± 64.3 m vs follow-up 474.2 ± 89.0 m; P = 0.006). However, the quality of life did not change significantly (baseline 21 ± 14 vs follow-up 25 ± 13; P = 0.321). A non-significant trend in the reduction of NT-proBNP levels was observed (baseline 1502 ± 1900 ng/L vs follow-up 1040 ± 1345 ng/L; P = 0.052). AAs treatment resulted safe and was well tolerated by all patients. In our study, AAs supplementation in patients with chronic HF improved exercise tolerance but did not change quality of life.

scholarly journals Effects of the combination of metformin and exercise on glycated hemoglobin, functional capacity, lipid profile, quality of life, and body weight

2019 ◽  
Vol 47 (3) ◽  
pp. 1131-1145 ◽  
Author(s):  
Sherif Eltonsy ◽  
Monique Dufour Doiron ◽  
Patrice Simard ◽  
Caroline Jose ◽  
Martin Sénéchal ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lipid Profile ◽  
Functional Capacity ◽  
Glycated Hemoglobin ◽  
Rehabilitation Program ◽  
Directed Acyclic Graphs ◽  
Secondary Outcomes ◽  
6 Minute Walk Test ◽  
The Impact

Objective To evaluate the impact of the combination of metformin and exercise on changes in glycated hemoglobin (HbA1c), functional capacity, the lipid profile, quality of life, and weight. Methods Data from a 12-week cardiovascular rehabilitation program (2014–2016) were retrospectively evaluated. Metformin exposure was determined through recorded prescriptions, and average minutes of exercise per week were computed from exercise logs. The primary outcomes were changes in HbA1c and functional capacity (6-minute walk test [6MWT]) over 12 weeks. The secondary outcomes were changes in the lipid profile, quality of life, and weight. Directed acyclic graphs were used to identify potential confounders, accounted for with multiple linear regression. Results The cohort comprised 403 patients (85 metformin users, 318 non-users). The average amount of exercise was 102.7±48.7 minutes/week among metformin users and 107.7±58.1 minutes/week among non-users. Although changes in HbA1c were similar for both groups, the coefficient for the metformin–exercise interaction indicated significantly greater improvements in the 6MWT among metformin users. There were no between-group differences in any secondary outcomes. Conclusions The combination of metformin and exercise led to greater gains in functional capacity than exercise alone. This combination did not appear to influence the effects of either treatment on other outcomes.

scholarly journals Endurance and Resistance Training in Radically Treated Respiratory Cancer patients: A Pilot Study

2010 ◽  
Vol 2010 ◽  
pp. 1-7
Author(s):  
B. Salhi ◽  
I. Demedts ◽  
A. Simpelaere ◽  
S. Decraene ◽  
K. Vermaelen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pilot Study ◽  
Cancer Patients ◽  
Exercise Capacity ◽  
Exercise Tolerance ◽  
Respiratory Muscle ◽  
Muscle Force ◽  
Rehabilitation Program ◽  
Respiratory Cancer

Introduction. Respiratory cancer and its treatment are known to contribute to muscle weakness and functional impairment.Aim. To assess the effects of rehabilitation in patients with respiratory cancer.Methods. Radically treated respiratory cancer patients were included in a 12-week multidisciplinary rehabilitation program.Results. 16 patients (age: 61 ± 7 years; FEV1: 57 ± 16% pred.) showed a reduced exercise tolerance (VO2max: 56 ± 15% pred.; 6 MWD: 67 ± 11% pred.), muscle force (PImax: 54 ± 22% pred.; QF: 67 ± 16% pred.), and quality of life (CRDQd: 17 ± 5 points; CRDQf: 16 ± 5 points). Exercise tolerance, muscle force, and quality of life improved significantly after rehabilitation.Conclusion. Radically treated patients with respiratory cancer have a decreased exercise capacity, muscle force, and quality of life. 12 weeks of rehabilitation leads to a significant improvement in exercise capacity, respiratory muscle force, and quality of life.

scholarly journals Quality of life and functional capacity one year after coronary artery bypass graft surgery

2011 ◽  
Vol 58 (3) ◽  
pp. 81-86 ◽  
Author(s):  
Una Nedeljkovic ◽  
Nevena Krstic ◽  
Slavica Varagic-Markovic ◽  
Svetozar Putnik
Keyword(s):  
Quality Of Life ◽  
Coronary Artery ◽  
Functional Capacity ◽  
Mental Component Summary ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Rehabilitation Program ◽  
Artery Bypass Graft ◽  
One Year

