scholarly journals The protective effect of Withania somnifera against oxidative damage caused by ethanol in the testes of adult male rats

Author(s):  
Divya Bhargavan ◽  
B. Deepa ◽  
Harish Shetty ◽  
A. Krishna
2018 ◽  
Vol 391 (7) ◽  
pp. 729-742 ◽  
Author(s):  
Rania I. Nadeem ◽  
Hebatalla I. Ahmed ◽  
Bahia M. El-Sayeh

2016 ◽  
Vol 21 (4) ◽  
pp. 250-253 ◽  
Author(s):  
Mohammad Waheed El-Anwar ◽  
Said Abdelmonem ◽  
Ebtessam Nada ◽  
Dalia Galhoom ◽  
Ahmed A. Abdelsameea

Objectives: To find out the possible protective effect of cilostazol against amikacin-induced ototoxicity. Methods: This study was carried out on 24 adult male rats classified into 4 equal groups of 6 animals each. (1) The control group was administered saline (1 ml/day, p.o.) for 14 days. (2) The amikacin group was administered amikacin (200 mg/kg, i.m.) once daily for 14 days. (3) The cilostazol-amikacin (14 days) group was administered cilostazol (30 mg/kg, p.o.) once daily and amikacin (200 mg/kg, i.m.) once daily for 14 days. (4) The cilostazol (28 days)-amikacin (14 days) group was administered cilostazol (30 mg/kg, p.o.) once daily for 28 days and amikacin (200 mg/kg, i.m.) once daily for 14 days. Changes in the transient evoked otoacoustic emissions (TEOAEs) in the 4 groups were interpreted statistically. Results: No reported significant differences in TEOAE levels were detected between the groups at the start of the study. In all frequency bands, TEOAEs disappeared after amikacin treatment in the amikacin-alone group and remained absent in the amikacin-cilostazol (14 days) group, while TEOAEs reappeared in the amikacin-cilostazol (28 days) group. Conclusion: Cilostazol treatment for 28 days had a protective effect against amikacin-induced ototoxicity in rats.


2016 ◽  
Vol 81 ◽  
pp. 439-452 ◽  
Author(s):  
Siti Hajar Adam ◽  
Nelli Giribabu ◽  
Normadiah Kassim ◽  
Kilari Eswar Kumar ◽  
Manuri Brahmayya ◽  
...  

2017 ◽  
Vol 42 (4) ◽  
Author(s):  
Mahgoub Mohamed Ahmed

AbstractObjective:The objective of the current study is to investigate the protective effect ofMethods:Forty adult male albino rats were divided into four groups as control,Results:The results showed that, administration of EtOH caused a significant decrease (p<0.05) in serum total protein and albumin, whereas ALT and AST and lipid peroxidation (LPO) were increased following EtOH treatment.Conclusion:had a hepatoprotective role against EtOH-induce oxidative stress and inflammation in rat liver.


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