scholarly journals A clinical perspective on food-relatA Clinical Perspective on Food-Related Diseases in the First Year of Lifeed diseases in the first year of life

2020 ◽  
Vol 8 (10) ◽  
Author(s):  
Russell Hopp

Food-related disease processes can have a wide presentation picture. We present here a review of their clinical patterns in infants to allow a prompt diagnosis and appropriate management. Included in the discussion in infants from birth to 12 months includes IgE-mediated food allergy, food protein–induced allergic proctocolitis , food protein enterocolitis syndrome, atopic dermatitis, eosinophilic esophagitis, and eosinophilic gastrointestinal disease. The bibliography is updated to the past two years unless the latest guideline pre-dated 2018, or the reference was of a classic nature.

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Dalal Alkazemi ◽  
Munirah Albeajan ◽  
Stan Kubow

Objective. Early feeding and infant exposures have been suggested as potential risk factors for immunoglobulin E- (IgE-) mediated food allergy (FA). We aimed to evaluate the association between IgE-mediated FA in children and early exposures including the child’s nutritional status, breastfeeding and its duration, the age at which the solid food was first introduced, antibiotic exposure during the first year of life, and the child’s vitamin D status during infancy. Design. A case-control study. Setting and Subjects. Children aged 0–13 years were recruited from pediatric allergy and immunology clinics (PAICs) located at major government hospitals in Kuwait (total FA cases: n=100; boys = 67%), and healthy controls (n=100, boys 55%) were recruited from various vaccination units at primary healthcare centers. Results. Cow’s milk allergy was the most common type of FA. FA status was independently associated with the early exposures of exclusive breastfeeding (aOR = 15.55 (3.26–74.19), p=0.001), vitamin D deficiency or insufficiency during infancy (aOR = 5.42 (1.92–15.30), p=0.001), and antibiotic exposure during the first year of life (aOR = 5.00 (1.58–15.84), p=0.006). Conclusions. FA is highly prevalent among children in Kuwait, and our data indicate that early nutrition-related and antibiotic exposures are associated with FA risk.


PEDIATRICS ◽  
2021 ◽  
Vol 148 (Supplement 3) ◽  
pp. S35-S36
Author(s):  
Monica T. Kraft ◽  
David Stukus

2012 ◽  
Vol 1 (2) ◽  
pp. 11-16
Author(s):  
Amina Asif Siddiqui

The age old understanding that an individual with a hearing loss is incapable of acquiring verbal communication skills was readily accepted in the past, which led to the inadvertent but unfortunate coining of phrases “deaf and dumb” or “deaf and mute, " and the development of non-verbal or manual communication methodolgies of Sign language. Further, this caused the segregation and isolation of otherwise physically and intellectually competent individuals from mainstream society, unjustifiably denying them opportunities of education and vocation. Studies have proved that in the absence of any organic or inorganic complication, a child with a hearing loss may not only score a high Intelligence Quotient but can also acquire more than one language fluently. Early Intervention with appropriate amplification of residual hearing is underscored as the fundamental prerequisite for children with bilateral congenital profound sensorineural hearing loss, for subsequent acquisition of good listening and normal speech-language skills and plausible bilingualism; that further equips them with scholastic achievements comparable to their hearing peers. The past half century has witnessed stupendous technological enhancements in amplification devices manufactured for children having hearing loss, complemented by steady success in fostering their Inclusive Education. This paper highlights the urgent need in Pakistan to address this issue as well as the importance of early detection, diagnosis, and (re)habilitation along with parent training initiated within the first year of life. An otherwise anticipated disabling condition may be overcome completely if neonatal screening, which is not only inexpensive but also easy to perform; is made mandatory at all hospitals and maternity homes, as practiced in the developed world. This shall ease the challenges faced by the families of children having hearing loss; and enable the professionals working with them to successfully alleviate their communicative, social, educational and vocational difficulties, and ensure that they become successfully contributing members of our verbal society.


2020 ◽  
pp. 24-32
Author(s):  
R.V. Marushko ◽  
◽  
О.О. Dudina ◽  
T.L. Marushko ◽  
◽  
...  