Objectives: To analyze functional capacity and quality of life of patients one year after coronary artery bypass graft surgery (CABG) and identify factors that influence them in order to accomplish maximal recovery. Methods: Observational study included 89 patients undergoing elective CABG, who were tested preoperatively and one year after operation using Short form 12 item health survey (SF-12), Duke Activity Status Index (DASI) questionnaire and questionnaire regarding participation in rehabilitation program. Results: After one year, DASI and quality of life-physical component summary score (SF-12 PCS) significantly improved (p<0.001; p<0.05). No statistically significant improvement in mental component summary has been registered. In domains of physical component summary, only general health was significantly better (p<0.05). There was moderate correlation of SF-12 PCS postoperatively with SF-12 mental component summary (SF-12 MCS) preoperatively. DASI scores preoperatively and postoperatively are found to be significantly higher in men comparing to women (p<0.05). Multiple regression analysis found DASI preoperatively (R2=0.62, ?=0.42, p<0.05) and age (?=-0.53, p<0.05) to be significant predictors of DASI postoperatively in women. Enrollment in rehabilitation program didn?t influence DASI and SF-12 scores one year after CABG. Conclusions: Although functional capacity and physical component of quality of life improved, factors that influence them still remain unclear. It seems that mental health status and personality profile, as well as the alternative modalities of rehabilitation, might play important role in long lasting effects of improvement.

scholarly journals Effect of a virtual cardiac rehabilitation program on patients with hypertension: A randomized trial

2021 ◽  
Vol 34 ◽  
Author(s):  
Luana Aparecida Brandão Leandro ◽  
Gabriella Cruz Ramos de Araújo ◽  
João Paulo Prado ◽  
Tarcísio Nema de Aquino ◽  
Juscelio Pereira da Silva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Muscle Strength ◽  
Cardiac Rehabilitation ◽  
Functional Capacity ◽  
Rehabilitation Program ◽  
Physical Conditioning ◽  
Post Intervention ◽  
Arterial Blood

Abstract Introduction: Hypertension is among the main primary factors for the cause of death from cardiovascular diseases. Among the treatments for hypertension, physical exercise has stood out. However, the adherence of patients with hypertension to the practice of physical exercises is low, and thus strategies such as virtual rehabilitation may be beneficial, in addition to increasing adherence. Objective: This study aimed to evaluate the effect of a virtual cardiovascular rehabilitation (VCR) program on arterial blood pressure, physical conditioning and the quality of life of patients with hypertension. Methods: This is a randomized clinical trial with 59 patients with hypertension, divided into three groups: conventional cardiac rehabilitation (CCR), VCR and control (CO). Before and after the intervention period the patients were submitted to anthropometric data (BMI, body mass index), vital data (SBP, systolic blood pressure; DBP, diastolic blood pressure), quality of life (SF-36 questionnaire), respiratory muscle strength (MIP, maximum inspiratory pressure; MEP, maximum expiratory pressure) and functional capacity (6-MWT, six-minute walk test) assessment. Both VCR and CCR groups underwent aerobic training. Results: VCR protocol increased functional capacity (p < 0.001), expiratory muscle strength (p < 0.002), and quality of life in the domains in relation to limitation of physical (p < 0.018), emotional aspects (p < 0.019), social aspects (p < 0.042), and mental health (p < 0.002) when baseline and post-intervention were compared. Conclusion: The VCR program is an effective treatment strategy for improving the physical capacity and quality of life of patients with hypertension.

scholarly journals Priorities of medical rehabilitation of patients with recent experience of transient ischemic attack

2021 ◽  
pp. 22-33
Author(s):  
E. V. Kostenko ◽  
L. V. Petrova ◽  
M. A. Eneeva ◽  
V. G. Kravchenko
Keyword(s):  
Quality Of Life ◽  
Antithrombotic Therapy ◽  
Social Activity ◽  
Rehabilitation Program ◽  
Medical Rehabilitation ◽  
Recent Experience ◽  
Neuropsychological Disorders ◽  
Cerebrovascular Events ◽  
Physical Disorders

Introduction. Transient ischemic attacks can be a predictor of a more severe cardiovascular event, the risk of which depends on many factors that requires a personalized approach. Neuropsychological disorders (cognitive, emotional) have a significant impact on quality of life and social activity and are often underestimated in patients with TIA. Comprehensive medical rehabilitation with the inclusion of antithrombotic therapy and psychocorrection measures may reduce the risk of recurrent cardiovascular events in patients with TIA.Purpose of the study: to substantiate the efficiency of complex medical and non-pharmacological rehabilitation in patients who underwent TIA by analyzing the characteristics of the main and leading concomitant diseases.Materials and methods. The morbidity of 351 TIA patients was studied and analyzed. The average age of the examined patients was 58.6 ± 2.2 years, there were 64.9% of women and 35.1% of men. All patients received an individualized medical rehabilitation program for 12 months with correction of identified neuropsychological disorders. Depending on background and concomitant diseases the antiplatelet or anticoagulants therapy was differently administrated.Results and dicussion. Psychological, cognitive, and physical disorders (based on subjective complaints) are common in patients with TIA. The prevalence of mental disorders in patients with TIA was 138.2 cases per 100 patients. The correction of cognitive impairment, depressive symptoms is associated with improved quality of life (p < 0.05). Repeated acute cerebrovascular events (TIA, ischemic stroke) were recorded during the first 6 months after TIA in 29 patients (10.4%) with severe stenosis of the brachiocephalic arteries, severe arterial hypertension and paroxysmal atrial fibrillation.Conclusion. The importance of comprehensive medical and social rehabilitation of patients with TIA is determined. The participation of a psychotherapist as a member of a multidisciplinary team is necessary. A significant role of the secondary prevention of acute cerebrovascular events is assigned to rational antithrombotic therapy.

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