Ukraine entered the 21st century with one of the worst vital signs in Europe and the burden of many socio-economic and demographic problems. Adverse quantitative and especially qualitative indicators of population reproduction have become stable. Therefore, the most important medical and social task and one of the main activities of the Ministry of Health of Ukraine is the formation and maintenance of public health. The defining stage in the formation of human health is the first year of life. Purpose — to study the state and trends of changes in the main indicators of the health of children in the first year of life for the period 2000–2019. Materials and methods. A retrospective analysis of the incidence of children in the first year of life, infant mortality, over the past 20 years in the context of individual pathological conditions is carried out. The information base of the study was the data of state and industry statistics for 2000–2019. Methods of a systematic approach, statistical data processing, epidemiological analysis of graphic images were used. Results. The study revealed that the unfavorable demographic situation in Ukraine is accompanied by an unsatisfactory state of the main predictors of a healthy start in the life of infants, the formation and maintenance of their health. Over the past two decades, there has been a high level with a negative trend of diseases of the reproductive system of women, a high frequency of the combination of pregnancy and extragenital diseases remains. There is a negative trend towards an increase in the generalized objective criterion of the health of the generation, which is born and the socio-economic well-being of the population — the frequency of premature, low birth weight, incl. With very low birth weight. Only thanks to the introduction of modern medical organizational technologies with proven efficiency in the activities of the maternal and child health service was it possible to achieve a decrease in the incidence of newborns from 280.8 per 1000 live births in 2000 up to 172.14 in 2019. At the same time, the increase in the incidence of newborns with diseases that have a direct impact on the development of chronic and disabling diseases at all stages of life is of concern — congenital pneumonia, neonatal sepsis, other disorders of the cerebral status of the newborn, neonatal jaundice. According to the assessment of the dynamics of the general morbidity of children in the first year of life, its level is still high, with a positive trend — 2018.8 per 1000 children who reached 1 year in 2000 and 1393.1 in 2019, the growth rate is -30.9% with a traditionally leading position in the level and structure of the incidence of respiratory diseases — 810.2 per 1000 children who have reached one year of life and 58.15%, certain conditions occurring in perinatal period — 126.7 ‰ and 9.06%, diseases of the skin and subcutaneous tissue — 63.9‰ and 4.59%, diseases of the blood and hematopoietic organs and certain disorders involving the immune mechanism — 63.0‰ and 4.52%. Conclusions. The positive dynamics of morbidity in children of the first year of life is confirmed by a decrease in infant mortality from its maximum level of 11.9 per 1000 live births in 2000 up to 7.0 in 2019, the growth rate is -41.2% due to all its components with a more intensive reduction in postneonatal mortality from 5.28‰ to 2.57‰, the growth rate is -51.3% against the background of an increase in the concentration of mortality in the neonatal period from 55.9% to 64.5%, respectively. No conflict of interest was declared by the authors. Key words: newborns, children of the first year of life, low birthweight newborns, morbidity, infant mortality.


2021 ◽  
Vol 26 (3) ◽  
pp. 173-176
Author(s):  
Elissa M Abrams ◽  
Kyla J Hildebrand ◽  
Edmond S Chan

Abstract The most common types of non-IgE-mediated food allergy are food protein-induced enterocolitis syndrome (FPIES) and food protein-induced allergic proctocolitis (FPIAP). FPIES presents with delayed refractory emesis, while FPIAP presents with hematochezia in otherwise healthy infants. Acute management of FPIES includes rehydration or ondansetron, or both. No acute management is required for FPIAP. Long-term management of both disorders includes avoidance of the trigger food. The prognosis for both conditions is a high rate of resolution within a few years’ time.


PEDIATRICS ◽  
2020 ◽  
Vol 146 (3) ◽  
pp. e20200202
Author(s):  
Victoria M. Martin ◽  
Yamini V. Virkud ◽  
Neelam A. Phadke ◽  
Kuan-Wen Su ◽  
Hannah Seay ◽  
...  

PEDIATRICS ◽  
1970 ◽  
Vol 45 (6) ◽  
pp. 960-962
Author(s):  
Clarence H. Webb

In view of the fact that this reviewer has spent a considerable part of his professional career rendering the type of service which Dr. Anderson decries as unnecessary, it is difficult to review the article without doing what the author found difficult to avoid, which is to be swayed by preconceptions. It is hoped that the author will temper his bias with the reviewer's bias to bring conclusions and recommendations out of the study which the figures justify and which are nearer the middle of the road. There are physicians in pediatrics who consider regular examination of infants and children to be desirable and productive; there are physicians who prefer that a variety of methods be used in pediatrics until it is fully demonstrated that one is superior to the other and do not wish to be forced into a "new pediatrics" unless it is demonstrably better; and, there are parents who bring their babies to pediatricians for reasons other than those mentioned, i.e., for treatment or prevention of abnormal conditions. Their babies are precious commodities and they wish to know that the babies do not have abnormalities but also want reassurance that they are caring for the babies properly, affording them attention and supervision which is not just good but is superior, and being good parents who are helping their babies in every way to develop the best of their potentials. Herein lies an innate difference between public health and private health in pediatrics which seems to have been highly desirable to pediatricians and parents in the past.


2020 ◽  
Vol 16 (2) ◽  
pp. 95-105
Author(s):  
Antonella Cianferoni

Food allergies, defined as an immune response to food proteins, affect as many as 8% of young children and 2% of adults in western countries, and their prevalence appears to be rising like all allergic diseases. In addition to well-recognized urticaria and anaphylaxis triggered by IgE antibody– mediated immune responses, there is an increasing recognition of cell-mediated disorders, such as eosinophilic esophagitis and food protein–induced enterocolitis. Non-IgE-Mediated gastrointestinal food allergies are a heterogeneous group of food allergies in which there is an immune reaction against food but the primary pathogenesis is not a production of IgE and activation of mast cells and basophils. Those diseases tend to affect mainly the gastrointestinal tract and can present as acute (FPIES) or chronic reaction, such as Eosinophilic Esophagitis (EoE), Food Protein-Induced Allergic Proctocolitis (FPIAP). The role of food allergy in Non-EoE gastrointestinal Eosinophilic disorders (Non- EoE EGID) is poorly understood. In some diseases like EoE, T cell seems to play a major role in initiating the immunological reaction against food, however, in FPIES and FPIAP, the mechanism of sensitization is not clear. Diagnosis requires food challenges and/or endoscopies in most of the patients, as there are no validated biomarkers that can be used for monitoring or diagnosis of Non-IgE mediated food allergies. The treatment of Non-IgE food allergy is dependent on diet (FPIES, and EoE) and/or use of drugs (i.e. steroids, PPI) in EoE and Non-EoE EGID. Non-IgE mediated food allergies are being being investigated.


The Holocene ◽  
2021 ◽  
pp. 095968362110665
Author(s):  
Fernando Arenas ◽  
Harumi Fujita ◽  
Alberto Sánchez

Oceanic characteristics of the Holocene are used to understand climatic patterns and phenomena that affect marine and human communities. Likewise, past marine conditions can be reconstructed from surface sea temperature (SST), using stable oxygen isotopes in bivalve shells. The objective of this study was to calculate Holocene summer SSTs for La Paz Bay, by analyzing δ18O of 14C dated bivalve shells ( Chione californiensis) from a Holocene camp site located in Cañada de La Enfermería, Baja California Sur, México. Aragonite was extracted from the shells’ umbo, representing the summer growth season during the first year of life. δ18O value of C. californiensis is −1.9 ± 0.1‰ at present, and varied between −1.3‰ and −2.6‰ during the last 9 ky. In 9469 BP, 8396 BP, and 7708 BP, δ18O values were similar to those of the present. In 7857 BP, 7805 BP, and 7804 BP, δ18O was 18O depleted (0.6–0.9‰), indicating warmer summer SSTs versus the present. In 7070 BP, 6945 BP, and 2087 BP, δ18O was enriched in 18O (0.3–0.4‰), suggesting colder SSTs versus the present. This study coincides with other paleotemperature studies for the region and allows us to address the effect of changing SST on this marine resource, its use by human communities of the past, and its effects on human presence in the area with respect to climate variability.


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